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11501
Deciphering the Transcriptional Metabolic Profile of Adipose-Derived Stem Cells During Osteogenic Differentiation and Epigenetic Drug Treatment
Published 2025-01-01“…Furthermore, this study underscores the potential of epigenetic drugs like RG108 to enhance ASC properties, paving the way for more effective and personalized cell-based therapies for bone regeneration.…”
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11502
Transgenic Maize of <i>ZmMYB3R</i> Shapes Microbiome on Adaxial and Abaxial Surface of Leaves to Promote Disease Resistance
Published 2025-02-01“…In OE plants, more beneficial microbes accumulated on the phyllosphere, while pathogenic ones diminished, especially on the abaxial surface of <i>ZmMYB3R</i> leaves. …”
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11503
Patellar motion and dysfunction of its stabilizers in a biomechanical model of the knee joint
Published 2024-04-01“…The presented biomechanical model provides a detailed analysis of the normal dynamics of the patella and the role of different anatomical structures in its functioning and can be used for further experiments investigating of the patellar movement. …”
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11504
Annual cycle variations in the gut microbiota of migratory black-necked cranes
Published 2025-02-01“…And the summer samples exhibited higher alpha (Simpson and Shannon), beta diversity (Bray-Curtis and UniFrac) and more diverse functions in gut microbiota compared to other seasons. …”
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11505
The Moroccan <i>Meska Horra</i>: A Natural Candidate for Food and Therapeutic Applications
Published 2025-03-01“…Molecular docking indicated that caryophyllene and its oxide are key bioactive compounds, although their effectiveness may be enhanced by synergistic interactions. Comparative analysis of extraction methods showed that headspace (HS) extraction captured highly volatile monoterpenes, while solid-phase microextraction (SPME) and ultrasound-assisted SPME (US-SPME) were more effective at extracting compounds such as <i>cis</i>-ocimene and limonene. …”
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11506
A simple scalable extracellular vesicle isolation method using polyethylenimine polymers for use in cellular delivery
Published 2024-06-01“…Furthermore, once eluted from the polymers, the isolated EVs were able to deliver functional protein cargo to recipient cells. Overall, our data support PEI-based isolation of EVs as a simple, rapid method for the recovery of functional EVs.…”
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11507
Modulating physical properties of ASnF3 (A = K, Rb) perovskites under pressure: Insights for enhanced optoelectronic performance via first-principles
Published 2025-09-01“…The mechanical properties of the compounds directly reflect their ductile and anisotropic characteristics, both of which are significantly influenced by external pressure. Analysis of the elastic functions indicates that these compounds become even more versatile for various potential applications when subjected to hydrostatic pressure. …”
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11508
Eliciting an immune-mediated antitumor response through oncolytic herpes simplex virus-based shared antigen expression in tumors resistant to viroimmunotherapy
Published 2021-10-01“…We verified the virus genotypically and phenotypically and then tested it in an oHSV-resistant orthotopic model (including immunophenotypic analysis), in flank and in T cell-deficient mouse models. …”
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11509
Myths and misconceptions of intimate partner violence among sexual and gender minorities: a qualitative exploration
Published 2024-12-01“…BackgroundIntimate partner violence (IPV), referring to different forms of violence or abuse between two or more intimate partners, negatively impacts physical and mental health, performance in various settings, and familial functioning, leading to long-term adverse outcomes. …”
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11510
Screening for endocrine-disrupting chemicals in the serum and cerebrospinal fluid of patients with autoimmune encephalitis
Published 2025-07-01“…Our findings support an evidence base for the effects of specific chemicals may impair neural functions.…”
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11511
The application of One Health concept in China and its practice and innovation in cross-sector cooperation
Published 2025-06-01“…However, to fully realize this concept, more efforts are still needed in the areas of cooperation mechanisms, professional talent training, information exchange and social awareness. …”
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11512
Allelic Variation of Hd17 for Rice Heading Date is Caused by Natural Selection
Published 2025-03-01“…Selection for natural variated alleles for heading date genes is an important manifestation of rice domestication that allows rice to spread to more broad geographic areas. In this study, three alleles of the Hd17 gene for heading date were identified by sequence analysis of 14 single-segment substitution lines, 6 wild rice species, and 2524 accessions of O. sativa. …”
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11513
GWAS and RNA-seq reveal novel loci and genes of low-nitrogen tolerance in cucumber (Cucumis sativus L.)
Published 2025-06-01“…Furthermore, functional validation of the candidate gene CsaV3_7G035390 (encoding a GATA9 transcription factor) was performed using virus-induced gene silencing (VIGS), which demonstrated that silencingn this gene significantly enhanced soil plant analysis development (SPAD) and leaf of nitrogen accumulation in cucumber, indicating its negative regulatory role in low-nitrogen tolerance. …”
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11514
Trait-mediated responses and co-occurrence patterns of breeding steppe birds under human footprint in Inner Mongolia
Published 2025-09-01“…We conducted standardized point-count surveys across a gradient from intact grasslands to urbanized areas, integrating species occurrence data, functional traits and the Human Footprint Index (HFI). …”
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11515
Unlocking the Potential of Remanufacturing Through Machine Learning and Data-Driven Models—A Survey
Published 2024-12-01“…As a key strategy for achieving a circular economy, remanufacturing involves bringing end-of-use (EoU) products or cores back to a ‘like new’ condition, providing more affordable and sustainable alternatives to new products. …”
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11516
A Sociological Study of Monetary Attitudes among Citizens of Tehran
Published 2025-06-01“…Currently, the cultural and social functions of money—understood as a "fait social total"—are undergoing significant changes. …”
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11517
The Immunohistochemical Prognostic Value of Nuclear and Cytoplasmic Silent Information Regulator 1 Protein Expression in Saudi Patients with Breast Cancer
Published 2025-01-01“…Results: All BC subtypes expressed more nuclear SIRT1 proteins than their cytoplasm counterparts. …”
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11518
A Quantitative Risk Assessment Model for <i>Listeria monocytogenes</i> in Non-Ready-to-Eat Frozen Vegetables
Published 2024-11-01“…In a reference scenario, the model estimated that 9.4% of 500 g packages of frozen vegetables would be contaminated, although at mean levels lower than 10 CFU/g, and assuming that 20% of the portions of frozen vegetables would be left to thaw at room temperature for 2 h, the lot-level mean risk of listeriosis in the susceptible population would be 2.935 × 10<sup>−14</sup> (median 5.446 × 10<sup>−15</sup>) for uncooked 50 g servings and 2.765 × 10<sup>−17</sup> (median 5.184 × 10<sup>−18</sup>) for cooked 50 g servings. Analysis of selected scenarios suggested that not cooking the non-RTE product contributes to the risk to a greater extent than the level of contamination in the incoming raw vegetables, the latter in turn being more influential than the level of contamination in the processing environment. …”
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11519
Micro-electrical discharge coating of AlCoCrFeNi high entropy alloy on MgAz31B to enhance the corrosion and wear resistance
Published 2025-05-01“…The hydrophobic nature of coating can be advantageous for various biological functions, particularly in protein interactions. Thus, employing high entropy alloy coatings on magnesium alloys holds significant promise for optimizing their corrosion resistance properties, and make more suitable for implant applications.…”
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11520
Prevalence and clinical significance of loneliness in older patients admitted to acute hospital wards
Published 2025-10-01“…Conclusion: Loneliness was reported by more than half of older adults hospitalized in acute medical wards, and was associated with depressive symptoms and disability. …”
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