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1141
Characterization of a long-term mouse primary liver 3D tissue model recapitulating innate-immune responses and drug-induced liver toxicity.
Published 2020-01-01“…Animal in vitro models enable back- and forward translation of in vitro and in vivo findings, bridge the gap between rodent in vivo and human in vitro scenarios, and ultimately support the interpretation of data generated with preclinical species and humans. Since mice are often used in drug development and physiologically relevant in vitro systems are lacking, we established, for the first time, a mouse liver model that encompasses primary parenchymal and non-parenchymal cells with preserved viability and functionality over three weeks. …”
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1142
Análise do valor na conformação de tailored-blanks Analysis of the value on forming of tailored blanks
Published 2008-01-01“…The objective of this work was the use of the Analysis of the Value methodology in order to obtain financial results that can propitiate a more competitive product, according to the analysis product functions. …”
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1143
Peptidylglycine alpha-amidating monooxygenase is important in mice for beta-cell cilia formation and insulin secretion but promotes diabetes risk through beta-cell independent mech...
Published 2025-06-01“…Despite these changes in beta cell function, βPamKO mice were not more susceptible to diet-induced hyperglycemia. …”
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1144
A Latent Class Analysis of Nutrition Impact Symptoms in Cancer Survivors
Published 2024-10-01“…The EORTC-QLQ-C30 functioning and GHS scores were all significantly different between the three nutrition impact symptoms classes (<i>p</i> < 0.001). …”
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1145
Health Care for the Elderly People
Published 2023-07-01“…More than 50 % expressed that the center's staff does not support the recovery process of the elderly and that activities aimed at the physical and mental health of the elderly are not planned. 56 % reported not being a health professional and 50 % highlighted that the functions in the gerontological center are not clearly defined <br /><strong>Conclusions:</strong> it is necessary to carry out training that contributes to improving the quality of care and attention of the elderly.…”
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1146
Characterisation of bovine leukocyte Ig-like receptors.
Published 2012-01-01“…Leukocyte Immunoglobulin-like receptors (LILR) are innate immune receptors involved in regulating both innate and adaptive immune functions. LILR show more interspecies conservation than the closely related Killer Ig-like receptors, and homologues have been identified in rodents, primates, seals and chickens. …”
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1147
Sustainable Nanotechnology and Artificial Intelligence to Empower Image-Guided Therapy for Precision Healthcare
Published 2025-01-01“…Nanotechnology has substantially advanced imaging, therapy, and clinical techniques, playing a crucial role in the development of sustainable functional materials in biomedical engineering. Nanoparticles, used as contrast agents in multimodal imaging, offer notable advantages due to their high surface area-to-volume ratio, enabling functionalization with targeting ligands for improved specificity and sensitivity. …”
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1148
Full-length transcriptomes of 25 grassland plant species
Published 2025-06-01“…Furthermore, 40.3% of the transcripts contained complete open reading frames (ORFs), while 31.4% had incomplete ORFs. More than 36.8% of the transcripts were identified as non-coding RNAs. …”
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1149
In Vitro Anthelmintic Activities of Khaya anthotheca and Faidherbia albida Extracts Used in Chad by Traditional Healers for the Treatment of Helminthiasis and In Silico Study of Ph...
Published 2024-01-01“…Docking studies were carried out using the Schrodinger Maestro software’s Glide module. The score function in the software was used to rank and group distinct possible adduct structures generated by molecular docking. …”
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1150
CITMIC: Comprehensive Estimation of Cell Infiltration in Tumor Microenvironment based on Individualized Intercellular Crosstalk
Published 2025-01-01“…The TME cell‐based features generated by analyzing melanoma data are effective in predicting prognosis and treatment response. …”
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1151
Analytical Support for the Waste Management Sector: A Review of Foreign Scientific Publications
Published 2025-06-01“…Each year, 2.01 billion tons of solid municipal waste are generated globally, averaging 0.74 kg per person. By 2050, global waste is expected to rise to 3.4 billion tons, exceeding the growth of the population more than twofold during the same period. …”
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1152
Tailored Food Recommendations in Facilitating Dietary Change: A Rule-Based Personalized Eating Solution
Published 2023-11-01“…In personalized nutrition solutions, dietary advice is more and more based on clinical biomarkers, genetics, and the gut microbiome. …”
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1153
Multipath2.0: Extending Multilayer Reproducible Pathway Models with Omics Data
Published 2025-01-01“…In the field of omics, multiple disciplines target the study of specific types of molecules, such as genomics. The support of more data sources in these analyses is becoming more crucial for understanding the interplay of biological systems. …”
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1154
Reducing Building Energy Performance Gap: Integrating Agent-Based Modelling and Building Performance Simulation
Published 2025-05-01“…Additionally, the Adjust model provided a more realistic representation of thermal comfort, reducing variability in the predicted mean vote (PMV) index from extreme values in the Base model to a more stable range in the Adjust model. …”
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1155
Observational partitioning of water and CO<sub>2</sub> fluxes at National Ecological Observatory Network (NEON) sites: a 5-year dataset of soil and plant components for spatial...
Published 2024-12-01“…Partitioning of CO<span class="inline-formula"><sub>2</sub></span> components, on the other hand, was found to be less robust and more dependent on prior knowledge of water use efficiency. …”
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1156
On the Modular Design Application for the Gas Turbine Sector: A Performance Optimization Approach in the Context of Industry 4.0
Published 2025-02-01“…Indeed, this study presents the functioning of the novel application, the different deployed components and their variables, such as the compressor efficiency, heat exchangers, or turbine stages, and the decision variable, e.g., the costs of generated energy. …”
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1157
Chemotranscriptomic analysis of 7-hydroxymatairesinol-related effects on MCF7 human breast tumor cells
Published 2023-11-01“…As a result, a panel of genes with altered expression is generated, which are analyzed by the functional linkage method using the international nomenclature of Gene Ontology (GO) linked to biological roles of genes/proteins.Results. …”
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1158
Performance evaluation of extreme value prediction methods for bridge traffic load effects
Published 2025-08-01“…Accurately determining the distribution functions of maximum values is crucial for assessing bridge safety under traffic loads. …”
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1159
Local management and governance improve natural resource incomes of communal conservancies in Namibia
Published 2025-06-01“…Support from NGOs remained critical to financial sustainability of conservancies and AGMs were important governance functions. Natural resource management and institutional governance facilitated income generation by Namibia's conservancies, but more emphasis on benefit distribution could increase socioeconomic impact. …”
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1160
Accelerating crystal structure search through active learning with neural networks for rapid relaxations
Published 2025-02-01“…Using this approach, we are able to effectively identify the most promising candidates for further evaluation using density functional theory (DFT). Our method not only reliably reduces computational costs by up to two orders of magnitude across the benchmark systems Si16, Na8Cl8, Ga8As8 and Al4O6 but also excels in finding the most stable minimum for the unseen, more complex systems Si46 and Al16O24. …”
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