Increased nuclear factor I-mediated chromatin access drives transition to androgen receptor splice variant dependence in prostate cancer by Larysa Poluben, Mannan Nouri, Jiaqian Liang, Shaoyong Chen, Andreas Varkaris, Betul Ersoy-Fazlioglu, Olga Voznesensky, Irene I. Lee, Xintao Qiu, Laura Cato, Ji-Heui Seo, Matthew L. Freedman, Adam G. Sowalsky, Nathan A. Lack, Eva Corey, Peter S. Nelson, Myles Brown, Henry W. Long, Joshua W. Russo, Steven P. Balk

“…AR and nuclear factor I (NFI) motifs are most enriched at more accessible sites, and NFIB/X knockdown greatly diminishes ARv7 function. …”
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BRAF inhibitor resistance of melanoma cells triggers increased susceptibility to natural killer cell-mediated lysis by Antoine Toubert, Eric Pasmant, Alexandra Frazao, Louise Rethacker, Géraldine Jeudy, Marina Colombo, Marie-Françoise Avril, Helene Moins-Teisserenc, Marie Roelens, Sophie Dalac, Eve Maubec, Anne Caignard

“…Soluble NKG2D ligands known to regulate the receptor function have been associated to cancer progression. …”
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Comprehensive Evaluation of Operation Safety of Earth-rock Dams Based on Weight Optimization-cloud Model by ZHANG Jianwei, WU Weitao, HOU Ge, HUANG Jinlin, WANG Bingpeng, LIU Hongze, HU Zixu

“…The membership degree was calculated by generating different numbers of cloud droplets through the forward cloud generators, which were taken as the model solution under each number of cloud droplets. …”
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Effector T cells under hypoxia have an altered transcriptome similar to tumor-stressed T cells found in non-responsive melanoma patients by Ahmad A Tarhini, Zhihua Chen, Dongliang Du, Joshua Davis, Justin C Boucher, Katarzyna A Rejniak, Jose A Guevara-Patino, Timothy I Shaw, Alyssa Obermayer, Mate Z Nagy, Lourdes B Plaza-Rojas, Elena Kostenko, Anna L Austin, Awino Maureiq E Ojwang'

“…We created tumor maps and derived plots showing the fraction of CD4 and CD8 T cells against the distance to the nearest vessel and oxygen pressure. To assess their function and transcriptional changes caused by hypoxia, effector T cells were generated and cultured under hypoxia (0.5% oxygen) or normoxia (21% oxygen). …”
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DEVELOPMENT OF AN AUTOMATED FLUORESCENCE MICROSCOPY ASSAY FOR QUANTIFYING FACTORS AFFECTING RED BLOOD CELL (RBC) SICKLING IN SICKLE CELL DISEASE (SCD) by ML Arrojo, ACS Pinto, SK Haddad, RA Panepucci

“…However, the lack of straightforward functional assays to quantitate how these factor affect cell sickling, hamper a more profound understanding of SCD physiopathology. …”
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Atopic dermatitis by Stuart Carr, Rebecca Pratt, Fred White, Wade Watson

“…Systemic immunosuppressive agents may also be used, but are generally reserved for severe flare-ups or more difficult-to-control disease. …”
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Small Target Detection Algorithm for UAV Aerial Images Based on Improved YOLOv7-tiny by ZHANG Guanghua, LI Congfa, LI Gangying, LU Weidang

“…This study proposes a small target detection algorithm for UAV aerial images using a ConvMixer detection head based on the improved YOLOv7-tiny to address the problems of missed detection and false detection caused by significant variations in target scale, densely distributed small-sized targets and complex backgrounds in UAV aerial images.MethodsFirst, the activation function LeakyReLU is replaced with SiLU to compensate for the limited nonlinear expression of LeakyReLU and to enhance convergence speed and model generalization during training. …”
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Clinical Versatility of the Facility-Equator Implant System as Mandibular Overdenture Retainers by Anna Paula da Rosa Possebon, Alessandra Julie Schuster, Amália Machado Bielemann, Ana Paula Pinto Martins, Samille Biasi Miranda, Otacílio Luiz Chagas-Júnior, Luciana de Rezende Pinto, Fernanda Faot

“…The case with 4 implants and progressive loading showed a slight worsening of masticatory function at 1 year, in addition to a more pronounced MBL compared to other cases, but with improvements in satisfaction and oral health-related quality of life. …”
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CPT1C deficiency in SF1 neurons impairs early metabolic adaptation to dietary fats, leading to obesity by A. Fosch, D.S. Pizarro, S. Zagmutt, A.C. Reguera, G. Batallé, M. Rodríguez-García, J. García-Chica, O. Freire-Agulleiro, C. Miralpeix, P. Zizzari, D. Serra, L. Herrero, M. López, D. Cota, R. Rodríguez-Rodríguez, N. Casals

“…After long-term HFD exposure, SF1-Cpt1c-KO mice are more prone to developing obesity and glucose intolerance than control littermates, with males exhibiting a more severe phenotype. …”
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Human motion similarity evaluation based on deep metric learning by Yidan Zhang, Lei Nie

“…In addition, the dynamic time warping (DWT) algorithm is exploited to align the sequence of action information feature vectors temporally, which solves the problem of temporal axis discrepancies in realizing similarity metrics based on action information feature vectors. More accurate and reliable human action similarity evaluation results were achieved by the loss function composed of three components, namely, cross-reconstruction loss, reconstruction loss and triplet loss. …”
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The importance of compatibility of Customer Relationship Management, e-marketing, and e-commerce information systems to improve business efficiency by Dimitrijević Dragan, Dimitrijević Natalija, Adamović Živoslav

“…The paper analyzes and points to correlational relationships, as well as elements of necessary coherence and cause-and-effect complementarity and compatibility of CRM information systems with information systems of e-marketing, e-commerce, and techniques and tools of ICT support for users, with the aim of more efficient business and generation sustainable competitiveness.…”
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Mirror Visual Feedback to Improve Bradykinesia in Parkinson’s Disease by Gaia Bonassi, Elisa Pelosin, Carla Ogliastro, Cecilia Cerulli, Giovanni Abbruzzese, Laura Avanzino

“…MVF therapy could tentatively treat bradykinesia since the untrained hand, which benefits from the exercise, is generally more severely impaired in undertaking sequential movements. …”
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Heterogeneous foraging swarms can be better by Gal A. Kaminka, Yinon Douchan

“…We show that AEI provably generalizes previous work, adding a component that computes the effect of counterfactual robot absence. …”
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Central venous stenosis and methods of its treatment in hemodialysis patients by Z. B. Kardanakhishvili, A. B. Zulkarnaev

“…Against the background of functioning AVF from the ipsilateral side, CVS proceeds with much more pronounced symptoms than in the general population of patients with this pathology. …”
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COMPARATIVE EVALUATION OF OSTEOTROPIC ACTION OF ENDODONTIC FILLING MATERIALS ON THE MODEL OF EXPERIMENTAL DESTRUCTION OF BONE TISSUE OF THE JAW OF RATS by I. Han

“…Osteotropic compositions based on beta tricalcium phosphate and calcium hydroxyapatite stimulate more processes of osteogenesis than drugs MTA and Nano Gen, affecting on mineralized function that shows the increasing of te content of ALP, reducing the concentration of CF and, in addition, increasing their indicator of mineralization. …”
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Establishing a 3D Spheroid Model of Cholinergic Neurons from SH-SY5Y Cells for Neurotoxicity Assessment by Felipe Franco-Campos, Mónica Fernández-Franzón, Yelko Rodríguez-Carrasco, María-José Ruiz

“…SH-SY5Y cells, an immortalized human neuroblastoma cell line, provide a more accessible alternative for studying neuronal processes and neurotoxicity. …”
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A DEM super resolution reconstruction method based on normalizing flow by Jie Yu, Yangtenglong Li, Xuan Bai, Ronghao Yang, Mengxue Cui, Haohao Wu, Zheng Li, Fangzheng Su, Ze Li, Taohuai Liang, Hongliang Yan

“…The negative log-likelihood function and pixel loss function are used to accelerate the optimization to generate high-resolution DEM images that are closer to the natural terrain. …”
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Contrasting responses of soil bacterial and fungal networks to photovoltaic power station by Teng Li, Leilei Lu, Ziqing Kang, Huijun Li, Jihua Wu, Weiguo Du

“…These findings provide new evidence that soil bacterial networks are more sensitive to PV panels installation than fungal networks, deepening our understanding of land-use change effects on soil ecosystem functions. …”
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Introducing the dataset for measuring centrality for sustainability—A case study of Pecinci municipality, SerbiaMendeley DataMendeley Data by Tatjana Mrđenović

“…This innovative approach considers a broader range of factors, such as economic vitality and social equity, to create a more comprehensive and holistic plan for central activities. …”
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Virtual and Augmented Reality for Chronic Musculoskeletal Rehabilitation: A Systematic Review and Exploratory Meta-Analysis by Theodora Plavoukou, Pantelis Staktopoulos, Georgios Papagiannis, Dimitrios Stasinopoulos, George Georgoudis

“…<b>Objective:</b> To systematically evaluate the effectiveness of VR, AR, and exergaming interventions in improving pain, function, balance, and psychological outcomes among adults with CMDs. …”
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