Computational design and cheminformatics profiling of omeprazole derivatives for enhanced proton pump inhibition of potassium-transporting ATPase alpha chain 1. by Mahmudul Hasan, Md Ifteker Hossain, Noimul Hasan Siddiquee, Ezaz Ahmed, Md Walid Hossain Talukder, Md Rahamatolla, Tasrin Nahar, Popy Rani Paul, Mahmudul Hassan Suhag, Monir Uzzaman

“…These findings could lead to the development of OMP3 and OMP21 as potential next-generation PPIs with enhanced pharmacological activity and improved side-effect profiles, necessitating more in vitro and in vivo testing.…”
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Risk assessment in ensuring aircraft on-board systems safety by H. E. Fourar, B. D. Ogunvoul, V. D. Budaev, F. Lachi

“…However, the method proposed in this article intends to become a catalyst for generation of new criteria on a unified basis for estimating safety of such a technical complex system such as AIS, since it contains three-component risk parameters. …”
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AI‐Based Ensemble Flood Forecasts and Its Implementation in Multi‐Objective Robust Optimization Operation for Reservoir Flood Control by Yuxue Guo, Yue‐Ping Xu, Xinting Yu, Li Liu, Haiting Gu

“…MRO released more inflow than TSO, decreasing the expected highest water level by 0.05 m and incrementing the expected peak release by 4.29%. …”
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Analgesic effect of simultaneously targeting multiple pain processing brain circuits in an aged humanized mouse model of chronic pain by transcranial focused ultrasound by Min Gon Kim, Chih-Yu Yeh, Kai Yu, Zherui Li, Kalpna Gupta, Bin He

“…We developed and evaluated the performance of the UAFE capable of generating sufficiently high-amplitude output with significantly lower noise levels compared to a commercial transmitter. …”
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Soluble human macrophage factors are able to inhibit TGF-β-induced differentiation of lung fibroblasts by A. A. Maksimova, E. Ya. Shevela, L. V. Sakhno

“…On day 5, dexamethasone was added to generation of polarized macrophages M-M(Dex) and GM-M(Dex). …”
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Green synthesis and evaluation of the anticancer potency of Ag, Cuo, and Ag/Cuo nanoparticles synthesized using Searsia lancea fruit extract by Dineo Majoang, Mercy C. Ogwuegbu, Doctor M.N. Mthiyane, Moganavelli Singh, Damian C. Onwudiwe

“…This enhanced activity is attributed to the generation of reactive oxygen species (ROS) and their synergistic interactions, inducing oxidative stress and apoptosis in cancer cells. …”
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Feasibility and acceptability for LION, a fully remote, randomized clinical trial within the VA for light therapy to improve sleep in Veterans with and without TBI: An MTBI2 sponso... by Jonathan E Elliott, Jessica S Brewer, Allison T Keil, Brittany R Ligman, Mohini D Bryant-Ekstrand, Alisha A McBride, Katherine Powers, Savanah J Sicard, Elizabeth W Twamley, Maya E O'Neil, Andrea D Hildebrand, Thuan Nguyen, Benjamin J Morasco, Jessica M Gill, Bradley A Dengler, Miranda M Lim

“…These TBI-related sleep impairments confer significant burden and commonly exacerbate other functional impairments. Therapies to improve sleep following mTBI are limited and studies in Veterans are even more scarce. …”
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Raster Image-Based House-Type Recognition and Three-Dimensional Reconstruction Technology by Jianbo Chang, Yunlei Lv, Jian Wang, Hao Pang, Yaqiu Liu

“…Three-dimensional models reconstructed from two-dimensional floor plans provide more intuitive visualization for building safety assessments and spatial suitability evaluations. …”
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Mechanism of Population Outflow and Ecological Pressure Reflux in China’s Pastoral Area: S-C Gacha’s Case by Mingming Fan, Gongbu Zeren

“…The “three-separating property right systems”, a recent rural land institutional reform policy, has marketized rural individualized rangelands, leading herders to focus more on the exchange value of rangelands rather than the use value, including ecological functions. …”
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NATIONAL QUALIFICATIONS FRAMEWORKS: CONCEPTUAL AND METHODOLOGICAL PRINCIPLES IN THE CONTEXT OF UNRESOLVED ISSUES by O N. Oleynikova, A. A. Muravyeva, N. M. Aksenova

“…The deficiency of highly skilled professionals meeting the requirements of the modern labour market has become the reason for search of new, more effective regulation mechanisms of vocational training and personnel certification for post-industrial knowledge-based economy. …”
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Bioenergy potential of Chlorella vulgaris under the influence of different light conditions in a bubble column photobioreactor by S. Dhanasekar, R. Sathyanathan

“…Fourier transform infrared spectroscopy was used to illustrate the functional group of microalgae under different lighting conditions. …”
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Impeding Quorum Sensing Among the Intestinal Microbiota Impacts the Metastatic Rate of Colorectal Cancer by Matthew Dietz, Travis J. Gates, Rakesh Sikdar, Subbaya Subramanian, Mikael H. Elias, Christopher Staley

“…Fecal samples were collected weekly and characterized by Illumina next‐generation sequencing, with tissues collected during necropsy. …”
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A data-mining analysis of host solute carrier family proteins in SARS-CoV-2 infection with reference to brain endothelial cells and the blood-brain barrier in COVID-19 by Talia Fradkin, Rainald Schmidt-Kastner

“…Literature searches for host SLCs revealed involvement of a subset of SLCs in infection mechanisms for SARS-CoV-2 and more broadly for other viruses. N = 17 host ABCs were found in brain endothelial cells where they may serve as efflux transporters.DiscussionThis hypothesis-generating work proposes a set of N = 80 host SLCs expressed in endothelial cells as contributors to BBB impairment after SARS-CoV-2 infection. …”
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Theory-Driven EEG Indexes for Tracking Motor Recovery and Predicting the Effects of Hybridizing tDCS With Mirror Therapy in Stroke Patients by Chia-Lun Liu, Ken-Hsien Su, Yi-Shiung Horng, Chia-Ling Chen, Shou-Hsien Huang, Ching-Yi Wu

“…The EEG indexes used in this study focused on the functional involvement for motor generation: alpha power at temporal regions (inhibiting non-motor activity) and central-frontal regions (releasing motor regions from inhibition). …”
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MOG-specific CAR Tregs: a novel approach to treat multiple sclerosis by Jihane Frikeche, Marion David, Xavier Mouska, Damien Treguer, Yue Cui, Sandrine Rouquier, Enora Lecorgne, Emma Proics, Papa Babacar Fall, Audrey Lafon, Gregory Lara, Alexandra Menardi, David Fenard, Tobias Abel, Julie Gertner-Dardenne, Maurus de la Rosa, Celine Dumont

“…While several disease-modifying therapies are available to treat MS, these therapies are not universally effective and do not stop disease progression. More personalized long-term treatment options that target specific aspects of the disease, such as reducing relapse frequency, delaying disability accumulation, and addressing symptoms that impact daily functioning, as well as therapies that can promote neuroprotection and repair are needed. …”
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Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases by Jörg T Regula, Peter Lundh von Leithner, Richard Foxton, Veluchamy A Barathi, Chui Ming Gemmy Cheung, Sai Bo Bo Tun, Yeo Sia Wey, Daiju Iwata, Miroslav Dostalek, Jörg Moelleken, Kay G Stubenrauch, Everson Nogoceke, Gabriella Widmer, Pamela Strassburger, Michael J Koss, Christian Klein, David T Shima, Guido Hartmann

“…These properties make RG7716 a potential next‐generation therapy for neovascular indications of the eye.…”
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Enhanced Control of Single Crystalline Ag Dendritic Growth on Al Foil via Galvanic Displacement and Simultaneous Oxidation of D‐Glucose by Lidija D. Rafailović, Stefan M. Noisternig, Jana Bischoff, Christian Rentenberger, Daniel Bautista – Anguis, Huaping Sheng, Christoph Gammer, Jia Min Chin, Adam Elbataioui, Huanqing Zhang, Jürgen Eckert, Tomislav Lj. Trišović

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LABORATORY STUDY OF POLYMERIZATION DEPTH OF COMPOSITE MATERIALS by O.A. Udod, Kh.I. Bekuzarova

“… With the advent of modern improved restorative materials, the process of teeth restoration has become even more complex, but it provides an impeccable anatomical, functional and aesthetic result. …”
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Unraveling the potential of microbial diversity in pesticide remediation: An eco-friendly approach for environmental sustainability by Adhi Singh, Kailash Chand Kumawat

“…Their subsequent use in contemporary agriculture for pesticides breakdown highlights the need of promoting pesticide stress tolerance. The functions of soil-dwelling PGPR's in reducing pesticide stress, the supply of nutrients (nitrogen fixation and phosphorus solubilization), the generation of phytohormones, and the variables that may significantly impact their efficacy. …”
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Molecular mechanisms of leukemogenesis by D. A. Domninskiy

“…Modern medicine is on the verge of the emergence of a large number of new generation drugs whose activity is aimed at modulating (activating or suppressing) the functions of certain target molecules that are involved in the processes of leukemia. …”
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