Optimization of multi-element geochemical anomaly recognition in the Takht-e Soleyman area of northwestern Iran using swarm-intelligence support vector machine by Hamid Sabbaghi, Seyed Hassan Tabatabaei, Nader Fathianpour

“…Recently, many machine learning approaches have been developed and employed to model and map multi-element geochemical anomalies, where the important hyperparameters are generally regulated through trial-and-error processes. …”
Get full text

Global connectivity and resilience in African Banking: Role of technology and regulation by Minyahil Alemu, Jayamohan M.K., Wondaferahu Mulugeta

“…Covering 21 African nations and five major global economies, we employ comovement analysis (2000–2023), generalized impulse response functions, and System-GMM (2010–2023). …”
Get full text

Gut microbiome composition and diversity of wild-caught and hatchery-bred milkfish (Chanos chanos) fry by Gardel Xyza L. Silvederio, Therese F. Javellana, Ande Bryle N. Genciana, Maria Alexandra G. Fontanilla, Rex Ferdinand M. Traifalgar, Fredson H. Huervana, Carmelo S. del Castillo

“…Despite numerous studies on gut microbiota of wild and cultured fish species, the diversity and functional roles of the milkfish fry gut microbiome remain poorly understood. …”
Get full text

COMPARATIVE ANALYSIS OF NO-REFERENCE MEASURES FOR DIGITAL IMAGE SHARPNESS ASSESSMENT by Y. I. Golub, F. V. Starovoitov, V. V. Starovoitov

“…All the functions first calculate local estimates in the neighborhood of every pixel, and then use the arithmetic mean as a generalized quality index. …”
Get full text

Multi-Objective Improved Differential Evolution Algorithm-Based Smart Home Energy Management System Considering Energy Storage System, Photovoltaic, and Electric Vehicle by Mina GhasemiGarpachi, Moslem Dehghani, Mokhtar Aly, Jose Rodriguez

“…Home energy management systems (HEMSs) are becoming increasingly popular as smart homes become more prevalent, along with their ability to reduce peak network loads and generate and store green energy locally. …”
Get full text

Normal stress on surface of mesenchymal stem cells boosts extracellular vesicle secretion and regenerative bioactivity by Chengmeng Bai, Huifang Ren, Feng Zhang, Dandan Li, Qingyu Feng, Ying Li, Ting Chen, Chengxu Li, Xuan Xiao, Hengrui Zhang, Liang Hu

“…Here, we present a user-friendly method to manipulate the extracellular mechanical microenvironment of umbilical cord-derived mesenchymal stem cells (MSCs), a promising cell type for generating sEVs with therapeutic benefits, to boost sEV secretion and regenerative bioactivity. …”
Get full text

Constructing a knee osteoarthritis transplant via the neutrality aggregation operators under spherical fuzzy Z-numbers framework by Shahzaib Ashraf, Maria Akram, Subrata Jana, Jungeun Kim, Ibrahim M. Hezam, Chiranjibe Jana

“…We first investigate the SFZˆN notion, their accuracy and scoring functions, and the fundamental ideas that underlie their work. …”
Get full text

Improved Translational Relevance of In Vitro Fibrosis Models by Integrating IOX2-Mediated Hypoxia-Mimicking Pathways by Manuel A. González Hernández, Jennifer Venhorst, Lars Verschuren, Karin Toet, Martien P. M. Caspers, Martine C. Morrison, Beatrice Coornaert, Gerard J. P. van Westen, Roeland Hanemaaijer

“…Here, the ability of a hypoxia-mimicking compound (IOX2) to more accurately reflect the human fibrotic phenotype on a functional level was investigated. …”
Get full text

Impact of metacarpal shortening on finger strength following non-surgical treatment of spiral and oblique metacarpal shaft fractures by Martina Nöbel, Daniel Muder

“…This study aimed to evaluate whether a shortening of more than 2 mm in spiral/oblique MSFs affects the strength of a single finger. …”
Get full text

The Relationship between Benthic Macroinvertebrate Assemblages and Water Quality Parameters in the Sanyati Basin, Lake Kariba, Zimbabwe by Peter Makumbe, Artwell Kanda, Tambudzai Chinjani

“…The results from CCA highlighted that S1 was generally associated with high pH, NH4-N, and TN, and Oligochaeta, Syrphidae, and Hydrophilidae families. …”
Get full text

A comparison of nucleosome organization in Drosophila cell lines. by Rebecca L Martin, John Maiorano, Greg J Beitel, John F Marko, Graham McVicker, Yvonne N Fondufe-Mittendorf

“…Further analysis of these regions identified 91 out of 16,384 possible heptamer sequences that showed differential nucleosomal occupation between cell lines, and 49 of the heptamers matched one or more known transcription factor binding sites. These results demonstrate that there is differential nucleosome positioning between these Drosophila cell lines and therefore identify a system that could be used to investigate the functional significance of differential nucleosomal positioning in cell type specification.…”
Get full text

Neurobiological emergentism: sentience as an emergent process and the experiential gap by Todd E. Feinberg

“…One of the most controversial and debated problems regarding the nature of sentience, is how to integrate the biology and neurobiology of sentience with the problem of the “explanatory gaps” that are proposed to arise between the functions of the nervous system as objectively and scientifically explained and sentience—or more generally consciousness—as it is subjectively experienced. …”
Get full text

INFORMATION MODELING OF ORGANIZATION OF BRIDGES’ CONSTRUCTION UNDER STOCHASTIC UNCERTAINTY OF TIME PARAMETERS by T. V. Bobrova, M. S. Ratanin, E. P. Timofeeva

“…Probabilistic graphs make it possible to obtain more justified timeframes for performing individual works, and even the entire project by proceeding a given level of reliability.Methods. …”
Get full text

Machines and Human Epistemology by T. S. Demin, K. G. Frolov

“…In this case, the condition of reliability is the only criterion of knowledge to which the functional states of machines can correspond in the case of certain tasks, in connection with which the problem of generality arises especially acutely.…”
Get full text

Short-term spheroid culture of primary colorectal cancer cells as an in vitro model for personalizing cancer medicine. by Maria Jeppesen, Grith Hagel, Anders Glenthoj, Ben Vainer, Per Ibsen, Henrik Harling, Ole Thastrup, Lars N Jørgensen, Jacob Thastrup

“…Chemotherapy treatment of cancer remains a challenge due to the molecular and functional heterogeneity displayed by tumours originating from the same cell type. …”
Get full text

Histone H1 plays a role in heterochromatin formation and VSG expression site silencing in Trypanosoma brucei. by Megan L Povelones, Eva Gluenz, Marcin Dembek, Keith Gull, Gloria Rudenko

“…In addition, depletion of histone H1 results in chromatin becoming generally more accessible to endonucleases in bloodstream but not in insect form T. brucei. …”
Get full text

Loss of RXFP2 and INSL3 genes in Afrotheria shows that testicular descent is the ancestral condition in placental mammals. by Virag Sharma, Thomas Lehmann, Heiko Stuckas, Liane Funke, Michael Hiller

“…Our results provide a molecular mechanism that explains the loss of testicular descent in afrotherians and, more generally, highlight how molecular vestiges can provide insights into the evolution of soft-tissue characters.…”
Get full text

Collaborative Playlists around the World: A Cross-Cultural User Study by So Yeon Park, Jin Ha Lee, Audrey Laplante, Xiao Hu, Blair Kaneshiro

“…With these findings we discuss primary similarities and differences across the studied cultures and highlight directions for future investigations to further elucidate how music platforms with CP functionalities—and social capabilities more generally—can better help users achieve their desired goals around music.…”
Get full text

A stable and biocompatible shortwave infrared nanoribbon for dual-channel in vivo imaging by Cheng Yao, Ruwei Wei, Xiao Luo, Jie Zhou, Xiaodong Zhang, Xicun Lu, Yan Dong, Ruofan Chu, Yuxin Sun, Yu Wang, Wencheng Xia, Dahui Qu, Cong Liu, Jun Ren, Guangbo Ge, Jinquan Chen, Xuhong Qian, Youjun Yang

Get full text

Screening and characterization of the scFv for chimeric antigen receptor T cells targeting CEA-positive carcinoma by Chengcheng Zhang, Linling Wang, Qianzhen Zhang, Junjie Shen, Xia Huang, Meiling Wang, Yi Huang, Jun Chen, Yanmin Xu, Wenxu Zhao, Yanan Qi, Yunyan Li, Yanjiao Ou, Zhi Yang, Cheng Qian

“…Therefore, this study aimed to identify the optimal scFv and investigate its biological functions to further optimize the therapeutic potential of CAR-T cells targeting CEA-positive carcinoma.MethodsWe screened four reported humanized or fully human anti-CEA antibodies (M5A, hMN-14, BW431/26, and C2-45), and inserted them into a 3rd-generation CAR structure. …”
Get full text