Pomalidomide in relapsed and refractory multiple myeloma: multicenter retrospective study by V. G. Potapenko, E. V. Baumert, A. A. Bobrova, R. V. Vashchenkov, N. V. Dorofeeva, K. D. Kaplanov, E. V. Karyagina, A. N. Levanov, A. S. Luchinin, S. I. Moiseev, A. V. Novitskii, A. S. Nizamutdinova, О. V. Pirogova, S. A. Povzun, М. V. Platonov, V. V. Porunova, D. А. Ptashnikov, V. V. Ryabchikova, S. Ya. Simeniv, I. А. Skorokhod, Е. А. Ukrainchenko, D. А. Chaginskaya, T. V. Shelekhova, M. N. Shirokova, A. A. Shutylev, N. V. Medvedeva

“…Kidney impairment at the onset was in 10 (15 %) patients, the normal function was in 57 (85 %) patients and 4 patients had no data. …”
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Vision Restoration through transorbital electrical stimulation in Optic Neuropathy in patients with significant optic atrophy due to primary open-angle glaucoma—a randomised, contr... by Katrin Lorenz, Alexander Radbruch, Hans Hoerauf, Philip Enders, Karl Mercieca, Christian van Oterendorp, Marc Brockmann, Anna Beck, Thomas Asendorf, Bettina Wabbels, Michael Schittkowski, Verena Prokosch, Johanna Pohlner, Carsten Grohmann, Lena Kröger, Jens Haueisen, Alexander Hunold, Maria Bernhard, Peter Dechent, Mathias Bähr, Andrea Antal

“…Introduction Glaucoma is one of the most common causes of blindness and affects more than 70 million people worldwide. The disease is characterised by the loss of retinal ganglion cells associated with a progressive optic neuropathy, resulting in an impairment of visual functions, for example, visual field loss. …”
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Optimizing Nav1.7‐Targeted Analgesics: Revealing Off‐Target Effects of Spider Venom‐Derived Peptide Toxins and Engineering Strategies for Improvement by Sen Luo, Xi Zhou, Meijing Wu, Gongxin Wang, Li Wang, Xujun Feng, Hang Wu, Ren Luo, Minjuan Lu, Junxian Ju, Wenxing Wang, Lei Yuan, Xiaoqing Luo, Dezheng Peng, Li Yang, Qingfeng Zhang, Minzhi Chen, Songping Liang, Xiuming Dong, Guoliang Hao, Yunxiao Zhang, Zhonghua Liu

“…In this study, eight peptide toxins from three distinct spider venom Nav channel families demonstrated robust inhibition of hNav1.7, rKv4.2, and rKv4.3 (rKv4.2/4.3) currents, exhibiting a similar mode of action. The analysis of structure and function relationship revealed a significant overlap in the pharmacophore responsible for inhibiting hNav1.7 and rKv4.2 by HNTX‐III, although Lys25 seems to play a more pivotal role in the inhibition of rKv4.2/4.3. …”
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Long‐Term Prognosis of Ischemic Stroke in Young Adults—A Single‐Center Chinese Cohort Study by Yuhui Sha, Qiqi Wang, Mingyu Tang, Ming Yao, Yicheng Zhu, Lixin Zhou, Jun Ni

“…Main outcomes were recurrent ischemic cerebrovascular events and unfavorable functional outcome (an mRS score ≥ 2). Kaplan–Meier analysis was used to estimate the 5‐year cumulative recurrence risk, and multivariate logistic analysis was used to identify predictors of recurrent ischemic cerebrovascular events and unfavorable functional outcome. …”
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Comparison of conventional, amplitude-integrated and geodesic sensor net EEG used in premature neonates: a systematic review by Tainã Maria Alves de Sousa, Vinicius Siessere Gugelmin, Geraldo Magela Fernandes, Carlos Nogueira Aucélio, Karina Nascimento Costa, Rosana Maria Tristão

“…Conversely, the use of a geodesic sensor net EEG could be of great value, as it allows a large amount of data to be analyzed. Conclusion: This analysis may be useful in studies and research related to diseases and symptoms, such as seizures, a current challenge for neonatal neuromonitoring, as well as aspects of neurological development and functional studies. …”
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Models, systems, networks in economics, engineering, nature and society by E.M. Korostyshevskaya, A.V. Novikov, M.V. Redinskaya

“…A comprehensive historical and logical analysis of the works of Russian and foreign scientists was carried out. …”

Respiration Monitoring Using Humidity Sensor Based on  Hydrothermally Synthesized Two-Dimensional MoS₂ by Gwangsik Hong, Mi Eun Kim, Jun Sik Lee, Ja-Yeon Kim, Min-Ki Kwon

“…Through thermal annealing, the crystal structure of MoS₂ is transformed from 1T@2H to 2H, allowing the measurement of respiration at more than 30 cycles per minute and enabling analysis of the response. …”
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Use of the voxel-based morphometry method in the diagnosis of dementia of the Alzheimer type by E. . Andreev, N. . Ananieva, N. . Zalutskaya, I. A. Beltceva, N. . Neznanov

“…Morphometry of the brain structures using MRI became widespread because of the introduction into clinical practice of a high-resolution mode and the emergence of the voxel transformations of three-dimensional data. The analysis of the brain structures is made more precise with the help of such programs. …”
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Gut dysbiosis is associated with difficult-to-treat rheumatoid arthritis by Patricia Ruiz-Limón, Patricia Ruiz-Limón, Patricia Ruiz-Limón, Natalia Mena-Vázquez, Natalia Mena-Vázquez, Isabel Moreno-Indias, Isabel Moreno-Indias, Isabel Moreno-Indias, Jose Manuel Lisbona-Montañez, Jose Manuel Lisbona-Montañez, Jose Manuel Lisbona-Montañez, Arkaitz Mucientes, Arkaitz Mucientes, Sara Manrique-Arija, Sara Manrique-Arija, Sara Manrique-Arija, Rocío Redondo-Rodriguez, Rocío Redondo-Rodriguez, Laura Cano-García, Laura Cano-García, Francisco J. Tinahones, Francisco J. Tinahones, Francisco J. Tinahones, Francisco J. Tinahones, Antonio Fernández-Nebro, Antonio Fernández-Nebro, Antonio Fernández-Nebro

“…The gut microbiota was analyzed using 16S rRNA gene sequencing; bioinformatics analysis was performed using QIIME2, and its functionality was inferred through PICRUSt. …”
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SERS Sensors with Bio-Derived Substrates Under the Way to Agricultural Monitoring of Pesticide Residues by Kseniya V. Serebrennikova, Nadezhda S. Komova, Anatoly V. Zherdev, Boris B. Dzantiev

“…Common methods of pesticide analysis suffer from high costs, and are time consuming, and labor intensive. …”
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Quality of life of children with epilepsy (neuropsychiatric and social aspects) by O. V. Guzeva, V. I. Guzeva, V. V. Guzeva, I. V. Okhrim, V. R. Kasumov

“…In recent years, a special interest is given to the introduction of neuropsychological methods in studying the brain organization of higher mental functions in children with epilepsy. Analysis of neuropsychological features and characteristics of cognitive disorders with various forms of idiopathic epilepsy is of particular interest.…”
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Assessing High-Order Links in Cardiovascular and Respiratory Networks via Static and Dynamic Information Measures by Gorana Mijatovic, Laura Sparacino, Yuri Antonacci, Michal Javorka, Daniele Marinazzo, Sebastiano Stramaglia, Luca Faes

“…<italic>Goal:</italic> The network representation is becoming increasingly popular for the description of cardiovascular interactions based on the analysis of multiple simultaneously collected variables. …”
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Evaluation of the authenticity of Citri Grandis Exocarpium based on metabolomics and transcriptomics by Haiting Huang, Yu Liu, Jianmu Su, Xiangxiu Liang, Hong Wu, Mei Bai

“…The integrative metabolomics and transcriptomics analysis identified 11 key structural genes and transcription factors potentially involved in flavonoid biosynthesis, providing candidate targets for functional validation. …”
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Cross-feeding-based rational design of a probiotic combination of Bacterides xylanisolvens and Clostridium butyricum therapy for metabolic diseases by Shanshan Qiao, Tao Wang, Jingzu Sun, Junjie Han, Huanqin Dai, Mengxuan Du, Lan Yang, Chun-Jun Guo, Chang Liu, Shuang-Jiang Liu, Hongwei Liu

“…Moreover, the two-strain combinations more effectively restored gut microbial functions by reducing disease-associated pathways and opportunistic pathogen abundance. …”
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Bovine and goat milk fat globule membrane supplementation alleviates autism-like behavior by modulating lipid metabolism and gut microbiota by Rui Guo, Xiao Xiao, Chuanchuan Wang, Tian Yuan, Qianhui Zou, Tian Zhang, Jiarui Liang, Ying He, Zhuo Liu, Xuebo Liu, Shan Wu, Zhigang Liu

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MetaboLINK is a novel algorithm for unveiling cell-specific metabolic pathways in longitudinal datasets by Jared Lichtarge, Gerarda Cappuccio, Gerarda Cappuccio, Soumya Pati, Soumya Pati, Alfred Kwabena Dei-Ampeh, Alfred Kwabena Dei-Ampeh, Senghong Sing, Senghong Sing, Senghong Sing, LiHua Ma, Zhandong Liu, Zhandong Liu, Mirjana Maletic-Savatic, Mirjana Maletic-Savatic, Mirjana Maletic-Savatic

“…IntroductionIn the rapidly advancing field of ‘omics research, there is an increasing demand for sophisticated bioinformatic tools to enable efficient and consistent data analysis. As biological datasets, particularly metabolomics, become larger and more complex, innovative strategies are essential for deciphering the intricate molecular and cellular networks.MethodsWe introduce a pioneering analytical approach that combines Principal Component Analysis (PCA) with Graphical Lasso (GLASSO). …”
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The ClpXP protease and the ClpX unfoldase control virulence, cell division, and autolysis in Streptococcus pneumoniae by Viktor H. Mebus, Supradipta De, Larissa M. Busch, Manuela Gesell Salazar, Rabea Schlüter, Uwe Völker, Sven Hammerschmidt, Dorte Frees

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Low-carbon economic dispatching of integrated energy system based on improved white shark algorithm by LI Haobo, CUI Shuangxi, FAN Weijie

“…Finally, through the simulation and analysis of standard test functions and calculation examples, it is verified that the performance of the improved white shark algorithm is improved in both convergence and population diversity, and the application of the white shark algorithm in the low-carbon economic scheduling problem of integrated energy system can obtain a more low-carbon economic scheduling scheme.…”
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Neurophysiological parameters in patients with hallux valgus by T. K. Verkhozina, E. G. Ippolitova, I. N. Kinash, E. S. Tsyslyak, Ch. Z. Butaev, M. E. Puseva

“…In 10 patients, the parameters of the monosynaptic H-reflex were additionally studied. Analysis of electroneuromyographic parameters in patients with hallux valgus demonstrated a deterioration in the peripheral nerves functioning, which was more pronounced for the tibial nerve (n. tibialis). …”
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A comprehensive psychological study of patients with schizophrenia spectrum disorders by G. G. Lebedeva, A. V. Stepanova, A. P. Kotsubinsky

“…Thus in patients with paranoid schizophrenia cognitive deficit are more pronounced than in patients with schizotypal disorder. …”
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