Machine learning-based model for acute asthma exacerbation detection using routine blood parameters by Youpeng Chen, Junquan Sun, Yabang Chen, Enzhong Li, Jiancai Lu, Huanhua Tang, Yifei Xie, Jiana Zhang, Lesi Peng, Haojie Wu, Zhangkai J. Cheng, Baoqing Sun

“…Significant variables were identified through logistic regression, and 12 machine learning algorithms were used to construct diagnostic models, which were evaluated using Receiver Operating Characteristic (ROC) analysis, calibration, and Decision Curve Analysis (DCA). Results: The Generalized Linear Model Boosting combined with Random Forest (glmBoost + RF) algorithm using 14 variables achieved comparable performance (Area Under the Curve [AUC] = 0.981) to the more complex Least Absolute Shrinkage and Selection Operator combined with Random Forest (Lasso + RF) algorithm using 25 variables (AUC = 0.985). …”
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Assessing the prognostic and therapeutic value of cuproptosis-related genes in colon adenocarcinoma patients by Zhanhui Ye, Yixian Song, Mengqing Zhu, Fuying Zheng, Wenjie Qin, Wenjie Qin, Xue Li, Pei Wang, Zihua Li, Kequan Chen, Aimin Li

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CLINICAL AND IMMUNOLOGICAL CHARACTERISTICS OF DIABETES-ASSOCIATED OSTEOARTHRITIS by I. V. Shirinsky, N. Yu. Kalinovskaya, V. S. Shirinsky

“…We found that clinical manifestations of DM-associated OA were associated with increased body weight, more pronounced level of joint pains, longer duration of morning stiffness, decreased functionality of hands and large joints, impaired quality of life and more severe clinical pattern of the illness. …”
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Rehabilitation effect on psycho-emotional well-being in women with surgically treated vulvar cancer: a randomised controlled trial by Blinov V. Dmitry, Antonina G. Solopova, Elena V. Gameeva, Nazim G. Badalov, Vsevolod N. Galkin, Mikhail A. Eremushkin, Alexandra M. Stepanova, Alexander E. Ivanov, Olga S. Gridasova

“…Surgical treatment of vulvar cancer (VC) entails mental and somatic disturbances due to pain, body image changes, and sexual dysfunction, which are closely associated with impaired social functioning and reduced overall quality of life. However, the results evaluating the impact of rehabilitation programmes on various components of quality of life in these patients remain limited. …”
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Beta-adrenergic reactivity of erythrocyte membranes in various phenotypes of uncontrolled hypertension by M. A. Manukyan, A. Yu. Falkovskaya, V. F. Mordovin, I. V. Zyubanova, V. A. Lichikaki, E. I. Solonskaya, A. A. Vtorushina, S. A. Khunkhinova, I. A. Skomkina, V. V. Rudenko, T. Yu. Rebrova, E. F. Muslimova, S. A. Afanasyev

“…Aim. To assess the functional state of the sympathetic nervous system according to β-adrenergic reactivity of erythrocyte membranes (EM) in patients with refractory (rfHTN) and resistant hypertension (rHTN) in relation to target organ damage.Material and methods. …”
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Prediction of Pathologic Response in Unresectable Hepatocellular Carcinoma After Downstaging with Locoregional and Systemic Combination Therapy by Yang C, Chen Y, Sheng L, Wang Y, Zhang X, Yang Y, Ronot M, Jiang H, Song B

“…Chongtu Yang,1,2,* Yidi Chen,1,2,* Liuji Sheng,1,2 Yanshu Wang,1,2 Xiaoyun Zhang,3 Yang Yang,4 Maxime Ronot,5 Hanyu Jiang,1,2 Bin Song1,2,6 1Department of Radiology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 2Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China; 3Division of Liver Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 4Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China; 5Department of Radiology, Hôpital Beaujon (Université de Paris), Clichy, France; 6Department of Radiology, Sanya People’s Hospital, Sanya, Hainan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hanyu Jiang; Bin Song, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, People’s Republic of China, Email hanyu_jiang@foxmail.com; songlab_radiology@163.comBackground: The combination of locoregional and systemic therapy may achieve remarkable tumor response for unresectable hepatocellular carcinoma (HCC).Objective: We aimed to investigate the correlation between radiologic and pathologic responses following combination therapy, evaluate their prognostic values, and to establish a non-invasive prediction system for pathologic response.Methods: This single-center retrospective study included 112 consecutive patients with HCC who underwent locoregional and systemic combination therapy followed by liver resection or transplantation. …”
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Reliability of multi-site UK Biobank MRI brain phenotypes for the assessment of neuropsychiatric complications of SARS-CoV-2 infection: The COVID-CNS travelling heads study. by Eugene Duff, Fernando Zelaya, Fidel Alfaro Almagro, Karla L Miller, Naomi Martin, Thomas E Nichols, Bernd Taschler, Ludovica Griffanti, Christoph Arthofer, Gwenaëlle Douaud, Chaoyue Wang, Thomas W Okell, Richard A I Bethlehem, Klaus Eickel, Matthias Günther, David K Menon, Guy Williams, Bethany Facer, David J Lythgoe, Flavio Dell'Acqua, Greta K Wood, Steven C R Williams, Gavin Houston, Simon S Keller, Catherine Holden, Monika Hartmann, Lily George, Gerome Breen, Benedict D Michael, Peter Jezzard, Stephen M Smith, Edward T Bullmore, COVID-CNS Consortium

“…A multi-modal brain MRI protocol comprising sequences for T1-weighted MRI, T2-FLAIR, diffusion MRI (dMRI), resting-state functional MRI (fMRI), susceptibility-weighted imaging (swMRI), and arterial spin labelling (ASL), was defined in close approximation to prior UK Biobank (UKB) and C-MORE protocols for Siemens 3T systems. …”
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“Bagaimana Mereka Mengubahku?” (Interpretative Phenomenological Analysis tentang Rekonstruksi Identitas pada Muslimah Bercadar) by Santi Riksa Pratiwi, Nuke Martiarini

“…There are a theme about feeling, that was feeling more comfortable when using veil. Themes about behaviors, that was behaving as well as possible and inviting others, families who understanding the decision to veiled, the influence of the P ****** da'wah community is strong enough, and the environment of friends, neighbors and the general public is less supportive. …”
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The Effect of Wet and Dry Heating Process and Wheat Flour Particle Sizes on Dough Rheology and Staling of Bread by Mohammad Fazli Rad, Jafar Milani, Sepide Haghighat

“…The results of thermal analysis showed that the moist heat treatment sample with a particle size of 180 microns had the lowest enthalpy and was the best sample (p<0.05).ConclusionIn general, the use of flour with a particle size of 180 microns and moist heat treatment to improve the rheological and staling properties of bread were the best examples.…”
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Provenance-Finding of Dust Storms Using AVHRR Sensor Images of NOAA Satellite (Case Study: Southwest of Iran) by Mohammad Hossein Rezaei Moghaddam, Mojtaba Mahdian Boruojeni

“…The particles are more affected by the northwest winds and the diffusion of pollution to the southeast. …”
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MODERN CONCEPTS OF TREATING HYPERESTHESIS OF HARD TOOTH TISSUES (REVIEW OF LITERATURE) by S.P. Yarova, O.S. Genzytska, Yu.Yu. Yarov, A.A. Komlev

“…Starting from an earlier age women suffer more often than men. The generalized form of hyperesthesia is usually associated with such general causes as the functional state of the nervous system, endocrine diseases, disorders of mineral metabolism in the body. …”
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Decoding chromosomal instability insights in CRC by integrating omics and patient-derived organoids by Federica Papaccio, Manuel Cabeza-Segura, Blanca García-Micó, Francisco Gimeno-Valiente, Sheila Zúñiga-Trejos, Valentina Gambardella, María Fernanda Gutiérrez‐Bravo, Carolina Martinez‐Ciarpaglini, Pilar Rentero‐Garrido, Tania Fleitas, Susana Roselló, Juan Antonio Carbonell-Asins, Marisol Huerta, David Moro-Valdezate, Desamparados Roda, Noelia Tarazona, Manuel M. Sánchez del Pino, Andrés Cervantes, Josefa Castillo

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Prospects of IoT technology by М. V. Yadrovskaya, М. V. Porksheyan, А. А. Sinelnikov

“…In the course of the study, the IoT concept was defined, the conditions required for the existence and functioning of the technology were described, the advantages of IoT technology were generalized, information technologies interacting with this technology were specified, the tasks that require solutions for the successful and effective implementation of IoT into Russian reality were listed. …”
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Lessons learned from an fMRI-guided rTMS study on performance in a numerical Stroop task. by Lysianne Beynel, Hannah Gura, Zeynab Rezaee, Ekaete C Ekpo, Zhi-De Deng, Janet O Joseph, Paul Taylor, Bruce Luber, Sarah H Lisanby

“…However, the modeling approach revealed a robust effect of rTMS on the drift rate variable, suggesting differential processing of congruent and incongruent properties in perceptual decision-making, and more generally, illustrating that more advanced computational analysis of performance can elucidate the effects of rTMS on the brain where simpler methods may not.…”
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Lack of IFN-γ response of human uterine myometrium-derived MSCs significantly improve multiple IBD parameters compared to bone marrow MSCs: Implications for anti-TNFα-refractory pa... by Li-Tzu Wang, Hsiu-Huan Wang, Shih-Sheng Jiang, Chia-Chih Chang, Pei-Ju Hsu, Ko-Jiunn Liu, Huey-Kang Sytwu, B. Linju Yen, Men-Luh Yen

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Managers' Ability and Debt Structure: Evidence from Iran's Financial Reporting Environment by Aqil al hasoon, Seyed Abbas Hashemi, Narges Hamidian

“…In such organizations, which typically possess more robust project portfolios, short-term debt issuance serves as an additional quality indicator. …”
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Safety, Efficacy, and Feasibility of Nebulized Long-Acting Bronchodilators vs Short-Acting Bronchodilators in Hospitalized Patients With Acute Exacerbations of COPD by Rajiv Dhand, MD, Samuel Treat, MD, Jennifer Ferris, MSHS, Paul D. Terry, PhD, Tracy Walker, BA, Scott Elder, RRT, Daniel Church, RRT, Danielle Dennis, PharmD, Barbara Faircloth, PharmD, Gulsah Onar, MPH, R. Eric Heidel, PhD, Isaac Biney, MD, Martin Valdes, MD, Milind Bhagat, MBBS, Nicholas Fuerst, MD, Shannon Cusick, RN

“…Data were analyzed with parametric or nonparametric statistical tests, and generalized estimating equations with an identity link function were used to analyze differences in the two groups. …”
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Antibacterial activity of gold nanoparticles/zinc oxide (AuNP/ZnO) hybrid nanostructures by Aldrin Lalem, Jay Dulog, Jared Deve Delicana, Renzo Luis Reazo, Ryan Lumod, Rolen Brian Rivera, Noel Lito Sayson, Romnick Unabia, Gerard Dumancas, Rey Capangpangan, Mario Tan, Arnold Alguno

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Health status and risk profiles for brain aging of rural‐dwelling older adults: Data from the interdisciplinary baseline assessments in MIND‐China by Yongxiang Wang, Xiaolei Han, Xianda Zhang, Zhonglin Zhang, Lin Cong, Shi Tang, Tingting Hou, Cuicui Liu, Xiaojuan Han, Qinghua Zhang, Jianli Feng, Ling Yin, Lin Song, Yi Dong, Rui Liu, Yuanjing Li, Tiia Ngandu, Miia Kivipelto, Heather Snyder, Maria Carrillo, Jonas Persson, Laura Fratiglioni, Lenore J Launer, Jianping Jia, Yifeng Du, Chengxuan Qiu

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Development and Implementation of MyPainHub, a Web-Based Resource for People With Musculoskeletal Conditions and Their Health Care Professionals: Mixed Methods Study by Kerrie Evans, Jonathan Ko, Dragana Ceprnja, Katherine Maka, Darren Beales, Michele Sterling, Kim L Bennell, Gwendolen Jull, Paul W Hodges, Marnee J McKay, Trudy J Rebbeck

“…Patient participants identified areas for improvement such as including more specific information on preventative measures and pain relief options. …”
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