Application of the New Mapping Method to Complex Three Coupled Maccari’s System Possessing M-Fractional Derivative by Jan Martinovic, Aziz Ur Rehman, Muhammad Bilal Riaz

“…Furthermore, the incorporation of M-Truncated derivative enables a more extensive exploration of solution patterns. …”
Get full text

Comparison of Machine Learning and Statistical Approaches of Detecting Anomalies Using a Simulation Study by Klaudia Lenart

“…Methodology: A simulation study was conducted, during which the data was generated using copula functions. For the purpose of generating different types of anomalies, marginal distributions of the variables were manipulated. …”
Get full text

Development of a Force Feedback Controller with a Speed Feedforward Compensator for a Cable-Driven Actuator by Juan Fang, Michael Haldimann, Bardia Amiryavari, Robert Riener

“…Future work will include the integration of the speed compensator into better feedback algorithms for more accurate force control.…”
Get full text

The Effect of Hydrogen Peroxide on Biogas and Methane Produced from Batch Mesophilic Anaerobic Digestion of Spent Coffee Grounds by Siham Sayoud, Kerroum Derbal, Antonio Panico, Ludovico Pontoni, Massimiliano Fabbricino, Francesco Pirozzi, Abderrezzaq Benalia

“…These findings highlight the potential of H₂O₂-pretreated SCG as a more efficient and readily available resource for sustainable waste management and renewable energy production.…”
Get full text

Can machine-learning algorithms improve upon classical palaeoenvironmental reconstruction models? by P. Sun, P. B. Holden, H. J. B. Birks, H. J. B. Birks

“…We found that the classical approaches are generally more robust, although they could also generate reconstructions which have modest statistical significance and therefore may be unreliable. …”
Get full text

Glucagon-like peptide-1 receptor agonists in neurodegenerative diseases: Promises and challenges by Zhi Dong Zhou, Lingxiao Yi, Karolina Popławska-Domaszewicz, Kallol Ray Chaudhuri, Joseph Jankovic, Eng King Tan

“…Experimental studies have shown that GRA have protective effects to modulate neuroinflammation, oxidative stress, mitochondrial and autophagic functions, and protein misfolding. Hence the compounds have generated enormous interest as novel therapeutic agents against NDs. …”
Get full text

Testing an inverse modeling approach with gradient boosting regression for stroke volume estimation using patient thermodilution data by Vasiliki (Vicky) Bikia, Dionysios Adamopoulos, Dionysios Adamopoulos, Dionysios Adamopoulos, Marco Roffi, Marco Roffi, Georgios Rovas, Stéphane Noble, Stéphane Noble, François Mach, François Mach, Nikolaos Stergiopulos

“…Stroke volume (SV) is a major indicator of cardiovascular function, providing essential information about heart performance and blood flow adequacy. …”
Get full text

Identification of the Cold-Related Genes COLD11 and OsCTS11 via BSA-seq and Fine Mapping at the Rice Seedling Stage by Bian Wu, Minghui Fu, Jinghua Du, Mengjing Wang, Siyue Zhang, Sanhe Li, Junxiao Chen, Wenjun Zha, Changyan Li, Kai Liu, Huashan Xu, Huiying Wang, Shaojie Shi, Yan Wu, Peide Li, Aiqing You, Lei Zhou

“…According to the reported functional variation of COLD11, Nipponbare (TCG + 3GCG)×2 presented more GCG repeats in the 1st exon than WD16343 (TCG + 3GCG), partially explaining the difference in cold tolerance between the parents. …”
Get full text

The AMD-associated genetic polymorphism CFH Y402H confers vulnerability to Hydroquinone-induced stress in iPSC-RPE cells by Angela Armento, Inga Sonntag, Ana-Cristina Almansa-Garcia, Merve Sen, Sylvia Bolz, Blanca Arango-Gonzalez, Ellen Kilger, Ruchi Sharma, Kapil Bharti, Rosario Fernandez-Godino, Berta de la Cerda, Simon J. Clark, Simon J. Clark, Simon J. Clark, Marius Ueffing

“…There has been, and continues to be, much discussion around the functional consequences of this Y402H polymorphism, whether the soluble FH protein confers its risk association, or if the cells expressing the protein themselves are affected by the genetic alteration. …”
Get full text

Bystander editing by adenine base editors impairs vision restoration in a mouse model of Leber congenital amaurosis by Seok-Hoon Lee, Jun Wu, Dongjoon Im, Gue-ho Hwang, You Kyeong Jeong, Hui Jiang, Seok Jae Lee, Dong Hyun Jo, William A. Goddard, III, Jeong Hun Kim, Sangsu Bae

“…Through AlphaFold-based mutational scanning and molecular dynamics simulations, we identified that the ABE8e-driven L43P mutation disrupts RPE65 structure and function. Our findings underscore the need for more stringent requirements in developing precise BEs for future clinical applications.…”
Get full text

Comparing a Guideline-Based Mobile Health Intervention Versus Usual Care for High-Risk Adolescents With Asthma: Protocol of a Randomized Controlled Trial by Tamara T Perry, Jessica H Turner, Ariel Berlinski, Larry A Simmons, Rita H Brown, Kaymon Neal, Sarah A Marshall, Xing He, Simon Chung, Andrew Brown, Horace J Spencer 3rd, Jiang Bian

“…The study has 3 aims: (1) examine the effectiveness of PEAKmAAP in reducing asthma morbidity, as measured by the Asthma Control Test (ACT) score, health care use, medication use, and lung function; (2) examine the effectiveness of PEAKmAAP in asthma self-efficacy and medication adherence; and (3) examine the impact of sharing PEAKmAAP-generated data with the primary care provider (PCP) for a subset of enrolled subjects. …”
Get full text

Optimized multi‐biometric enhancement analysis by Saliha Artabaz, Layth Sliman, Karima Benatchba, Mouloud Koudil

“…To do so, the study applies different functions that are generated using genetic programming (GP) on the 2000 multi‐biometric instances produced by the fusion of different biometric matching scores. …”
Get full text

A method for benchmarking genetic screens reveals a predominant mitochondrial bias by Mahfuzur Rahman, Maximilian Billmann, Michael Costanzo, Michael Aregger, Amy H Y Tong, Katherine Chan, Henry N Ward, Kevin R Brown, Brenda J Andrews, Charles Boone, Jason Moffat, Chad L Myers

“…Abstract We present FLEX (Functional evaluation of experimental perturbations), a pipeline that leverages several functional annotation resources to establish reference standards for benchmarking human genome‐wide CRISPR screen data and methods for analyzing them. …”
Get full text

A comprehensive review on the composition, processing methods, and sustainable utilization of tropical fruit seeds in food industry by Xuanyi Zhang, Jun Liang, Xiaojun Lin, Junzhe Chen, Xiaoyu Luo

“…However, considering they are still rich in nutritional and bioactive components, tropical fruit seeds are hidden jewelry that can be more extensively utilized in the food industry, such as in food processing, food preservation, and the formulation of functional foods. …”
Get full text

A nano-enabled structural GFRP composite for self-powered multi-sensing applications by Lampros Koutsotolis, Angelos Voudouris Itskaras, George Karalis, Alkiviadis S. Paipetis

“…With growing concerns around sustainability and energy consumption, the next generation of advanced composites needs to incorporate additional functionalities. …”
Get full text

PhosphoPep—a phosphoproteome resource for systems biology research in Drosophila Kc167 cells by Bernd Bodenmiller, Johan Malmstrom, Bertran Gerrits, David Campbell, Henry Lam, Alexander Schmidt, Oliver Rinner, Lukas N Mueller, Paul T Shannon, Patrick G Pedrioli, Christian Panse, Hoo‐Keun Lee, Ralph Schlapbach, Ruedi Aebersold

Get full text

A reduction in effective population size has not relaxed purifying selection in the human population of Eivissa (Balearic Islands) by Julen Aizpurua-Iraola, Elisa Marí-Cardona, Maria Barber-Olives, David Comas, Francesc Calafell

“…Whether this distinctiveness emerged from a differential demographic history, or rather from a bias for sampling in a small geographic region such as Eivissa, remains an open question, together with the understanding of the functional consequences of demography in the island. …”
Get full text

Plant-based chitosan for the development of biodegradable packaging materials by Adity Bahndral, Rafeeya Shams, Pintu Choudhary

“…The quantity of waste generated in a mushroom farm varies from 5–20 % of the total yielding quantity. …”
Get full text

The Mycobacterium tuberculosis Rv2745c plays an important role in responding to redox stress. by Amanda McGillivray, Nadia Abrahams Golden, Uma Shankar Gautam, Smriti Mehra, Deepak Kaushal

“…Our isogenic mutant, Mtb:ΔRv2745c, is significantly more sensitive to in vitro redox stress generated by diamide, relative to wild-type Mtb as well as to a complemented strain. …”
Get full text

Incremental learning with SVM for multimodal classification of prostatic adenocarcinoma. by José Fernando García Molina, Lei Zheng, Metin Sertdemir, Dietmar J Dinter, Stefan Schönberg, Matthias Rädle

“…The use of texture descriptors provides more salient discriminative patterns than the functional information used. …”
Get full text