Transcriptomic and proteomic analysis reveals wall-associated and glucan-degrading proteins with potential roles in Phytophthora infestans sexual spore development. by Xiaofan Niu, Audrey M V Ah-Fong, Lilianna A Lopez, Howard S Judelson

“…Despite being dormant, oospores contained a mostly normal complement of proteins required for core cellular functions. The RNA-seq data generated here and in prior studies were used to identify new housekeeping controls for gene expression studies that are more stable than existing normalization standards. …”
Get full text

The Effect of “Carvacrol” on Ischemia-Reperfusion Injury in the Skeletal Muscles of Rats by Barış Mardin, Abdullah Özer, Başak Koçak, Ayşegül Küçük, Mustafa Hakan Zor, Şaban Cem Sezen, Mustafa Kavutçu, Mustafa Arslan, Gürsel Levent Oktar

“…Therefore, we contend that more experimental cohort investigations are needed to examine the impact of the Car molecule on preventing I/R injury.…”
Get full text

Performance Study on Zn-Doped α-FeOOH in Removing H2S from Blast Furnace Gas by Bin WANG, Xudong LIU, Yuran LI, Li LIU, Wenqing XU, Tingyu ZHU

“…In situ infrared spectroscopy analysis revealed that Zn functions as a catalyst component and also directly interacts with H2S to form ZnS. …”
Get full text

AI in Home Care—Evaluation of Large Language Models for Future Training of Informal Caregivers: Observational Comparative Case Study by Clara Pérez-Esteve, Mercedes Guilabert, Valerie Matarredona, Einav Srulovici, Susanna Tella, Reinhard Strametz, José Joaquín Mira

“… BackgroundThe aging population presents an accomplishment for society but also poses significant challenges for governments, health care systems, and caregivers. Elevated rates of functional limitations among older adults, primarily caused by chronic conditions, necessitate adequate and safe care, including in-home settings. …”
Get full text

Novel Klebsiella pneumoniae and Pseudomonas aeruginosa MAPS vaccine combining O polysaccharides and pathogen-specific proteins by Mohammed N. Amin, James E. Sinclair, Brittany Curtis, Lada Sycheva, Heather Fox, Myeong-Jin Choi, Surekha Shridhar, Jacqueline Kolasny, Joseph Nkeze, Ethel Apolinario, Sang Hyun, Nicolas Hegerle, Shaichi Sen, Jasnehta Permala Booth, Mark Leney, Deborah Molrine, Greg Saia, Marcela Pasetti, Teresa Broering, Francis Michon, Richard Malley, George R. Siber, Sharon M. Tennant, Donna Ambrosino, Raphael Simon, Alan Cross

“…The use of pathogen-relevant proteins that may contribute to vaccine efficacy in place of the more traditional carrier proteins is a novel concept. …”
Get full text

CD81-guided heterologous EVs present heterogeneous interactions with breast cancer cells by Elena Gurrieri, Giulia Carradori, Michela Roccuzzo, Michael Pancher, Daniele Peroni, Romina Belli, Caterina Trevisan, Michela Notarangelo, Wen-Qiu Huang, Agata S. A. Carreira, Alessandro Quattrone, Guido Jenster, Timo L. M. Ten Hagen, Vito Giuseppe D’Agostino

“…Conclusions This study highlights the quantitative aspects underlying the creation of a platform for secreted heterologous EVs and shows the limits of single receptor-ligand interactions behind EV-cell engagement mechanisms, which now become the pivotal step to predict functional tropism and design new generations of EV-based nanovehicles.…”
Get full text

Phosphoglucomutase A-mediated metabolic adaptation is essential for antibiotic and disease persistence in Mycobacterium tuberculosis by Taruna Sharma, Shaifali Tyagi, Rahul Pal, Jayendrajyoti Kundu, Sonu Kumar Gupta, Vishawjeet Barik, Vaibhav Kumar Nain, Manitosh Pandey, Prabhanjan Dwivedi, Bhishma Narayan Panda, Yashwant Kumar, Ranjan Kumar Nanda, Samrat Chatterjee, Amit Kumar Pandey

“…These insights are crucial for developing novel, shorter, and more effective anti-tuberculosis strategies.IMPORTANCEThis study for the first time investigated the role of metabolic enzyme phosphoglucomutase A (pgmA) in Mycobacterium tuberculosis (Mtb), revealing its crucial functions as a toggle switch between biosynthesis and growth. …”
Get full text

Quantitative SISCOM assessment for epileptogenic zone localization: insights from a multicenter study comparing two software platforms in temporal lobe epilepsy by Carla Oliveira Young, Brunno Machado de Campos, Edna Marina de Souza, Sergio Querino Brunetto, Maria Julia de Oliveira Santos Gualberto, Leonardo Alexandre-Santos, Marcos Geraldo Merichelo de Oliveira, Marina Koutsodontis Machado Alvim, Fernando Cendes, Elba Etchebehere, Lauro Wichert-Ana, Bárbara Juarez Amorim

“…Both SPM and Analyze were concordant with the EZ reference standard in 14 cases (70%), showing no difference in sensitivity between the methods. However, SPM generated smaller, more localized clusters, while Analyze produced larger clusters with broader spatial coverage. …”
Get full text

Orchard variable-rate spraying method integrating GNSS and wind-excited audio-conducted leaf area density by Hangxing Zhao, Hangxing Zhao, Hangxing Zhao, Shenghui Yang, Shenghui Yang, Shenghui Yang, Wenwei Li, Wenwei Li, Han Feng, Han Feng, Shijie Jiang, Shijie Jiang, Weihong Liu, Weihong Liu, Jingbin Li, Yongjun Zheng, Yongjun Zheng, Songchao Zhang

“…Based on this, a method was established for generating prescription maps that integrate spatial positioning and canopy density information. …”
Get full text

HpFBH3 transactivates HpCO7 via binding to the E-boxes in the promoter and may accelerate flower formation in pitaya by Xiaowei Cai, Ling Xiao, Xiangmei Nie, Qiandong Hou, Sulin Wen, Kun Yang, Xiaopeng Wen

“…In practice, accelerating flower formation and inducing more flowers usually result in higher yield. However, the genes for this purpose have not been well characterized in pitaya. …”
Get full text

Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study by Adrian Edwards, Ridhi Agarwal, Janine Bates, Alison Bray, Sarah Milosevic, Emma Thomas-Jones, Michael Drinnan, Marcus Drake, Peter Michell, Bethan Pell, Haroon Ahmed, Natalie Joseph-Williams, Kerenza Hood, Yemisi Takwoingi, Chris Harding

“…Our findings emphasise the importance of LUTS being managed in primary care where possible, as in addition to cost savings and reduced waiting times, this is a more accessible option for patients, who tend to be more comfortable and confident being treated by familiar clinicians or in more familiar environments. …”
Get full text

Advancements in sorption-enhanced steam reforming for clean hydrogen production: A comprehensive review by Ahmad Salam Farooqi, Abdelwahab N. Allam, Muhammad Zubair Shahid, Anas Aqil, Kevin Fajri, Sunhwa Park, Omar Y. Abdelaziz, Mahmoud M. Abdelnaby, Mohammad M. Hossain, Mohamed A. Habib, Syed Muhammad Wajahat ul Hasnain, Ali Nabavi, Mingming Zhu, Vasilije Manovic, Medhat A. Nemitallah

“…The review outlines the potential of SE-SMR to offer more efficient hydrogen production, with the added benefit of in situ carbon capture simplifying the process design. …”
Get full text

Unveiling the Therapeutic Potential: Targeting Fibroblast-like Synoviocytes in Rheumatoid Arthritis by Siran Yue, Junyu Fan, Duoli Xie, Chunhao Cao, Zhuqian Wang, Jie Huang, Fang Qiu, Xu Yang, Dongyi He, Aiping Lu, Chao Liang

“…A deeper understanding of the molecular and functional heterogeneity of FLS may pave the way for more effective and precise therapeutic interventions in RA.…”
Get full text

PDGF-BB overexpressing dental pulp stem cells improve angiogenesis in dental pulp regeneration by Wentao Jiang, Wentao Jiang, Wentao Jiang, Wentao Jiang, Shuhan Duan, Shuhan Duan, Shuhan Duan, Shuhan Duan, Weiping Li, Huijiao Yan, Huijiao Yan, Huijiao Yan, Huijiao Yan, Chenli Si, Chenli Si, Chenli Si, Ningwei Xu, Ningwei Xu, Ningwei Xu, Ningwei Xu, Yishuai Li, Yishuai Li, Yishuai Li, Yishuai Li, Wenjie Zhang, Wenjie Zhang, Wenjie Zhang, Wenjie Zhang, Shensheng Gu, Shensheng Gu, Shensheng Gu, Shensheng Gu

“…In vivo transplants generated more vascular structures containing CD31 (+) endothelia. …”
Get full text

Systematic metabolic engineering enables highly efficient production of vitamin A in Saccharomyces cerevisiae by Yi Shi, Shuhuan Lu, Xiao Zhou, Xinhui Wang, Chenglong Zhang, Nan Wu, Tianyu Dong, Shilong Xing, Ying Wang, Wenhai Xiao, Mingdong Yao

“…Vitamin A is a micronutrient critical for versatile biological functions and has been widely used in the food, cosmetics, pharmaceutical, and nutraceutical industries. …”
Get full text

eCBT-I dialogue system: a comparative evaluation of large language models and adaptation strategies for insomnia treatment by Xueying Bao, Xingyu Zhu, Dongren Yang, Hao Lou, Ruoyun Wang, Yutong Wu, Wenhui Li, Yu Xia, Li Zeng, Yingying Pan, Xiqin Wang, Xian Zhang, Cheng Ling, Youhui Ling, Yan Zhang, Qi Zhao, Mei Yang

Get full text

Improved estimation of two-phase capillary pressure with nuclear magnetic resonance measurements via machine learning by Oriyomi Raheem, Misael M. Morales, Wen Pan, Carlos Torres-Verdín

“…By predicting vector functions from vector input features, we effectively reduced prediction errors. …”
Get full text

Emerging Diagnostic Approaches for Musculoskeletal Disorders: Advances in Imaging, Biomarkers, and Clinical Assessment by Rahul Kumar, Kiran Marla, Kyle Sporn, Phani Paladugu, Akshay Khanna, Chirag Gowda, Alex Ngo, Ethan Waisberg, Ram Jagadeesan, Alireza Tavakkoli

“…Point-of-care ultrasound and portable diagnostic devices have expanded real-time imaging and functional assessment capabilities across diverse clinical settings. …”
Get full text

Effects of pharmacological and non-pharmacological interventions for the management of sleep problems in people with fibromyalgia: a multi-methods evidence synthesis by Mari Imamura, Clare Robertson, Jemma Hudson, Daniel Whibley, Lorna Aucott, Katie Gillies, Marcus Beasley, Martin J Stevens, Paul Manson, Debra Dulake, Abhishek Abhishek, Nicole KY Tang, Gary J Macfarlane, Miriam Brazzelli

“…All items were examined and systematically categorised into conceptual health domains according to the aspect they aimed to capture; however, where appropriate, items were coded to more than one domain. Domains were generated inductively from the identified individual items and were informed by terms and definitions contained in the Sleep Foundation Dictionary and the World Health Organization International Classification of Functioning, Disability and Health. …”
Get full text

Characterization of FosA13, a novel fosfomycin glutathione transferase identified in a Morganella morganii isolate from poultry by Runzhi Zhang, Runzhi Zhang, Yan Yu, Yan Yu, Lulu Huang, Susu Chen, Ruxi Hu, Xiuxiu Wang, Dawei Huang, Chunhan Song, Junwan Lu, Qiyu Bao, Qiyu Bao, Qiyu Bao, Qiyu Bao, Yunliang Hu, Pengfei Jiang, Wei Pan

“…This protein shares the highest aa identity of 55.6% with the functionally characterized protein FosA and has all the essential functional residues of FosA proteins. …”
Get full text