Unités Paysagères et services écosystémiques, l’exemple des récifs coralliens by Gilbert David, Émilie Mirault, Gwenaëlle Pennober, Christophe Révillion

“…Thus the reef is not only a natural capital but also a landscape composed of associated resources spaces generating specific ecosystem services. But the finance orientated trend for valuing the environment makes more and more weak this cross cutting view and drives to a deadlock. …”
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A meta-analysis of epigenome-wide association studies of ultra-processed food consumption with DNA methylation in European children by Joana Llauradó-Pont, Nikos Stratakis, Giovanni Fiorito, Evangelos Handakas, Alexander Neumann, Henrique Barros, Anne Lise Brantsæter, Kiara Chang, Leda Chatzi, Janine F. Felix, Regina Grazuleviciene, Vincent W. V. Jaddoe, Marianna Karachaliou, Marion Lecorguillé, Carla Lopes, Christopher Millett, Rosemary R. C. McEachan, Eleni Papadopoulou, Remy Slama, Eszter P. Vamos, Paolo Vineis, Martine Vrijheid, John Wright, Trudy Voortman, Mariona Bustamante, Oliver Robinson, Camille Lassale

“…Methods We conducted a meta-analysis of epigenome-wide association studies (EWAS) from a total of 3152 children aged 5–11 years from four European studies (HELIX, Generation XXI, ALSPAC, and Generation R). UPF consumption was defined applying the Nova food classification system (group 4), and DNA methylation was measured in blood with Illumina Infinium Methylation arrays. …”
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The Ethical Significance of Brain-Computer Interfaces as Enablers of Communication by Toma Gruica

“…Much of the public discourse surrounding BCIs has centered on high-profile commercial ventures—such as Elon Musk’s Neuralink—and the controversies these projects generate. These controversies include the ethics of animal testing protocols, speculative claims regarding human enhancement and human-AI symbiosis, and the broader societal implications of merging minds with machines.[1] While these debates are significant, there is a more fundamental ethical dimension inherent to BCIs. …”
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Grown up in the face of values. The subjective dimension of shaping values in human life. by Rafał Bodarski

“…Man, therefore, as a structure capable of managing itself, generating changes in the environment thanks to internal motivation. …”
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Inference of Impulse Responses via Bayesian Graphical Structural VAR Models by Daniel Felix Ahelegbey

“…Impulse response functions (IRFs) are crucial for analyzing the dynamic interactions of macroeconomic variables in vector autoregressive (VAR) models. …”
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An optimized integrin α6-targeted peptide capable of delivering toxins for melanoma treatment by Zheng Zhao, Zi-Qian Li, Ying-Bin Huang, Meng-meng Liu, Fei Cao, Guo-Long Bu, Peng-Fei Xu, Qi Fang, Zhu-Long Hu, Di Wu, Guo-Kai Feng, Xue-Kui Liu

“…Moreover, 4S5NG-incorporated Pseudomonas aeruginosa (PE24) exotoxin A generated therapeutic peptides. The antitumor efficacy and underlying mechanism were studied in cell lines and a mouse model. …”
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Novel trispecific killer engager targeting B7-H3 enhances natural killer cell antitumor activity against head and neck cancer by Jeffrey S Miller, Martin Felices, Peter Hinderlie, James Lim, Naomi Fujioka, Shee Kwan Phung, Yvette Soignier, Joshua T Walker, Melissa A Geller, Madison Shackelford, Carly Selleck, Philippa R Kennedy, Mihir Shetty, Melissa J Khaw, Paolo P Provenzano, Nicholas A Zorko, Laura E Bendzick, Riley C Lyons, Elise L Femino, Terran Stenger, Tumpa Dasgupta, Laura E Kotz, Eng Hock Lee, Quynhanh Lu, Zachary B Davis, John E Wagner, Margaret L MacMillan

“…This TriKE is comprised of a camelid nanobody that binds to CD16 on NK cells, an interleukin (IL)-15 moiety, and another novel camelid nanobody that binds to the B7-H3 antigen, which is highly and specifically expressed on the tumor cell surface.Methods The B7H3 TriKE was generated using a mammalian expression system. Its functionality was evaluated using flow cytometry-based NK cell degranulation, cytokine production, proliferation and live cell imaging cytotoxicity assays. …”
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Reaching new frontiers in nanoelectronics through artificial intelligence by Santhosh Sivasubramani, Themis Prodromakis

“…Recent advances in generative AI models have particularly accelerated innovation, enabling more efficient execution of complex tasks such as drug discovery, autonomous driving, and predictive maintenance. …”
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Cell-Type-Specific Heat-Induced Changes in the Proteomes of Pollen Mother Cells and Microspores Provide New Insights into Tomato Pollen Production Under Elevated Temperature by Priya Thapa, Jun Guo, Kajol Pradhan, Dibya Thapa, Sudhakar Madhavarapu, Jing Zou, Jesse Potts, Hui Li, Joshua O’Hair, Chen Wang, Suping Zhou, Yong Yang, Tara Fish, Theodore W. Thannhauser

“…These HS-induced DAPs include proteases, antioxidant proteins, and proteins related to cell wall remodeling and the generation of pollen exine. Conclusions: HS induced more dynamic proteomic changes in meiotic PMCs compared to microspores, and the inter-varietal differences in the PMC proteomes align with the effects of HS on pollen productivity observed in the two varieties. …”
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Cacao Agroforestry in Mahakam Ulu: Transformation Strategy from Traditional to Good Agricultural Practices and Smart Agroforestry System by Catur Budi Wiati, Eddy Mangopo Angi, Karmilasanti Karmilasanti, Murniati Murniati, Sri Suharti, Indra A.S.L.P. Putri, Aris Pudji Hadi, Muhammad Furkan, Belasius Anyeq, Krista Tala, Veronica Carolina, Awaluddin Aziz, Ria Andiana, Yuliara Limbong, Yosua Naibaho, Mukrimin Mukrimin

“… The Dayak community in East Kalimantan is renowned for practicing traditional Agroforestry (AF) across generations. Meanwhile, despite the long-term introduction of cacao (Theobroma cacao) in 1996 as a potential commodity in the AF practice, its productivity still needs to be improved. …”
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Real-world validation of safe reinforcement learning, model predictive control and decision tree-based home energy management systems by Julian Ruddick, Glenn Ceusters, Gilles Van Kriekinge, Evgenii Genov, Cedric De Cauwer, Thierry Coosemans, Maarten Messagie

“…Recent advancements in machine learning based energy management approaches, specifically reinforcement learning with a safety layer (OptLayerPolicy) and a metaheuristic algorithm generating a decision tree control policy (TreeC), have shown promise. …”
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Development mechanism and practical significance of deep coalbed methane (coal rock gas) infiltration and displacement by Lihong ZHOU, Xia YAN, Hongtao LIU, Xianyue XIONG, Feng WANG, Shuguang LI, Jiyuan ZHANG, Chuanqing LIU, Xiong HU, Pu YUAN, Qianli MA, Xueguang ZHU

“…For 2 nm pores under reservoir and post-fracturing pressure conditions, strong hydrophilic (30° contact angle) and weakly hydrophilic (70°) pores generated capillary forces exceeding 40.1 MPa and 15.8 MPa, respectively, creating intense imbibition driving forces. …”
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Advances on whole genome sequencing in Triticeae by KUANG Liuhui, LI Qi, ZHANG Guoping

“…With the rapid development of third-generation long read sequencing technologies and assembly algorithms designed for complex genomes, and also the falling cost of genome sequencing in recent years, more and more Triticeae species have been successfully sequenced. …”
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Multi-Robot Navigation System Design Based on Proximal Policy Optimization Algorithm by Ching-Chang Wong, Kun-Duo Weng, Bo-Yun Yu

“…The system consists of a localization unit, an environment map unit, a path planning unit, and an environment monitoring unit, which provides functions for calculating robot coordinates, generating preselected paths, selecting optimal path combinations, robot navigation, and environment monitoring. …”
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Root cause analysis of noise transfer in an entire tractor system using multi-layer operational transfer path analysis by Hyun-Woo Han, Min-Woo Kang, Seong-Hyun Lee, Yun-Ho Seo, Seung-Je Cho, Jeong-Gil Kim, Young-Joo Kim, Young-Jun Park

“…Electric-powered next-generation tractor systems lack masking effects in engines. …”
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Effect of <i>Paulownia</i> and Buckwheat Intercropping on Soil Microbial Biodiversity, Dehydrogenase Activity, and Glomalin-Related Soil Protein by Małgorzata Woźniak, Marek Liszewski, Anna Jama-Rodzeńska, Elżbieta Gębarowska, Sylwia Siebielec, Agata Kaczmarek, Bernard Gałka, Dariusz Zalewski, Przemysław Bąbelewski

“…This study shows that tree-based intercropping (TBI) systems promote a more diverse soil microbial community and function than conventional agriculture. …”
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The Coaching for Cognition in Alzheimer's (COCOA) trial: Study design by Jared C. Roach, Junko Hara, Deborah Fridman, Jennifer C. Lovejoy, Kathleen Jade, Laura Heim, Rachel Romansik, Adrienne Swietlikowski, Sheree Phillips, Molly K. Rapozo, Maria A. Shay, Dan Fischer, Cory Funk, Lauren Dill, Michael Brant‐Zawadzki, Leroy Hood, William R. Shankle

“…Secondary outcome measures include the Functional Assessment Staging Test (FAST), a measure of function. …”
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ICOS-expressing CAR-T cells mediate durable eradication of triple-negative breast cancer and metastasis by Hui Zhang, Fei Yu, Xinxin Chen, Haiyan Ye, Tao Zeng, Lixue Cao, Haojie Peng, Yanzhen Chen, Baijin Xia, Jialing Guo

“…We developed ICOS-enhanced B7H3-CAR-T cells (ICOS-B7H3-CAR) using the third-generation CAR-T cell technology, which featured magnified ICOS expression and targeted the B7H3 antigen. …”
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Preliminary evaluation of a mindfulness intervention program in women with long COVID dysautonomia symptoms by Elizabeth Vandenbogaart, Matthew Figueroa, Diana Winston, Steve Cole, Julienne Bower, Jeffrey J. Hsu

“…The effects on conserved transcriptional response to adversity (CTRA) were examined by next-generation sequencing of dried whole blood samples. …”
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The role of mitochondria in the ischemic-reperfusion damage of the brain in operations on aortal arch in conditions of experiment by S. M. Gramatiuk, Yu. V. Ivanova, V. I. Kravchenko, O. O. Lohvinenko

“…In environment of ischemia/reperfusion of the brain in its cells a significant disorders of mitochondrial function occur, which are demonstrated by raising of generation of the oxygen active forms, and by lowering of transmembranous mitochondrial potential and velocity of mitochondrial respiration by 40%, what is accompanied by development of lactate-acidosis. …”
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