QR Food Ordering System with Data Analytics by Chee-Chun Wong, Lee-Ying Chong, Siew-Chin Chong, Check-Yee Law

“…As the epidemic starts to slow down and Malaysians are more confident about containing the outbreak with the norm of vaccination, diners have been aching to return to dining rooms, with many restaurants functioning at full capacity, but staffing is an entirely different story. …”
Get full text

The gene signature linked to lactate metabolism predicts the prognosis and correlates with the immune status of head and neck squamous cell carcinoma by Jian Xiao, Wei Li, Guolin Tan, Ru Gao

“…Additionally, eight critical hub genes were identified, revealing significant differences in gene expression between risk score groups. Functional analyses demonstrated that the low-risk group exhibited a more favorable prognosis and enhanced immune characteristics. …”
Get full text

A data-driven group retrosynthesis planning model inspired by neurosymbolic programming by Xuefeng Zhang, Haowei Lin, Muhan Zhang, Yuan Zhou, Jianzhu Ma

“…Retrosynthetic planning, a part of computer-assisted synthesis planning, addresses this challenge by recursively decomposing molecules using symbolic rules and machine-trained scoring functions. However, current methods often treat each molecule independently, missing the opportunity to utilize shared synthesis patterns and repeat pathways, which may contribute from known synthesis routes to newly emerging, similar molecules, a notable challenge with AI-generated small molecules. …”
Get full text

Choice of activation protocol impacts the yield and quality of CAR T cell product, particularly with older individuals by Palak H Mehta, Gemma S Trollope, Patrick Leung, Shivali Savita Chinni, Anna Iasinskaia, Aaron J Harrison, Hannah Hughes‐Parry, Misty R Jenkins, Michael H Kershaw, Anthony Jaworowski, Clare Y Slaney, Rachel M Koldej, David S Ritchie, Kylie M Quinn

“…Results Older samples generated fewer, more differentiated CAR T cells than young samples, and the αCD3/CD28 mAb protocol exacerbated this, further reducing yield and quality. …”
Get full text

Plasma membrane-coated nanoparticles and membrane vesicles to orchestrate multimodal antitumor immunity by Yang Li, Toshiaki Yoshikawa, Yusuke Ito, Satoshi Inoue, Takahiro Nakashima, Noriko Nakamura, Tetsuya Matsukawa, Seiichi Ohta, Yuki Kagoya, Hitomi Kasuya, Mirei Kataoka, Haosong Zhang, Chitose Oneyama

“…Here, we hypothesized that the simultaneous input of more comprehensive signals would elicit more robust and durable effector T-cell functions.Methods We genetically engineered the leukemia cell line K562 to express BsAbs, costimulatory ligands, cytokines, and blocking antibodies against immune checkpoint molecules on the cell surface, from which we obtained plasma membrane fractions by mechanical homogenization and subsequent isolation steps. …”
Get full text

Piloting a minimum data set (MDS) in english care homes: a qualitative study of professional perspectives on implementation and data use by Rachael E. Carroll, Nick Smith, Sinead ER Palmer, Jennifer Kirsty Burton, Adam Lee Gordon, Ann-Marie Towers, Stacey E. Rand, Freya Tracey, Anne Killett, Lucy Webster, Barbara Hanratty, Karen Spilsbury, Gizdem Akdur, Kaat De Corte, Julienne E. Meyer, Liz Jones, Claire Goodman

“…Abstract Background Digitalisation within English care homes offers potential to make more effective use of substantial data collected by staff during care planning and recording. …”
Get full text

A High-Throughput, Three-Dimensional Multiple Myeloma Model Recapitulating Tumor-Stroma Interactions for CAR-Immune Cell-Mediated Cytotoxicity Assay by Luanpitpong S, Janan M, Poohadsuan J, Rodboon N, Samart P, Rungarunlert S, Issaragrisil S

“…Through this assay, we demonstrated that CAF-like stromal cells impaired NK cell effector function in 2D culture and 3D spheroids, likely via paracrine signaling and physical barrier function. …”
Get full text

Autophagic flux-lipid droplet biogenesis cascade sustains mitochondrial fitness in colorectal cancer cells adapted to acidosis by Xiaojie Liu, Xue Sun, Wenqing Mu, Yanan Li, Wenqing Bu, Tingting Yang, Jia Zhang, Rui Liu, Jiayu Ren, Jin Zhou, Peishan Li, Yufang Shi, Changshun Shao

“…Here, we show that colorectal cancer cells adapted to acidic microenvironment (CRC-AA) are more reliant on oxidative phosphorylation than their parental cells, and the acetyl-CoA in CRC-AA cells are generated from fatty acids and glutamine, but not from glucose. …”
Get full text

Effect of Post-Acute Kidney Injury Use of Renin-Angiotensin Inhibitors on Long-term Mortality and Major Adverse Kidney Events: A 5-year Retrospective Observational Cohort Study by Byorn W.L. Tan, Bryce W.Q. Tan, K. Akalya, Wei-Zhen Hong, Yi Da, Sanmay Low, Wan-Ying Ng, Horng-Ruey Chua

“…Although angiotensin-converting enzyme inhibitors (ACEis) or angiotensin receptor blockers (ARBs) have been widely used in proteinuric kidney disease to slow kidney function decline, the effect of ACEi/ARB use post-AKI on long-term kidney function remains unclear. …”
Get full text

Bridging the Gap: ChatGPT’s Role in Enhancing STEM Education by Lingfei Luan, Xi Lin, Yan Dai

“…The results demonstrate significant disparities between AI-generated (ChatGPT) and human input. Upon analyzing the grade fluctuations before and after receiving input, it was shown that students who received feedback from ChatGPT encountered a more significant decrease (median = –12) compared to those who received feedback from humans (median = –5). …”
Get full text

Halogencarbene-free Ciamician-Dennstedt single-atom skeletal editing by Shaopeng Liu, Yong Yang, Qingmin Song, Zhaohong Liu, Paramasivam Sivaguru, Yifan Zhang, Graham de Ruiter, Edward A. Anderson, Xihe Bi

“…Herein, we report a general methodology for the Ciamician-Dennstedt reaction using α-halogen-free carbenes generated in situ from N-triftosylhydrazones. This one-pot, two-step protocol enables the insertion of various carbenes, including those previously unexplored in C-D skeletal editing chemistry, into indoles/pyrroles scaffolds to access 3-functionalized quinolines/pyridines. …”
Get full text

The Support Educational Commitee Participation in the Pedagogical Approach of an Educational Integration by Angélica Fontana-Hernández, Karla Durán-Chacón, Viviana Martínez-Ramírez, Viviana Rojas-Molina, Adriana Vargas-Navarro

“…For this, the Basic Educational Division of the Center for Teaching and Research in Education, generated a concern of investigating the participation of the Committee of Educational Support in the process of educational integration, thus, determine the functions performed in the educational context, under the rules of the 7600 Equal Opportunity Act for people with disabilities, which is the entity that corresponds to regulate access to education by identifying the support required for students with educational needs and, advice and trains, administrative staff in schools both public and private in the country. …”
Get full text

Meta-Analysis of Interactions between Arbuscular Mycorrhizal Fungi and Biotic Stressors of Plants by Haishui Yang, Yajun Dai, Xiaohua Wang, Qian Zhang, Liqun Zhu, Xinmin Bian

“…In return, nematodes and fungal pathogens generated more reduction of root colonization in Non-Glomeraceae than in Glomeraceae. …”
Get full text

Analysis of Line Contact Elastohydrodynamic Lubrication with the Particles under Rough Contact Surface by Keying Chen, Liangcai Zeng, Juan Chen, Xianzhong Ding

“…The results show that the roughness morphology and the particles can affect the behavior of the EHL, the traction force on a square rough surface is smaller, and the soft particles have more advantages for improving the EHL performance.…”
Get full text

Uniform finite presentation for groups of polynomial growth by Philip Easo, Tom Hutchcroft

“…Let $G$ be a finitely generated infinite group with generators $a_1,\dots,a_k$. …”
Get full text

Early manifestations of replicative aging in the yeast Saccharomyces cerevisiae by Maksim I. Sorokin, Dmitry A. Knorre, Fedor F. Severin

“…Looking into the mechanism, we found that knockouts of genes responsible for mitochondriato-nucleus (retrograde) signaling, RTG1 or RTG3, significantly decrease the resistance of cells that generated more than four daughters, but not of the younger ones. …”
Get full text

Adopting activated carbons on the PET depolymerization for purifying r-TPA by Cho Woo Seok, Lee Joon Hyuk, Na Da Yun, Choi Sang Sun

“…This approach offers a promising solution for producing high-quality r-TPA, paving the way for more efficient and sustainable PET waste management strategies.…”
Get full text

Research on FTTR WLAN indoor wireless location algorithm based on frequency response by Zhifeng LONG, Jing ZHANG

“…Highly accurate and reliable indoor wireless positioning services have been widely used.In order to obtain good positioning accuracy, the design of positioning algorithms needs to be matched with wireless positioning facilities.fiber to the room (FTTR) is an indoor access network solution based on IEEE 802.11 ax, a new generation of wireless local area network (WLAN) standard.Compared with the existing Wi-Fi networks, FTTR has a much larger available band width.However, FTTR WLAN also lacks of a public valid data set to support localization functions, which makes the localization research based on FTTR scenarios face huge obstacles.In order to solve the above problems, firstly, a frequency response-based FTTR scene dataset generation method was proposed, which uses the existing Wi-Fi localization dataset to generate the frequency response matrix within the available band width of FTTR.Then, the parallel path principal component analysis (PCA) method was used to generate the classification matrix.And the generated dataset was trained using a fully connected neural network to improve the accuracy.The experimental results on the real measurement dataset show that the proposed localization algorithm can achieve a localization accuracy of less than 1 m, which is not only more accurate than the traditional location estimation algorithm, but also basically meets the fine-grained localization requirements for practical applications.…”
Get full text

Research on FTTR WLAN indoor wireless location algorithm based on frequency response by Zhifeng LONG, Jing ZHANG

“…Highly accurate and reliable indoor wireless positioning services have been widely used.In order to obtain good positioning accuracy, the design of positioning algorithms needs to be matched with wireless positioning facilities.fiber to the room (FTTR) is an indoor access network solution based on IEEE 802.11 ax, a new generation of wireless local area network (WLAN) standard.Compared with the existing Wi-Fi networks, FTTR has a much larger available band width.However, FTTR WLAN also lacks of a public valid data set to support localization functions, which makes the localization research based on FTTR scenarios face huge obstacles.In order to solve the above problems, firstly, a frequency response-based FTTR scene dataset generation method was proposed, which uses the existing Wi-Fi localization dataset to generate the frequency response matrix within the available band width of FTTR.Then, the parallel path principal component analysis (PCA) method was used to generate the classification matrix.And the generated dataset was trained using a fully connected neural network to improve the accuracy.The experimental results on the real measurement dataset show that the proposed localization algorithm can achieve a localization accuracy of less than 1 m, which is not only more accurate than the traditional location estimation algorithm, but also basically meets the fine-grained localization requirements for practical applications.…”
Get full text

Selective Multistart Optimization Based on Adaptive Latin Hypercube Sampling and Interval Enclosures by Ioannis A. Nikas, Vasileios P. Georgopoulos, Vasileios C. Loukopoulos

“…It prioritizes sampling points by leveraging the hypercubes generated through LHS and their corresponding interval enclosures, guiding the optimization process toward regions more likely to contain the global minimum. …”
Get full text