Risk of adverse outcomes following urinary tract infection in older people with renal impairment: Retrospective cohort study using linked health record data. by Haroon Ahmed, Daniel Farewell, Nick A Francis, Shantini Paranjothy, Christopher C Butler

“…<h4>Methods and findings</h4>This was a retrospective cohort study using linked health record data from 795,484 patients from 393 general practices in England, who were aged ≥65 years between 2010 and 2016. …”
Get full text

Effects of the efficacy of the Yi Shen Tiao Gan formula on aromatase inhibitor associated musculoskeletal syndrome: a randomized controlled trial by Yan Zhang, Meiling Chu, Meina Ye, Yiqin Cheng, Hui Cong, Yulian Yin, Hongfeng Chen

Get full text

Atypical enteropathogenic E. coli are associated with disease activity in ulcerative colitis by Maximilian Baumgartner, Rebecca Zirnbauer, Sabine Schlager, Daniel Mertens, Nikolaus Gasche, Barbara Sladek, Craig Herbold, Olga Bochkareva, Vera Emelianenko, Harald Vogelsang, Michaela Lang, Anton Klotz, Birgit Moik, Athanasios Makristathis, David Berry, Stefanie Dabsch, Vineeta Khare, Christoph Gasche

Get full text

Developing a molecular diagnostic model for heatstroke-induced coagulopathy: a proteomics and metabolomics approach by Qingbo Zeng, Qingwei Lin, Longping He, Lincui Zhong, Ye Zhou, Xingping Deng, Nianqing Zhang, Qing Song, Qing Song, Jingchun Song, Jingchun Song

Get full text

Comparative efficacy of leukotriene modifier and inhaled corticosteroids in the complex treatment of steroid-naive patients with bronchial asthma combined with chronic obstructive... by Yu. I. Feshchenko, L. O. Yashyna, V. I. Ihnatieva, M. O. Polianska, S. H. Opimakh, I. V. Zvol, S. M. Moskalenko, H. L. Humeniuk, N. A. Vlasova, L. A. Halai

“…The duration of therapy was 12 weeks. General clinical methods, asthma control questionnaires, COPD questionnaire, physical tolerance evaluation (6-minute walk test), pulmonary function tests, quality of life assessment were performed to all the patients before and after the treatment course studied. …”
Get full text

Associations between brominated flame retardants exposure and non-alcoholic fatty liver disease: Mediation analysis in the NHANES by Yulan Cheng, Jingyi Su, Xiangdong Wang, Ruiyao Huang, Zixuan Zhao, Kai Tian, Tianxiang Gu, Xiaoke Wang, Lin Chen, Xinyuan Zhao

“…The association of BFRs with nonalcoholic fatty liver disease (NAFLD) in the general population is unclear. Meanwhile, limited studies have investigated the potential role of oxidative stress and inflammation in this link. …”
Get full text

Preliminary evaluation of a mindfulness intervention program in women with long COVID dysautonomia symptoms by Elizabeth Vandenbogaart, Matthew Figueroa, Diana Winston, Steve Cole, Julienne Bower, Jeffrey J. Hsu

“…Declines in CTRA gene expression did not vary significantly as a function of recent illness, COVID-19 hospitalization, demographic characteristics, or general medical history. …”
Get full text

Trypanosoma cruzi Mexican Strains Differentially Modulate Surface Markers and Cytokine Production in Bone Marrow-Derived Dendritic Cells from C57BL/6 and BALB/c Mice by Cecilia Gomes Barbosa, Tamires Marielem Carvalho Costa, Chamberttan Souza Desidério, Paula Tatiana Mutão Ferreira, Mariana de Oliveira Silva, César Gómez Hernández, Malú Mateus Santos, Rafael Obata Trevisan, Weslley Guimarães Bovi, Virmondes Rodrigues, Juliana Reis Machado, Luiz Eduardo Ramirez, Carlo José Freire de Oliveira, Marcos Vinícius da Silva

Get full text

Ultrasound-Mediated Non-Specific Splenic Immunopotentiation to Elicit Broad-Spectrum Anti-Neoplastic Effects by Dong W, Wang G, Li S, Wang Q, Li W, Liu H, Liang Y, Zhou Z, He X, Guo W, Yuan J, Chai Y, Geng J, Li Z

“…It fully demonstrated that FUS directly stimulated splenic immune cell proliferation and activation (especially NK and CD8 T cells) rather than CAP excitation to modulate splenic immune function. Particularly, NK cells are much more indispensable and important in responding to FUS stimulation for cancer suppression than CD8 T cells. …”
Get full text

AN ANTIHERO IN THE SPACE OF A SOUTH KOREAN DRAMA: IS IT OKAY TO NOT BE OKAY? / АНТИГЕРОЙ В ПРОСТРАНСТВЕ ЮЖНОКОРЕЙСКОГО СЕРИАЛА: НОРМАЛЬНО ЛИ БЫТЬ НЕНОРМАЛЬНЫМ?... by Tarasova Aleksandra V. / Тарасова А.В.

“…The article focuses on the image of an antihero in South Korean television series: its typical features, its functions, and interaction with the audience. The article opens with a brief outline of the antihero version that has been sought after by the global audience since the 2000s—a gifted sociopath, unable and unwilling to maintain the generally accepted format of interaction with other people. …”
Get full text

The Gluten-free diet and oncological prevention – the importance of a conscious lifestyle for physically active people – A Literature Review by Julia Wątor, Alicja Podolska, Patrycja Kolano, Jerzy Krzeszowiak, Barbara Chojnacka, Tomasz Pulanecki, Barbara Boba, Sylwia Bryksy, Aleksandra Ożga, Agnieszka Woźniacka

“…Aim of the Study: This review examines whether celiac patients are more prone to cancer and how a gluten-free diet modifies this risk. …”
Get full text

A Proposed Diagnostic and Treatment Algorithm for the Management of Lumbar Discogenic Pain by Lorio MP, Beall DP, Myers TJ, Naidu RK, McRoberts WP, Davis TT, Gage EG, Calodney AK, Verrills P, De Palma MJ, Amirdelfan K, Block JE

“…Treatment options are stratified by DDD severity to include conservative management (grades 1 and 2), minimally-invasive intradiscal therapies (grades 3 to 7), and more invasive surgical procedures (grade 8). Recognizing that the management program for patients with lumbar discogenic pain can be highly personalized, the treatment options recommended by this algorithm should be considered general guidance.Conclusion: The proposed algorithm offers an easy-to-use clinical tool for identifying, evaluating and treating patients with lumbar discogenic pain. …”
Get full text

Sensitivity Study of Multiconstellation GNSS-R to Soil Moisture and Surface Roughness Using FY-3E GNOS-II Data by Zhongmin Ma, Adriano Camps, Hyuk Park, Shuangcheng Zhang, Xiaojun Li, Jean-Pierre Wigneron

“…As compared with higher SM, SR is more sensitive at lower SM. This highlights the shortcomings of using linear models to retrieve SM. …”
Get full text

Exploring the thermodynamic description of a simulation of flocking birds by Alexander V. Mantzaris, George-Rafael Domenikos

“…The energy of the birds is defined, and from the distribution function, the entropy, internal energy, temperature, heat flux, and pressure are defined. …”
Get full text

Exponentiated Inverse Rayleigh Distribution and an Application to Coating Weights of Iron Sheets Data by Gadde Srinivasa Rao, Sauda Mbwambo

“…This article aims to introduce a generalization of the inverse Rayleigh distribution known as exponentiated inverse Rayleigh distribution (EIRD) which extends a more flexible distribution for modeling life data. …”
Get full text

Network security traffic detection and legal supervision based on adaptive metric learning algorithm by Liu Zhen

“…Using the vertex weighted function algorithm, we can analyze the Time complexity of the original algorithm and calculate more accurate time values. …”
Get full text

Neuroimmune Pain and Its Manipulation by Pathogens by Kevin W. Lozo, Athena Aktipis, Joe Alcock

“…These complementary systems generally protect hosts from infections. At the same time, neuroimmune pain is vulnerable to manipulation. …”
Get full text

An automatic adaptive method to combine summary statistics in approximate Bayesian computation. by Jonathan U Harrison, Ruth E Baker

“…However, some summary statistics contain more information about parameters of interest than others, and it is not always clear how to weight their contributions within the ABC framework. …”
Get full text

Small fiber pathology in fibromyalgia syndrome by Claudia Sommer, Nurcan Üçeyler

“…Microneurography in particular has shown increased spontaneous activity, mechanosensitivity, and enhanced activity-induced slowing in C fibers of patients with fibromyalgia. Generalized reduction of skin innervation, ie, proximally and distally, was associated with higher symptom severity and more pronounced central nervous system changes as seen in magnetic resonance tomography. …”
Get full text

Asymmetric excitatory synaptic dynamics underlie interaural time difference processing in the auditory system. by Pablo E Jercog, Gytis Svirskis, Vibhakar C Kotak, Dan H Sanes, John Rinzel

“…We demonstrate, and support using a biophysically based computational model, that a bilateral asymmetry in excitatory post-synaptic potential (EPSP) slopes provides a robust compensatory delay mechanism due to differential activation of low threshold potassium conductance on these inputs and permits MSO neurons to encode physiological ITDs. We suggest, more generally, that the dependence of spike probability on rate of depolarization, as in these auditory neurons, provides a mechanism for temporal order discrimination between EPSPs.…”
Get full text