The effect of gamma radiation on the structure of graphene oxide and graphene oxide functionalized with amino-PEG by Jaqueline Jamara Souza Soares, Raynara Maria Silva Jacovone, Paulo SOUZA Santos, Márcio Henrique Zaim, Dalva Lucia Araújo Faria, Solange Kazumi Sakata

“…ABSTRACT   Covalent functionalization of graphene oxide (GO) with polyethylene glycol (PEG) has been widely used in drug delivery systems. …”
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Transcriptional landscape of small non-coding RNAs reveals diversity of categories and functions in molluscs by Songqian Huang, Kazutoshi Yoshitake, Shigeharu Kinoshita, Shuichi Asakawa

“…To unravel the small RNA (sRNA) expression patterns and genomic function in molluscs, we generated a comprehensive sRNA dataset by sRNA sequencing (sRNA-seq) of eight mollusc species. …”
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Genetic Dissection of Tissue-Specific Apolipoprotein E Function for Hypercholesterolemia and Diet-Induced Obesity. by Tobias Wagner, Alexander Bartelt, Christian Schlein, Joerg Heeren

“…Therefore we generated transgenic mice carrying homozygous floxed Apoe alleles. …”
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THYROID FUNCTION AND REPRODUCTIVE HEALTH OF TEENAGE BOYS OF MAJOR ETHNIC GROUPS IN EASTERN SIBERIA by A. V. Labygina, E. Yu. Zagarskikh, L. F. Sholokhov, A. A. Semendyaev

“…However, the teenagers Caucasians living in urban areas, the puberty and physical development delay met in 2,5-1,4 times more often (33,8-58,3 %; px2 < 0,05). Our data support a role of thyroid dysfunction in the development of reproductive disorders, and therefore timely diagnosis, treatment and recovery of thyroid function is necessary for the prevention of infertility. …”
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Functional Thyroid Organoids—Powerful Stem Cell-Derived Models in Basic and Translational Research by Meghna Parakkal Shankar, Alessandra Boggian, Daniela Aparicio-Quiñonez, Sami Djerbib, Eduardo Rios-Morris, Sabine Costagliola, Mírian Romitti

“…By utilizing pluripotent stem cells (PSCs) and adult tissue, researchers have generated organoid models suitable for dissecting the mechanisms associated with thyroid development while mimicking the genetic, functional, and inflammatory characteristics of thyroid diseases. …”
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Perineural invasion in pancreatic cancer: Current biological function in R status, prognosis, and pain by Federico Selvaggi, Elisa Bannone, Eugenia Melchiorre, Michele Diana, Roberto Cotellese, Gitana Maria Aceto

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Stable minichromosome and functional neocentromere derived from rye 7R chromosome arm by Zongxiang Tang, Qian Liu, Zijin Pan, Chang Liu, Jieran Dong, Fangpu Han, Shulan Fu

“…Abstract Background The study of newly formed centromere with stable transmission ability can provide theoretical guidance for the construction of artificial chromosomes. More neocentromeres are needed to study the mechanisms of their formation. …”
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Integrating AI in Education: An Analysis of Factors Influencing the Acceptance, Concerns, Attitudes, Competencies and Use of Generative Artificial Intelligence Among Polish Teacher... by Łukasz Tomczyk, Aleksandra Majkut

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TMT-Opsins differentially modulate medaka brain function in a context-dependent manner. by Bruno M Fontinha, Theresa Zekoll, Mariam Al-Rawi, Miguel Gallach, Florian Reithofer, Alison J Barker, Maximilian Hofbauer, Ruth M Fischer, Arndt von Haeseler, Herwig Baier, Kristin Tessmar-Raible

“…Despite their conserved widespread occurrence, the nonvisual functions of opsins are still largely enigmatic. This is even more apparent when considering the high number of opsins. …”
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Functionalization-Dependent Cytotoxicity of Silver Nanoparticles: A Comparative Study of Chlorhexidine and Metronidazole Conjugates by Karol P. Steckiewicz, Monika Dmochowska, Elżbieta Megiel, Ewelina Barcińska, Iwona Inkielewicz-Stępniak

“…AgNPs-CHL, in which silver surface functionalization was realized via nitrogen–silver interactions, induced significant ROS generation, LDH release, and necroptosis, marked by increased RIP1, RIP3, and MLKL proteins. …”
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Uncovering novel functions of the enigmatic, abundant, and active Anaerolineae in a salt marsh ecosystem by Paige E. Payne, Loren N. Knobbe, Patricia Chanton, Julian Zaugg, Behzad Mortazavi, Olivia U. Mason

“…The data revealed that the belowground salt marsh Anaerolineae in the rhizosphere are important players in carbon cycling, including degradation of simple carbon compounds and more recalcitrant plant material, such as cellulose, using a diversity of electron acceptors and represent an unexplored reservoir of novel secondary metabolites.IMPORTANCEGiven that coastal salt marshes are recognized as biogeochemical hotspots, it is fundamentally important to understand the functional role of the microbiome in this ecosystem. …”
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Cerium oxide nanoparticles in vivo distribution and transformation behavior mediate intestinal transit function by Chunli Lei, Rui Liang, Bingxu Cheng, Le Yue, Xuesong Cao, Chuanxi Wang, Zhenyu Wang, Baoshan Xing

“…Therefore, this work provides more accurate descriptions of the entire physiological process of CeO2 NPs after ingestion, spotlights their intestinal transport fate and redox functional effects, and opens up new theoretical perspectives for potential human health studies of NPs.…”
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Inactivation of antibiotic resistant bacteria by nitrogen-doped carbon quantum dots through spontaneous generation of intracellular and extracellular reactive oxygen species by Weibo Xia, Zixia Wu, Bingying Hou, Zhang Cheng, Dechuang Bi, Luya Chen, Wei Chen, Heyang Yuan, Leo H. Koole, Lei Qi

“…In in vivo studies, the N-CQDs were more efficient in treating drug-resistant bacterial keratitis and reducing corneal damage compared to the common antibiotic levofloxacin. …”
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Interfacial solar‐driven steam and electricity co‐generation using Hydrangea‐like graphene by salt‐assisted carbonization of waste polylactic acid by Huiyue Wang, Xueying Wen, Kuankuan Liu, Qiuxuan Liu, Guixin Hu, Huajian Liu, Yan She, Ran Niu, Tao Tang, Jiang Gong

“…Hence, it achieves the evaporation rate of 3.0 kg m−2 h−1 and output voltage of 0.425 V, surpassing many advanced evaporators/generators. Molecular dynamics simulation result proves that more Na+ ions are attracted by functional groups, especially –COOH/C–OH, to promote Na+ selectivity in nanochannels. …”
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REPRESENTATION OF GENERAL DIFFERENCES IN THE INTELLECTUAL NOVELS BY V. PETROV-DOMONTOVYCH by Tetyana I. Virchenko

“…Attention to generational studies is due to their significant potential, which lies in forecasting the development of society, understanding of worldviews, therapeutic functions, and more. …”
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Opinion dynamics of leaders and followers with multi-criteria influence functions for urban transport project application by Julius Selle, Rica Villarosa, Charldy Wenceslao, Dharyll Prince Abellana, Rhoda Namoco, John Kevin Padro, Lanndon Ocampo

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Optimisation of Several Estimating Functions by Multicriterial Analysis of Civil Engineering Structure in Service Stage Monitoring by Daniel LEPĂDATU, Dorina ISOPESCU, Ion RUSU, Loredana JUDELE, Gabriel SANDULACHE

“…In this paper we will present an optimization of the estimation functions of the evaluation criteria behaviour for the time monitoring of an engineering structure. …”
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Functional compounds in tropical fruit processing by-products and intrinsic factors affecting their composition: A review by María Romero-Martínez, Ricardo Andrade-Pizarro, Claudia De Paula

“…Tropical fruits, highly demanded in the food industry, generate a considerable amount of waste during processing. …”
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Counterfactual explanations of tree based ensemble models for brain disease analysis with structure function coupling by Shaolong Wei, Zhen Gao, Hongcheng Yao, Xiaoyu Qi, Mingliang Wang, Jiashuang Huang

“…Abstract Convergent evidence has suggested that the disruption of either structural connectivity (SC) or functional connectivity (FC) in the brain can lead to various neuropsychiatric disorders. …”
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Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibition by Britta Lipinski, Laura Unmuth, Paul Arras, Stefan Becker, Christina Bauer, Lars Toleikis, Simon Krah, Achim Doerner, Desislava Yanakieva, Ammelie Svea Boje, Katja Klausz, Matthias Peipp, Vanessa Siegmund, Andreas Evers, Harald Kolmar, Lukas Pekar, Stefan Zielonka

“…By engineering paratope valencies and the spatial orientation of individual paratopes within the overall design architecture, we were able to generate IL-18 mimetics displaying significantly augmented functionalities, resulting in bispecific cytokine mimetics that were more potent than IL-18 in triggering proinflammatory cytokine release. …”
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