SOX7: Autism associated gene identified by analysis of multi-Omics data. by Samantha Gonzales, Jane Zizhen Zhao, Na Young Choi, Prabha Acharya, Sehoon Jeong, Xuexia Wang, Moo-Yeal Lee

“…However, more than 99% of identified mutations are non-coding. …”
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Biomarkers for neurodegenerative diseases in regulatory decision‐making by the European Medicines Agency by Audrey M. M. Hermans, Elisabeth Bakker, Viktoriia Starokozhko, Loes den Otter, André J. A. Elferink, Angela Bradshaw, Lorenzo Guizzaro, Peter G. M. Mol, Anna M. G. Pasmooij

“…Collaboration and data‐sharing among stakeholders is vital in generating this evidence and enhancing the understanding and management of NDDs. …”
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Mental Health in the Age of Hyperconnectivity: A Crisis Hidden in Plain Sight by Sitara Ejaz, Hafiz Muhammad Haseeb Khaliq

“…Data indicates that individuals who spend more than three hours daily on social media face a 60% higher likelihood of developing anxiety or depressive symptoms 5. …”
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Prediction of dam deformation using adaptive noise CEEMDAN and BiGRU time series modeling by WANG Zixuan, OU Bin, CHEN Dehui, YANG Shiyong, ZHAO Dingzhu, FU Shuyan

“…【Method】The model uses sample entropy reconstruction and the K-means clustering algorithm to optimize the adaptive noise complete ensemble empirical mode decomposition with adaptive noise (CEEMDAN) process, generating multiple intrinsic mode functions (IMF). …”
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Sensing of Liver‐Derived Nicotinamide by Intestinal Group 2 Innate Lymphoid Cells Links Liver Cirrhosis and Ulcerative Colitis Susceptibility by Jing Shen, Zhen Li, Xiaoyu Liu, Mengqi Zheng, Peng Zhang, Yatai Chen, Qiuheng Tian, Wenyu Tian, Guanjun Kou, Yanyan Cui, Bowen Xu, Yunjiao Zhai, Weijia Li, Xiaohuan Guo, Ju Qiu, Chunyang Li, Ran He, Lixiang Li, Chunhong Ma, Yanqing Li, Xiuli Zuo, Detian Yuan, Shiyang Li

“…Mechanistically, the NAD+ salvage pathway regulates gut ILC2s in a cell‐intrinsic manner by supporting the generation of succinate, which fuels the electron transport chain to sustaining ILC2s function. …”
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Global disparities in access to hepatitis C medicines before and during the early phase of the COVID-19 pandemic: an ARIMA-based interrupted time series analysis by Nick Bansback, Mina Tadrous, Marie Paul Nisingizwe, Michael R Law, Bethany Hedt-Gauthier, Naveed Z Janjua, Katie J Suda

“…High-income countries purchased more units than other groups. In terms of geographic location, North America (124 144 per 100 000 HCV cases) and Europe (81 001 per 100 000 HCV cases) had the highest DAA sales over time; the newer generation of combination DAAs was mainly used in high-income countries. …”
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Low expression of CCKBR in the acinar cells is associated with insufficient starch hydrolysis in ruminants by Yan Cheng, Tianxi Zhang, Chao Yang, Kefyalew Gebeyew, Chengyu Ye, Xinxin Zhou, Tianqi Zhang, Ganyi Feng, Rui Li, Zhixiong He, Oren Parnas, Zhiliang Tan

“…A better understanding of the physiological mechanisms that regulate digestion patterns in ruminants could lead to an increased use of starch concentrates. Here we show more robust pancreatic exocrine function in adult goats (AG) than in neonatal goats (NG) by combining scRNA-seq and proteomic analysis. …”
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LcIMT1, a litchi inositol methyl transferase gene, is responsible for d-bornesitol biosynthesis and confers drought tolerance by Liang-Liang Huang, Xin-Ying Li, Fang-Fang Liu, Xu-Ming Huang, Ren-Fang Zeng, Farhat Abbas, Hui-Cong Wang

“…l-quebrachitol, also known as 2-O-methyl-l-chiro-inositol, is a common form of methylated cyclitol found in Litchi chinensis, accounting for more than half of the soluble sugars. Nonetheless, the biological function of l-quebrachitol is somewhat restricted. …”
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Study protocol for a randomized double-blinded placebo-controlled trial on ASA therapy for patients with chronic rhinosinusitis with nasal polyps, NSAID-exacerbated respiratory dis... by Sanna Toppila-Salmi, Sanna Toppila-Salmi, Sanna Toppila-Salmi, Annina Lyly, Annina Lyly, Viljami Salmi, Viljami Salmi, Mikko Nuutinen, Mikko Nuutinen, Michael Kilpiö, Michael Kilpiö, Tanzeela Hanif, Tanzeela Hanif, Tanzeela Hanif, Mikko Niemi, Mikko Niemi, Mikko Niemi, Anu Laulajainen-Hongisto, Lena Hafrén, Mika Mäkelä, Paula Kauppi, Paula Virkkula, Alma Helevä, Alma Helevä

“…Secondary measures include variations in nasal polyp scores, CRS symptom control, general HRQoL, work productivity loss, peak nasal inspiratory flow (PNIF) with or without acoustic rhinometry (ARM), olfactory function assessed by the Sniffin' Sticks identification test, spirometry, peak expiratory flow (PEF), and histopathological findings at the 12-month follow-up.DiscussionThe AirGOs Medical trial is expected to generate data on the therapeutic value and safety profile of ATAD in patients with coexisting severe CRSwNP, N-ERD, and asthma, potentially informing future clinical practice. …”
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Leisure, work and simultaneous study in distance and virtual students (Ocio, trabajo y estudio simultáneo de estudiantes en modalidad a distancia y virtual) by Leonardo Andrés Aguirre-Cardona, Isabel Rubio-Florido, Edwin Alberto Puerto-Rodríguez

“…  The studies, analysis, reflections and positions regarding the leisure-work relationship is not new and is current, although sometimes it is not tangible and visible at first glance, even more so when the young population in Colombia takes advantage of distance and virtual education to be able to work and generate income and thus pay for a study; Thus, it was sought to analyze the incidence of working and studying simultaneously in the leisure time and spaces of students in distance and virtual mode of the Minuto de Dios-Uniminuto University Corporation in Bogotá-Colombia. …”
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Experimental Study on Hydraulic Characteristics of Fish-friendly Culverts with Baffles by MAO Jing-qiao, LU Peng, GONG Yi-qing, GAO Huan, DAI Jie

“…The transient vortices formed had planes parallel to the fish’s spine and body axis, reducing energy loss during upstream movement and improving swimming efficiency through vortex energy transfer. This provided a more favorable flow environment for weak-swimming fish species. …”
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Proses Kreatif Komposisi Karawitan “Gesang” Sebagai Wujud Representasi Sosial by Vivi Euis Susanti, Tri Suhatmini

“…The findings indicate that Gesang achieves an aesthetically rich musical form and exemplifies how karawitan can function as an expressive medium responsive to contemporary cultural developments. …”
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HEMOPHILIA: ADVANCES IN TREATMENTS by Nurgül Karakaya

“…Another method is PEGylation, where one or more PEG chains are covalently linked to rFVIII or rFIX. …”
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Optimization design of liquid crystal-based reconfigurable intelligent surface-assisted indoor visible light communication systems by Lisu YU, Xinxin LÜ, Run ZHONG, Mingli ZHANG, Zhenghai WANG, Yuhao WANG

“…Owing to the nonconvexity of the objective function, it is first transformed into a multinomial fractional planning problem using the Lagrangian dual transform, making it more tractable. …”
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Unités Paysagères et services écosystémiques, l’exemple des récifs coralliens by Gilbert David, Émilie Mirault, Gwenaëlle Pennober, Christophe Révillion

“…Thus the reef is not only a natural capital but also a landscape composed of associated resources spaces generating specific ecosystem services. But the finance orientated trend for valuing the environment makes more and more weak this cross cutting view and drives to a deadlock. …”
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A meta-analysis of epigenome-wide association studies of ultra-processed food consumption with DNA methylation in European children by Joana Llauradó-Pont, Nikos Stratakis, Giovanni Fiorito, Evangelos Handakas, Alexander Neumann, Henrique Barros, Anne Lise Brantsæter, Kiara Chang, Leda Chatzi, Janine F. Felix, Regina Grazuleviciene, Vincent W. V. Jaddoe, Marianna Karachaliou, Marion Lecorguillé, Carla Lopes, Christopher Millett, Rosemary R. C. McEachan, Eleni Papadopoulou, Remy Slama, Eszter P. Vamos, Paolo Vineis, Martine Vrijheid, John Wright, Trudy Voortman, Mariona Bustamante, Oliver Robinson, Camille Lassale

“…Methods We conducted a meta-analysis of epigenome-wide association studies (EWAS) from a total of 3152 children aged 5–11 years from four European studies (HELIX, Generation XXI, ALSPAC, and Generation R). UPF consumption was defined applying the Nova food classification system (group 4), and DNA methylation was measured in blood with Illumina Infinium Methylation arrays. …”
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Grown up in the face of values. The subjective dimension of shaping values in human life. by Rafał Bodarski

“…More and more advanced technological progress, changes in the area of the life model, transforming economies from fossil fuels to renewable energy sources pose a number of challenges and the need to forecast the future. …”
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Inference of Impulse Responses via Bayesian Graphical Structural VAR Models by Daniel Felix Ahelegbey

“…Impulse response functions (IRFs) are crucial for analyzing the dynamic interactions of macroeconomic variables in vector autoregressive (VAR) models. …”
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Reaching new frontiers in nanoelectronics through artificial intelligence by Santhosh Sivasubramani, Themis Prodromakis

“…In materials discovery, AI aids in identifying new, more efficient and sustainable materials. In device design, it enhances the functionality and integration of components. …”
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Cell-Type-Specific Heat-Induced Changes in the Proteomes of Pollen Mother Cells and Microspores Provide New Insights into Tomato Pollen Production Under Elevated Temperature by Priya Thapa, Jun Guo, Kajol Pradhan, Dibya Thapa, Sudhakar Madhavarapu, Jing Zou, Jesse Potts, Hui Li, Joshua O’Hair, Chen Wang, Suping Zhou, Yong Yang, Tara Fish, Theodore W. Thannhauser

“…These HS-induced DAPs include proteases, antioxidant proteins, and proteins related to cell wall remodeling and the generation of pollen exine. Conclusions: HS induced more dynamic proteomic changes in meiotic PMCs compared to microspores, and the inter-varietal differences in the PMC proteomes align with the effects of HS on pollen productivity observed in the two varieties. …”
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