Exacerbated ischemic brain damage in type 2 diabetes via methylglyoxal-mediated miR-148a-3p decline by Zhenguo Yang, Cheng Huang, Wenhui Huang, Chao Yan, Xueyi Wen, Di Hu, Hesong Xie, Kejing He, Chi Kwan Tsang, Keshen Li

“…Methods Using T2D models generated with streptozotocin plus a high-fat diet or db/db mice, and then inducing focal ischemic stroke through middle cerebral artery occlusion and reperfusion (MCAO/R), we established a diabetic stroke mouse model. …”
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Multi-Robot Navigation System Design Based on Proximal Policy Optimization Algorithm by Ching-Chang Wong, Kun-Duo Weng, Bo-Yun Yu

“…The system consists of a localization unit, an environment map unit, a path planning unit, and an environment monitoring unit, which provides functions for calculating robot coordinates, generating preselected paths, selecting optimal path combinations, robot navigation, and environment monitoring. …”
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Assessment of test-retest reproducibility by [18F]Bavarostat for PET imaging of HDAC6 by Mika Naganawa, Ming-Qiang Zheng, Jean-Dominique Gallezot, Robin Bonomi, Jiwei Gu, Hong Gao, Swanee Jacutin-Porte, Nabeel B. Nabulsi, Michel Koole, Koen Van Laere, David Matuskey, Yiyun Huang, Richard E. Carson

“…Arterial blood sampling and metabolite analysis were performed to derive the input function. The two scans were 28 ± 12 days apart (14–43 days, n = 6). …”
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Integrated meta-analysis and network pharmacology analysis: evaluation of Zhigancao decoction as treatment for diabetic cardiomyopathy by Kangshou Ji, Kangshou Ji, Meizi Han, Mingqian Yang, Qian Xu, Yan Zhang, Yan Zhang

“…Meanwhile, the utilization of ZGCD during intervention was more effective in reducing SBP, and DBP. In addition, the ZGCD showed potential in reducing the occurrence of adverse events. …”
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Preliminary evaluation of a mindfulness intervention program in women with long COVID dysautonomia symptoms by Elizabeth Vandenbogaart, Matthew Figueroa, Diana Winston, Steve Cole, Julienne Bower, Jeffrey J. Hsu

“…Nonetheless, the symptom burden in this population is very high, and more attention is needed to provide effective multi-modal clinical therapies to this population.…”
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The role of mitochondria in the ischemic-reperfusion damage of the brain in operations on aortal arch in conditions of experiment by S. M. Gramatiuk, Yu. V. Ivanova, V. I. Kravchenko, O. O. Lohvinenko

“…In environment of ischemia/reperfusion of the brain in its cells a significant disorders of mitochondrial function occur, which are demonstrated by raising of generation of the oxygen active forms, and by lowering of transmembranous mitochondrial potential and velocity of mitochondrial respiration by 40%, what is accompanied by development of lactate-acidosis. …”
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CPT1C deficiency in SF1 neurons impairs early metabolic adaptation to dietary fats, leading to obesity by A. Fosch, D.S. Pizarro, S. Zagmutt, A.C. Reguera, G. Batallé, M. Rodríguez-García, J. García-Chica, O. Freire-Agulleiro, C. Miralpeix, P. Zizzari, D. Serra, L. Herrero, M. López, D. Cota, R. Rodríguez-Rodríguez, N. Casals

“…After long-term HFD exposure, SF1-Cpt1c-KO mice are more prone to developing obesity and glucose intolerance than control littermates, with males exhibiting a more severe phenotype. …”
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Prediction and Mapping of Soil Total Nitrogen Using GF-5 Image Based on Machine Learning Optimization Modeling by LIU Liqi, WEI Guangyuan, ZHOU Ping

“…The results revealed that 86.1% of the land in the Jian Sanjiang study area had a total nitrogen content of more than 2.0 g/kg, primarily concentrated in first and second-grade plots, while third and fourth-grade plots accounted for only 11.83% of the total area. …”
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Adenoviral-vectored neoantigen vaccine augments hyperexpanded CD8+ T cell control of tumor challenge in mice by David Li, Gabriel Dagotto, Alessandro Colarusso, Robert C Patio, Tochi Anioke, Victoria Giffin, Ruoran Guan, Trisha Anand, Esther Mbiwan, Malika Aid, Dan Barouch

“…However, Ad26.VP22.7Epi induced CD8+ T cells showed more upregulation of T cell maturation, activation, and Th1 pathways compared with peptide vaccine induced CD8+ T cells, suggesting improved functional T cell quality. …”
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Advances on whole genome sequencing in Triticeae by KUANG Liuhui, LI Qi, ZHANG Guoping

“…With the rapid development of third-generation long read sequencing technologies and assembly algorithms designed for complex genomes, and also the falling cost of genome sequencing in recent years, more and more Triticeae species have been successfully sequenced. …”
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A comparative analysis of syntactic complexity in argumentative essays from rhetorical perspective: ChatGPT vs. English native speakers. by Wenlong Liu, Xianming Liu

“…Additionally, ChatGPT's syntactic complexity was characterized by lower variability across multiple measures, indicating a more uniform and formulaic output. These findings underscore the differences between ChatGPT and native speakers in syntactic complexity and rhetorical functions in argumentative essays, therefore contributing to our understanding of ChatGPT's argumentative writing performance and providing valuable insights for ChatGPT integration into writing instruction.…”
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THE FIGHT AGAINST FRAUD IN THE EUROPEAN UNION by Mihaela Iuliana DUMITRU, Diana Elena BRINZA

“…The totality of these actions is more and more extensive, given that the access to the Community financial support is currently facilitated, as a result of the particular conditions generated by the pandemic. …”
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Weighted single-step genome-wide association study identified genomic regions and candidate genes for growth and reproductive traits in Wenchang chicken by Ranran Zhu, Yu Zhang, Yuxiang Jiang, Zihan Xu, Yurong Tai, Ziyi Lian, Zhandeng Li, Xiuping Wang, Na Luo, Guiping Zhao, Xuemei Deng

“…LDB2 was proposed as a strong candidate gene due to its significant function and high consistency with other studies regarding various carcass traits in chickens. …”
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A meta-analysis of epigenome-wide association studies of ultra-processed food consumption with DNA methylation in European children by Joana Llauradó-Pont, Nikos Stratakis, Giovanni Fiorito, Evangelos Handakas, Alexander Neumann, Henrique Barros, Anne Lise Brantsæter, Kiara Chang, Leda Chatzi, Janine F. Felix, Regina Grazuleviciene, Vincent W. V. Jaddoe, Marianna Karachaliou, Marion Lecorguillé, Carla Lopes, Christopher Millett, Rosemary R. C. McEachan, Eleni Papadopoulou, Remy Slama, Eszter P. Vamos, Paolo Vineis, Martine Vrijheid, John Wright, Trudy Voortman, Mariona Bustamante, Oliver Robinson, Camille Lassale

“…Methods We conducted a meta-analysis of epigenome-wide association studies (EWAS) from a total of 3152 children aged 5–11 years from four European studies (HELIX, Generation XXI, ALSPAC, and Generation R). UPF consumption was defined applying the Nova food classification system (group 4), and DNA methylation was measured in blood with Illumina Infinium Methylation arrays. …”
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Telemonitoring for Chronic Heart Failure: Narrative Review of the 20-Year Journey From Concept to Standard Care in Germany by Sebastian Spethmann, Gerhard Hindricks, Kerstin Koehler, Stefan Stoerk, Christiane E Angermann, Michael Böhm, Birgit Assmus, Sebastian Winkler, Martin Möckel, Mirja Mittermaier, Monika Lelgemann, Daniel Reuter, Ralph Bosch, Alexander Albrecht, Stephan von Haehling, Thomas M Helms, Stefan Sack, Tarek Bekfani, Jan Wolfgang Gröschel, Magdalena Koehler, Christoph Melzer, Jan Wintrich, Bettina Zippel-Schultz, Georg Ertl, Claus Vogelmeier, Nikolaos Dagres, Jasmin Zernikow, Friedrich Koehler

“…Years of public funding in Germany have generated evidence that remote patient management improves outcomes for patients with CHF, such as quality of life, and reduces hospital admissions. …”
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Perspectives and Experiences With Large Language Models in Health Care: Survey Study by Jennifer Sumner, Yuchen Wang, Si Ying Tan, Emily Hwee Hoon Chew, Alexander Wenjun Yip

“…While 75% (470/624) agreed that the user experience was positive, 46% (294/624) found the generated content unhelpful. Regression analysis showed that the experience with LLMs is more likely to be positive if the user is male (odds ratio [OR] 1.62, CI 1.06-2.48), and increasing age was associated with a reduced likelihood of reporting LLM output as useful (OR 0.98, CI 0.96-0.99). …”
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Embedding electronic patient-reported outcome measures into routine care for patients with stage III MELanoma (ePROMs-MEL): protocol for a prospective, longitudinal, mixed-methods... by Serigne Lo, Andrew Spillane, Donna Milne, Robyn Saw, Mbathio Dieng, Iris Bartula, Rachael Morton, Frances Boyle, Julia Lai-Kwon, Kathy Dempsey, Craig Lawn, Thomas Pennington, Skye Dong, Linda Seaman, Dina Saks, Jake Robert Thompson

“…Introduction The benefits of patient-reported feedback, using questionnaires that allow patients to report how they feel and function without any interpretation from healthcare professionals, are well established. …”
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Use of relative Patlak plot Ki′ images as an alternative to standard Patlak plot Ki images in clinical practice by Masatoyo Nakajo, Hirofumi Kawakami, Yutaro Kiyao, Mitsuho Hirahara, Akie Katsuki, Atushi Tani, Yukari Eizuru, Koji Takumi, Kiyohisa Kamimura, Fumiko Kanzaki, Takashi Yoshiura

“…Standard Patlak Ki imaging requires prolonged dynamic acquisition and full arterial input function (IF), limiting clinical feasibility. The relative Patlak plot omits the early-phase IF and focuses on the linear phase of tracer kinetics using only late dynamic data and a partially sampled IF. …”
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Intranasal application of a bifunctional pertactin-RTX fusion antigen elicits protection of mouse airway mucosa against Bordetella pertussis colonization by Carlos Espinosa-Vinals, Jana Holubova, Ondrej Stanek, Radim Osicka, Jiri Masin, Fresia Esther Arellano Herencia, Peter Sebo

“…Fusion to the N-terminus of an RTX908 antigen derived from CyaA enabled an accelerated folding of the pertactin passenger domain (rPrn) in function of calcium loading of the RTX908 moiety and conferred on the rPrn-RTX908 fusion antigen a superior capacity to induce functional anti-Prn IgG antibodies. …”
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ON POTENTIAL REPRESENTATIONS OF THE DISTRIBUTION LAW OF RARE STRONGEST EARTHQUAKES by M. V. Rodkin, V. F. Pisarenko, Ngo Thi Lu, T. A. Rukavishnikova

“…Moreover they testify also that the 'bend-down' is described by the finite distribution law, i.e. the bend-down occurs more efficiently than it is envisaged in the commonly used model developed by Y. …”
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