Fluorescence spectroscopic profiling of urine samples for predicting kidney transplant rejection by Zhe Yang, Minrui Zhang, Xianduo Li, Zhipeng Xu, Yi Chen, Xiaoyu Xu, Dongdong Chen, Lingquan Meng, Xiaoqing Si, Jianning Wang

“…In contrast, urine serves as a direct indicator of the graft's degenerative stage and provides a more accurate measure than peripheral blood analysis, given its non-invasive collection of kidney-specific metabolite. …”
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Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling by Asra Asgharzadeh, Mubarak Patel, Martin Connock, Sara Damery, Iman Ghosh, Mary Jordan, Karoline Freeman, Anna Brown, Rachel Court, Sharin Baldwin, Fatai Ogunlayi, Chris Stinton, Ewen Cummins, Lena Al-Khudairy

“…Treatment with insulin is aimed at replicating the function of the pancreas to manage hyperglycaemia and avoid hypoglycaemia. …”
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Adaptive changes in the intestinal microbiota of giant pandas following reintroduction by Rui Ma, Xiang Yu, Wenlei Bi, Jiabin Liu, Zusheng Li, Rong Hou, Wei Wu, Ping Li, Hui He, Mei Zhang, Xi Yang, Hong Yang, Xiaodong Gu, Haijun Gu, Qian Zhang, Dunwu Qi

“…Streptococcus was significantly enriched in the training period, but Clostridium became significantly enriched after being released. KEGG functional prediction analysis revealed that during the stable phase, carbohydrate and amino acids metabolism was significantly reduced, while pathways associated with cofactors and vitamins, other amino acids, lipids, nucleotide and energy metabolism were markedly enriched. …”
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From Code to Life: The AI‐Driven Revolution in Genome Editing by Zhidong Li, Wasi Ullah Khan, Genxiang Bai, Chao Dong, Jungang Wang, Youpeng Zhang, Chong Wang, Hongbin Zhang, Wenyi Wang, Ming Luo, Fei Chen

“…AI‐driven models, such as deep learning‐based predictors and protein language models, enable more accurate sgRNA design, novel Cas protein discovery, and enhanced gene regulatory network analysis. …”
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Exposure to ambient air pollution over developmental stages induced neurodevelopmental impairment in mice offspring via microbiome-gut-brain axis by Zijun Yang, Yi Zhang, Shanshan Ran, Jingyi Zhang, Yonggui Gao, Yali Zhang, Xinyue Li, Baozhuo Ai, Shengtao Wei, Fei Tian, Guang Jia, Hualiang Lin, Zhangjian Chen, Zilong Zhang

“…Alterations in the compositions and functions of gut microbiome were also revealed by fecal metagenomic sequencing. …”
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Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote. by Jonathan A Eisen, Robert S Coyne, Martin Wu, Dongying Wu, Mathangi Thiagarajan, Jennifer R Wortman, Jonathan H Badger, Qinghu Ren, Paolo Amedeo, Kristie M Jones, Luke J Tallon, Arthur L Delcher, Steven L Salzberg, Joana C Silva, Brian J Haas, William H Majoros, Maryam Farzad, Jane M Carlton, Roger K Smith, Jyoti Garg, Ronald E Pearlman, Kathleen M Karrer, Lei Sun, Gerard Manning, Nels C Elde, Aaron P Turkewitz, David J Asai, David E Wilkes, Yufeng Wang, Hong Cai, Kathleen Collins, B Andrew Stewart, Suzanne R Lee, Katarzyna Wilamowska, Zasha Weinberg, Walter L Ruzzo, Dorota Wloga, Jacek Gaertig, Joseph Frankel, Che-Chia Tsao, Martin A Gorovsky, Patrick J Keeling, Ross F Waller, Nicola J Patron, J Michael Cherry, Nicholas A Stover, Cynthia J Krieger, Christina del Toro, Hilary F Ryder, Sondra C Williamson, Rebecca A Barbeau, Eileen P Hamilton, Eduardo Orias

“…Like other ciliates, this species has separate germline and soma functions that are embodied by distinct nuclei within a single cell. …”
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Multiparametric MRI for the improved diagnostic accuracy of Alzheimer's disease and mild cognitive impairment: Research protocol of a case-control study design. by Albert Dayor Piersson, Buhari Ibrahim, Subapriya Suppiah, Mazlyfarina Mohamad, Hasyma Abu Hassan, Nur Farhayu Omar, Mohd Izuan Ibrahim, Ahmad Nazlim Yusoff, Normala Ibrahim, M Iqbal Saripan, Rizah Mazzuin Razali

“…The structural images will be analysed using Computational Anatomy Toolbox-12, functional images will be analysed using Statistical Parametric Mapping-12, DPABI (Data Processing & Analysis for Brain Imaging), and Conn software, while DTI and 1H-MRS will be analysed using the FSL (FMRIB's Software Library) and Tarquin respectively. …”
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Cognitive recovery of post critical care patients with and without COVID-19: differences and similarities, an observational study by Anna Gorsler, Christiana Franke, Anneke Quitschau, Nadine Külzow

“…Critically ill patients with or without SARS-CoV-2 infection (at least mechanically ventilated for one week) underwent repeated standardized assessments during their subsequent inpatient rehabilitation stay. Cognitive functions (information processing speed, learning, recognition, short-term and working-memory, word fluency, flexibility) assigned to different domains (attention, memory, executive functions) were assessed as primary outcome. …”
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Investigation of the genetic diversity of gut mycobiota of the wild and laboratory mice by Ji-Xin Zhao, Hany M. Elsheikha, Kai-Meng Shang, Jin-Wen Su, Yong-Jie Wei, Ya Qin, Zi-Yu Zhao, He Ma, Xiao-Xuan Zhang

“…We cultured 428 fungal strains from the cecal mycobiota, sequenced the whole genome of 48 selected strains, and identified 500,849 genes. Functional annotation analysis revealed multiple pathways related to energy metabolism, carbohydrate metabolism, fatty acid metabolism, and enzymes involved in the degradation of polysaccharides, lipids, and proteins, and secondary metabolite biosynthesis. …”
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Análisis de imágenes mediante el método de los momentos usando funciones de base continuas a intervalos (PCBF) by Sergio Domínguez

“…Analyzing such discontinuous objects by means of continuous functions can lead to undesired results, as the Gibbs phenomenon, that can be avoided by simply shifting to discontinuous basis for the analysis, getting better approximations to the described object. …”
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Natural Products from Herbal Medicine Self‐Assemble into Advanced Bioactive Materials by Xiaohang Guo, Weikang Luo, Lingyu Wu, Lianglin Zhang, Yuxuan Chen, Teng Li, Haigang Li, Wei Zhang, Yawei Liu, Jun Zheng, Yang Wang

“…Abstract Novel biomaterials are becoming more crucial in treating human diseases. However, many materials require complex artificial modifications and synthesis, leading to potential difficulties in preparation, side effects, and clinical translation. …”
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Assessment of CPME as Sustainable Low VOC Alternative to Hexane: Optimization of Extraction Efficiency and Bioactive Compound Yield from Fenugreek Seed Oil Using Computational and... by Ameni Ben Abdennebi, Emna Chaabani, Mariem Ben Jemaa, Majdi Hammami, Saber Khammassi, Salma Nait Mohamed, Wissem Aidi Wannes, Ibtissem Hamrouni Sellami, Anne-Sylvie Fabiano Tixier, Iness Bettaieb Rebey

“…Solubility computational predictions analysis revealed that CPME exhibits superior solvation power compared to hexane. …”
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Potential influence of geomagnetic activity on blood pressure statistical fluctuations at mid-magnetic latitudes by Pengzhi He, Chen Li, Minlan Xu, Ruilong Guo, Alexander William Degeling, Timo Pitkänen, Yude Bu, Xiangyun Zheng, Yue Zhang, Xianghong Jia, Anmin Tian, Chenyao Han, Shifeng Wang, Tianlu Chen, Jiangping Fang, Shaowei Sun, Wenlong Liu, Jinbin Cao, Kimmen Quan, Zhiyuan Cong, Dedong Ma, Qiugang Zong, Suiyan Fu, Shutao Yao, Huanhu Zhang, Quanqi Shi

“…Additionally, we conducted a comparative analysis of the influence of other environmental factors (air temperature and PM2.5) on BP. …”
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Isolation and Characterization of Lignin from Oil Palm Shells using a Precipitation Method with Sulfuric Acid and Polyaluminum Chloride as Coagulant by Eny Kusrini, Ria Yolanda Arundina, Anwar Usman, Resti Marlina, Bambang Subiyanto, Volkan Degirmenci, Nofrijon Sofyan, Yudan Whulanza

“…The isolated lignin was identified using Fourier Transform Infrared (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM). Based on the FTIR analysis, lignin was successfully separated from cellulose. …”
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Allying cobalt nanoclusters with carbon nanofibers for selectively electrocatalytic hydrogenation of unsaturated aldehyde with water as hydrogen source by Xinyu Yang, Sheng-Hua Zhou, Xiaofang Li, Xin-Tao Wu, Qi-Long Zhu

“…The further in-situ spectroscopy analysis and density functional theory calculations revealed the more preferred adsorption of CC bond and easier water dissociation to give the active H atoms over the Co nanoclusters, which shed light on the hydrogenation mechanism over this electrocatalyst. …”
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Long-term dental follow-up in hematological stem cells transplantation children by Luiz Alberto Valente Júnior, Paulo Sérgio da Silva Santos, Fabio Luiz Coracin, Alexandre Viana Frascino, Marcelo Fava, Vicente Odone Filho

“…Temporomandibular joint dysfunction was found to be more prevalent in the patients who was diagnosed with graft-versus-host disease. …”
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TP53 and KMT2D mutations associated with worse prognosis in peripheral T‐cell lymphomas by Lingling Wang, Lei Yang, Fangshu Guan, Jing Chen, Yuexin Cheng, Yuqing Miao, Jingsong He, Zhen Cai, He Huang, Yi Zhao

“…When mutant genes are classified by functional group, the most prevalent mutations are related to epigenetics and signal transduction. …”
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A mindfulness-based, cognitive, social, digital relapse-prevention intervention for youth with depression in Australia: study protocol for a randomised controlled trial of Rebound by Mario Alvarez-Jimenez, Sarah Bendall, Peter Koval, Simon Rice, Daniela Cagliarini, Lee Valentine, Penni Russon, Jess Phillips, Reeva Lederman, Cathrine Mihalopoulos, Helen Herrman, Cesar Gonzalez-Blanch, Alexandra Parker, Shaminka N Mangelsdorf, Richard M Ryan, Sarah Hetrick, Yong Yi Lee, Greg Murray, Christopher Davey, Virginia Liu, Simon D'Alfonso, Brendan Pawsey, John Gleeson

“…Introduction Major depressive disorder (MDD) causes significant disease burden and functional impairment during adolescence and young adulthood. …”
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In Silico and In Vitro Studies of the Approved Antibiotic Ceftaroline Fosamil and Its Metabolites as Inhibitors of SARS-CoV-2 Replication by Cássia Delgado, Pablo Andrei Nogara, Milene Dias Miranda, Alice Santos Rosa, Vivian Neuza Santos Ferreira, Luisa Tozatto Batista, Thamara Kelcya Fonseca Oliveira, Folorunsho Bright Omage, Flávia Motta, Izabela Marques Bastos, Laura Orian, João Batista Teixeira Rocha

“…<i>In silico</i> analyses (molecular docking and molecular dynamics (MD) simulations) demonstrated that CF and its metabolites are potential inhibitors of PL^pro and M^pro. Docking analysis indicated that the majority of the ligands were more stable with M^pro than PL^pro; however, <i>in vitro</i> biochemical analysis indicated PL^pro as the preferred target for CF. …”
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The gender-sensitive spectrum of neurodevelopmental disorders: a case report on a ZMYM3 variant in a 19-year-old female by Alberto Cordella, Silvia Beatrice Maitz, Daniela Distefano, Marianna Lissi, Lucia Morellini, Leonardo Sacco, Leonardo Sacco, Leonardo Sacco

“…BackgroundNeurodevelopmental disorders (NDDs) such as Intellectual Disability, Autism Spectrum Disorder (ASD), and Attention-Deficit/Hyperactivity Disorder (ADHD) impact cognitive, behavioral, and social functions. The Zinc finger MYM-type protein 3, located on the X-chromosome, has been implicated in neurodevelopment, but its effects in females remain poorly understood due to limited research.Case presentationWe report a 19-year-old female with a de novo heterozygous variant in ZMYM3 (NM_201599.3:c.1927C&gt;G, p.…”
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