Suggested Topics within your search.
Suggested Topics within your search.
-
11581
Hyodeoxycholic Acid Ameliorates Metabolic Syndrome Through Pathways of Primary Bile Acid Synthesis and Fatty Acid Degradation: Insights From a Rat Model
Published 2025-05-01“…Wes assays validated that FXR, CYP7A1, CYP7B1, PPARα, CPT1, CPT2, FABP1, HMGCS1 and HMGCS2 proteins in MS rats exhibited significant changes after HDCA treatment (p< 0.05), and this was more effective than metformin treatment.Conclusion: These study is the first to highlight HDCA as a therapeutic candidate for MS and provides new insights into the BA-MS axis, though further validation is needed. …”
Get full text
Article -
11582
Assessing Maritime Search and Rescue Accessibility from South China Sea Islands and Reefs to Shipping Routes
Published 2025-07-01“…In this study, a Voronoi diagram was used to spatially configure the South China Sea islands and reefs and indicate their functional areas. Subsequently, multilevel buffer zones were utilized to grade their SAR ranges. …”
Get full text
Article -
11583
Alkaline-Potassium Ferrate Pretreatment Promoting Acid Production Through Co-Fermentation of Waste Activated Sludge and Corn Straw
Published 2025-04-01“…Microbial community analysis revealed a reduction in the Shannon index, with a notable enrichment of fermentation-related functional bacteria, including Firmicutes and Bacteroidota. …”
Get full text
Article -
11584
Navigating HOPE (Hypermobile Online Pain managemEnt): Perspectives and Experiences From People With Hypermobile Ehlers–Danlos Syndrome or Hypermobility Spectrum Disorder on a Condi...
Published 2025-02-01“…Four themes emerged: (1) The biopsychosocial approach to understanding pain used in the HOPE programme was acceptable and appropriate, (2) benefits of the programme were stronger for those who were newer on their hEDS/HSD journey, (3) self‐guided reflections included in the programme required headspace and personal meaning and (4) participants desired more adaptable content and programme functionality. …”
Get full text
Article -
11585
How does soil carbon sequestration affect greenhouse gas emissions from a sheep farming system? Results of an life cycle assessment case study
Published 2021-05-01“…In order to provide a more comprehensive analysis, we used the following FUs: 1 kg of fat and protein corrected milk (FPCM) and 1 ha of utilised agricultural area (UAA). …”
Get full text
Article -
11586
WORK EXPERIENCE INTERNSHIP THROUGH THE EYES OF TECHNICAL UNIVERSITY STUDENTS (ON THE MATERIALS OF SOCIOLOGICAL RESEARCH)
Published 2015-05-01“…The results show that a third of fifth-year students are not satisfied with the work experience internship organization by the university and host company actions, more than a quarter of students are not ready to practical work, 40% feel the clear lack of practical skills in their future profession. …”
Get full text
Article -
11587
Effect of early neuroendovascular team involvement in acute stroke protocol: a retrospective study
Published 2025-06-01“…Favorable neurological outcomes at discharge (mRS 0–2) were more frequent in the protocol group (44.4% vs. 31.9%; adjusted odds ratio: 2.92, 95% confidence interval [CI]: 1.83–4.66). …”
Get full text
Article -
11588
Explainable multi-modal radiomics for early prediction of liver metastasis in rectal cancer: a multicentric study
Published 2025-06-01“…The SHAP method elucidated the model’s functionality by highlighting key feature contributions. …”
Get full text
Article -
11589
Factors Associated With the 30-day Readmission Rate in Patients With Heart Failure
Published 2025-03-01“…The data were analyzed using inferential statistics, including t-test, chi-square test/Fisher’s exact test and multiple logistic regression analysis. Results: Among patients, 181(58%) were over 65 years of age, 65.7% were male and more than 88% were married. …”
Get full text
Article -
11590
Choosing the Best Digital Health Literacy Measure for Research: Mixed Methods Study
Published 2025-04-01“…They should identify beneficiaries of digital health services, measure the impact of dHL interventions, and objectively evaluate functional skills. These tools should be evidence-based, validate instruments, interpret dHL results, and capture diverse experiences to reveal health behaviour changes. …”
Get full text
Article -
11591
Identifying Current Practices and Areas for Improvement in Medication Management During Care Transition Through an Interprofessional Collaboration Framework
Published 2025-07-01“…Team functioning: common in hospital settings, but inconsistent during transition; 5. …”
Get full text
Article -
11592
CLOUD COMPUTING AND BIG DATA AS CONVERGENT TECHNOLOGIES FOR RETAIL PRICING STRATEGIES OF SMEs
Published 2014-05-01“…Furthermore, we present how we use Exalead CloudView platform to search for weak signals in big data by analyzing multimedia data (text, voice, picture, video) and mining online social networks. The analysis makes not only customer profiling possible, but also brand promotion in the form of coupons, discounts or upselling to generate more sales, thus providing the opportunity for retailer SMEs to connect directly to its customers in real time. …”
Get full text
Article -
11593
Predicting the Likelihood of Operational Risk Occurrence in the Banking Industry Using Machine Learning Algorithms
Published 2025-12-01“…Four key databases are required: internal loss event data, external loss event data, scenario-based analysis data, and a database of business environment and internal control factors.Compared to other banking risks, such as credit and market risks, measuring, monitoring, and managing operational risk is considerably more complex. …”
Get full text
Article -
11594
Effects of Mg-Palygorskite Modified Biochar on the Growth of <i>Sedum alfredii</i> Hance in Heavy Metal Contaminated Soil
Published 2025-03-01“…This study provides data support for the development of functionalized biochar for the remediation of heavy metal pollution in soil.…”
Get full text
Article -
11595
Long non-coding RNA MIR22HG impedes the progression of anaplastic thyroid carcinoma via targeting miR-141-3p/PTEN/AKT axis
Published 2025-08-01“…Functional analysis showed that overexpression of MIR22HG attenuated the proliferation and metastasis of ATC both in vitro and in vivo. …”
Get full text
Article -
11596
Screening and mechanistic study of natural compounds that enhance T cell anti-tumor effects post-heat treatment
Published 2025-03-01“…By triggering the generation of heat shock proteins and facilitating mitochondrial energy supply, the 39°C treatment amplified the anti-tumor functions of T cells. By analyzing the data, we identified 3 injectable solutions and more than 20 effective monomers capable of further enhancing the tumor-killing ability of T cells. …”
Get full text
Article -
11597
RehabHand—A New Physical Rehabilitation Training Dataset: Construction and Benchmark Performances of the Relevant Hand Tasks
Published 2025-01-01“…We report a thorough performance analysis of the neuronal network models for the constructed dataset. …”
Get full text
Article -
11598
The Capabilities of Optical and C-Band Radar Satellite Data to Detect and Understand Faba Bean Phenology over a 6-Year Period
Published 2025-06-01“…These double logistic functions are capable of reproducing the differences in phenological development observed between fields and years, providing a reference set of functions that can be used to monitor the phenological development of faba beans in real time. …”
Get full text
Article -
11599
Non-Diffractive Wavefront-Shaping Intraocular Lens with Extended Depth of Focus: First Implantation Experience
Published 2023-01-01“…Purpose. Analysis of short-term clinical and functional results of implantation of a new non-diffractive IOL with expanded depth of focus.Patients and methods. …”
Get full text
Article -
11600
SOC: clay ratio: A mechanistically-sound, universal soil health indicator across ecological zones and land use categories?
Published 2024-12-01“…Moreover, we could not confirm a meaningful functional relation between the SOC: clay ratio and the quality of soil structure derived from visual assessment. …”
Get full text
Article