Selective neoadjuvant therapy of rectal cancer patients (SELREC): study protocol for a European randomised controlled, open, multicentre non-inferiority trial by Markus W Büchler, Lukas Baumann, Peter Schirmacher, Christoph W Michalski, Markus K Diener, Dirk Jäger, Pascal Probst, Mohammed Al-Saeedi, Martin Schneider, Alexis Ulrich, Constantin Schwab, Anja Sander, Christina Klose, Christoph Kahlert, Hans-Ulrich Kauczor, Jürgen Debus, Rosa Klotz, Solveig Tenckhoff, Cosima Engerer, Kristin Uzun-Lang, Caroline Wild, Bruno C Köhler

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Constructing Real-Life Benchmarks for Community Detection by Rewiring Edges by Jing Xiao, Hong-Fei Ren, Xiao-Ke Xu

“…In order to make the performance evaluation of community detection algorithms more accurate and deepen our analysis of community structures and functional characteristics of real-life networks, a new benchmark constructing method is designed from the perspective of directly rewiring edges in a real-life network instead of building a model. …”
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The Climate-forming role of the production process of the forests of Ukraine by Platon Tretyak, Nelia Lukianchuk, Hryhoriy Krynytskyy

“…Forest vegetation plays a significant climate-regulating, oxygen-producing and moisture-producing function, which has not yet been sufficiently studied. …”
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Intraosseous endoscopic-assisted lesion debridement combined with free fibular vascularized transplantation for non-traumatic femoral head necrosis: A comparative study with core d... by Yalong Yang, Zhao Zhang, Yuanyuan Wei, Yang Li, Junliang Liu, Bo Wang, Shouhu Mi, Jintong Liu, Yongqiang Zhang, Yongming Guo, Meng Wu

“…Results A follow-up of more than 2 years was conducted for both groups of patients. …”
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Piloting a minimum data set (MDS) in english care homes: a qualitative study of professional perspectives on implementation and data use by Rachael E. Carroll, Nick Smith, Sinead ER Palmer, Jennifer Kirsty Burton, Adam Lee Gordon, Ann-Marie Towers, Stacey E. Rand, Freya Tracey, Anne Killett, Lucy Webster, Barbara Hanratty, Karen Spilsbury, Gizdem Akdur, Kaat De Corte, Julienne E. Meyer, Liz Jones, Claire Goodman

“…Abstract Background Digitalisation within English care homes offers potential to make more effective use of substantial data collected by staff during care planning and recording. …”
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A High-Throughput, Three-Dimensional Multiple Myeloma Model Recapitulating Tumor-Stroma Interactions for CAR-Immune Cell-Mediated Cytotoxicity Assay by Luanpitpong S, Janan M, Poohadsuan J, Rodboon N, Samart P, Rungarunlert S, Issaragrisil S

“…Through this assay, we demonstrated that CAF-like stromal cells impaired NK cell effector function in 2D culture and 3D spheroids, likely via paracrine signaling and physical barrier function. …”
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RESULTS OF COMPREHENSIVE STUDIES OF THE UNDERGROUND HYDROSPHERE WITHIN THE WESTERN SHOULDER OF THE BAIKAL RIFT (AS EXEMPLIFIED BY THE BAYANDAI – KRESTOVSKY CAPE SITE) by Konstantin Zh. Seminsky, Marina A. Tugarina

“…With the detail data on the Bayandai – Krestovsky Cape site, the above conclusions are more precisely determined, and it is generally concluded that the structural tectonic factor controls the hydrogeology of the region.The analysis of mineralization, composition, temperature and other characteristics of the underground waters (Fig. 3–6) show that at the low hierarchic level the NW boundary of the Obruchev interblock zone performs a function of a distinct hydrogeological barrier which represents the marginal suture of the Siberian platform. …”
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Using Evolutionary Computation on GPS Position Correction by Jung Yi Lin

“…In this paper, we proposed an evolutionary computation based technique to generate a correction function by two GPS receivers and a known reference location. …”
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Carbon Footprint Assessment on the Viability of Utilizing Brewer’s Spent Grain to Produce Biochar by Emily Newman, Nitin Nitin, Edward Spang, Glen Fox

“…The study employed a carbon footprint assessment approach to quantify the greenhouse gas (GHG) emissions associated with each disposal method, using one unprocessed kg of BSG as the functional unit. The results indicated that landfilling BSG generated approximately 3 kg CO₂ equivalent (CO₂e) per kg of unprocessed BSG, whereas biochar production reduced emissions to 1.18 kg CO₂e per kg of BSG. …”
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Recombinant human erythropoietin, and myocardial and cerebral acute ischemia: implications for clinical use. by Rafael Alejandro Gómez Baute, Liermis Dita Salabert, Yaney González Yglesias, Tamara Guerra Alfonso, Maritza Cabrera Zamora

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The Design of a Randomized Controlled Active Comparator Strategy Trial for Gout: Treat to Target Serum Urate Versus Treat to Avoid Symptoms by Daniel H. Solomon, Misti Paudel, Shravani Chitineni, Ana Fernandes, Tammy Pham, Shreya Billa, Chio Yokose, Kiara Tan, Julien J. Dedier, Maureen D. Dubreuil, John D. Fitzgerald, Sally L. Hodder, Tuhina Neogi, Michael H. Pillinger, Kevin R. Riggs, Kenneth G. Saag, Paul G. Shekelle, Zoe Tseng, Michael Toprover, David S. Wei, Michael J. Barry, Hyon K. Choi

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A high clinically translatable strategy to anti-aging using hyaluronic acid and silk fibroin co-crosslinked hydrogels as dermal regenerative fillers by Jialing Cheng, Zhiyang Chen, Demin Lin, Yanfang Yang, Yanjing Bai, Lingshuang Wang, Jie Li, Yuchen Wang, Hongliang Wang, Youbai Chen, Jun Ye, Yuling Liu

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The Role of Enjoining Good and Forbidding Evil in Shaping Social Life According to the Arba'in Nawawi by Damanhuri Basyir

“…Adopting a qualitative-descriptive approach through textual analysis, this study investigates more than fifty-one commentarial works on Al-Arba’in al-Nawawiyah. …”
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Analysis of the VIT1 Promoter Activity in Developing Arabidopsis thaliana Plants by Seckin Eroglu

“…Iron (Fe) deficiency in plants is one of the widespread problems limiting agricultural production. Generating crops more tolerant to Fe deficiency by genetic engineering or breeding is of great interest but challenging due to the knowledge gaps in general plant Fe homeostasis. …”
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Sustainable digital rent: a transformative framework for value dynamics in the digital age by Ünsal Özdilek

“…As digital platforms generate increasing amounts of information, expectations are increasingly met and shared more efficiently with all users, leading to a reduction in individual and general motivational, emotional, and cognitive engagement. …”
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Emerging Tumor Biomarkers in Pancreatic Cancer and Their Clinical Implications by Dimitrios Stefanoudakis, Maximos Frountzas, Nikolaos V. Michalopoulos, Dimitrios Schizas, Dimitrios Theodorou, Konstantinos G. Toutouzas

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Association of Trace Elements with Polycystic Ovary Syndrome in Women—A Case-Control Study by Tinkara Srnovršnik, Bojana Pinter, Milena Horvat, Janja Snoj Tratnik, Ingrid Falnoga, Darja Mazej, Ivan Verdenik, Irma Virant-Klun

“…Additional research is needed to provide more insights into the causality of the PCOS relationship with Mo and Cu in humans.…”
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Central Hemodynamics and Extravascular Lung Water Index in Varying Degrees of Community-Acquired Pneumonia by S. N. Avdeykin, I. N. Tyurin, N. A. Karpun, A. V. Salikov

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The Influence of Regional Anesthesia on the Systemic Stress Response by Tomasz Reysner, Katarzyna Wieczorowska-Tobis, Grzegorz Kowalski, Monika Grochowicka, Monika Pyszczorska, Aleksander Mularski, Malgorzata Reysner

“…Regional anesthesia (RA) has been shown to modulate this stress response more effectively than general anesthesia (GA) by blocking nociceptive signaling and attenuating the release of stress mediators. …”
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Analysis of thermo-hydro-mechanical coupling characteristics of artificial freezing process under seepage effects by Peipei Chen, Fengling Yin, Manqi Wang

“…The calculations show that: (1) As the seepage velocity increases, the convective heat transfer effect becomes more significant. The cooling effect generated by the freezing pipe is transmitted more rapidly through the soil, leading to the rapid expansion of the freezing front. …”
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