The extracellular loop 2 (ECL2) of the human histamine H4 receptor substantially contributes to ligand binding and constitutive activity. by David Wifling, Günther Bernhardt, Stefan Dove, Armin Buschauer

“…To study the role of the FF motif in ECL2, we generated the hH4R-F168A mutant. The receptor was co-expressed in Sf9 insect cells with the G-protein subunits Gαi2 and Gβ1γ2, and the membranes were studied in [3H]histamine binding and functional [35S]GTPγS assays. …”
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Robust models of disease heterogeneity and control, with application to the SARS-CoV-2 epidemic. by Kory D Johnson, Annemarie Grass, Daniel Toneian, Mathias Beiglböck, Jitka Polechová

“…This not only reduces the median total infections and peak quarantine cases, but also controls outbreaks much more reliably: such a controller entirely prevents rare but large outbreaks. …”
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Phenotypic mutation rates and the abundance of abnormal proteins in yeast. by Martin Willensdorfer, Reinhard Bürger, Martin A Nowak

“…In our model, genes are regulated to synthesize a certain number of functional proteins. During this process, depending on the phenotypic mutation rate, abnormal proteins are generated. …”
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A Robust Adaptive Strategy for Diesel Particulate Filter Health Monitoring Using Soot Sensor Data by Bilal Youssef

“…The sensor data are projected to generate a 2D signature that reflects the changes in filtration efficiency. …”
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Vibroacoustic monitoring of bearing points failures in the driving system of the mining main ventilation fans by T. ZAKRZEWSKI

“…As there is no access to them in the course of operation, diagnostic methods which can be applied without dismantling the machine, and particularly vibroacoustic methods based on the fact that there is a dependence between failure-free operation and the vibroacoustic condition of bearings become more and more essential. The evaluation of the technical condition of rolling and slide bearings, based on measures of a vibratory signal, made on the basis of amplitude values of discrete components occurring in the spectra of the recorded vibratory signals, has; been the subject of diagnostic examinations. …”
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The issue of sustainable land use in Ukraine taking into account the consequences of the war by Liudmyla Datsenko, Svitlana Titova, Marharyta Dubnytska, Oksana Kustovska

“…Monographic analysis – used for the study and generalization of existing scientific approaches to the problem of land use; to determine the essence of the complex concept of “sustainable land management” and its economic, social, and ecological components, and to justify management components of the institutionalization of balanced land use, based on the realities of today’s Ukraine, taking into account the possibilities of more rapid development of the social-oriented market economy after the war. …”
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An enhanced CNN-Bi-transformer based framework for detection of neurological illnesses through neurocardiac data fusion by Kavita Rawat, Trapti Sharma

“…The proposed framework combines MEG, EEG, and ECG signals to create a more comprehensive understanding of brain and cardiac function in individuals with mental disorders. …”
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Accounting for tumor heterogeneity when using CRISPR-Cas9 for cancer progression and drug sensitivity studies. by Jessica F Olive, Yuanbo Qin, Molly J DeCristo, Tyler Laszewski, Frances Greathouse, Sandra S McAllister

“…We describe a novel CRISPR/Cas9 protocol that incorporates a single-cell cloning step prior to gene editing, allowing for the generation of appropriately matched, functionally equivalent control and edited cell lines. …”
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Exploring the impact of Brownian motion on novel closed-form solutions of the extended Kairat-II equation. by Khaled Aldwoah, Alaa Mustafa, Tariq Aljaaidi, Khidir Mohamed, Amer Alsulami, Mohammed Hassan

“…The first method is the modified Tanh technique linked with the Riccati equation, which is implemented to extract some closed-form solutions in the form of tangent and cotangent functions. The second technique is the Sardar sub-equation method (SSEM) which is used to attain several analytical solutions in the form of trigonometric and hyperbolic functions. …”
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Feasibility and Mechanical Strength Evaluation of New Customized Implants for Tibial Plateau Fractures Fixation by Meng Li, Mengmeng Hu, Xiaomeng Ren, Yi Gao, Longbo Du, Yu Jiang, Wei Zhang

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An Analytical Method for Fast Optimization of Multireservoir Hydropower Systems Operations Considering Risk‐Return Tradeoffs by S. Jamshid Mousavi, Kumaraswamy Ponnambalam

“…Abstract Long‐term multireservoir operations optimization is challenging for existing optimization methods such as stochastic dynamic programming (SDP) and implicit stochastic programming (ISP) suffering from excessive computing time requirements. More difficult is to tackle a risk‐based optimization problem and provide an efficient frontier of the objective function for multireservoir systems. …”
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The Optimal Portfolio Selection Model under g-Expectation by Li Li

“…Using different S-shaped utility functions and g-functions to represent the investors' different uncertainty attitudes towards losses and gains makes the model not only more realistic but also more difficult to deal with. …”
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Where have all the bishops gone? by J. E. Wehrmeyer

“…However, translations done in the latter half of the 20th century prefer the more generic term “overseer” or a functional equivalent. …”
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Neurovascular coupling alterations in type 2 diabetes: a 5-year longitudinal MRI study by Wen Qin, Xiaolu Zhang, Guangyang Ma, Jiayang Yang, Jiahui Lin, Quan Zhang

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Interjections as a Divergent Linguistic Category and Paralinguistic Interjections in Turkish: The Case of <cık> by İsa Sarı

“…Interjections occur outside of holistic grammatical structures and are more specific to spoken language. They function by conveying the speaker’s emotions, feelings, mental state, or attitude toward an event and can be positioned at various differentiating levels. …”
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Superiorly-based, preauricular tunneled insular flap for reconstruction of auricular defects by Délcio Aparecido Durso, Willian Segalin, Paolla Ribeiro Gonçalves, Marcella Ferreira Carvalho, Sérgio Domingo Bocardo, Flávia Freire Dantas

“…We report the case of a patient who presented with tumor lesions on more than one occasion in the anterior left ear and required surgical intervention to correct the defect generated by excision. …”
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Strategies for Gait Retraining in a Collegiate Runner with Transfemoral Amputation: A Case Report by Jillian Santer, Stephanie MacDonald, Katherine Rizzone, Shawn Biehler, Tanya Beiswenger

“…# Background More than fifty percent of people with limb amputations participate in sports or physical activity following amputation. …”
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Sine Half-Logistic Inverse Rayleigh Distribution: Properties, Estimation, and Applications in Biomedical Data by M. Shrahili, I. Elbatal, Mohammed Elgarhy

“…The statistical properties of the half-logistic inverse Rayleigh model are calculated, including the quantile function, moments, moment generating function, incomplete moment, and Lorenz and Bonferroni curves. …”
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A New Member of T-X Family with Applications in Different Sectors by Zubir Shah, Amjad Ali, Muhammad Hamraz, Dost Muhammad Khan, Zardad Khan, M. EL-Morshedy, Afrah Al-Bossly, Zahra Almaspoor

“…Some mathematical properties including hazard rate function, ordinary moments, moment generating function, and order statistics are discussed. …”
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A Latent Class Analysis of Nutrition Impact Symptoms in Cancer Survivors by Laura Keaver, Christopher McLaughlin

“…The EORTC-QLQ-C30 functioning and GHS scores were all significantly different between the three nutrition impact symptoms classes (<i>p</i> < 0.001). …”
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