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Adaptation of the REINVENT neural network architecture to generate potential HIV-1 entry inhibitors
Published 2024-09-01“…To accelerate the learning of the neural network in the modified version of the REINVENT model, the AutoDock-Vina-GPU-2.1 docking program was used, and to clarify the results of its work, the procedure for revaluing the affinity of compounds to the target using the RFScore-4 evaluation function was used.Results. Using a modified version of the REINVENT model, more than 60,000 compounds were obtained, of which about 52,000 molecules have a binding energy value to the HIV-1 gp120 protein comparable to the value calculated for the HIV-1 inhibitor NBD-14204, used in calculations as a positive control. …”
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Impact of Generation Rate of Speech Imagery on Neural Activity and BCI Decoding Performance: A fNIRS Study
Published 2025-01-01“…Additionally, the differences in neural activities between the “yes” and “no” speech imagery tasks became more pronounced as the generation rate increased, leading to an improvement in classification performance from 62.81% to 65.78%, and ultimately to 67.50%. …”
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New Lifetime Alpha Power Exponential Weibull Distribution: Structure and Properties
Published 2025-07-01“…The cumulative, probability density, survival, hazard functions, and statistical properties of the proposed new model distribution were discussed and studied such as quantile function, moment about origin, moment generating function, Skewness, Kurtosis, factorial moments generating function, and characteristic function. …”
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Deus ex nomine: Once more on the language myth and naïve religion
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The Art of Generative Narrativity
Published 2024-12-01“…It sometimes leads to generative experiments with non-verbal forms or events that have the potential to incite narratives through the audience’s experience of the works’ functionalities, backgrounds, and contexts. …”
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Super Virus Machines: Faster Virus Transmission, More Efficiency Using Superchannels
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Multitasking muscle: engineering iPSC-derived myogenic progenitors to do more
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The mediating role of family functioning between childhood adversity and adult Health- related risk behaviors: a moderated mediation analysis of generational gap in Chinese migrant...
Published 2025-05-01“…This study aims to elucidate the mediating role of family functioning and explore generational differences in this relationship. …”
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SER analysis of cooperative M2M communications assisted by multiple AF relays
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SER analysis of cooperative M2M communications assisted by multiple AF relays
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Performance evaluation of photovoltaic scenario generation
Published 2025-03-01“…Despite recent theoretical advancements, effectively evaluating the performance of photovoltaic scenario generation remains a significant challenge. Existing studies predominantly rely on metrics such as mean, variance, and probability density functions for assessment. …”
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A system for generating chatbots to support learning in the field of exact sciences using generative artificial intelligence models
Published 2025-05-01“…The objectives include: analyzing the challenges and peculiarities of creating chatbots and preparing high-quality datasets; developing the structure and describing the functionality of the chatbot generation system; providing examples of creating various types of chatbots; conducting experiments to determine the effectiveness and cost of chatbot generation. …”
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