The Role of Inflammation in Diabetes: Current Concepts and Future Perspectives by Sotirios Tsalamandris, Alexios S Antonopoulos, Evangelos Oikonomou, George-Aggelos Papamikroulis, Georgia Vogiatzi, Spyridon Papaioannou, Spyros Deftereos, Dimitris Tousoulis

“…The role of obesity, adipose tissue, gut microbiota and pancreatic beta cell function in diabetes are under intensive scrutiny with several clinical trials to have been completed while more are in development. …”
Get full text

Tertiary lymphoid organs in wild boar exposed to a low-virulent isolate of African swine fever virus by Néstor Porras, José M. Sánchez-Vizcaíno, Antonio Rodríguez-Bertos, Aleksandra Kosowska, José Á. Barasona

“…Immunoexpresion of p72 observed in the inflammatory cells adjacent to TLOs/MALTs confirmed its development and reactivity generated by ASF attenuated isolates. Immunohistochemical evaluation, based on cellular composition (T and B lymphocytes), and histomorphometrical study revealed a more pronounced maturation of TLOs/MALTs in the LVI-HVI group. …”
Get full text

Neural induction in Xenopus: requirement for ectodermal and endomesodermal signals via Chordin, Noggin, beta-Catenin, and Cerberus. by Hiroki Kuroda, Oliver Wessely, E M De Robertis

“…Loss-of-function experiments with antisense morpholino oligos (MO) showed that the CNS that forms in mesoderm-less Xenopus embryos (generated by injection with Cerberus-Short [CerS] mRNA) required Chordin (Chd), Noggin (Nog), and their upstream regulator beta-Catenin. …”
Get full text

Extreme genetic fragility of the HIV-1 capsid. by Suzannah J Rihn, Sam J Wilson, Nick J Loman, Mudathir Alim, Saskia E Bakker, David Bhella, Robert J Gifford, Frazer J Rixon, Paul D Bieniasz

“…The capsid (CA) domain of the HIV-1 Gag protein is under strong pressure to conserve functional roles in viral assembly, maturation, uncoating, and nuclear import. …”
Get full text

Investigation on the Marine Corrosion Behavior and Mechanism of Fe₃O₄ Film Using ReaxFF-MD by CHEN Xiangrui, CHEN Yang, WANG Bing, GU Bin

“…In order to explore more deeply and comprehensively the intrinsic mechanisms of corrosion behavior of steel in the marine environment，the ReaxFF molecular dynamics (ReaxFF-MD) method was employed to study the marine corrosion behavior of Fe3O4 in steel passivation film under different NaCl contents，temperatures and strain conditions.By characterizing the surface corrosion morphology，testing the quality loss curve，number density curve，radial distribution function (RDF) curve and simulating the atomic structure evolution at the reaction interface，the process and differences of Fe3 O4 marine corrosion behavior under different conditions were analyzed，and the mechanisms of Fe3O4 marine corrosion and the influence of different factors were revealed at the atomic scale.Results showed that the marine corrosion of Fe3O4 went through three stages: the adsorption stage of water molecules on the surface of Fe3O4 substrate in marine environment，the rapid corrosion stage of substrate and the corrosion saturation stage.During the corrosion process，the increase in NaCl content in the marine environment promoted the adsorption of water molecules on the substrate surface，enhancing the interaction between substrate atoms and water molecules.Moreover，the increase in temperature would cause expansion deformation and enhance molecular motion，reducing the difficulty of bond breaking behavior of matrix atoms.External strain led to an increase in atomic bond lengths and a decrease in atomic coordination numbers within the Fe3O4 matrix，thereby exacerbating the corrosion process.Besides，when the external load was applied，the strain in the substrate increased with the progression of corrosion，and the defect concentration area was generated under high strain loading.…”
Get full text

Quantifying ventilatory control with 3% CO2 inhalation during exercise by Suhaib M. Hashem, Stanley M. Yamashiro, Takahide Kato, Takaaki Matsumoto, Vasilis Z. Marmarelis

“…We analyzed the time series data of their breath-by-breath PETCO2 and ventilation and generated a one input–one output model via the Laguerre expansion technique (LET) to construct the gain function and quantify the low (0.002–0.029 Hz) and high (0.03–0.15 Hz) frequency components using the weighted gain averages (WGA) as estimators of central and peripheral chemoreflex mechanisms respectively.Results3% CO2 inhalation caused a significant increase the high frequency WGAs at rest and in all levels of exercise except heavy exercise. …”
Get full text

PIPELINE INSPECTION GAUGE MAGNETIC SENSOR CALIBRATION USING TIME-HARMONIC ELECTROMAGNETIC FIELD by R.E. Vavilov, V.A. Goldberg

“…The choice of a harmonic function for the calibration magnetic field generation is also due to the convenience of the hardware implementation of the procedure for generating the input signal of a measure of magnetic quantity. …”

Multiscale Modeling of Meandering Fluvial Reservoir Architecture Based on Multiple-Point Geostatistics: A Case Study of the Minghuazhen Formation, Yangerzhuang Oilfield, Bohai Bay... by Jia Li, Chengyan Lin, Xianguo Zhang, Chunmei Dong, Yannan Wei, Wenyan Ning, Changcheng Han, Wei Guo

“…Moreover, the permeability function sets are more suitable than the porosity model for collaboratively simulating the permeability model. …”
Get full text

A fuzzy track-to-track association algorithm with dynamic time warping for trajectory-level vehicle detection by Siqi Wan, Huaqiao Mu, Ke Han, Taesu Cheong, Chi Xie

“…Aiming to address these issues in an integrated manner, this paper proposes a TTTA algorithm that comprehensively calculates the similarity between trajectories using multiple trajectory features through dynamic time warping (DTW) and Cauchy distribution degree of membership function. Multiple experimental datasets were generated by randomly sampling real AIS trajectory data into two trajectory data sources and adding random errors. …”
Get full text

An Experimental Study to Reduce the Fracture Pressure of High Strength Rocks Using a Novel Thermochemical Fracturing Approach by Zeeshan Tariq, Mohamed A. Mahmoud, A. Abdulraheem, Ayman Al-Nakhli, Mohammed BaTaweel

“…Breakdown pressure of the rock is a function of their tensile strength and in situ stresses acting on them. …”
Get full text

A U-net based reconstruction of high-fidelity simulation results for flow around a ship hull based on low-fidelity inviscid flow simulation by Dayeon Kim, Jeongbeom Seo, Inwon Lee

“…To create the training dataset, a variety of hull forms are generated from six baseline hull forms using parametric modification function techniques. …”
Get full text

Simultaneous Method for Solving Certain Systems of Matrix Equations with Two Unknowns by Predrag S. Stanimirović, Miroslav Ćirić, Spyridon D. Mourtas, Gradimir V. Milovanović, Milena J. Petrović

“…Numerical simulations are performed for various random initial states and comparison with the <i>Matlab</i>, linear programming solver linprog, and the pseudoinverse solution generated by the standard function pinv is given.…”
Get full text

What Matters in Psoriatic Arthritis: A Comparison of Patient and Clinician Perspectives by Philip J. Mease, M. Elaine Husni, Evan Siegel, Daniel E. Furst, Melissa Mcilraith, Vibeke Strand, M. Cameron Hay

“…Results Fifty‐one items describing PsA were generated. Thirty‐eight patients and 13 clinicians completed the last Delphi rating exercise. …”
Get full text

Root‐Zone Water‐Storage Capacity and Uncertainty: An Intrinsic Factor Affecting Agroecosystem Resilience to Drought by Nunzio Romano, Caterina Mazzitelli, Paolo Nasta

“…Abstract Mapping ecosystem function indicators helps identify areas susceptible to drought, heat stress, and reduced agricultural production. …”
Get full text

Estimating total species richness: Fitting rarefaction by asymptotic approximation by Yi Zou, Peng Zhao, Jan Christoph Axmacher

“…The function also enables users to visualize the estimation. …”
Get full text

Machine Learning Models for Frailty Classification of Older Adults in Northern Thailand: Model Development and Validation Study by Natthanaphop Isaradech, Wachiranun Sirikul, Nida Buawangpong, Penprapa Siviroj, Amornphat Kitro

“… Abstract BackgroundFrailty is defined as a clinical state of increased vulnerability due to the age-associated decline of an individual’s physical function resulting in increased morbidity and mortality when exposed to acute stressors. …”
Get full text

Synchronizing N Release from Organic Residues: Opportunities for Integrated Management of N by U. Singh, K.E. Giller, C.A. Palm, J.K. Ladha, H. Breman

“…The most widely accepted function of organic materials is improving the nutrient availability to crops by supplying N. …”
Get full text

Investigation on the arc erosion performance of Ag–Ta2AlC composite under air conditions by Xiaochen Huang, Liang Li, Jinlong Ge, Hao Zhao, Zijue Zhou

“…The Ta2AlC material is designed to enhance the performance of Ag-based electrical contact materials as a reinforcement phase. With a work function of 6.7192 eV, Ta2AlC demonstrated significantly higher values than reinforcement phase materials such as SnO2, ZrO2, and the commonly used MAX phase materials. …”
Get full text

An overview of the synthesis of coumarins via Knoevenagel condensation and their biological properties by Idriss Tchoffo Tchoupou, Melody H. Manyeruke, Sodeeq A. Salami, Charles I. Ezekiel, Pantaleon Ambassa, Jacqueline V. Tembu, Rui W.M. Krause, Bathelemy Ngameni, Xavier Siwe Noundou

“…For this reason, several initiatives primarily focus on developing new and more practical methods for synthesizing these compounds with the aim of addressing some of the pitfalls of traditional approaches. …”
Get full text

Effect of Cutting Tool Rake and Inclination Angles and Feeding Method on Cutting Force and Surface Quality in Single-point Threading by Rzgar Mhammed Abdalrahman, Sarkawt Rostam, Abdelhakim Deboucha

“…The process has problems of surface quality and power consumption because of lack of information regarding the effect of the tool’s rake and inclination angles and feeding method on surface quality and cutting forces as a function of cutting power. This study investigates influences of tool infeed method, rake, and inclination angles on surface quality of thread flanks and the cutting forces generated. …”
Get full text