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1641
Utilizing small molecules to probe and harness the proteome by pooled protein tagging with ligandable domains
Published 2025-06-01“…These libraries unlock opportunities to explore the proteome with a versatile toolbox of small molecule probes designed to interact with the fused tags, allowing researchers to visualize protein localization, induce protein misfolding, manipulate protein-protein interactions, modulate protein stability, and more in a scalable, systematic manner. This review explores recent studies employing multifunctional domains at proteome scale, delving into how the associated chemical probes have been employed to enable insights into endogenous protein function, cellular processes, and disease mechanisms. …”
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1642
A Dynamic Load Modulation Power Amplifier with Ferroelectric-Based Tunable Matching Network
Published 2024-11-01“…Measurement studies of the dynamic load modulation power amplifier have demonstrated an efficiency of at least 50% at 8 dB back-off and more than 60% at peak power at 2.5 GHz. Furthermore, it was found that the modulator output voltage adjustment function on input power of the bias modulator affects the linearity of the output power. …”
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1643
Genetic clustering algorithm
Published 2020-01-01“…As a result, it has been found that stabilization of splitting into clusters is reached when the number of completed generations of evolution is 200 and more, and the population size is rather small: from 150 chromosomes (in this case no considerable amount of random-access store is required). …”
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1644
Operational monitoring of acoustic sensor networks
Published 2015-06-01“…The second method requires significantly more time control.…”
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1645
Research on multi-sensor fusion detection and tracking technology for autonomous-rail rapid transit tram
Published 2022-07-01“…Firstly, a millimeter-wave radar and LiDAR are used to perceive by single sensor, and the sensing results were merged by using a multi-source fusion algorithm, to generate more accurate detection results. Based on the false alarm filtering algorithm, the problem of false alarm probably caused by the millimeter wave radar was solved. …”
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1646
Strategies for choice of antiretroviral therapy in patients with HIV infection and concomitant cardiovascular disease: A review
Published 2025-01-01“…Comorbidity is gradually becoming one of the main drivers for premature mortality in HIV patients: in Russia, from 2007 to 2022, mortality rates in HIV patients not related to opportunistic infections increased more than twofold. People living with HIV have all the common cardiovascular risk factors, moreover, special attention should be paid to kidney function, since its impact on cardiovascular disease (CVD) risk is frequently underestimated. …”
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1647
Seeking Optimal Region-Of-Interest (ROI) Single-Value Summary Measures for fMRI Studies in Imaging Genetics.
Published 2016-01-01“…Our results show that four of these measures, particularly those that represent values from the top most-activated voxels within an ROI are more powerful at reliably detecting group differences and generating greater effect sizes than the others.…”
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1648
Boyer-Moore String Matching Algorithm and SHA512 Implementation for Jpeg/exif File Fingerprint Compilation in DSA
Published 2020-06-01“…Hash value is important element inside DSA to identify information data integrity using hash function to generate message digest. Jpeg/exif is image file format that produce by digital camera as in smartphone. …”
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1649
Structural strength analysis and optimization of converter lug based on Kriging model
Published 2022-07-01“…For typical rail transit converters, each static strength analysis with four working conditions costs at least 1 hour, and each random vibration analysis with one axis costs more than 8 hours. As a result, for using traditional engineering optimization methods to optimize the converter structure, the optimization efficiency will be severely limited, since these methods need to invoke a large amount of simulations as function evaluations. …”
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1650
MMFOSOM: A Novel Multi-objective Moth–Flame Optimization Algorithm Based on Self-Organizing Mapping
Published 2025-06-01“…However, in cases with multiple objectives, selecting the best solution becomes more complex, as these objective functions often conflict with one another. …”
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1651
Age-related changes in Kv4/Shal and Kv1/Shaker expression in Drosophila and a role for reactive oxygen species.
Published 2021-01-01“…We show that Kv4/Shal protein levels decline sharply from 3 days to 10 days, then more gradually from 10 to 40 days after eclosion. …”
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1652
Advancing Insights into Large-Artery Stiffening in Humans Through the Application of Multi-omics
Published 2024-07-01“…Aging and various pathologic states impair this cushioning function, a phenomenon known as large-artery stiffening (LAS). …”
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1653
Cyanidin-3-glucoside: targeting atherosclerosis through gut microbiota and anti-inflammation
Published 2025-06-01“…Cyanidin-3-glucoside (C3G), a water-soluble flavonoid abundant in pigmented fruits and vegetables, exhibits potent antioxidant, anti-inflammatory, and anti-hypertensive bioactivities. More importantly, C3G engages in bidirectional interactions with the gut microbiota. …”
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1654
Humidity measurements in carbon dioxide with Sensirion SHT85 humidity sensors under simulated Martian atmospheric conditions
Published 2025-06-01“…However, the SHT75 sensors from Sensirion used at that time are no longer in production and have been replaced by a new generation of sensors: SHT85. The SHT85 sensors are more precise than their predecessors, have a new sensor chip, and feature a PTFE membrane over the humidity-sensitive layer to protect the sensor from dust and liquids. …”
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1655
The Influence of the working fluid and Regenerator material on the Performance of the types Gamma Stirling Engine
Published 2022-12-01“…The engine's most notable features are minimal noise, vibration, and pollution, as well as its capacity to function with any external heat source, including biomass, solar energy, and industrial waste. …”
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1656
Comunicare la Malattia Renale Cronica
Published 2019-06-01“…Eady who discovered albumin in his urine at age of nine years, and subsequently received dialysis and a transplant for more than 50 years and at the same time developed a successful academic career as dermatologist. …”
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1657
Implementing self-healing N-policy queueing models and their impact on IoT design applications
Published 2024-12-01“…Additionally, we provide explicit expressions for the transient probabilities of the model, employing generating function methodology and Laplace transform techniques. …”
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1658
Fracture Initiation in Aluminum Alloys Under Multiaxial Loading at Various Low Strain Rates
Published 2025-07-01“…Among the considered fitting functions, an exponential function was selected as it provided the most accurate relation between the equivalent plastic strain at fracture and the corresponding stress state across different strain rates. …”
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1659
Drivers of business model innovation in micro and small enterprises: evidence from Egypt as an emerging economy
Published 2023-02-01“…This study ensures that BMI is a function of how resources can be deployed and configured dynamically to generate value.…”
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1660
Mechanism of Transcranial Magnetic Stimulation Therapy for Neuropathic Pain
Published 2024-12-01“…As a mature non-invasive neuromodulation technique, transcranial magnetic stimulation (TMS) can generate transient magnetic pulses penetrating through the skull, induce changes in cortical neuronal potentials, and affect the function and structure of the nervous system, which can not only alleviate NP-related symptoms, but also improve NP-related emotional disorders. …”
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