Leber hereditary optic neuropathy: utilities and carer burden from British and Irish participants by Claire Lawrence, Emma Williams, Andrew Mumford, Steve Bojakowski, Julio Benedicto, Andrew Lloyd

“…The condition affects numerous aspects of daily life, functioning and overall health-related quality of life (HRQL), which may spillover to carers. …”
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Selective beta-blocker bisoprolol: effectiveness and safety in complex treatment of patients with chronic heart failure and Type 2 diabetes mellitus. RAMBO-DM CHF Study results by Yu. V. Lapina, A. A. Petrukhina, O. Yu. Narusov, V. Yu. Mareev, M. G. Bolotina, M. V. Shestakova, V. P. Masenko, G. N. Litonova, N. A. Baklanova, Yu. N. Belenkov

“…The examination included clinico-functional assessment of general status, renal function, neuro-hormonal profile, circadian heart rate variability, and carbohydrate metabolism (glycated hemoglobin level, standard breakfast test with fasting and 2- hour postprandial measurements of plasma glucose, insulin and C-peptide levels).Results. …”
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Wearable sensors for measuring spontaneous upper limb use in children with unilateral cerebral palsy and typical development by Elena Beani, Mattia Franchi de ’Cavalieri, Silvia Filogna, Veronica Barzacchi, Matteo Cianchetti, Martina Maselli, Giada Martini, Valentina Menici, Giuseppe Prencipe, Elisa Sicola, Giovanni Cioni, Giuseppina Sgandurra

“…Abstract Background Unilateral Cerebral Palsy (UCP) is a clinical condition which mainly involves the movement and muscle tone of one side of the body, often impacting the general manual function. While there are some clinical assessment tools aimed to quantify the Upper Limbs (UpLs) use and the manual abilities, acquiring information regarding the motor abilities outside the clinical environment, such as the UpLs use and their asymmetry during daily life, could provide a more complete evaluation of the child and open a new clinical reasoning. …”
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Exploring the Time to Onset and Early Predictors of Poststroke Spasticity Combined With Surface Electromyography: Protocol for a Nested Case-Control Study by Simeng Song, Shiliang Wang, Shanshan Zeng, Wenqing Wu, Lingying Wu, Xukun Tang, Xiongxing Sun, Dahua Wu, Le Xie

“…This form of paralysis is more prevalent compared to other poststroke sequelae and is among the most challenging and complex symptoms to manage. …”
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SPECC1 as a pan-cancer biomarker: unraveling its role in drug sensitivity and resistance mechanisms by Dongwei Liu, Xidi Wang, Lingfei Cui, Mingxia Zhang, Kefeng Lei, Nijiati Aierken

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RAISE study protocol: a cross-sectional, multilevel, neurobiological study of resilience after individual stress exposure by Konstantinos Ioannidis, Paul Wilkinson, Paul Fletcher, Samantha N Sallie, Laura Moreno-López, Muzaffer Kaser, Katja Schueler, Adrian Dahl Askelund, Lorinda Turner, Anne-Laura van Harmelen, Alicia J Smith, Camilla Nord, Eugenia M Davidson, Nadia González-García, Oksana Berhe, Rosalie Shrofer, Sofia Orellana, Sophie L Bellow, Suzanne Schweizer

“…We hypothesise that resilient functioning will be facilitated by reduced morning cortisol and cytokine levels before and after the stressor and improved neural responses to such stress, as well as increased gray matter volume in the hippocampus and prefrontal cortex, enhanced inhibitory control and emotion regulation, and more friendship and family support.Ethics and dissemination This study has been reviewed and given favourable opinion by the National Research Ethics Service, NRES Committee East of England-Cambridge Central and external reviewers from the Royal Society (RGF\R1\180064 and RGF\EA\180029). …”
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Psychopersonal characteristics of women with varying degrees of menopausal disorders by N. S. Lutsenko, O. D. Mazur, O. S. Shapoval, L. I. Zvarich, N. F. Efimenko

“…Eisenko's test questionnaire, the Women's Sexual Function Index (FSFI) questionnaire, used the SF-36 (Medical Outcomes Study Short Form) general questionnaire to assess quality of life. …”
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Association of patent ductus arteriosus treatment in extremely low gestational age neonates with two year kidney outcomes: a secondary analysis of the preterm erythropoietin neurop... by Paige E. Condit, Ronnie Guillet, Dinushan Kaluarachchi, Russell L. Griffin, Shina Menon, David J. Askenazi, Matthew W. Harer

“…Among those medically treated, indomethacin was used more commonly than either ibuprofen or acetaminophen. …”
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Unveiling microbial dynamics: a review of health and immune enhancement in school settings by Philip Asumang, Richard Ntumi, Francis Dwomoh

“…Understanding the role of microbes in school environments has implications for public health policies and educational practices, aiming to create healthier and more conducive learning environments for the younger generation. …”
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On the “Tantawy technique” and other methods for analyzing fractional Fokker–Plank type equations by Aljawhara H Almuqrin, CGL Tiofack, DV Douanla, A Mohamadou, Weaam Alhejaili, Sherif ME Ismaeel, Samir A El-Tantawy

“…Moreover, the novel “ Tantawy technique, ” developed for the first time, is highly accurate and efficient in analyzing the most complicated and nonlinear problems. It is also far more precise than the optimal auxiliary function method. …”
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Colorectal cancer-infiltrating NK cell landscape analysis unravels tissue-resident PD-1+ NK cells in microsatellite instability tumors by Valentina Obino, Chiara Giordano, Simona Carlomagno, Chiara Setti, Marco Greppi, Matteo Bozzo, Silvia Pesce, Silvia Pesce, Elisa Ferretti, Elisa Ferretti, Simona Candiani, Simona Candiani, Letizia Muccio, Enrico Ciferri, Tania Buttiron Webber, Agnese Solari, Fulvia Ortolani, Laura Paleari, Matteo Clavarezza, Andrea Barberis, Marco Filauro, Nicoletta Provinciali, Nicoletta Provinciali, Mariangela Rutigliani, Emanuela Marcenaro, Emanuela Marcenaro, Andrea DeCensi, Andrea DeCensi, Mariella Della Chiesa, Mariella Della Chiesa, Simona Sivori, Simona Sivori

“…Since CRC microenvironment can induce NK cell dysfunction and hinder cancer control, understanding tumor-associated NK cell features is mandatory to fully unlock their immunotherapeutic potential.PurposeOur study aims at elucidating the molecular and functional characteristics of tumor-associated NK cells in CRC focusing on the expression of immune checkpoints that critically regulate NK cell function. …”
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Changes in Upper Airway Airflow After Rapid Maxillary Expansion Beyond the Peak Period of Adenoidal Growth—A CBCT Study Using Computer Fluid Dynamics and Considering Adenoidal Dime... by Giuseppe Palazzo, Rosalia Leonardi, Gaetano Isola, Manuel Lagravere, Antonino Lo Giudice

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A Novel Detection-and-Replacement-Based Order-Operator for Differential Evolution in Solving Complex Bound Constrained Optimization Problems by Sichen Tao, Sicheng Liu, Shoya Ohta, Ruihan Zhao, Zheng Tang, Yifei Yang

“…This paper systematically reviews the functional differences between mechanism improvements and operator improvements in terms of exploration and exploitation capabilities, based on the general patterns of algorithm enhancements. …”
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Evaluation and driving force analysis of relative effectiveness in the giant panda national park in Sichuan, China by Bao Meng, Bao Meng, Mengchao Wang, Zhifeng Zhang, Hongyi Pan

“…The Qionglaishan and Adjacent Areas General Control Area (QLA-GCA) is dominated by the interaction of landscape pattern index with its remaining factors, and the rest of the functional areas are dominated by the interaction of natural factors such as temperature, evapotranspiration with its remaining factors. …”
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Telemonitoring for Chronic Heart Failure: Narrative Review of the 20-Year Journey From Concept to Standard Care in Germany by Sebastian Spethmann, Gerhard Hindricks, Kerstin Koehler, Stefan Stoerk, Christiane E Angermann, Michael Böhm, Birgit Assmus, Sebastian Winkler, Martin Möckel, Mirja Mittermaier, Monika Lelgemann, Daniel Reuter, Ralph Bosch, Alexander Albrecht, Stephan von Haehling, Thomas M Helms, Stefan Sack, Tarek Bekfani, Jan Wolfgang Gröschel, Magdalena Koehler, Christoph Melzer, Jan Wintrich, Bettina Zippel-Schultz, Georg Ertl, Claus Vogelmeier, Nikolaos Dagres, Jasmin Zernikow, Friedrich Koehler

“…Years of public funding in Germany have generated evidence that remote patient management improves outcomes for patients with CHF, such as quality of life, and reduces hospital admissions. …”
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Use of relative Patlak plot Ki′ images as an alternative to standard Patlak plot Ki images in clinical practice by Masatoyo Nakajo, Hirofumi Kawakami, Yutaro Kiyao, Mitsuho Hirahara, Akie Katsuki, Atushi Tani, Yukari Eizuru, Koji Takumi, Kiyohisa Kamimura, Fumiko Kanzaki, Takashi Yoshiura

“…Standard Patlak Ki imaging requires prolonged dynamic acquisition and full arterial input function (IF), limiting clinical feasibility. The relative Patlak plot omits the early-phase IF and focuses on the linear phase of tracer kinetics using only late dynamic data and a partially sampled IF. …”
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Embedding electronic patient-reported outcome measures into routine care for patients with stage III MELanoma (ePROMs-MEL): protocol for a prospective, longitudinal, mixed-methods... by Serigne Lo, Andrew Spillane, Donna Milne, Robyn Saw, Mbathio Dieng, Iris Bartula, Rachael Morton, Frances Boyle, Julia Lai-Kwon, Kathy Dempsey, Craig Lawn, Thomas Pennington, Skye Dong, Linda Seaman, Dina Saks, Jake Robert Thompson

“…Introduction The benefits of patient-reported feedback, using questionnaires that allow patients to report how they feel and function without any interpretation from healthcare professionals, are well established. …”
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Deviance from truth: Telemetry location errors erode both precision and accuracy of habitat‐selection models by Andrea T. Morehouse, Mark S. Boyce

“…GPS radiocollar data were more precise and more accurate, resulting in RSF models that were a better representation of true habitat selection by each wolf pack. © 2013 The Wildlife Society.…”
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Polishing inner wall of crossed deep micropores using magnetic microabrasive jet technology by Zezhi WANG, Jie WANG, Xiaogang MA, Fan LI, Xinya FAN, Yan CHEN

“…In view of the problems of conventional finishing processing of cross deep micro-holes being limited by size, uneven processing, and poor quality, and combined with the characteristics of a stable removal function and strong adaptability of the abrasive jet, the magnetic micro-abrasive jet technology finishing processing method is proposed to improve the quality of the inner wall of cross deep micro-holes.MethodsAn independent magnetic abrasive jet device was used to carry out finishing tests on the cross deep micro-holes, and an electromagnetic device was used to generate a focusing magnetic force near the nozzle outlet. …”
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The problem of related verbs in mental lexicon by Anastasia Chuprina

“…Based on the material of a group of Russian verbs and their prefi xed and suffi xed derivatives, this article studies which general information is more important for the lexical access to the primary word in the Russian language, i. e. the structural similarity of the verb with its prefi xed derivative or predictability of the change in semantics as to the suffi xed derivative. …”
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