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1381
A Thorough Navigation of miRNA's Blueprint in Crafting Cardiovascular Fate
Published 2024-11-01“…A variety of state‐of‐the‐art technologies have aided researchers in discovering, profiling, and analyzing miRNAs, including microarray analysis, next‐generation sequencing, and others. Conclusion Developing new diagnostics and therapeutic approaches is becoming more feasible as researchers refine their understanding of miRNA function. …”
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1382
Adipocyte-expressed SIRT3 manipulates carnitine pool to orchestrate metabolic reprogramming and polarization of macrophages
Published 2025-05-01“…The deacetylase Sirtuin 3 (SIRT3) participates in inflammatory responses via regulating mitochondrial function and FAO. Herein, an AT-specific SIRT3 overexpression mice model (AT-SIRT3OE) was generated using adeno-associated virus transduction. …”
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1383
Research on acoustic emission characteristics and mechanical properties of shale under uniaxial and conventional triaxial compression
Published 2025-04-01“…In the residual stage, the AE signals generated under low confining pressure are more than those under high confining pressure. …”
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1384
Heterogeneous foraging swarms can be better
Published 2025-01-01“…IntroductionInspired by natural phenomena, generations of researchers have been investigating how a swarm of robots can act coherently and purposefully, when individual robots can only sense and communicate with nearby peers, with no means of global communications and coordination. …”
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1385
SUMO modification of a heterochromatin histone demethylase JMJD2A enables viral gene transactivation and viral replication.
Published 2017-02-01“…These finding suggest that SUMO-2/3 modification plays an essential role in the epigenetic regulatory function of JMJD2A. Consistently, hierarchical clustering analysis of RNA-seq data showed that a SUMO-deficient mutant of JMJD2A was more closely related to JMJD2A knockdown than to wild-type. …”
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1386
Human cardiac tissues produce lower contractile stress and exhibit slower cross-bridge cycling in type 2 diabetes
Published 2025-07-01“…Results Diabetic trabeculae generated 20% lower active stress and had 16% lower cross-bridge stiffness on average. …”
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1387
Monitoring Serum Bisoprolol Concentrations in Patients With Heart Failure With Reduced Ejection Fraction: Results of a Pilot Study From Routine Health Care
Published 2025-06-01“…These patients may be more prone to overdose with bisoprolol.…”
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1388
Effect of Strain Path on Retained Austenite Transformation Rates and Material Ductility in Transformation-Induced Plasticity-Assisted Advanced High-Strength Steel
Published 2025-02-01“…The retained austenite (RA) levels were measured, as a function of the plastic strain, using electron backscatter diffraction (EBSD). …”
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1389
Numerical Simulation Study of Coaxial Bubble Coalescence Based on VOF Method
Published 2025-06-01“…The bubble coalescence kernel function is one of the main kernel functions of PBM, which is used to describe the probability that two or more bubbles will coalesce into a larger bubble during collision, and its accuracy directly affects the study of bubble kinetic behavior and the prediction of thermal-hydraulic performance under the Euler-Euler frameworks. …”
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1390
A Quaternary Sedimentary Ancient DNA (<i>sed</i>aDNA) Record of Fungal–Terrestrial Ecosystem Dynamics in a Tropical Biodiversity Hotspot (Lake Towuti, Sulawesi, Indonesia)
Published 2025-04-01“…Our study showed that <i>sed</i>aDNA metabarcoding paired with the analysis of geochemical parameters yielded plausible insights into fungal-plant-soil interactions, and inferred changes in the paleohydrology and catchment evolution of tropical Lake Towuti, spanning more than one Myr of deposition.…”
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1391
Tremor and its duration‐amplitude distribution at Popocatépetl volcano, Mexico
Published 2016-09-01“…Abstract The duration‐amplitude distribution was calculated for the tremor observed at Popocatépetl volcano during episodes of activity in 2000 and 2012–2014. An exponential function was used to obtain a good fit for the duration‐amplitude distribution, and the source of volcanic tremor is probably generated by the transportation of magmatic fluids and its coupling with the host rock within the volcanic conduit. …”
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1393
Management approach matters: meeting seagrass recovery and carbon mitigation goals
Published 2025-05-01“…Abstract Seagrass habitats support biodiversity, improve water quality, protect coastlines, and sequester carbon, among other essential ecosystem functions, yet they are declining worldwide due to human activity. …”
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1394
Use ATCCfinder to identify commercially available American Type Culture Collection strains based on sequence queries
Published 2025-08-01“…The algorithm generates databases of the four ATCC data types: strain-specific genome assembly sequence data (sequence), information about how each strain was collected (metadata, catalogue), and structural/functional information about genome assemblies (annotation). …”
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1395
Resectograms: Planning liver surgery with real-time occlusion-free visualization of virtual resections
Published 2025-01-01“…To further improve functionality, we explored three flattening methods: fixed-shape, Least Squares Conformal Maps, and As-Rigid-As-Possible, to generate these 2D views. …”
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1396
Mass-Based Hybrid Nanofluid Model for Thermal Radiation Analysis of MHD Flow over a Wedge Embedded in Porous Medium
Published 2024-01-01“…Conversely, when the moving wedge parameter’s value exceeds 1, the velocity of the hybrid nanofluid decreases. The shape factor is more effective in the temperature profile for developed inputs of heat absorption/generation parameter. …”
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1397
Payload- and Energy-Aware Tactical Allocation Loop-Based Path-Planning Algorithm for Urban Fumigation Robots
Published 2025-03-01“…Such improvements can diminish operator exposure, extend mission durations, and foster safer, more efficient urban pest control.…”
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1398
ROS‐Driven Nanoventilator for MRSA‐Induced Acute Lung Injury Treatment via In Situ Oxygen Supply, Anti‐Inflammation and Immunomodulation
Published 2025-05-01“…This nanocapsule can effectively improve the stability and loading rate of enzymes, and enhance their enzyme cascade efficiency, thereby efficiently consuming •O2− and H2O2 to generate O2 in situ and reducing ROS level. More interestingly, in situ O2 supply can effectively relieve lung hypoxia to reduce HIF‐1α expression and balance the number of M1/M2 macrophages to reduce the levels of TNF‐α, IL‐1β and IL‐6, thereby alleviating the inflammatory response. …”
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1399
Design and Application of ATS Dispatch Path Search Method
Published 2023-02-01“…The method has been applied to Changsha urban rail transit Line 3 and Line 4, Wuxi urban rail transit Line 4, to support plan editing and train scheduling, and achieves good results, such as the generation time of station map can reduce over 70%,incidental jamming of the route trigger is eliminated when there are more trains,and route files can be generated automatically within minutes (original manual generation took several days).…”
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1400
Sustained tsunami-wave excitations and oscillations in the lagoon of a semi-enclosed atoll island in the South China Sea
Published 2025-12-01“…Particularly, the plateau-shape shallow water area in the lagoon functions as a basin that traps waves to oscillate for more than 30 h, generating multiple amplified waves (∼1.5 m) in the lagoon and strong currents (>5 m/s) prevalence within shallow water area (<12 m). …”
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