Towards an Interoperable Digital Scholarly Edition by Desmond Schmidt

“…This would facilitate not only the development of more general software for handling DSEs, but also enable existing programs that already handle these kinds of data to function more efficiently.…”
Get full text

SMA Community Priorities for Future Drug Therapies: Cross-Sectional Survey Findings Representing 410 Adults with SMA by Ilse S. Peterson, Ramaa Chitale, Mary A. Curry, Lisa T. Belter

“…Most notably, people with more severe types of SMA and lower mobility were more likely to report items related to lung function and bulbar function as important. …”
Get full text

Hyperspectral RGB Imaging Combined With Deep Learning for Maize Seed Variety Identification by Jian Li, Fan Xu, Shaozhong Song, Qi Ji, Junling Liu

“…After that, we improved the classic ResNet50 model by adding the coordinate attention (CA) mechanism to the end of each residual block and replacing the global ReLU activation function with SiLU. This improvement enabled the model to capture more precise and detailed features while enhancing its predictive capability. …”
Get full text

Prediction of mutational tolerance in HIV-1 protease and reverse transcriptase using flexible backbone protein design. by Elisabeth Humphris-Narayanan, Eyal Akiva, Rocco Varela, Shane Ó Conchúir, Tanja Kortemme

“…We find the model correctly captures a considerable fraction of protease and reverse-transcriptase mutational tolerance and shows comparable accuracy using either experimentally determined or computationally generated structural ensembles. Predictions of tolerated sequence space afforded by the model provide insights into stability-function tradeoffs in the emergence of resistance mutations and into strengths and limitations of the computational model.…”
Get full text

CAPTCHA Recognition Method Based on CNN with Focal Loss by Zhong Wang, Peibei Shi

“…For this reason, the paper proposes a CAPTCHA recognition method based on convolutional neural network with focal loss function. This method improves the traditional VGG network structure and introduces the focal loss function to generate a new CAPTCHA recognition model. …”
Get full text

Study on the Macroeconomic Model Based on the Genetic Algorithm by Sun Shihao, Yixin Zhou, Yong Wang, Wu Wang

“…In order to design a more reliable general push time cycle prediction software for macroeconomic indicators, a set of general software is used to serve financial transactions, bulk material transactions, international trade, macro-control and other fields, so as to improve the prediction of macroeconomic indicators. …”
Get full text

What patients with lung cancer with comorbidity tell us about interprofessional collaborative care across healthcare sectors: qualitative interview study by Michel Wensing, Johanna Forstner, Michael Thomas, Jasmin Bossert, Matthias Villalobos, Anja Siegle, Corinna Jung, Nicole Deis, Katja Krug

“…Healthcare providers should be more aware of care recipients’ willingness of taking on a more active role in healthcare coordination.Trial registration number DRKS00013469.…”
Get full text

Modified Heisenberg Commutation Relations, Free Schrödinger Equations, Tunnel Effect and Its Connections with the Black–Scholes Equation by Mauricio Contreras González, Roberto Ortiz Herrera, José González Suárez

“…For the position deformation case, the corresponding free wave functions are sinusoidal functions with a variable wave vector <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>k</mi><mo stretchy="false">(</mo><mi>x</mi><mo stretchy="false">)</mo></mrow></semantics></math></inline-formula>. …”
Get full text

Human diseases caused by homozygous PTH1R mutations by Ignacio Portales-Castillo, Jakob Höppner, Harald Jüppner, Harald Jüppner, Thomas J. Gardella

Get full text

Geometric entropies and their Hamiltonian flows by Xi Dong, Donald Marolf, Pratik Rath

“…When higher derivative corrections are included, the role of the area is instead played by a more general functional known as the geometric entropy. …”
Get full text

Optimal surgery sequence in the treatment of degenerative hip-spine syndrome: a propensity score-based inverse probability of treatment weighting analysis by Yiming Fan, Yi Huang, Tianhao Wang, Qi Wang, Han yu, Chao Xue, Guoquan Zheng, Yan Wang

“…When comparing between the two groups, the surgical sequence exhibits equivalent effects on functional improvement and complication rates. The radiological outcomes indicate that the THA→LF group shows more pronounced effects on PT and SS, suggesting a more favorable impact on pelvic alignment in patients undergoing this sequence. …”
Get full text

Outcomes of Surgical Fixation of Lisfranc Injuries: A 2-year Review by Gideon JW Cheok, Akshay Padki, Kinjal V Mehta

Get full text

Systemic reviews and meta-analysis of the use of midodrine in hepatorenal syndrome by Prem Balaji Reddy Lankapothu, Shrinidhi B., Satish Kumar M., Magesh Kumar S.

Get full text

Proteasome caspase-like activity regulates stress granules and proteasome condensates by Shirel Steinberger, Julia Adler, Nadav Myers, Yosef Shaul

“…To investigate the functional implications of CL activity, we generated cell lines devoid of CL function by introducing the PSMB6 T35A mutation. …”
Get full text

From syndromic clues to diagnosis: understanding CARD11-driven disorders by Elena García-Martínez, Elena García-Martínez, María Teresa Schiaffino, María Teresa Schiaffino, Marisa Di Natale, Marisa Di Natale, María de las Mercedes Díaz Luna, Daniel Alejandro Viteri Álvarez, María Alejandra Mejía González, María Alejandra Mejía González

Get full text

Comparison of wavelet approximation order in different smoothness spaces by M. R. Islam, S. F. Ahemmed, S. M. A. Rahman

“…In this study we proved this assumption only for the Haar wavelet. Haar function is an example of wavelet and this fundamental example gives major feature of the general wavelet. …”
Get full text

3D Spheroid Culture Enhances the Expression of Antifibrotic Factors in Human Adipose-Derived MSCs and Improves Their Therapeutic Effects on Hepatic Fibrosis by Xuan Zhang, Ming-Gen Hu, Ke Pan, Chong-Hui Li, Rong Liu

Get full text

Modal Shift in Public Transport Under Fiscal-Based Policies Scenarios for Jakarta by Alfa Adib Ash Shiddiqi, Dwita Sutjiningsih, Tri Tjahjono, Linda Darmajanti, Gede B. Suprayoga

“…A stated preference survey was conducted, and a binomial logit model and standard utility function were developed for analysis. Diagrams showing commuters' willingness to shift to public transport were then generated from the analysis. …”
Get full text

A Nonlinear Deep Learning Model for Oxygen Content of Flue Gas by TANG Zhenhao, LI Yanyan, CAO Shengxian

“…In order tostudy the reliability of the ZZ distribution under the condition of no failure data, and the reliability function is transformed, and the concavity and convexity is used to obtain a more precise relationship between the reliability of the products at each detection timeFurther, under the prior distribution is the uniform distribution or more general distribution, Bayesian Estimation of the reliability at each moment is given Meanwhile, according to the optimal confidence lower limit formula of known function with confidence level of 1－α in the case of no failure data, the optimal confidence lower limit expression of the reliability function is given, and the simplified form that is convenient to use is obtained in several special cases.…”
Get full text

The Effectiveness of Computerized Cognitive Training in Patients With Poststroke Cognitive Impairment: Systematic Review and Meta-Analysis by Min Gao, Lu Huang, Jiang Yi, Tianqi Zhang, Guangyao Zhu, Qi Zhang, Jiaxiao Tian, Rongxuan Zhao, Xiaoqin Duan, Zhongliang Liu

“…ConclusionsBased on moderate to severe levels of evidence, we conclude that CCT can significantly enhance general cognitive function, attention, executive function, and quality of life in PSCI patients. …”
Get full text