Specific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African Trypanosomiasis. by Juan D Unciti-Broceta, José L Arias, José Maceira, Miguel Soriano, Matilde Ortiz-González, José Hernández-Quero, Manuel Muñóz-Torres, Harry P de Koning, Stefan Magez, José A Garcia-Salcedo

“…Current therapies are characterized by high drug toxicity and increasing drug resistance mainly associated with loss-of-function mutations in the transporters involved in drug import. …”
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Strategies for choice of antiretroviral therapy in patients with HIV infection and concomitant cardiovascular disease: A review by Vasily I. Shakhgildyan, Simon T. Matskeplishvili

“…Comorbidity is gradually becoming one of the main drivers for premature mortality in HIV patients: in Russia, from 2007 to 2022, mortality rates in HIV patients not related to opportunistic infections increased more than twofold. People living with HIV have all the common cardiovascular risk factors, moreover, special attention should be paid to kidney function, since its impact on cardiovascular disease (CVD) risk is frequently underestimated. …”
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Seeking Optimal Region-Of-Interest (ROI) Single-Value Summary Measures for fMRI Studies in Imaging Genetics. by Yunxia Tong, Qiang Chen, Thomas E Nichols, Roberta Rasetti, Joseph H Callicott, Karen F Berman, Daniel R Weinberger, Venkata S Mattay

“…Our results show that four of these measures, particularly those that represent values from the top most-activated voxels within an ROI are more powerful at reliably detecting group differences and generating greater effect sizes than the others.…”
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Campus risk detection using the S-YOLOv10-SIC network and a self-calibrated illumination algorithm by Qiang Zhao, Sha Liu, Shihao Zhang, Baijuan Wang

“…The experimental results show that compared with the original YOLOv10 network, the classification loss of the model generated by the improved algorithm is reduced by about 20%, the feature point loss is reduced by about 16%, and the Parameters, Gradients and GFLOPs are reduced by more than 80%. …”
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Age-related changes in Kv4/Shal and Kv1/Shaker expression in Drosophila and a role for reactive oxygen species. by Maximiliano J Vallejos, Abdunaser Eadaim, Eu-Teum Hahm, Susan Tsunoda

“…We show that Kv4/Shal protein levels decline sharply from 3 days to 10 days, then more gradually from 10 to 40 days after eclosion. …”
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Attention-Based Multi-Objective Control for Morphing Aircraft by Qien Fu, Changyin Sun

“…Furthermore, a multi-phase pseudospectral method is derived to discretize the auxiliary problem and formulate the corresponding nonlinear programming problem, where open loop optimal solutions of the multi-task flight mission are generated. Finally, a learning-based feedback controller is established using data from the open loop solutions, where a temporal masked attention mechanism is developed to extract information from sequential data more efficiently. …”
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Advancing Insights into Large-Artery Stiffening in Humans Through the Application of Multi-omics by Marie-Joe Dib

“…Aging and various pathologic states impair this cushioning function, a phenomenon known as large-artery stiffening (LAS). …”
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Humidity measurements in carbon dioxide with Sensirion SHT85 humidity sensors under simulated Martian atmospheric conditions by A. Lorek, S. P. Garland

“…However, the SHT75 sensors from Sensirion used at that time are no longer in production and have been replaced by a new generation of sensors: SHT85. The SHT85 sensors are more precise than their predecessors, have a new sensor chip, and feature a PTFE membrane over the humidity-sensitive layer to protect the sensor from dust and liquids. …”
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The Influence of the working fluid and Regenerator material on the Performance of the types Gamma Stirling Engine by yahya abbas, Ali A. F. Al-Hamadani

“…The engine's most notable features are minimal noise, vibration, and pollution, as well as its capacity to function with any external heat source, including biomass, solar energy, and industrial waste. …”
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Comunicare la Malattia Renale Cronica by Rosa Maria De Santo

“…Eady who discovered albumin in his urine at age of nine years, and subsequently received dialysis and a transplant for more than 50 years and at the same time developed a successful academic career as dermatologist. …”
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Implementing self-healing N-policy queueing models and their impact on IoT design applications by B. Janani, K. Ambika, S. Jegan

“…Additionally, we provide explicit expressions for the transient probabilities of the model, employing generating function methodology and Laplace transform techniques. …”
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An online communicative translation assessment model in an Indonesian EFL translation class: Students’ perceptions by Soni Tantan Tandiana, Fuad Abdullah, Dede Anwar, Emmas Maspupah

“…The findings revealed that OCTAM provided students with an effective translation assessment model, coped with their limited English vocabulary, guided them to focus on knowledge of form, function, and meaning of both source and target texts, offered them a more contextual translation test, raised their awareness of translating as a meaning-making practice, facilitated them to correct grammatical errors, created a less anxious test atmosphere, and generated their multimodal communicative competence. …”
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Fracture Initiation in Aluminum Alloys Under Multiaxial Loading at Various Low Strain Rates by Mehmet Haskul, Eray Arslan

“…Among the considered fitting functions, an exponential function was selected as it provided the most accurate relation between the equivalent plastic strain at fracture and the corresponding stress state across different strain rates. …”
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Extended Framework for Preventive Maintenance Planning: Risk and Behaviour Analysis of a Proposed Optimization Model by Pablo Viveros, Marco Espinoza, Rodrigo Mena, Fredy Kristjanpoller

“…The proposed optimization model is formulated under a mixed integer linear programming (MILP) paradigm and its objective function seeks to minimize the unavailability of the system associated with the execution times of the activities developed, generating different experimental cases, and varying the start time scheduling under a tolerance factor from 0% up to a maximum of 25% for advance or delay. …”
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Triple‐Stimuli Responsive Soft Robots with Photo‐Programmable Ferriferous Oxide Particle Patterns by Siwei Hu, Kexing Li, Weijia Nong, Zhong‐Wen Liu, Zhao‐Tie Liu, Yanhu Zhan, Jinqiang Jiang, Peng Yang, Guo Li

“…Two processes, photo‐reduction of Fe3+ to Fe2+ ions and the hydrolytic reaction of the two ions, are sequentially combined to in situ generate magnetic Fe3O4 particles. Spatiotemporal control of UV light irradiation determines the Fe3+/Fe2+ ratio and, therefore the amount of generated Fe3O4 nanoparticles that decide magnetic field, NIR light, and moisture responsive actuating functionalities. …”
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Stock Price Pumping and Dumping Manipulation Detection Using Deep Learning Methods in Tehran Stock Exchange by meysam amiri, moslem peymany, Mohammad Ali Dehghan Dehnavi, Reza Jahanbin

“…In the following, by using the adversarial generative network, misbalancing of data has been solved, and by using multi-layer perceptron neural network models, recurrent neural network, long-short-term memory neural network, and radial basis function network, price manipulation has been detected. …”
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A New Cipher Based on Feistel Structure and Chaotic Maps by Al-Bahrani et al.

“…The proposed cipher operates on more than 500 bytes (4000-bit) readable text blocks by six round computing. …”
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Assessing the potential impact of transmission during prolonged viral shedding on the effect of lockdown relaxation on COVID-19. by Burcu Tepekule, Anthony Hauser, Viacheslav N Kachalov, Sara Andresen, Thomas Scheier, Peter W Schreiber, Huldrych F Günthard, Roger D Kouyos

“…A key parameter in epidemiological modeling which characterizes the spread of an infectious disease is the generation time, or more generally the distribution of infectiousness as a function of time since infection. …”
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IMPACTO EN LOS PROCESOS SOCIALES Y DE COMUNICACIONES EN UNA ENTIDAD ONCOLÓGICA COLOMBIANA by GELLY GERALDINE ÁLVAREZ SUÁREZ, EVER ÁNGEL FUENTES ROJAS, ANDERSON STIWAR MURCIA GARCÍA

“…Oncological entities aim at training, prevention and education programs on cancer-related issues; the Social andCommunications areas are fundamental to achieve this objective, since it exploits each function around society to thuspotentiate strategies that can be dissemination, approach with family and patients, in such a way that the exchange ofinformation on topics is promoted of health, paying greater attention to the care, protection and implementation ofhealthy lifestyles, given the above, the need to incorporate different methodologies that can standardize the processesthat are carried out has been generated, resulting in opportunities for improvement and effectiveness. …”
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Energetische upgrading van Nederlandse Wederopbouw flats by Frits Schultheiss

“…The new industrial overcladding repairs defects in the old building envelope. Functionally, this means better wheelchair accessibility, better separation between public and private and more spacious balconies for increased living comfort. …”
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