Epigenome editing of the potential enhancers of the schizophrenia risk genes: approaches for optimization of the genetic constructs by D. A. Abashkin, A. O. Kurishev, S. V. Smirnova, D. S. Karpov, V. E. Golimbet

“…To study in more detail the functions of these genes and the participation of enhancers in their regulation, we obtained plasmid and lentiviral constructs of a functionally active transcription repressor based on the CRISPR / SpyCas9 system, as well as the endonuclease system. …”
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Evaluation of the Morphology and Malachite Green Absorption Capacity of Modified Electrospun Chitosan Nanofibers by Hien Thi Thanh Nguyen, Thao Thi Ngoc Dang, Tan Minh Ha, Nhi Tran Yen Nguyen

“…This result is due to the interaction between the functional group of the polymers that increases entanglement. …”
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Validation of the Brazilian Oral Health Literacy-Adults Questionnaire by Eliete Rodrigues Almeida, Mohammad Mehdi Naghibi Sistani, Cristiane Baccin Bendo, Isabela de Almeida Pordeus, Ramon Targino Firmino, Saul Martins Paiva, Fernanda Morais Ferreira

“…So, the use of comprehensive functional OHL tools is crucial. The Oral Health Literacy-Adults Questionnaire (OHL-AQ) evaluates reading comprehension, numeracy, listening and decision-making skills. …”
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Polyamine metabolism related gene index prediction of prognosis and immunotherapy response in breast cancer by Ruoya Wang, Shouliang Cai, Qing Gao, Yidong Chen, Xue Han, Fangjian Shang, Chunyan Liang, Guolian Zhu, Bo Chen

“…The model successfully stratified BC patients into high-risk and low-risk groups, with the high-risk group exhibiting poorer clinical outcomes. Functional analysis revealed significant differences in immune status and drug sensitivity between high-risk and low-risk groups.ConclusionsThis study elucidated the biological characteristics of PMRG expression subtypes in BC, identifying a polyamine-related prognostic signature and four novel biomarkers to accurately predict prognosis and immunotherapy response in BC patients.…”
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Pathogenomic Insights into <i>Xanthomonas oryzae</i> pv. <i>oryzae</i>’s Resistome, Virulome, and Diversity for Improved Rice Blight Management by Peter Adeolu Adedibu, Oksana Son, Liudmila Tekutyeva, Larissa Balabanova

“…Transposable elements were also discovered to contribute to <i>X. oryzae</i> pathogenicity, facilitating the horizontal transfer of virulence genes. Pangenome analysis revealed intraspecific variation among the population, with 112 unique CDS having diverse functional roles. …”
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A hybrid workflow connecting a network and an agent-based model for predictive pedestrian movement modelling by Anita Ullrich, Franziska Hunger, Ioanna Stavroulaki, Adam Bilock, Klas Jareteg, Yury Tarakanov, Alexander Gösta, Alexander Gösta, Johannes Quist, Meta Berghauser Pont, Fredrik Edelvik

“…Pedestrian movement has always been one of the main concerns for urban planning and design, but it has become more important within the sustainable development agenda, as walking is crucial to reducing urban emissions and fostering liveable cities. …”
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Urban development and natural public spaces in Daloa, West Central Côte d'Ivoire by Kinakpefan Michel TRAORE, Atsé Laudose Miguel ELEAZARUS, Mangoua Akissi Hélène-Francette KOUASSI

“…A fundamental element in the creation of the green city, urban nature in the city of Daloa is more a question of unfinished urbanisation than of proactive, structuring development. …”
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Association of admission blood glucose and postoperation fast blood glucose with futile recanalization in patients with endovascular therapy by Dandan Chen, Yunqing Chen, Linghong Guo, Zubing Xu, Xian Liu, Xilin Xiong, Hudie Zhang, Yan Gong, Qiulong Yu, Chenying Zeng, Lanjiao Zhang, Qin Huang, Jinchong Zhang, Keji Zou, Xiaobing Li, Daojun Hong, Pu Fang, Jing Lin

“…Abstract Background Futile recanalization (FR), defined as patients with long-term functional dependence despite successful recanalization, is common in patients with large-vessel stroke undergoing endovascular treatment (EVT). …”
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Landscape Ecological Integrity Assessment to Improve Protected Area Management of Forest Ecosystem by Mingquan Yu, Yizhen Liu

“…The landscape fragmentation analysis for the important landscape types in all functional zones showed that the experimental zone and the buffer zone were relatively more severe than the core zone; the core area was lighter with minimal anthropogenic impacts and the most complete protection of the nature reserve. …”
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Effect of adsorption and drying on the physicochemical properties and thermal stability of collagen peptide powders derived from Cannonball jellyfish (Stomolophus meleagris) by Javier Cruz-Padilla, Vondel Reyes, Jinru Chen, James Gratzek, Joseph G. Usack, Jason Locklin, Adaeze Osakwe, Zachary Cartwright, Kevin Mis Solval

“…SD powders were drier, smaller, more uniform with extended shelf life than FD powders. …”
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Application Models and Innovative Approaches of Smart Libraries from the Perspective of MR Technology by Jiaxin HUANG, Xiaofang ZHANG

“…[Method/Process] By using the methods of literature review, content analysis and website analysis, this paper reviews the current research status of MR Technology in the field of library science at home and abroad. …”
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Computational advances in the design and discovery of artemis inhibitors for radiosensitization in cancer therapy by Maryam Bashir, Usman Abdullah, Sadia Nazir, Farhan Siddique, Nasir Jalal

“…The integrated in vitro and computational findings offer a foundation for further preclinical development, contributing to more effective radiotherapy strategies in cancer treatment.…”
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Sport commitment among children and adolescent through the lens of theory of organismic integration: A systematic literature review by Anna Pavlova

“…For a more detailed study, 22 publications were selected, which allowed us to validate the theoretical framework of this paper. …”
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Aloin protects against UVB-induced apoptosis by modulating integrated signaling pathways by Qi He, Yu-Pei Chen, Yu-Pei Chen, Yu-Pei Chen, Chun Wu, Hongtan Wu, Hongtan Wu, Fei Li, Fei Li, Mingyu Li, Fangfang Chen, Fangfang Chen

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Impacts of Low-Order Stream Connectivity Restoration Projects on Aquatic Habitat and Fish Diversity by Xinfeng Li, Xuan Che, Xiaolong Chen, Changfeng Tian, Jiahua Zhang

“…However, existing research predominantly focuses on large dams in primary rivers, overlooking the more severe fragmentation caused by low-head barriers within low-order streams. …”
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Genomic features, antimicrobial resistance and pathogenicity assessment of Escherichia coli serotype O177:H51 strain JS01 isolated from a diseased chicken by Lunbin Xia, Guanglei Wang, Naidong Chen, Deliang Qiao, Jianwen Cao, Shaoshuai Bi

“…To elucidate its multi-drug resistance and pathogenic mechanisms, whole-genome sequencing (WGS) of JS01 was performed, followed by functional gene annotation, sequence typing, and serotype analysis. …”
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Revisiting Cosa (Ansedonia, Italy): contributions of SAR-X images from the PAZ satellite to non-invasive archaeological prospecting by José Ignacio Fiz Fernández, Pere Manel Martín Serrano, Maria Mercè Grau Salvat, Antoni Cartes Reverté

“… • The study has been completed with the analysis of multispectral images TripleSAT and Sentinel-2A and the historical aerial photos from 1944 and 1954…”
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Mucosal microbiota signatures reveal diagnostic insights in chronic liver disease by Sadık Dinçer, Yakup Ülger, Anıl Delik

“…The intestinal microbiota acts as a bioreactor for autonomous metabolic and immunological functions in regulating the host’s response to external stimuli in the intestinal microbiota. …”
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Cation-induced topical disordered niobium nickel oxide for robust hydrogen storage in magnesium hydride by Shuai Li, Liuting Zhang, Fuying Wu, Qian Li

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The predictive utility of the E-PASS score for postoperative complications in robot-assisted partial nephrectomy: a retrospective cohort study by Cagatay Ozsoy, Erhan Ates, Resat Inal, Mucahit Gelmis, Sahin Kilic, Mutlu Ates

“…Abstract Background Robot-assisted partial nephrectomy (RAPN) is widely used for small renal tumors and provides favorable oncological and functional outcomes. However, a significant risk of postoperative complications remains a concern. …”
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