Effectiveness of Digital Health Interventions for Chronic Obstructive Pulmonary Disease: Systematic Review and Meta-Analysis by Miaoqing Zhuang, Intan Idiana Hassan, Wan Muhamad Amir W Ahmad, Azidah Abdul Kadir, Xiaodong Liu, Furong Li, Yinuo Gao, Yang Guan, Shuting Song

“…ObjectiveThis systematic review and meta-analysis assesses the clinical effectiveness of smartphone apps, wearable monitors, and web-delivered platforms in four COPD management areas: (1) quality of life (measured by the COPD Assessment Test [CAT] and St George’s Respiratory Questionnaire), (2) self-efficacy (assessed by the General Self-Efficacy Scale), (3) functional capacity (evaluated via the 6-minute walk test and Modified Medical Research Council Dyspnea Scale), and (4) health care use (indicated by hospital and emergency department visits). …”
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Epigenome profiling reveals distinctive regulatory features and cis-regulatory elements in pepper by Hongji Yang, Guorong Yu, Zhidong Lv, Tonghui Li, Xi Wang, Ying Fu, Zhangsheng Zhu, Guangjun Guo, Hang He, Ming Wang, Guochen Qin, Feng Liu, Zhenhui Zhong, Yan Xue

“…While the large and complex genome of pepper severely hampered the understanding of its functional genome, it also indicates a rich yet unexplored reservoir of regulatory elements (REs). …”
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Socio-economic model of the new system of higher environmental education in Russia by Alla V. Guslyakova, Alla V. Guslyakova, Konstantin V. Isaev, Tatyana N. Ledashcheva, Nailya G. Valeeva, Nina I. Guslyakova

“…Therefore, it is highly recommended focusing on the further research and analysis of the potential risks that can limit the efficacy of the system functioning and evolution in the future.…”
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Exploring the Possibility of Medical Device Surveillance in Patients on Peritoneal Dialysis Using a Common Data Model by Seon Min Kim, Sooin Choi, You Kyoung Lee, Cheol Wan Lim, Byung Chul Yu, Moo Yong Park, Jin Kuk Kim, Seng Chan You, Seo Jeong Shin, Soo Jeong Choi

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Case Report: The intersection of psychiatry and medicine: diagnostic and ethical insights from case studies by Francesco Monaco, Francesco Monaco, Annarita Vignapiano, Annarita Vignapiano, Martina D’Angelo, Fabiola Raffone, Valeria Di Stefano, Antonella Boccia, Anna Longobardi, Benedetta Di Gruttola, Michele Fornaro, Giulio Corrivetti, Giulio Corrivetti, Iolanda Martino, Luca Steardo, Luca Steardo, Luca Steardo

“…The article critically examines terms like medically unexplained symptoms and functional disorders, highlighting their limitations and potential for misuse. …”
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Cell-Free DNA (cfDNA) Regulates Metabolic Remodeling in the ES-2 Ovarian Carcinoma Cell Line, Influencing Cell Proliferation, Quiescence, and Chemoresistance in a Cell-of-Origin-Sp... by Isabel Lemos, Catarina Freitas-Dias, Ana Hipólito, José Ramalho, Fabrizio Carteni, Luís G. Gonçalves, Stefano Mazzoleni, Jacinta Serpa

“…We observed instant reactions of adopting the metabolic profile that brings back the cell functioning of more favorable culture conditions supporting proliferation and resembling the cell of origin of the cfDNA variant, as observed in unselected ES-2 cells. …”
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Prevalence of Extended-Spectrum β-Lactamase-Producing <i>Escherichia coli</i>, <i>Klebsiella pneumoniae</i> and <i>Enterobacter cloacae</i> in Wastewater Effluent in Blantyre, Mala... by Edna Ibrahim, Charity Mkwanda, Edward Masoambeta, Luigia Scudeller, Tomislav Kostyanev, Hussein H. Twabi, Yohane K. Diness, Jobiba Chinkhumba, Janelisa Musaya, Rajhab S. Mkakosya, Surbhi Malhotra-Kumar, Chantal M. Morel, Save Kumwenda, Chisomo L. Msefula

“…<b>Results</b>: A total of 288 samples were collected between April 2023 and March 2024, and 97.6% (281/288) yielded one or more presumptive ESBL isolates. Bacterial growth was confirmed as 48.9% <i>Ec</i> (255/522), 33.0% <i>Kp</i> (172/522), and 10.0% <i>Enc</i> (52/522). …”
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Development and validation of a disulfidptosis-related genes signature for predicting outcomes and immunotherapy in acute myeloid leukemia by Han Gong, Han Gong, Ying Zhang, Xusheng Wu, Yiming Pan, Yiming Pan, Mingwei Wang, Mingwei Wang, Xiaofeng He, Jing Liu, Zhong Liu, Zhong Liu, Ling Li

“…Moreover, experiments validated the functions of PTPN6 and CSK in OCI-AML2 cells.ResultsWe identified 10 prognostic DRGs and revealed two disulfidptosis subtypes. …”
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New genomic resources inform transcriptomic responses to heavy metal toxins in the common Eastern bumble bee Bombus impatiens by Amy L. Toth, Christopher D. R. Wyatt, Rick E. Masonbrink, Katherine S. Geist, Ryan Fortune, Sarah B. Scott, Emeline Favreau, Sandra M. Rehan, Seirian Sumner, Mary M. Gardiner, Frances S. Sivakoff

“…In the brain, differentially expressed genes had biological functions related to chaperone activity and protein folding. …”
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Integrating Tumor Hypoxic Sensing and Photothermal Therapy Using a Miniaturized Fiber‐Optic Theranostic Probe by Fangzhou Jin, Zhiyuan Xu, Wei Wang, Zhongyuan Cheng, Yang Wu, Zesen Li, Enlai Song, Xu Yue, Yong Kang Zhang, Wei Li, Youzhen Feng, Donglin Cao, Dongmei Zhang, Minfeng Chen, Xiangran Cai, Yang Ran, Bai‐Ou Guan

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Label-Free Optical Transmission Tomography for Direct Mycological Examination and Monitoring of Intracellular Dynamics by Eliott Teston, Marc Sautour, Léa Boulnois, Nicolas Augey, Abdellah Dighab, Christophe Guillet, Dea Garcia-Hermoso, Fanny Lanternier, Marie-Elisabeth Bougnoux, Frédéric Dalle, Louise Basmaciyan, Mathieu Blot, Pierre-Emmanuel Charles, Jean-Pierre Quenot, Bianca Podac, Catherine Neuwirth, Claude Boccara, Martine Boccara, Olivier Thouvenin, Thomas Maldiney

“…Live-cell imaging generally requires pretreatment with fluorophores to either monitor cellular functions or the dynamics of intracellular processes and structures. …”
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Single-cell sequencing uncovers a high ESM1-expression endothelial cell subpopulation associated with bladder cancer progression and the immunosuppressive microenvironment by Yifeng Qiu, Yuhan Wang, Jiahe Liu, Baohua Liu, Kai Sun, Qi Hou

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Construction of a novel radioresistance-related signature for prediction of prognosis, immune microenvironment and anti-tumour drug sensitivity in non-small cell lung cancer by Yanliang Chen, Chan Zhou, Xiaoqiao Zhang, Min Chen, Meifang Wang, Lisha Zhang, Yanhui Chen, Litao Huang, Junjun Sun, Dandan Wang, Yong Chen

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Peran Hukum dalam Pengelolaan dan Perlindungan Lahan Gambut by Eko Nuriyatman, Arrie Budhiartie, Latifah Amir

“…The novelty of this study lies in its specific focus on examining the implementation of legal regulations in peatland management in Tanjung Jabung Timur Regency, differing from previous studies that have been more general at the national level. The research findings indicate that the main obstacles in the implementation of peatland management laws include weak law enforcement, regulatory overlaps, conflicts of interest, and low public legal awareness. …”
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MODERN CONCEPTS OF TREATING HYPERESTHESIS OF HARD TOOTH TISSUES (REVIEW OF LITERATURE) by S.P. Yarova, O.S. Genzytska, Yu.Yu. Yarov, A.A. Komlev

“…Starting from an earlier age women suffer more often than men. The generalized form of hyperesthesia is usually associated with such general causes as the functional state of the nervous system, endocrine diseases, disorders of mineral metabolism in the body. …”
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Glial and immune dysregulation in glaucoma independent of retinal ganglion cell loss: a human post-mortem histopathology study by Akanksha Salkar, Viswanthram Palanivel, Devaraj Basavarajappa, Mehdi Mirzaei, Angela Schulz, Peng Yan, Vivek Gupta, Stuart Graham, Yuyi You

“…This gliotic response differed across conditions, with astrocyte activation being more prominent in DM and microglial activation predominating in AMD. …”
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Safety of 3 Tesla Magnetic Resonance Imaging in Patients with Sickle Cell Disease by Olivia Justice, Lori C. Jordan, Chelsea A. Lee, Niral J. Patel, Spencer Waddle, Sumit Pruthi, L. Taylor Davis, Adetola A. Kassim, Manus J. Donahue

“…Sickle cell disease (SCD) is a well-characterized hemoglobinopathy affecting more than 20 million individuals worldwide and carries an increased risk of cerebral vasculopathy, cerebral infarct, and stroke. …”
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Borderline personality disorder Athens study: a quasi-experimental pragmatic trial for the assessment of a public, psychodynamic, stepped care service for borderline personality di... by Ioannis Malogiannis, Lida Anagnostaki, Maria Aspradaki, Panagiotis Aristotelidis, Katerina Karambela, Maria Amperiadou, Vasiliki Efthymiou, Phaithra Kriezi, Ioanna Theodoridou, Pentagiotissa Stefanatou, Pentagiotissa Stefanatou, George Konstantakopoulos, George Konstantakopoulos, Kyriakos Souliotis, Lily E. Peppou, Eleni Giannoulis, Eleni Giannoulis

“…The secondary outcome measures will include measures of general psychopathology, psychosocial functioning, quality of life and retention in treatment. …”
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BASE: a web service for providing compound-protein binding affinity prediction datasets with reduced similarity bias by Hyojin Son, Sechan Lee, Jaeuk Kim, Haangik Park, Myeong-Ha Hwang, Gwan-Su Yi

“…These resources contribute to the development of generalized and robust predictive models, enhancing the accuracy and reliability of DTA predictions in the drug discovery process. …”
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Peculiarities of endoscopic treatment of vesicoureteral reflux in children by V.V. Pohoriliy, V.S. Konoplitskyi, T.I. Mykhalchuk, Yu.A. Dymchyna, Yu.Ye. Korobko

“…Regarding the gender distribution of the pathology, it should be noted that girls are sick more often than boys. Unilateral and bilateral VUR occurs with the same frequency, while reflux of the II–III stages occurs most often. …”
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