Establishing a 3D Spheroid Model of Cholinergic Neurons from SH-SY5Y Cells for Neurotoxicity Assessment by Felipe Franco-Campos, Mónica Fernández-Franzón, Yelko Rodríguez-Carrasco, María-José Ruiz

“…SH-SY5Y cells, an immortalized human neuroblastoma cell line, provide a more accessible alternative for studying neuronal processes and neurotoxicity. …”
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A DEM super resolution reconstruction method based on normalizing flow by Jie Yu, Yangtenglong Li, Xuan Bai, Ronghao Yang, Mengxue Cui, Haohao Wu, Zheng Li, Fangzheng Su, Ze Li, Taohuai Liang, Hongliang Yan

“…The negative log-likelihood function and pixel loss function are used to accelerate the optimization to generate high-resolution DEM images that are closer to the natural terrain. …”
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Contrasting responses of soil bacterial and fungal networks to photovoltaic power station by Teng Li, Leilei Lu, Ziqing Kang, Huijun Li, Jihua Wu, Weiguo Du

“…These findings provide new evidence that soil bacterial networks are more sensitive to PV panels installation than fungal networks, deepening our understanding of land-use change effects on soil ecosystem functions. …”
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Control of Regime of Unified Interphase Power Controller by the Use of Rotary Transformer by Kalinin L.P., Zaitsev D.A., Kaloshin D.N, Golub I.V.

“…The increase of IPC controllability allows assigning some control function upon them and ensuring a more favorable operation of the energy system generators. …”
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Cell type-specific driver lines targeting the Drosophila central complex and their use to investigate neuropeptide expression and sleep regulation by Tanya Wolff, Mark Eddison, Nan Chen, Aljoscha Nern, Preeti Sundaramurthi, Divya Sitaraman, Gerald M Rubin

“…Genetic tools for manipulating individual cell types, and knowledge of what neurotransmitters and neuromodulators they express, will be required to gain mechanistic understanding of how these functions are implemented. We generated and characterized split-GAL4 driver lines that express in individual or small subsets of about half of CX cell types. …”
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Improved YOLOv5s With Coordinate Attention for Small and Dense Object Detection From Optical Remote Sensing Images by Qinggang Wu, Yonglei Wu, Yang Li, Wei Huang

“…Third, we replace the commonly used complete intersection over union (IoU) loss function in YOLOv5s with the AW-IoU loss function based on both α-IoU and wise-IoU. …”
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Cisplatin-Induced Stria Vascularis Damage Is Associated with Inflammation and Fibrosis by Na Zhang, Jing Cai, Lei Xu, Haibo Wang, Wenwen Liu

“…The stria vascularis (SV) generates the endocochlear potential (EP) in the inner ear and is necessary for proper hair cell (HC) mechanotransduction and hearing. …”
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Mitochondrial Dysfunction in Glycogen Storage Disorders (GSDs) by Kumudesh Mishra, Or Kakhlon

“…Deficiencies in enzymes responsible for glycogen breakdown and synthesis can impair mitochondrial function. For instance, in GSD type II (Pompe disease), acid alpha-glucosidase deficiency leads to lysosomal glycogen accumulation, which secondarily impacts mitochondrial function through dysfunctional mitophagy, which disrupts mitochondrial quality control, generating oxidative stress. …”
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High resolution genome wide binding event finding and motif discovery reveals transcription factor spatial binding constraints. by Yuchun Guo, Shaun Mahony, David K Gifford

“…An essential component of genome function is the syntax of genomic regulatory elements that determine how diverse transcription factors interact to orchestrate a program of regulatory control. …”
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Insulin Secretion Defect in Children and Adolescents with Obesity: Clinical and Molecular Genetic Characterization by Helena Enders-Seidlitz, Klemens Raile, Maolian Gong, Angela Galler, Peter Kuehnen, Susanna Wiegand

“…We calculated Matsuda index, the area under the curve (AUC (Ins/Glu)), and an oral disposition index (ISSI-2) to estimate insulin resistance and beta-cell function. We identified patients with IGR and low insulin secretion (maximum insulin during OGTT<200 mU/l) and tested a subgroup using next generation sequencing to identify possible mutations in 103 candidate genes. …”
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Aerodynamic Optimization Method for Propeller Airfoil Based on DBO-BP and NSWOA by Changjing Guo, Zhiling Xu, Xiaoyan Yang, Hao Li

“…The NACA4412 airfoil is selected as the research subject, optimizing the original airfoil at three angles of attack (2°, 5° and 10°). The CST (Class Function/Shape Function Transformation) airfoil parametrization method is used to parameterize the original airfoil, and Latin hypercube sampling is employed to perturb the original airfoil within a certain range to generate a sample space. …”
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Systems genetic analysis of osteoblast-lineage cells. by Gina Calabrese, Brian J Bennett, Luz Orozco, Hyun M Kang, Eleazar Eskin, Carlos Dombret, Olivier De Backer, Aldons J Lusis, Charles R Farber

“…In conclusion, we have identified a physiologically relevant gene network and used it to discover novel genes and regulatory mechanisms involved in the function of osteoblast-lineage cells. Our results highlight the power of harnessing natural genetic variation to generate co-expression networks that can be used to gain insight into the function of specific cell-types.…”
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A Comparative Analysis of Attitudes Toward Sexual Orientation and Gender Identity Minority People by B. J. Rye, Rebecca Goldszmidt

“…Attitudes toward sexual and gender minority people is a generative field of study leading to theoretical and practical advances. …”
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Approximate Bayesian Computation for a Dual-Failure-Modes Models and Its Application to Failure Times Data by Mustapha Muhammad, Badamasi Abba, Jinsen Xiao

“…We practically demonstrate approximate Bayesian computation (ABC)-Gibbs scheme using Kolmogorov-Smirnov as distance function; this method is a simulation-based scheme, which the explicit formulation of the likelihood function is not required, hence, suitable for a complex model or big data, where the &#x201C;accept-reject&#x201D; mechanism is required for the posterior computation. …”
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Bone organoid 3D bioprinting: Construction and application in bone regeneration by Tang Zihui, Zhong Chang, Luo Jiayu, Wang Qi, Zhou Ping

“…In recent years, organoid technology has emerged as a promising strategy for bone regeneration, but developing bone organoids with complex structure and function still faces many hurdles. Three-dimensional (3D) bioprinting, a revolutionary additive manufacturing technology, can precisely deposit bioink layer by layer with a specific pattern to construct the required 3D structure, which provides a simpler and more efficient method for generating bone organoids. …”
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Haplotype-resolved genomes of Trichophyton mentagrophytes and Trichophyton tonsurans by Sijie Feng, Zhenhui Wang, Kainan Lin, Kun Wang, Shuting Zheng, Qianqian Wang, Lianyu Lin, Yunkun Lu

“…BUSCO analysis of the assemblies revealed approximately 99% of genome completeness. More than 7500 protein-coding genes were identified, and over 99% of the genes were well annotated through multiple gene function databases. …”
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Industrial sewing as a creative resource in the clothing Surface Design project by Ana Cláudia de Abreu, Marizilda dos Santos Menezes

“… The production of clothing has several operational steps, such as industrial sewing, which is used on textile surfaces as a materialization resource, that is, the union of two or more layers of fabrics by sewing points that makes the object tridimensional. …”
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The New Scramble for Faure Sequence Based on Irrational Numbers by Ali Mogharrabi O., Behrooz Fathi V., M. H. Behzadi, R. Farnoosh

“…In addition, a new form of radical inverse function has been defined, which by combining it with our new matrix, we will have a sequence that not only has a better close uniform distribution than the previous sequences but also is a more accurate and efficient tool in estimating test integrals.…”
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The Influence of Slowly Varying Mass on Severity of Dynamics Nonlinearity of Bearing-Rotor Systems with Pedestal Looseness by Mian Jiang, Jigang Wu, Shuangqi Liu

“…It can be concluded that larger amplitude coefficients of the disk mass varying will have more influence on the severity of dynamics nonlinearity and generation of chaotic behaviors in rotor systems with pedestal looseness.…”
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Mechanical Performance of Actuators in an Active Orthosis for the Upper Extremities by Roland Wiegand, Bastian Schmitz, Christian Pylatiuk, Stefan Schulz

“…The system consists of two special designed fluidic actuators which are used for supporting the elbow function and the internal rotation of the shoulder. …”
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