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2661
When DNA Repair Backfires – Trabectedin Induces DNA Breaks in Active Genes
Published 2025-04-01“…Many anticancer drugs are ineffective in tumors that have functional DNA repair mechanisms. In contrast, trabectedin, a tetrahydroisoquinoline alkaloid marine natural product, stands out as it is more lethal to cancer cells with active DNA repair, particularly transcription-coupled nucleotide excision repair (TC-NER), making it an intriguing alternative to standard chemotherapeutic agents. …”
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2662
Gut microbiome-derived bacterial extracellular vesicles in patients with solid tumours
Published 2025-02-01“…Metadata classification of samples was more accurate using fecal bEVs (100%) compared with fecal samples (93%). …”
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2663
Turning a polystyrene microsphere into a multimode light source by laser irradiation
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2664
Enhancing the Energy Content of Melawan Coal through H<sub>2</sub>SO<sub>4</sub> and NaOH Demineralization
Published 2025-05-01“…The removal of mineral impurities can lead to a higher calorific value, making coal more suitable for energy generation applications.…”
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2665
Construction of an artificial zinc alloy layer toward stable zinc-metal anode
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2666
An efficient strategy to promote food waste composting by adding black soldier fly (Hermetia illucens) larvae during the compost maturation phase
Published 2024-12-01“…The increasing generation of food waste (FW) poses a significant challenge to global food security and environmental sustainability. …”
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2667
Understanding the moderating role of chronotypes for online mobile gaming in-app purchase intention
Published 2024-09-01“…From a practitioners’ perspective, the present study highlighted a loyal segment of gamers who is more inclined to make in-app purchases. In addition, it highlights a dilemma for gaming operators to balance revenue generation with the well-being of its clientele.…”
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2668
Inter-Calibration and Limb Correction of FY-3D/E MWTS for Long-Term Gridded Microwave Brightness Temperature Dataset
Published 2025-01-01“…The Microwave Temperature Sounder-3 (MWTS-3) onboard the Chinese FengYun-3E (FY-3E) satellite is the third generation of Chinese microwave temperature sounder. …”
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2669
Multivalent ionizable lipid-polypeptides for tumor-confined mRNA transfection
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2670
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2671
Comparative analysis of metaheuristic load balancing algorithms for efficient load balancing in cloud computing
Published 2023-06-01“…Therefore it requires more time to predict the best possible solution. …”
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2672
Mutational Analysis of Extranodal NK/T-Cell Lymphoma Using Targeted Sequencing with a Comprehensive Cancer Panel
Published 2016-09-01“…The recent technological advancements in next-generation sequencing (NGS) have made DNA sequencing cost- and time-effective, with more reliable results. …”
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2673
A Comprehensive Review of Sulfide Solid-State Electrolytes: Properties, Synthesis, Applications, and Challenges
Published 2025-05-01“…To address these concerns and enhance energy density, all-solid-state batteries (ASSBs) have emerged as a safer and more efficient alternative to conventional liquid electrolyte-based systems. …”
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2674
Artificial intelligence enabled smart design and manufacturing of advanced materials: The endless Frontier in AI+ era
Published 2024-09-01“…Finally, more duties are called to educate the next generation workforce with creative minds and skills. …”
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2675
Technological enhancements in personalized dietary management for chronic conditions
Published 2025-11-01“…This review provides an overview of the strengths and limitations of these approaches in real world applications, as well as emerging methodologies that attempt to improve this by focusing on means to personalize dietary management more effectively. The study suggests that technology-enabled dietary interventions can be useful to support chronic disease management and generative artificial intelligence may have a profound effect on the further personalization of dietary guidance. …”
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Induction of tissue resident memory T cells by measles vaccine vector
Published 2024-12-01“…The intranasal route induced more Trm in the lungs than other routes, confirming the potential of intranasal vaccine administration of replicative viral vectors to generate a strong pulmonary immune response. …”
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Performance and Secrecy Analysis of Cooperative Full-Duplex NOMA System With Fountain Codes and Intelligent Reflective Surface
Published 2025-01-01“…Intelligent Reflective Surfaces (IRSs) are recognized as fundamental technology in the context of the forthcoming sixth-generation (6G) communication systems. Non-Orthogonal Multiple Access (NOMA) can augment fifth-generation (5G) wireless networks’ spectral efficiency. …”
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Revolutionizing pharmacology: AI-powered approaches in molecular modeling and ADMET prediction
Published 2025-12-01“…The convergence of AI with quantum chemistry and density functional theory (DFT) is illustrated through surrogate modeling and reaction mechanism prediction. …”
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Epigenomic and 3D genomic mapping reveals developmental dynamics and subgenomic asymmetry of transcriptional regulatory architecture in allotetraploid cotton
Published 2024-12-01“…We systematically identify a subset of genes that are closely associated with specific tissue functions. Interestingly, these genes exhibit not only higher tissue specificity but also a more pronounced homoeologous bias. …”
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