TCR-T cell therapy: current development approaches, preclinical evaluation, and perspectives on regulatory challenges by Elena A. Golikova, Alina A. Alshevskaya, Saleh Alrhmoun, Natalia A. Sivitskaya, Sergey V. Sennikov

“…Performed analysis emphasizes the importance of these preclinical stages in the safe and effective development of TCR-T cell therapies. …”
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Impact of Two Hexaploidizations on Distribution, Codon Bias, and Expression of Transcription Factors in Tomato Fruit Ripeness by Yating Han, Wanjie Hu, Xiuling Wu, Xinyu Li, Junxi Luo, Ziying Zhu, Zhenyi Wang, Ying Liu

“…We identified and analyzed eight transcription factor families (TF families) associated with fruit ripening in the genomes of seven tomato species and two outgroup species, revealing the impact of whole-genome duplication (WGD) events on the structure and functional characteristics of these TF families. The results indicate that the Solanaceae Common Hexaploidization (SCH) event is the primary driver for the increase in the number of members within these TF families, leading to a more concentrated chromosomal distribution of family members. …”
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Statistical inference of constant-stress partially accelerated life tests under type II generalized hybrid censored data from Burr III distribution by Hassan Amal S., Alsadat Najwan, Kayid Mohamed, Elgarhy Mohammed, Balogun Oluwafemi Samson, Almetwally Ehab M.

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Health profiles of families with young children: observational study by Inês Fonseca, Vanessa Monteiro, Jóni Madureira, Jacinta Dantas, José Reduto, Zaida Charepe, Henriqueta Figueiredo

“…Results: Five clusters of families were identified, ranging from a more balanced family functioning in cluster 1 to a less balanced functioning in cluster 4, which exhibited the poorest health outcomes, including lower education levels, higher unemployment rates, and worse health perceptions. …”
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An insight into the draft genome of the Oriental rat flea, Xenopsylla cheopis, together with its Wolbachia endosymbiont by Stephen Lu, David M. Bland, Eric Dahlstrom, Neelam Redekar, Melina G. Guizzo, Kent Barbian, B. Joseph Hinnebusch, José M. C. Ribeiro

“…Results Sequencing data from both long and short reads were assembled into 7,694 contigs, from which 95,638 putative coding sequences (CDSs) were extracted and functionally annotated, providing insights into various aspects of flea physiology. …”
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SAFETY OF CANNED MILK AS AN INTEGRATED CRITERION OF THEIR TECHNOLOGY EFFECTIVENESS. RUSSIAN EXPERIENCE by S. N. Turovskaya, A. G. Galstyan, A. N. Petrov, I. A. Radaeva, E. E. Illarionovа, V. K. Semipyatniy, S. A. Khurshudyan

“…However, taking into account the technology development, the expansion of the raw ingredients range, the requirements for the extension of shelf life and much more, the scope of the evaluation criteria for quality and safety indicators is constantly expanding, new methods of a priori and a posteriori analysis are being created, which is fixed in normative and technical documents, that are integrally reflected the level of modern technology. …”
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Coastal Cultural Ecosystem Services: A Bridge between the Natural Ecosystem and Social Ecosystem for Sustainable Development by Yuqing Zhao, Zenglin Han, Changren Zhang, Yuqiao Wang, Jingqiu Zhong, Mengfan Gao

“…Compared to other ecosystems, coastal ecosystems face greater pressures and threats, and the cultural services they provide are more vulnerable. Research on coastal ecosystem cultural services needs to consider ecosystem vulnerability and find ways to protect and restore ecosystem functions. …”
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Evaluation of innovative technology market potential on the basis of technology audit by Oleksandra Kosenko, Victoriia Cherepanova, Iryna Dolyna, Viktoriia Matrosova, Olena Kolotiuk

“…To ensure the efficiency of practical effect of the mechanism proposed, the authors systematized and completed methods of functional analysis and scanning of market environment for the purpose of qualitative comprehensive evaluation and innovative technology market potential forecasting.Introduction of the proposed evaluation method for technology market potential will result in the improvement of efficiency of enterprise innovation activity due to more rational distribution of available resources and immediate financing of developments with greater market potential.…”
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Study on wettability of water stemming for blasting dust adjusted by surfactants and inorganic salts by Fengjie Chen, Zejun Zhou, Ying Liang, Xiaowen Liu, Xiaoguang Wang, Pu Wang, Bolei Chen, Yong Liang, Yawei Wang

“…The two most important components of blasting dust were SiO2 and CaCO3 by characterization analysis. Notably, hydrophilic blasting dust has significantly more SiO2 than hydrophobic blasting dust. …”
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Physics-Informed Learning Framework for Lower Limb Kinematic Prediction With Sparse Sensors and Its Application in Chronic Stroke by Yan Guo, Yusuke Sekiguchi, Wen Zeng, Satoru Ebihara, Dai Owaki, Mitsuhiro Hayashibe

“…Accurate measurement of lower limb joint angles enables therapists to assess the functional status of stroke patients, thereby promoting the rehabilitation process. …”
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STATE BUDGET IN THE CONTEXT OF A WARTIME ECONOMY AND POST-WAR TRIGGERS FOR ITS RECOVERY by Serhii Petrukha, Dmytro Konovalenko, Nina Petrukha

“… The purpose of this study is to systematically analyse the functioning of the state budget of Ukraine in the context of the war economy and identify the key triggers of its post-war recovery. …”
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Chromosome-level genome assembly reveals adaptive evolution of the invasive Amazon sailfin catfish (Pterygoplichthys pardalis) by Yunyun Lv, Yanping Li, Miao Fang, Yi Liu, Yuanyuan Wang, Yexin Yang, Yuanchao Zou, Qiong Shi, Xidong Mu

“…Our analysis shows that the Amazon sailfin catfish genome is notably larger (1.58 Gb) with more than 40,000 coding genes. …”
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An Increase in Academic Ebook Preferences: A Decade Comparison of Ebook Use versus Non-Use by Kathy Grams

“…Other complaints were related to their functionality and usability, such as lag time, clunky interface, accessibility, and challenges with annotation and note-taking. …”
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Efficient spectrally-resolved electron transport for thermal property prediction by Jackson R. Harter, Shuxiang Zhou, Sebastian Schunert, Andrea Jokisaari, P. Alex Greaney

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Broad-spectrum resistance to fungal foliar diseases in wheat: recent efforts and achievements by Amira M. I. Mourad, Amira M. I. Mourad, Asmaa A. M. Ahmed, P. Stephen Baenziger, Andreas Börner, Ahmed Sallam, Ahmed Sallam

“…Furthermore, common genes controlling the resistance of more than one of these foliar diseases were identified. …”
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Synthesis of Side-Chain Liquid Crystalline Polyacrylates with Bridged Stilbene Mesogens by Gen-ichi Konishi, Yuki Sawatari, Riki Iwai, Takuya Tanaka, Yoshimichi Shimomura, Masatoshi Tokita

“…In this work, we synthesized a polyacrylate SCLCP incorporating a bridged stilbene that exhibited a nematic phase near room temperature and could maintain liquid crystallinity for more than three months. We conducted a thorough phase structure analysis and evaluated the optical properties. …”
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Alcohol consumption in patients with cardiovascular diseases (results of the survey of cardiac patients in outpatient practice) by O. D. Ostroumova, I. E. Nikolaeva, S. Ya. Eregin, I. V. Pokrovskaya, K. A. Ishchenko

“…The data of 182 patients (82 women and 100 men, mean age 56.4±5.8 years) was included in the analysis.Results. Arterial hypertension (70%), heart rhythm disorders (25%), ischemic heart disease (20%), functional class I-II chronic heart failure (21%) predominated among all clinical entities. …”
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How Can We Engage Oncology Care Providers and Glioblastoma Patients in Conversations About Physical Activity: A Qualitative Descriptive Study Using the Theoretical Domains Framewor... by Jodi E. Langley, Grace Warner, Christine Cassidy, Robin Urquhart, Mary MacNeil, Melanie R. Keats

“…The data were then analyzed using a directed content analysis using a codebook generated using the TDF. …”
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Interprovincial industrial virtual scarce water flow and water scarcity risk in China by Zhiliang Xu, Changxin Xu, Xueli Chen, Li Yang, Malin Song

“…“Agriculture & Fisheries” typically functioned as the source sector, whereas “Food & Tobacco” and “Construction” served as intermediate or terminal sectors. …”
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Decreased CO2 saturation during circular breathwork supports emergence of altered states of consciousness by Martha N. Havenith, Max Leidenberger, Jelena Brasanac, Mafalda Corvacho, Inês Carmo Figueiredo, Leonie Schwarz, Malin Uthaug, Simona Rakusa, Marijan Bernardic, Liliana Vasquez-Mock, Sergio Pérez Rosal, Robin Carhart-Harris, Stefan M. Gold, Henrik Jungaberle, Andrea Jungaberle

“…Circular breathwork may present a non-pharmacological and hence more accessible alternative to engage similar therapeutic processes. …”
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