Suggested Topics within your search.
Suggested Topics within your search.
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1421
Research on the Style of Art Works based on Deep Learning
Published 2022-01-01“…The obvious texture characteristics of Chinese ink painting are selected as the input of the Cycle Generative Adversarial Network (CycleGAN) model builder, and the relativistic evaluator is employed to improve the model loss function and the adversarial loss function. …”
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1422
In silico assessment of genetic variation in KCNA5 reveals multiple mechanisms of human atrial arrhythmogenesis.
Published 2017-06-01“…In the tissue model, loss-of-function mutations facilitated breakdown of excitation waves at more physiological excitation rates than the wild-type, and the generation of early-after-depolarisations promoted unidirectional patterns of excitation. …”
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1423
Sensitivity analysis of activity scheduling parameters with a parameter optimization framework
Published 2024-09-01“…For example, changes in the population size and crossover function lead to more reliable results, while alteration in the number of generations and the mutation function have no effects on the outcomes. …”
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1424
AIF: Infrared and Visible Image Fusion Based on Ascending–Descending Mechanism and Illumination Perception Subnetwork
Published 2025-05-01“…The customized loss function consists of illumination loss, gradient loss, and intensity loss. …”
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1425
About the Gibbs-Appel equations for multibody systems
Published 2006-12-01“…The form proposed in this paper seems to be more clear and suitable for automatic generation of dynamical equations of motion. …”
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1426
Unique target binding by the C-terminal region of FHR1 provides a new perception of aHUS pathology
Published 2024-12-01“…By contrast, SCR5, the most C-terminal domain, was more relevant for C3b/C3d contact. Notably, wild-type FHR1LA selected C3d, while pathogenic aHUS-associated alterations FHR1SV selected C3b. …”
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1427
RNA interference of Aspergillus flavus in response to Aspergillus flavus partitivirus 1 infection
Published 2023-11-01“…The mutants of DCLs and AGOs infected by AfPV1 displayed more changes than RDRP mutants in response to the first three stresses. …”
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1428
A glyco-engineering approach for site-specific conjugation to Fab glycans
Published 2023-12-01“…In conventional ADCs, the drug molecules are chemically attached randomly to antibody surface residues (typically Lys or Cys), which can interfere with epitope binding and targeting, and lead to overall product heterogeneity, long-term colloidal instability and unfavorable pharmacokinetics. Here, we present a more controlled process for generating ADCs where drug is specifically conjugated to only Fab N-linked glycans in a narrow ratio range through functionalized sialic acids. …”
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1429
Novel photodynamic therapy using two-dimensional NiPS3 nanosheets that target hypoxic microenvironments for precise cancer treatment
Published 2022-12-01“…More crucial is that ·OH generation doesn’t need O2, and the O2 ·− can also work in a low O2 environment, and depleting oxygen in tumor cells. …”
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1430
MUC1 as a target for CAR‐T therapy in head and neck squamous cell carinoma
Published 2020-01-01“…Next, we constructed a second‐generation CAR and validated the cytotoxic function in vitro. …”
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1431
Transcriptomic and proteomic analysis reveals wall-associated and glucan-degrading proteins with potential roles in Phytophthora infestans sexual spore development.
Published 2018-01-01“…Despite being dormant, oospores contained a mostly normal complement of proteins required for core cellular functions. The RNA-seq data generated here and in prior studies were used to identify new housekeeping controls for gene expression studies that are more stable than existing normalization standards. …”
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1432
Analyses of the redistribution of work following cardiac resynchronisation therapy in a patient specific model.
Published 2012-01-01“…Regulation of regional work is essential for efficient cardiac function. In patients with heart failure and electrical dysfunction such as left branch bundle block regional work is often depressed in the septum. …”
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1433
The Arctan-X Family of Distributions: Properties, Simulation, and Applications to Actuarial Sciences
Published 2021-01-01“…The purpose of this paper is to investigate a new family of distributions based on an inverse trigonometric function known as the arctangent function. In the context of actuarial science, heavy-tailed probability distributions are immensely beneficial and play an important role in modelling data sets. …”
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1434
Quantitative SISCOM assessment for epileptogenic zone localization: insights from a multicenter study comparing two software platforms in temporal lobe epilepsy
Published 2025-04-01“…Both SPM and Analyze were concordant with the EZ reference standard in 14 cases (70%), showing no difference in sensitivity between the methods. However, SPM generated smaller, more localized clusters, while Analyze produced larger clusters with broader spatial coverage. …”
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1435
HpFBH3 transactivates HpCO7 via binding to the E-boxes in the promoter and may accelerate flower formation in pitaya
Published 2025-02-01“…In practice, accelerating flower formation and inducing more flowers usually result in higher yield. However, the genes for this purpose have not been well characterized in pitaya. …”
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1436
Unknown issues of digitalizing the tax domain
Published 2024-01-01“…The application of digital technologies in the tax domain represents a confirmation of modernization and the turning point in the development of the state's tax function. Digitalization establishes a new paradigm of managing the tax system and significantly changes the tax-political reality. …”
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1437
Acupressure for older people with cognitive impairment: a systematic review and meta-analysis of randomized controlled trials
Published 2025-04-01“…More studies on acupressure are needed to generate stronger and more robust evidence.Systematic review registrationPROSPERO, identifier: CRD42024556579.…”
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1438
G-TS-HRNN: Gaussian Takagi–Sugeno Hopfield Recurrent Neural Network
Published 2025-02-01“…For each neuron, the G-TS-HRNN associates an input fuzzy variable of <i>d</i> values, described by an appropriate Gaussian membership function that covers the universe of discourse. To build an instance of G-TS-HRNN(s) of size <i>s</i>, we generate <i>s</i> n-uplets of fuzzy values that present the premise of the Takagi–Sugeno system. …”
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1439
Surface-Related Multiple Suppression Based on Field-Parameter-Guided Semi-Supervised Learning for Marine Data
Published 2025-04-01“…The USNM is essentially an optimization operator that refines the underlying nonlinear mapping relationship between primaries and full wavefield data using the local wavefield feature loss function, thereby obtaining more accurate prediction results with respect to primaries. …”
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1440
PEGylated Elesclomol@Cu(Ⅱ)-based Metal‒organic framework with effective nanozyme performance and cuproptosis induction efficacy for enhanced PD-L1-based immunotherapy
Published 2024-12-01“…The peroxidase (POD)-like activity of ES@Cu(Ⅱ)-MOF generated an abundance of hydroxyl radicals (•OH) via a Fenton-like reaction, and its glutathione peroxidase (GSH-Px)-like activity converted Cu2+ into more toxic Cu+ ions to efficiently consume endogenous GSH. …”
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