Biochemical factors in the blood serum of neuroendocrine tumor patients with carcinoid syndrome by N. V. Lyubimova, Yu. S. Timofeev, A. V. Lebedeva, A. V. Artamonova, I. S. Stilidi, N. E. Kushlinskii

“…Carcinoid syndrome is the most common functional syndrome in patients with neuroendocrine tumors. …”
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Clinical significance and prognostic value of SIRT1 genetic variants in sepsis: a multicenter hospital-based case–control study by Junbing He, Meiting Yang, Yao Lin, Wanbing Qin, Ruoxuan Yang, Yuting Qin, Lizhen Liu, Mingwei Xu, Yiming Shao, Qinghua Liu

“…Conclusions The current research has yielded significant clinical evidence indicating that the SIRT1 rs4746720 and rs12778366 polymorphisms serve as functional variants with potential utility as prognostic markers for sepsis progression. …”
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Effects of smoking on the level of sp-a and sp-d surfactant proteins in the blood of patients without bronchopulmonary diseases by O. S. Kharlamovа, K. Yu. Nikolaev, Yu. I. Ragino, M. I. Voevoda

“…All patients underwent clinical, functional, diagnostic and laboratory tests. The content of surfactant proteins SP-A and SP-D in the blood was determined by enzyme immunoassay.Results. …”
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Effect of Static Balance Ability on Dual-Task Costs Under Different Walking TaskInterventions in Chinese Older Adults by WANG Chenglong, NIE Mingjian, XIAO Chenhui, WU Yini, WANG Jingjing

“…. -1.20%, P=0.044), along with a reduction in stride frequency cost (-0.85% vs. 0.14%, P=0.042).ConclusionsWhile dual-task conditions generally impair gait parameters in older adults, individuals with higher balance abilities maintain more stable gait patterns during motor dual-tasks, demonstrating greater resilience to interference. …”
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Effects of two warm-up protocols on isokinetic knee strength, jumping ability and sprint swimming performance in competitive swimmers by Zixiang Zhou, Pedro G. Morouço, Athanasios A. Dalamitros, Chao Chen, Weijia Cui, Rui Wu, Jian Wang

“…The conventional (Hcon: Qcon) and functional (Hecc: Qcon) ratios were calculated pre- and post- intervention. …”
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Extravascular supported arteriovenous fistulas reduced the need for interventions to support maturation and time to achieve two-needle cannulation for end-stage kidney disease pati... by Mohamad A. Hussain, MD, PhD, C. Keith Ozaki, MD, David Nation, MD, Jason Burgess, MD, Dirk M. Hentschel, MD, C.Steven Settle, MD, John F. Lucas, MD, Ellen Dillavou, MD, Alik Farber, MD, MBA

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Non-feature-specific elevated responses and feature-specific backward replay in human brain induced by visual sequence exposure by Tao He, Xizi Gong, Qian Wang, Xinyi Zhu, Yunzhe Liu, Fang Fang

“…Together, these findings demonstrate that visual sequence exposure induces twofold brain plasticity that may simultaneously serve for different functional purposes. The non-feature-specific elevated responses may facilitate general processing of upcoming stimuli, whereas the feature-specific backward replay may underpin passive learning of visual sequences.…”
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Improving older people’s experiences and safety at transitions of care: the PACT mixed-methods study including RCT by Jenni Murray, Ruth Baxter, Jane O’Hara, Laura Sheard, Catherine Hewitt, Natasha Hardicre, Charles Vincent, Eirini Oikonomou, Gerry Richardson, Rosie Shannon, Kalpita Baird, Stephen Brealey, Robbie Foy, Laura Mandefield, Sarah Hampton, Ed Breckin, Lubena Mirza, Alfredo Palacios, Sally Moore, Jayne Marran, Jacqui Elliot, Jane Schofield, Alison Cracknell, Beth Woods, Sarah Cockayne, Thomas Mills, Yvonne Birks, Olivia Joseph, Rebecca Lawton

“…Work package 4: Development and refinement of a transitions intervention Intervention development Guided by stakeholder workshops with patients and staff we co-designed a prototype intervention to support management of the four key functions (see above): knowing more, moving more, managing medicines and escalation. …”
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A splice donor variant in SLAMF1 is associated with canine atopic dermatitis by Oliver P. Forman, Jamie Freyer, Abigail Kerr, Julia D. Labadie, Michael Denyer, Debbie J. Gow, Janet Alexander, Michelle Daya, Yaindrys Rodriguez Olivera, Cecilia Lozoya, Christian Leutenegger, Christian Savard, Jason T. Huff, Rebecca Chodroff Foran

“…Whole-genome resequencing revealed a compelling splice donor variant in the signaling lymphocytic activation molecule 1 (SLAMF1), a transmembrane receptor with important functions in immune cells. Further analysis of additional genome sequences and RNA samples from the MARS PETCARE BIOBANK confirmed that the SLAMF1 splice variant is a strong potential contributor to an increased risk of atopic dermatitis.DiscussionThe discovery represents the first compelling genetic variant associated with CAD to be validated in more than one breed of dog. …”
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Proteomic profiling improves prognostic risk stratification of the Sarculator nomogram in soft tissue sarcomas of the extremities and trunk wall by Madhumeeta Chadha, Sara Iadecola, Andrew Jenks, Valeriya Pankova, Yuen Bun Tam, Jessica Burns, Amani Arthur, Christopher P. Wilding, Liang Chen, Priya Chudasama, Dario Callegaro, Dirk C. Strauss, Khin Thway, Alessandro Gronchi, Robin L. Jones, Rosalba Miceli, Sandro Pasquali, Paul H. Huang

“…Abstract Background High‐risk soft tissue sarcomas of the extremities and trunk wall (eSTS), as defined by the Sarculator nomogram, are more likely to benefit from (neo)adjuvant anthracycline‐based therapy compared to low/intermediate‐risk patients. …”
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Construction of mitochondrial signature (MS) for the prognosis of ovarian cancer by Miao Ao, You Wu, Kunyu Wang, Haixia Luo, Wei Mao, Anqi Zhao, Xiaomeng Su, Yan Song, Bin Li

“…GO and KEGG analysis confirmed these genes were enriched in the generation of precursor metabolites and energy. It illustrated more lymphocyte infiltration in the high MS group than low MS group. …”
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Repurposed clindamycin suppresses pyroptosis in tumor-associated macrophages through Inhibition of caspase-1 by Adrian Weich, Johannes Berges, Cindy Flamann, Katrin Bitterer, Krishna Pal Singh, David Chambers, Christopher Lischer, Xin Lai, Olaf Wolkenhauer, Carola Berking, Gerhard Krönke, Shailendra Gupta, Heiko Bruns, Julio Vera, Research Group Macrophages

“…The method generates a ranking of drug-target interactions, the most promising of which are channeled towards experimental validation. …”
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Identification and validation of an explainable machine learning model for vascular depression diagnosis in the older adults: a multicenter cohort study by Ran Zhang, Tian Li, Fan Fan, Haoying He, Liuyi Lan, Dong Sun, Zhipeng Xu, Sisi Peng, Jing Cao, Juan Xu, Xiaoxiang Peng, Ming Lei, Hao Song, Junjian Zhang

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Comparison of treatment outcomes in severe personality disorder patients with or without substance use disorders: a 36-month prospective pragmatic follow-up study by Lana F, Sanchez-Gil C, Adroher N, Perez Sola V, Feixas G, Martí-Bonany J, Torrens Melich M

“…These 28 cases were then compared to the 23 patients without SUD (PD-nSUD) in terms of psychiatric hospitalizations and psychiatric emergency room (ER) visits before and during the 6-month therapeutic intervention and every 6 months thereafter for a total of 36 months.Results: The baseline clinical characteristics correspond to a sample of PD patients (78% met DSM-IV criteria for borderline PD) with poor general functioning and a high prevalence of suicide attempts and self-harm behaviors. …”
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Health promotion and cardiovascular risk reduction in people with spinal cord injury: physical activity, healthy diet and maintenance after discharge— protocol for a prospective na... by Nicolaj Jersild Holm, Tom Møller, Lis Adamsen, Line Trine Dalsgaard, Fin Biering-Sorensen, Lone Helle Schou

“…Introduction Spinal cord injury (SCI) predisposes those who suffer from it to physical inactivity and weight gain; consequently, death due to cardiovascular diseases is more frequent among people with SCI than in the general population. …”
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Clinical, nutritional, anthropometric indicators and frequency of occurrence of Ala16Val (rs4880) polymorphic locus of the <i>MnSOD</i> gene in vibration disease comorbid with arte... by A. M. Gorbunova, O. N. Gerasimenko, I. S. Shpagin, M. S. Medvedkina, V. N. Maksimov, Yu. A. Nikolaev

“…A complex of clinical, anthropometric, laboratory, functional and genetic studies has been carried out. …”
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Neuroprotective properties of n-phenylacetyl-l-prolylglycine ethyl ester nasal gel in an experimental model of multiple sclerosis equivalent by B.S. Burlaka, I.F. Belenichev, O.O. Nefedov, O.G. Aliyeva, N.V. Bukhtiyarova

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Uso de retalhos microcirúrgicos em pacientes queimados: revisão da literatura Use of microsurgical flaps for the treatment of burn patients: a literature review by Bruno Barros de Azevedo Coutinho, Marina Buainain Balbuena, Tatyanne Ferreira da Silva, Fábio Tacla Saad, Kleder Gomes de Almeida, Paulete Yuri Nukariya Gomes de Almeida

“…For more than 3 decades, microsurgery has been used to repair significant tissue losses in a single surgical procedure. …”
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BLACK HUMOUR: ORIGIN DESCRIPTION AND AN ATTEMPT OF IDENTIFICATION by Iryna A. Blynova.

“…The compositional and speech means of organising black humour is based on opposition, antonymy of lexical units, contrast. The functioning of hyperbole, verbal and situational irony, and paradox are frequent at the lexical and semantic level. …”
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Gut Microbiome and Metabolite Characteristics Associated With Different Clinical Stages in Non-Small Cell Lung Cancer Patients by Liu F, Lu X, Tang M, Chen Y, Zheng X

“…Notably, Lachnospira and Blautia were more abundant in healthy controls. The distribution of gut microbial species in patients with varying stages of NSCLC was uneven, with Bacteroides and Bacteroidaceae being most prevalent in stage T2, and Prevotella dominating in stage T4. …”
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