AGREE: an upper limb motorized exoskeleton for restoring arm functions: a single-blinded randomized controlled trial by Marta Gandolla, Beatrice Luciani, Valeria Longatelli, Peppino Tropea, Agnese Seregni, Massimo Corbo, Francesco Braghin, Alessandra Pedrocchi

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Novel role of microphthalmia-associated transcription factor in modulating the differentiation and immunosuppressive functions of myeloid-derived suppressor cells by Yoon Kyung Jeon, Aram Lee, Haesun Park, Soyoung Lim, Jihyun Lim, Jaemoon Koh, Young Yang, Myeong-Sok Lee, Jong-Seok Lim

“…Furthermore, IHC staining of human tumor tissues revealed that MITF+ MO-MDSCs are more frequently observed in tumor tissues than in tumor-free draining lymph nodes obtained from patients with cancer.Conclusions Our results indicate that MITF regulates the differentiation and function of MDSCs and can be a novel therapeutic target for modulating MDSC activity in immunosuppressive TMEs.…”
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Enhancement of the operating time of the overcurrent relay of the distribution network with high-level penetration of renewable energy sources by Mahmoud Aref, Mahmoud A. Mossa, Emad Abdelkarim, Khairy Sayed, Mishari Metab Almalki, Alaa F.M. Ali

“…The calculation of the output current of distribution generation (DG) units interfaced with an inverter during the fault is a major issue for isolated and grid-connected distributed networks. …”
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The Unpaved Road of Non-Coding RNA Structure–Function Relationships: Current Knowledge, Available Methodologies, and Future Trends by Ana Lúcia Leitão, Francisco J. Enguita

“…Non-coding RNA action is predominantly driven by sequence and structural motifs that interact with specific functional partners. Despite the exponential growth in primary RNA sequence data facilitated by next-generation sequencing studies, the availability of tridimensional RNA data is comparatively more limited. …”
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CTLA4Ig Improves Murine iTreg Induction via TGFβ and Suppressor Function In Vitro by Nina Pilat, Benedikt Mahr, Martina Gattringer, Ulrike Baranyi, Thomas Wekerle

“…However, since the CD28 pathway is more complex than initially thought, the question arose whether blocking CD80/86 would inadvertently impact immunological tolerance by interfering with Treg generation and function. …”
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A novel spectral transformation technique based on special functions for improved chest X-ray image classification. by Abeer Aljohani

“…We developed a mechanism which converts a given medical image to a spectral space which have a base set composed of special functions. In this study, we propose a chest X-ray image classification method based on spectral coefficients. …”
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Adaptive genetics reveals constraints on protein structure/function by evolving E. coli under constant nutrient limitation by Katja Schwartz, Margie Kinnersley, Charles Ross Lindsey, Gavin Sherlock, Frank Rosenzweig

“…Whole-genome whole-population sequencing makes it possible to identify mutations arising in such populations, to use them to discern functional modules where adaptation occurs, and then map gene structure–function relationships. …”
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Telomerase activity in T-cells as a functional test for pathogenicity assessment of novel genetic variants in telomere biology disorders by Olivia Carlund, Anna Norberg, Pia Osterman, Ida Andersson, Alva Eriksson, Sofie Degerman, Magnus Hultdin

“…We have developed a functional TA assay in patient-derived T-cells based on the Telomeric Repeat Amplification Protocol (TRAP) combined with qPCR. …”
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Role of AI and 3D quantitative computed tomography in obstructive airway diseases in correlation with pulmonary function tests by Amira Abdalla saad, Ahmed M. Osman, Hossam M. Abdelhamid, Mai Mohammad Sedik

“…Results A direct relation was discovered between wall thickness (WT), wall area (WA), and luminal area (LA) of the 3rd-generation bronchus of the right lower lung lobe and forced vital capacity (FVC), while no strong relation was found in the 4th and 5th generations. …”
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Novel Flavin Mononucleotide-Functionalized Cerium Fluoride Nanoparticles for Selective Enhanced X-Ray-Induced Photodynamic Therapy by Anastasia I. Kornienko, Maria A. Teplonogova, Marina P. Shevelyova, Matvei A. Popkov, Anton L. Popov, Vladimir E. Ivanov, Nelli R. Popova

“…In the context of normal cells, these nanoparticles serve the function of antioxidants, maintaining a high level of clonogenic activity. …”
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A fusion analytic framework for investigating functional brain connectivity differences using resting-state fMRI by Yeseul Jeon, Jeong-Jae Kim, SuMin Yu, Junggu Choi, Sanghoon Han, Sanghoon Han

“…The framework involves three steps: first, constructing ROI-based Functional Connectivity Networks (FCNs) to manage resting-state fMRI data; second, employing a Self-Attention Deep Learning Model (Self-Attn) for binary classification to generate attention distributions encoding group-level differences; and third, utilizing a Latent Space Item-Response Model (LSIRM) to extract group-representative ROI features, visualized on group summary FCNs.ResultsWe applied our framework to analyze four types of cognitive impairments, demonstrating their effectiveness in identifying significant ROIs that contribute to the differences between the two disease groups. …”
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FEATURES OF WRITTEN LANGUAGE COMMUNICATION BY MEANS OF THE UKRAINIAN LANGUAGE (on the example of official-business, epistolary and conversational-functional styles) by Catherine S. Bondarchuk, Olha A. Chumachenko

“…The article analyzes the main types of oral and written communication on the material of different functional styles of the Ukrainian language. The research methodology consists of both the main methods of functional stylistics and its partial and concrete-practical methods, namely: functional, complex, semantic, comparative methods, multifaceted analysis and the method of direct observation. …”
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Enhancing bioactive profiles of elderberry juice through yeast fermentation: a pathway to low-sugar functional beverages by Amir Shazad, Ali Zein Alabiden Tlais, Davide Gottardi, Pasquale Filannino, Francesca Patrignani, Rosalba Lanciotti, Marco Gobbetti, Raffaella Di Cagno

“…In response to the growing need for functional beverages, this study aimed to harness yeast metabolism to optimize elderberry juice fermentation, targeting sugar reduction and enrichment of bioactive compounds with enhanced functional properties. …”
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Influence of environmental exposures on T follicular helper cell function and implications on immunity: a comparison of Bangladeshi and American children by Dana M. Van Fossen, Hyunjae Cho, Lisa E. Wagar, Jennie Z. Ma, Julie Parsonnet, Rashidul Haque, Mark M. Davis, William A. Petri

“…ABSTRACT T follicular helper (Tfh) cells are crucial for B cell activation and subsequent antibody production. This functionality is influenced by surface markers such as CD40L, a costimulatory factor which promotes B cell activation, and CD57, which is a well-known marker of senescence. …”
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Multimodal Fusion Framework for Urban functional zone change detection using Remote Sensing and Social Sensing Data by B. Fang, B. Fang, B. Fang, B. Fang, X. Chen, X. Chen, X. Chen, X. Chen, H. Chen, H. Chen, Z. Xiang, Z. Xiang, B. Hu, B. Hu, Z. Hu, Z. Hu, Z. Hu, Z. Hu, W. Tu, W. Tu, W. Tu, W. Tu

“…For the RS-branch, RS imagery provides detailed spatial information about urban transformations; for the MP-branch, MP data as a typical social sensing data captures temporal patterns in human mobility, offering insights into functional shifts in urban spaces. By fusing these two complementary modalities, our approach allows for a more nuanced detection of urban functional zone changes. …”
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Development of Human Mast Cells from Hematopoietic Stem Cells within a 3D Collagen Matrix: Effect of Stem Cell Media on Mast Cell Generation by Tahereh Derakhshan, Rudra Bhowmick, Jerry W. Ritchey, Heather Gappa-Fahlenkamp

“…This work demonstrates the development of functional MCs within a 3D collagen matrix using a stem cell media that supports fibroblast and ECs.…”
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Isoliensinine Induces Ferroptosis in Urothelial Carcinoma Cells via the PI3K/AKT/HIF-1α Axis: Molecular Evidence from Next-Generation Sequencing by Yun-Chen Li, Hsuan-En Huang, Chia-Ying Yu, Ya-Chuan Chang, Shu-Yu Lin, Shao-Chuan Wang, Wen-Wei Sung

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Above-mJ optical parametric chirped pulse amplifier at 3 μm for laser-driven coherent soft x-ray generation beyond the water window by Pritha Dey, Lutz Ehrentraut, Johannes Tümmler, Matthias Schnürer, Stefan Eisebitt

“…Optical parametric chirped pulse amplification (OPCPA) provides an excellent platform to generate ultrashort mid-infrared pulses in the spectral window beyond the scope of traditional mode-locked lasers. …”
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Incorporation of liver chemistry score in predicting survival of liver‐involved advanced gastric cancer patients who received palliative chemotherapy by Ying Feng, Cheng Zhang, Zhijun Wu, Hui Xu, Xiaopeng Zhang, Chong Feng, Jingyi Shao, Minmin Xie, Yahui Yang, Yi Zhang, Tai Ma

“…Abstract Background Gastric cancer liver metastasis (GCLM) patients usually accompany by abnormal serum liver function tests (LFTs) more or less; however, the prognostic value of LFTs is not fully understood. …”
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Neospora caninum infection specifically suppresses the expression of a host lncRNA XR_001919077.1 to facilitate parasite propagation by modulating host cell mitochondrial function... by Shan-Shan Zhao, De-Liang Tao, Jin-Ming Chen, Ming-Yi Zhang, Xin Yang, Jun-Ke Song, Qun Liu, Guang-Hui Zhao

“…The endometrium is more vulnerable to infection by pathogenic microorganisms resulting in an increased risk of miscarriage. …”
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