Revisiting the Middle Molecule Hypothesis of Uremic Toxicity: A Systematic Review of Beta 2 Microglobulin Population Kinetics and Large Scale Modeling of Hemodialysis Trials In Sil... by Maria Eleni Roumelioti, Thomas Nolin, Mark L Unruh, Christos Argyropoulos

“…A quantitative description of the relative importance of factors determining β2M concentrations among patients with impaired kidney function is currently lacking.<h4>Methods</h4>Herein we undertook a systematic review of existing studies reporting patient level data concerning generation, elimination and distribution of β2M in order to develop a population model of β2M kinetics. …”
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Photoinduced ferroelectric phase transition triggering photocatalytic water splitting by Jun Wen, Zhi-rui Luo, Lin-can Fang, Wen-xian Chen, Gui-lin Zhuang

“…This study employs real-time time-dependent density functional theory (rt-TDDFT) and first-principle calculations to propose a “one stone, two birds” strategy: light induces ferroelectric phase transitions and triggers PWS on monolayer Hf2Ge2S6. …”
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A comparative framework to develop transferable species distribution models for animal telemetry data by Joshua A. Cullen, Camila Domit, Margaret M. Lamont, Christopher D. Marshall, Armando J. B. Santos, Christopher R. Sasso, Mehsin Al Ansi, Kristen M. Hart, Mariana M. P. B. Fuentes

“…The comparative framework presented here may be applied to a variety of species, ecological datasets (e.g., presence‐only, presence‐absence, mark‐recapture), and modeling frameworks (e.g., resource selection functions, step selection functions, occupancy models) to generate transferable predictions of species–habitat associations. …”
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Improving the quantification of peak concentrations for air quality sensors via data weighting by C. Frischmon, J. Silberstein, A. Guth, E. Mattson, J. Porter, M. Hannigan

“…Leveraging two different weighting functions, a sigmoidal and a piecewise weighting regime, we explored the impacts of the base model choice (multilinear regression, MLR, vs. random forest, RF, models), the sensitivity of weighting functions, and the ability of data weighting to improve high-concentration pollution measurements. …”
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Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study. by Christopher S Carlson, Tara C Matise, Kari E North, Christopher A Haiman, Megan D Fesinmeyer, Steven Buyske, Fredrick R Schumacher, Ulrike Peters, Nora Franceschini, Marylyn D Ritchie, David J Duggan, Kylee L Spencer, Logan Dumitrescu, Charles B Eaton, Fridtjof Thomas, Alicia Young, Cara Carty, Gerardo Heiss, Loic Le Marchand, Dana C Crawford, Lucia A Hindorff, Charles L Kooperberg, PAGE Consortium

“…Models based directly on functional variation may generalize more robustly, but the identification of functional variants remains challenging.…”
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Novel MAGT1 Mutation Found in the First Chinese XMEN in Hong Kong by Elaine Yuen Ling Au, Edmund Kwok Kwan Tung, Ricky Wai Ki Ip, Philip Hei Li

“…In recent years, with the advances of molecular diagnostics, more and more patients have been reclassified with more defined entities after their genetic causes were found. …”
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Optimal Path Choice in Railway Passenger Travel Network Based on Residual Train Capacity by Fei Dou, Kai Yan, Yakun Huang, Li Wang, Limin Jia

“…Passenger’s optimal path choice is one of the prominent research topics in the field of railway passenger transport organization. More and more different train types are available, increasing path choices from departure to destination for travelers are unstoppable. …”
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RECURRENT DEPRESSIVE DISORDER,TYPE 2 DIABETES MELLITUSAND OXIDATIVE STRESS by P. Marinov, Y. Petkov

“…Because ROS is an essential mediator for the activation of pro-inflammatory signalling pathways, obesity and hyperglycaemia-induced ROS production may favour the induction of M1-like pro-inflammatory macrophages during the onset and progression of diabetes. By generating more reactive oxygen species (ROS) and upregulating markers of chronic inflammation, hyperglycaemia can lead to vascular dysfunction. …”
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Mechanical Behavior and Energy Evolution of Sandstone considering Slenderness Ratio Effect by Bibo Dai, Xingdong Zhao, Shuwen Zhang, Qian Kang, Zhonghua Zhu

“…When the slenderness ratio, D, is lower than 1.5, complex failures and multiple shear planes are formed, while simple failures and single shear planes are generated at D larger than 1.5. Besides, the AE ringing counts are more obvious with a higher slenderness ratio, D, at the initial compression stage due to the greater body volume and more defects in the sandstone. …”
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The “What” of Athletes’ Goal Pursuit and Its Relationships to Goal-Related Processes and Well- and Ill-Being by Natalia Martínez-González, Francisco L. Atienza, Joan L. Duda, Isabel Balaguer

“…The results showed that intrinsic goals, assessed in an open-ended format, were more heterogeneous in terms of content, and more common among athletes than extrinsic goals. …”
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Constructing a web recommender system using web usage mining and user’s profiles by T. Mombeini, A. Harounabadi, J. Rezaeian Sheshdeh

“…Date is of importance since it is more possible for users to request new pages more than old ones and old pages are less probable to be viewed, as users mostly look for new information. …”
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Deformation anisotropy and lamellar α re-orientation of TC17 alloy under the different slip modes of HCP structure by Cong Li, Jiao Luo

“…Therein, the variation of the rotation factor with tilt angle conforms to the quadratic function, reaching a maximum value around 45°. When the rotation factor is small, the ratio of (01–11) [1–210] slip system with small Burgers vector at the phase boundary is large, the rotation tendency is poor, and the intragranular dislocation slip replaces the grain rotation as the strain accommodation mechanism, the lamella is more prone to globularization. …”
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Cardiac disease diagnosis based on GAN in case of missing data. by Xing Chen, Na Zhang, Xiaohui Yang, Chunyan Wang, Qi Na, Tianyun Luan, Wendi Zhu, Chenjie Zhang, Chao Yang

“…Furthermore, the distribution deviation between the generated data and the real data is integrated into the loss function of the generative adversarial networks, improving their training stability and ensuring consistency between the generated data and the real data distribution. …”
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Infection of Enterocytozoon bieneusi in a Patient with Long-Term Immunosuppression after Liver Transplantation: A Case Report and Literature Review by Xiaohua Hong, Lei Zeng, Qiong Li, Tiankai Yang, Jing Zhou, Huayou Li, Yunchao Mo, Shaoyi Zhuo, Jiudong Ma, Jingyue Cai, Caipeng Xie

“…Case Presentation: In this article, we reported a case of persistent chronic diarrhea and renal failure due to E.b infection after liver transplantation, which was definitively diagnosed using metagenomic next-generation sequencing (mNGS). Short course of albendazole was applied to the patient, resulting in rapid resolution of clinical symptoms and recovery of renal function. …”
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Product Line Diversification as a Growth Strategy in the E-Commerce Market: From a Startup to a Multi-Million Dollar Company by Vladimir Kochnev

“…With growth needs continuing to rise, more and more E-commerce businesses are becoming prone to adopt product line diversification as a strategic option to enhance their growth, expand their market reach and revenue generation. …”
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A 3D Most Vulnerable Path Search Method for Physical Protection Systems Based on the EASI Model by Aiguo Li, Yanfeng Deng

“…The search efficiency is improved by restricting the intermediate points and the angle between the start and target points and improving the heuristic function. The improved algorithms are simulated and compared, and the results show that the paths generated by the improved algorithms are more reasonable, and the algorithms consume less time and have shorter path lengths.…”
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Intelligent design and implementation of blockchain and Internet of things–based traffic system by Qilei Ren, Ka Lok Man, Muqing Li, Bingjie Gao, Jieming Ma

“…In real-life traffic scenarios, it may generate more complex system and data security issues, which will be elaborated and analyzed at the end of this article. …”
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Biomedical applications of organoids derived from the digestive system by Zhensheng Xu, Zhongwen Lei, Qiuhua Cheng, Yuanhui Gao, Yang Xiang

“…This technology not only better recapitulates cell-to-cell interactions, extracellular matrix (ECM) microenvironment, and organ-specific physiological functions but also more closely mimics the human physiological state in vitro. …”
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A Novel Exploration Stage Approach to Improve Crayfish Optimization Algorithm: Solution to Real-World Engineering Design Problems by Harun Gezici

“…It is deprived of a stochastic variable and is not able to generate an applicable balance between exploration and exploitation. …”
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Phase Current Equalization Method of IPMSM-Based on-Board Boost Converter for Electric Vehicles by Yunkyung Hwang, Jaehong Kim, Minhyeok Lee, Juwon Choi, Kwanghee Nam

“…In this study, the complete IPMSM inductance model is utilized to obtain an analytical representation of the current ripple as a function of the switching duty and rotor angle. Based on this, the maximum charging current is estimated and the maximum charging power is also derived as a function of the rotor angle. …”
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