Evaluation of the clinical and cost effectiveness of intermediate care clinics for diabetes (ICCD): a multicentre cluster randomised controlled trial. by Andrew Wilson, Joseph Paul O'Hare, Ainsley Hardy, Neil Raymond, Ala Szczepura, Ric Crossman, Darrin Baines, Kamlesh Khunti, Sudhesh Kumar, Ponnusamy Saravanan, ICCD trial group

“…Community based, intermediate care clinics for diabetes (ICCDs) were considered one solution and are functioning across the UK. However, there is no randomised trial evidence for the effectiveness of such clinics.…”
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Gegen-Sangshen oral liquid and its active fractions mitigate alcoholic liver disease in mice through repairing intestinal epithelial injury and regulating gut microbiota by Shulin Wei, Mingxing Li, Long Zhao, Tiangang Wang, Ke Wu, Jiayue Yang, Yubin Liu, Yueshui Zhao, Fukuan Du, Yu Chen, Shuai Deng, Jing Shen, Zhangang Xiao, Wanping Li, Xiaobing Li, Yuhong Sun, Li Gu, Mei Wei, Zhi Li, Xu Wu

“…Notably, LGS, LGSP, and LGSF mitigated intestinal damage and maintained barrier function in ALD mice. The intestinal barrier protection function of LGS, LGSP, and LGSF was generally more obvious than that of the positive drug meltadosine. …”
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Predictive Validity of Hospital-Associated Complications of Older People Identified Using Diagnosis Procedure Combination Data From an Acute Care Hospital in Japan: Observational S... by Seigo Mitsutake, Tatsuro Ishizaki, Shohei Yano, Takumi Hirata, Kae Ito, Ko Furuta, Yoshitomo Shimazaki, Hideki Ito, Alison Mudge, Kenji Toba

“… BackgroundA composite outcome of hospital-associated complications of older people (HAC-OP; comprising functional decline, delirium, incontinence, falls, and pressure injuries) has been proposed as an outcome measure reflecting quality of acute hospital care. …”
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Comparative transcriptomic and proteomic analyses of hypoxia response in wild and cultivated tomato roots by Zhihan Zhang, Yabing Hou, Hao Yin, Song Lu, Daliang Liu, Lin Cheng, Houlin Yu, Tao Li, Yiyong Zhao

“…By analyzing the gene and protein networks of FZZ and T178 under hypoxic conditions, we inferred that T178 enhances hypoxia adaptation by forming more independent small modules and multilevel regulatory networks, whereas FZZ relies on a few large modules with limited functional diversity, resulting in weaker hypoxia tolerance. …”
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Immunological and physiological changes of exercise-released lactate on tumors: an important and new research window by Amir Hossein Ahmadi Hekmatikar, Arsham Entesari, Hossein Shirvani

“…Additionally, we have taken a more specialized approach by examining the relationship between lactate and exercise. …”
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Proteogenomic annotation of T6SS components identified in Bacteroides fragilis secretome by Natalya B. Zakharzhevskaya, Olga Yu Shagaleeva, Daria A. Kashatnikova, Daria A. Kashatnikova, Anton O. Goncharov, Anton O. Goncharov, Daria V. Evsyutina, Dmitry A. Kardonsky, Elizaveta A. Vorobeva, Artemiy S. Silantiev, Viktoria D. Kazakova, Irina V. Kolesnikova, Ivan O. Butenko, Anna A. Vanyushkina, Svetlana V. Smirnova, Andrei V. Chaplin, Andrei V. Chaplin, Boris A. Efimov, Boris A. Efimov

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Developments in Legal Education: Beyond the Primary School Model by William Twining

“…In this paper I propose to adopt a broader perspective in two respects: I shall look at some general trends and issues in the Commonwealth, that vast and amorphous network of countries that are loosely linked together by a shared imperial past, by the common law, and perhaps most important in the long run, by the English language: I shall interpret legal education more broody to include not only specialized education and vocational training in university, polytechnic and independent professional training schools, but also a whole range of activities from law in schools to continuing education of the judiciary at all levels; from formation of paraprofessionals to the development and retraining of specialists; and the vast but relatively neglected subject of legal education for non-lawyers, which ranges far beyond mis-named “service” teaching of law for businessmen, accountants , social workers and the police to include activities aimed at raising the consciousness of and providing practical tools for grass-roots activists, trade unionists and ordinary citizens to help them to understand and use and cope with law as it affects them in their daily lives and work. …”
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KIF13B C.*3163G>A SINGLE NUCLEOTIDE VARIANT ON OROPHARYNGEAL SQUAMOUS CELL CARCINOMA SUSCEPTIBILITY AND TUMOR CHARACTERISTICS by Ericka Francislaine Dias Costa, Gustavo Jacob Lourenço, Carmen Silvia Passos Lima

“…The let-7e-3p miRNA exhibited more efficient binding to the 3’-UTR of the ancestral G allele compared to the variant A allele in the FaDu (p = 0.004) and Detroit 562 (p = 0.04) cell lines. …”
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Short-term mating success in relation to fluctuating wing asymmetry in the male azure damselfly Coenagrion puella by Ken M. Mauser, Jann Baumeyer, Shahab Eshghi, Stanislav N. Gorb, Alessandro Manfrin, Carsten A. Brühl

“…In these individuals, the cell shape asymmetry was more pronounced in the distal part of the wing than in the proximal part. …”
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Identifying unimodal finite mixture models in data sets using distribution shifting – A novel approach by Paul Allen Williams, Emily K. Roberts, Quynh-Anh Nguyen, Kamal Rahmouni

“…However, if the number data distribution is represented by more than one distribution, the transformed function can result in deformation of the volume distribution and possibly the appearance of additional modes as compared to a single distribution. …”
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Welgelegen by Gerdy Alette VERSCHUURE-STUIP

“…In this study the word historic country estate is addressing the house and its garden as an ensemble and this is used for country houses (landgoederen) with a more rural function, as well as for suburban villas (buitenplaatsen) referring to houses for recreation and pleasure. …”
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The impact of tricuspid regurgitation on timing pulmonary valve replacement in ACHD patients after tetralogy of Fallot repair by Gianluca Brancaccio, Veronica Bordonaro, Matteo Trezzi, Marcello Chinali, Delia Fugallo, Carolina D'Anna, Veronica Lisignoli, Marin Verrengia, Fabio Miraldi, Gianfranco Butera, Roberta Iacobelli, Benedetta Leonardi, Claudia Montanaro, Aurelio Secinaro, Lorenzo Galletti

“…Background: The emerging role of tricuspid regurgitation in the long-term outcome of the general population, poses the need for a review of its impact on patients with TOF and the timing for surgical PVR. …”
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Physical activity in kidney transplant recipients: benefits, barriers, interventions by Martyna Skweres, Mateusz Nieczyporuk, Szymon Pucyło, Gabriela Piotrowska, Katarzyna Ceglarz, Jan Pielaciński, Aleksander Rudnik, Kinga Sikora, Aleksandra Sikora

“…Exercise interventions, leading to improved physical functioning both pre- and post-transplant, have been demonstrated to lead to improved muscle strength, overall physical functioning, as well as cardiorespiratory performance. …”
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Non-parathyroid hypercalcemia in a patient with new-onset hyperthyroidism and silicone-induced granulomas: case report by Laura Montefusco, Giada Rossi, Iulia Petria, Ida Pastore, Ida Pastore, Paolo Fiorina, Paolo Fiorina, Paolo Fiorina, Paolo Fiorina

“…Rarer causes of hypercalcemia, such as hyperthyroidism and granulomatous diseases, need to be addressed after excluding the more prevalent etiologies, namely primary hyperparathyroidism and malignancies. …”
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Advances in Natural-Product-Based Fluorescent Agents and Synthetic Analogues for Analytical and Biomedical Applications by Soniya Joshi, Alexis Moody, Padamlal Budthapa, Anita Gurung, Rachana Gautam, Prabha Sanjel, Aakash Gupta, Surya P. Aryal, Niranjan Parajuli, Narayan Bhattarai

“…Naturally derived fluorescent compounds are generally more biocompatible and environmentally friendly. …”
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AITP-YOLO: improved tomato ripeness detection model based on multiple strategies by Wenyuan Huang, Wenyuan Huang, Yiran Liao, Peiling Wang, Ziao Chen, Ziao Chen, Ziqi Yang, Ziqi Yang, Lijia Xu, Jiong Mu, Jiong Mu

“…Secondly, a multi-scale feature fusion technique employing cross-level features is implemented in the feature fusion layer to amalgamate convolutions of varying sizes, enhancing the model's fusion capacity and generalization proficiency for features of diverse scales. …”
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Valorization of Andean Native Potatoes Through Chuño Processing: Effects of Potato Variety and Freezing Temperature on Physicochemical, Bioactive, Nutritional, and Technological Pr... by Elmer Robert Torres-Gutiérrez, Grimaldo Wilfredo Quispe-Santivañez, Jimmy Pablo Echevarría-Victorio, David Elí Salazar-Espinoza, Joselin Paucarchuco-Soto, Henry Juan Javier-Ninahuaman, Williams Esteward Castillo-Martinez, Rebeca Salvador-Reyes

“…Color differences were also noted, with P presenting reddish tones and a higher luminosity, whereas C had a more intense yellow hue linked to carotenoids. In general, −10 °C and −20 °C better preserved antioxidant compounds than −30 °C. …”
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A Normative Model Representing Autistic Individuals Amidst Autism Spectrum Phenotypic Heterogeneity by Joana Portolese, Catarina Santos Gomes, Vinicius Daguano Gastaldi, Cristiane Silvestre Paula, Sheila C. Caetano, Daniela Bordini, Décio Brunoni, Jair de Jesus Mari, Ricardo Z. N. Vêncio, Helena Brentani

“…PCA-projected dimensions supported normative modeling where a multivariate normal distribution was used to calculate percentiles. A Multidimensional General Functionality Score (MGFS) to evaluate new prospective single subjects was developed based on percentiles. …”
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The Ukrainian Pryazovye: composition, uniqueness, variability of the recreational development by Олександр Бейдик, Олександр Комлєв, Лариса Донченко, Ірина Арсененко, Олеся Топалова, Ірина Донець

“…So, the reassessment of the eco-health-improvement and tourist meaning of the Ukrainian Pryazovye, the "reflashing" of the strategy of its further development against this background becomes more than obvious. This topicality is reinforced with the analysis of the significant array of the publications from the subject-object essence of the research, which expands and deepens the theory of resource-recreational scientific and practical direction (the number of the new concepts has been introduced), emphasizes the anthropocentric character of recreational geography, gives 5 hypothetical scenarios of the development of recreational and tourist branch in the regional and the national format on the operational perspective and contains generalizing cartographic models of the development of the regional environmental and recreational and tourist function. …”
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Therapeutic effect of cardiac rehabilitation on patients with long COVID combined with coronary heart disease: a retrospective study by Hui Du, Xia Du, Xinyu Lei, Gang Wang, Zhengtao Wang, Yiting Du, Fangfang Bai, Dajiang Yuan

“…Comparison of differences between the two groups before and after treatment revealed that the CHD group had significantly worse cardiovascular measurements after SARS-CoV-2 infection than the non-CHD group.ConclusionPatients with long COVID combined with CHD have more severe symptoms, especially for their cardiac function. …”
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