rcprd: An R package to simplify the extraction and processing of Clinical Practice Research Datalink (CPRD) data, and create analysis-ready datasets. by Alexander Pate, Rosa Parisi, Evangelos Kontopantelis, Matthew Sperrin

“…Raw CPRD data is provided in thousands of.txt files, making querying this data cumbersome and inefficient. rcprd saves the relevant information into an SQLite database stored on the hard drive which can then be queried efficiently to extract required information about individuals. rcprd follows a four-stage process: 1) Definition of a cohort, 2) Read in medical/prescription data and save into an SQLite database, 3) Query this SQLite database for specific codes and tests to create variables for each individual in the cohort, 4) Combine extracted variables into a dataset ready for statistical analysis. Functions are available to extract common variable types (e.g., history of a condition, or time until an event occurs, relative to an index date), and more general functions for database queries, allowing users to define their own variables for extraction. …”
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Occurrence and potential mechanism of holin-mediated non-lytic protein translocation in bacteria by Thomas Brüser, Denise Mehner-Breitfeld

“…However, there are more and more examples known for non-lytic holin-dependent secretion of proteins by bacteria, indicating that holins somehow can transport proteins without causing large membrane lesions. …”
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Biological age and aging rate of patients with vibration disease caused by the actions of the whole-body vibration in the post-exposure period. by S. Hryniuk

“…The study of vibration disease in the post-exposure period was done rare. In modern medicine, more attention is paid to assessing the functional state of the human body in general and specifically its "vitality". …”
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USING OF MSC WITH DIFFERENT ONTOGENETIC MATURITY FOR CORRECTION OF CHRONIC FIBROSING LIVER DAMAGE by M. Y. Shagidulin, A. A. Gorkun, N. A. Onishchenko, M. E. Krasheninnikov, I. M. Iljinsky, N. P. Mogeiko, L. V. Bashkina, I. N. Saburina, V. I. Sevastjanov, S. V. Gautier

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Use of rituximab in connective tissue disease-associated interstitial lung disease: a narrative review by Chenhao Xu, Zewei Xu, Jin Ren

“…The article synthesizes findings from studies assessing rituximab’s effects on lung function, clinical outcomes, and safety across distinct subtypes of connective tissue disease. …”
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Decoding public sentiment topics in google map reviews on urban infrastructure development of belt and road initiative by Yue Xiong, Jiayong Liang, Chenghe Guan

“…However, high investment areas experience more polarized reviews, indicating unmet expectations. …”
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The Sensitivity Analysis of Whitecapping Dissipation Term for Calibration of SWAN Model Forced with ERA5 Winds in the Gulf of Oman by Amir Siahsarani, Majid Azadi, Behzad Layeghi, Davoud Babazadeh

“…A more common method is to calibrate the wave model, which is generally implemented by setting certain coefficients in these models. …”
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Modal Analysis of QP and LP Solution in Steady-state Optimization Layer of Two-layer Structure MPC by WANG Hongrui, ZHANG Xin, LIU Bowen, LIN Na, ZOU Tao

“…In order to solve the problems of generalized demand and parameter configuration in the engineering application of two-layer predictive control, a series of linear programming (LP) or quadratic programming (QP) problems are formed by studying the standardization process of the two-stage solution strategy in the steady-state optimization layer. …”
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Metabolic Risk Factors and Their Impact on Quality of Life in Patients with Pancreatic Cancer, Acute or Exacerbated Chronic Pancreatitis by I. N. Grigor’eva, O. V. Efimova, N. L. Tov, T. S. Suvorova, D. L. Nepomnyashchikh

“…Quality of life indicators were higher in group 1 than in group 2 on four SF-36 scales: bodily pain (68.1 ± 5.1 and 36.8 ± 2.0; p < 0.001), general health (51.1 ± 2.5 and 38.0 ± 1.7 points; p < 0.001), social functioning (74.7 ± 3.0 and 64.5 ± 2.2 points; p = 0.007), role emotional functioning (28.2 ± 5.2 and 12.5 ± 3.1 points; p = 0.007) and in the general domain “physical component of health” (40.2 ± 1.0 and 33.6 ± 0.8 points; p < 0.001). …”
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Mechanical Solving a Few Fractional Partial Differential Equations and Discussing the Effects of the Fractional Order by Kai Fan, Cunlong Zhou

“…In the “The Explanation and Discussion” section, a more generalized auxiliary equation is used to further emphasize the rules, which has certain reference value for the construction of the new auxiliary equations. …”
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Les groupes binominaux de type N2’s N1, N1 of N2 et N2N1 by Evelyne Chabert

“…It seeks to evaluate the validity of Adamczewski’s model, which proposes that the difference lies in the degree of ‘fusion’ between the referents of N1 and N2.An analysis of occurrences taken from the TLD corpus shows that Adamczewsi’s theory fails to account for the alternation and that, more generally, it exhibits the main invalidating features of a dysfunctional model: lack of universality, epistemic circularity, irrefutability and lack of predictive power. …”
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Applying conditional optimization to determine the allowable loads on flexurally rigid threads by D. A. Tarasov

“…At the same time, to achieve this goal, the provisions of the strength of materials, as well as the apparatus of integral and differential calculation of functions of one or more variables, were used.Result. …”
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The impact of BST1 rs4698412 variant on Parkinson’s disease progression in a longitudinal study by Hao-Ling Xu, Hao-Ling Xu, Yu Yang, Yu Yang, Yu Yang, Li-Na Chen, Li-Na Chen, Yun-Jing Li, Yun-Jing Li, Guo-En Cai, Guo-En Cai, Ying-Qing Wang, Ying-Qing Wang, Yan-Hong Weng, Yan-Hong Weng, Xiao-Ling Lin, Xiao-Ling Lin, Jing Jian, Jing Jian, Xiao-Chun Chen, Xiao-Chun Chen, Qin-Yong Ye, Qin-Yong Ye

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Determining the Bioavailability Percentage of Bone Ash Phosphorus Compared to Monocalcium Phosphate and Its Effect on Performance, Bone Quality and Phosphorus Digestibility in Broi... by Mohammad Sedghi, Zahra Sarrami, Raziye Ghasemi, Mahdi Zanghae

“…Phosphorus plays a vital role in muscle function, enzyme activity, lipid metabolism, bone mineralization, maintaining osmotic and acid-base balance, energy metabolism, amino acid metabolism, and protein synthesis. …”
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Investigating Women's Preferences in the Public Spaces of Gated Communities - A Case Study of Atisaz Residential Complex by Sara Anbari, Seyed Abbas Yazdanfar, Seyed Hadi Ghoddusi Far, Azadeh Shahcheraghi

“…These themes describe the requirements and preferences based on lifestyle and indicate that some requirements are more general, while others include unique women's needs that must be considered in the design and implementation of future residential environments.…”
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Les enjeux du vernaculaire noir-américain dans la traduction baudelairienne du « Scarabée d’or » : lorsque le dialecte porte l’empreinte du sens by Romain Rivaux

“…Such an examination requires the meticulous study of the decisions made by Charles Baudelaire to represent African-American language and mindset, Edgard Allan Poe’s literary devices and subversive language, and more generally the real issue of this well-known short story, i.e., representing slavery in pre-Civil War South Carolina. …”
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Media Matters: How Information Release Shapes Monkeypox Vaccination Willingness by Huan Wang, Nan Wu

“…Compared to thematic framing, episodic framing generally enhances respondents’ willingness to vaccinate. …”
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It’s long-term, well it’s for life basically: Understanding and exploring the burden of immunoglobulin treatment in patients with primary immunodeficiency disorders by Georgina Jones, Eva Brown Hajdukova, Esmee Hanna, Rosie Duncan, Brendan Gough, Jane Hughes, Debbie Hughes, Fran Ashworth, Johan Prevot, Jose Drabwell, Leire Solis, Nizar Mahlaoui, Anna Shrimpton

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L’habitat de la Sente à Grentheville (Calvados), vie-xe siècle, dans le contexte du terroir de Mondeville Saint-Martin by Claire Hanusse

“…Examination of associated finds raises questions concerning the settlement’s function, its position in the hierarchy of early medieval habitat sites and more generally its place in a landscape densely occupied from prehistory until the end of the Middle Ages, as demonstrated by archaeology over the last forty years.…”
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Underwater Sound Speed Profile Inversion Based on Res-SACNN from Different Spatiotemporal Dimensions by Jiru Wang, Fangze Xu, Yuyao Liu, Yu Chen, Shu Liu

“…The Res-SACNN model not only shows more superior inversion ability in the comparison with other deep-learning models, but also achieves strong generalization and real-time performance while maintaining low complexity, providing an improved technical tool for SSP estimation and sound field perception.…”
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