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Telomerase activity in T-cells as a functional test for pathogenicity assessment of novel genetic variants in telomere biology disorders
Published 2025-08-01“…In summary, functional analysis of TA in patient-derived cells could support pathogenic evaluation in clinical diagnostics and reduce the number of reported VUS for TBD patients.…”
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Structural-Functional Analysis of the Rural Housing Using Sustainable Development Approach (Case Study: in Eastern Roumeshkhan County, Kuhdasht township)
Published 2018-09-01“…The purpose of the study is the dwellings’ structural and functional conformity by considering sustainable development indicators in eastern Rumeshkhan county, Lorestan province. …”
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The relationship between social isolation and cognitive function in older patients with chronic obstructive pulmonary disease: a latent profile analysis
Published 2025-07-01“…Patients with low education levels and annual household income per capital between 7000 and 15,000 Yuan were more likely to belong to the “Moderate Social Isolation-Moderate Interaction Group”. …”
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406
The effectiveness of various computer-based interventions for patients with chronic pain or functional somatic syndromes: A systematic review and meta-analysis.
Published 2018-01-01“…Pooled standardized mean differences by comparison type, and somatic symptom, health-related quality of life, functional interference, catastrophizing, and depression outcomes were calculated at post-treatment and at 6 or more months follow-up. …”
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Differential effects of obesity and hypertension on brain structure and cognitive ability: A subgroup analysis from nested study
Published 2025-07-01“…Background: Obesity and hypertension are widespread health issues associated with changes in brain structure and cognitive function, especially in individuals who lead sedentary lifestyles. …”
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Urinary phytoestrogen levels and reduced thyroid hormone sensitivity: a cross-sectional analysis of NHANES 2007–2010
Published 2025-07-01“…Results The final analysis included 2521 euthyroid participants. After weighted multivariable adjustment (excluding dietary patterns and serum iodine levels), urinary phytoestrogen concentrations showed significant sex- and compound-specific associations with both thyroid function indicators and thyroid hormone sensitivity indices. …”
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413
Stochastic Fracture Analysis Using Scaled Boundary Finite Element Methods Accelerated by Proper Orthogonal Decomposition and Radial Basis Functions
Published 2021-01-01“…This paper presents a stochastic analysis method for linear elastic fracture mechanics using the Monte Carlo simulations (MCs) and the scaled boundary finite element method (SBFEM) based on proper orthogonal decomposition (POD) and radial basis functions (RBF). …”
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414
Cognitive-behavioral therapy for the improvement of negative symptoms and functioning in schizophrenia: A systematic review and meta-analysis of randomized controlled trials.
Published 2025-01-01“…This study aims to conduct a meta-analysis to assess the effects of CBT on negative symptoms and function in schizophrenia.…”
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Genome-wide identification of five fern bHLH families and functional analysis of bHLHs in lignin biosynthesis in Alsophila spinulosa
Published 2025-04-01“…Tandem duplications were key to bHLH gene diversity in C. richardii, A. capillus, and A. spinulosa, while segmental duplications contributed more to bHLH gene expansion in A. spinulosa. Evolutionary analysis indicated most fern bHLH genes are under purifying selection. …”
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Illness (self) management, clinical and functional recovery as determinants of personal recovery in people with severe mental illnesses: A mediation analysis.
Published 2024-01-01“…The results showed that the improvement in overall illness management was directly associated with improvements in personal recovery (B = .30), and indirectly through improvements in clinical recovery (indirect effect = .13) and functional recovery (indirect effect = .08). The main conclusion is that self-reported illness management appears to be more strongly and directly associated with personal recovery than indirectly via clinical and functional recovery. …”
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Efficacy of a brief online intervention in reducing excessive worry and improving daily functioning: A randomized trial with mediation analysis
Published 2025-09-01“…Excessive worry is common among treatment-seeking individuals in primary care and has a negative impact on daily functioning, which may also lead to other mental health problems. …”
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Effectiveness of Computerized and Traditional Cognitive Interventions in improving the Cognitive Functions of Iranian Older Adults: A Systematic Review and Meta-Analysis
Published 2025-06-01“…Also, the subgroup analysis results showed that computerized cognitive interventions were slightly more effective than traditional cognitive interventions. …”
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