Screening and characterization of the scFv for chimeric antigen receptor T cells targeting CEA-positive carcinoma by Chengcheng Zhang, Linling Wang, Qianzhen Zhang, Junjie Shen, Xia Huang, Meiling Wang, Yi Huang, Jun Chen, Yanmin Xu, Wenxu Zhao, Yanan Qi, Yunyan Li, Yanjiao Ou, Zhi Yang, Cheng Qian

“…Therefore, this study aimed to identify the optimal scFv and investigate its biological functions to further optimize the therapeutic potential of CAR-T cells targeting CEA-positive carcinoma.MethodsWe screened four reported humanized or fully human anti-CEA antibodies (M5A, hMN-14, BW431/26, and C2-45), and inserted them into a 3rd-generation CAR structure. …”
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Microstructural transformation for robust and high-efficiency Zintl thermoelectrics by Meng Jiang, Qinghua Zhang, Siyuan Zhang, Ming Liu, Yuntian Fu, Zhiyuan Zhang, Xin Ai, Bohayra Mortazavi, Lianjun Wang, Qihao Zhang, Denys Makarov, Wan Jiang

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Computational modelling of immunological mechanisms: From statistical approaches to interpretable machine learning by María Rodríguez Martínez, Matteo Barberis, Anna Niarakis

“…To conclude the workshop, a round table was organized to foster discussions on the existing challenges and chart a roadmap for the development of the next generation of computational models dedicated to investigating the cellular and molecular functions that underlie the immune system.…”
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Microstructural transition from ZrO₂ to Zr–Al intermetallics and property evolution in AA5051 composites by G. Anbuchezhiyan, G. Ananth, Vignesh M, K. Logesh, Nabisab Mujawar Mubarak, Elango Natarajan

“…AA5051 is lightweight and has excellent corrosion resistance, but it loses strength at higher temperatures as magnesium atoms diffuse more readily within the aluminium matrix, reducing the uniformity of the solid solution and weakening the alloy's strengthening mechanism. …”
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Increasing the capacity of electric grids based on the integration of meteorological data by M. Ya. Kletsel, E. V. Petrova, S. S. Girshin, V. A. Krivolapov, V. N. Goryunov, V. M. Trotsenko

“…The efficient and sustainable functioning of energy systems is a critical element for supplying of electricity necessary to maintain the vital functions of modern society. …”
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A data-mining analysis of host solute carrier family proteins in SARS-CoV-2 infection with reference to brain endothelial cells and the blood-brain barrier in COVID-19 by Talia Fradkin, Rainald Schmidt-Kastner

“…Literature searches for host SLCs revealed involvement of a subset of SLCs in infection mechanisms for SARS-CoV-2 and more broadly for other viruses. N = 17 host ABCs were found in brain endothelial cells where they may serve as efflux transporters.DiscussionThis hypothesis-generating work proposes a set of N = 80 host SLCs expressed in endothelial cells as contributors to BBB impairment after SARS-CoV-2 infection. …”
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In‐Sensor Computing‐Based Smart Sensing Architecture Implemented Using a Dual‐Gate Metal‐Oxide Thin‐Film Transistor Technology by Tengteng Lei, Yushen Hu, Xinying Xie, Runxiao Shi, Man Wong

“…Compatibility of the proposed architecture with functionally distinct elements for sensing, memory, and computing removes the restrictive demand for a single element simultaneously capable of all, thus making this architecture more generally applicable to a wider range of sensors and usage scenarios. …”
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Investigating age-related muscle force adaptations in males and females during sit-to-walk transition motion using EMG-informed modeling by Zakia Hussain, Alpha Agape Gopalai, Siti Anom Ahmad, Mazatulfazura Sf Binti Salim, Darwin Gouwanda, Pei-Lee Teh

“…Moreover, females exhibited more pronounced age-related muscle force changes than males during gait initiation. …”
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Spatial-Spectral Linear Extrapolation for Cross-Scene Hyperspectral Image Classification by Lianlei Lin, Hanqing Zhao, Sheng Gao, Junkai Wang, Zongwei Zhang

“…Therefore, a model needs to be trained on one or more source domains (SD) and achieve robust domain generalization (DG) performance on an unknown target domain (TD). …”
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The Actualisation of Regional Capacity Educational Space Based on Cluster Interaction: The Aspect of Formation of Training Health Culture by V. A. Fedorov, K. V. Chedov

“…The system component of the approach involves the consideration of the object (organisation, pedagogical system, educational space, etc.) not as a simple sum of any separate components, but as a single functional whole that has its own qualities distinguishable from the qualities of its individual parts. …”
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Development and Comparison of Interrupt-Based and Analog-to-Digital Converter Algorithms for Seed Counting in Precision Planters by A. Ghaffarnezhad, H. Navid, H. Karimi

“…IntroductionImproving field operations through precise spot planting rates depends on the accurate functioning of seed flow sensors within the working rows. …”
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AI-powered literature search: some observations and concerns by Farooq Azam Rathore, Fareeha Farooq

“…A brief overview of some tools that perform these functions is mentioned in Table I. However, in our role as physicians, faculty and researchers who have been using these tools for more than a year for various tasks including AI-powered literature search we have some concerns that need to be highlighted Recommending articles from the predatory journals We have noticed that some of the articles that these tools recommend are from predatory journals. …”
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Mo-W₁₈O₄₉/ZnIn₂S₄ Composites Synthesized by Metal Doping for Photocatalytic Hydrogen Evolution by Ruiqin Sun, Yue Liu, Jiamei Yang, Tuoya Wuren, Haochen Duan, Zhibing Tan, Shiyong Yu

“…Utilizing two or more semiconductor materials with distinct geometric and electronic energy arrangements at the nanoscale to construct heterostructures is an important means for developing high-performance catalysts for photocatalytic hydrogen evolution. …”
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The Comprehensive Effect of Depression, Anxiety, and Headache on Pain Intensity and Painkiller Use in Patients with Headache Analyzed by Unsupervised Clustering Using Machine Learn... by Jong-Ho Kim, Minha Ahn, Jong-Hee Sohn, Sung-Mi Hwang, Jae-Jun Lee, Young-Suk Kwon

“…The clusters demonstrated significant differences which can help better characterize patients based on their psychological and functional impact.…”
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Mutational Spectrum Analysis of Seven Genes Associated with Thyroid Dyshormonogenesis by Xi Chen, Xiaohong Kong, Jie Zhu, Tingting Zhang, Yanwei Li, Guifeng Ding, Huijuan Wang

“…Fifteen (71%) patients carried 2 or more DUOX2 (14) or DUOXA2 (1) variants. The genetic basis of DH in nine (43%) patients harboring biallelic or triallelic pathogenic variants was resolved. …”
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Comparative Study of the Nutritional Value, Phytochemicals, and Sensory Quality of Flakes Prepared Using Elicited and Non-Elicited Cowpea Sprout Flours by Setyaningrum Ariviani, Galih Poetri Nastiti, Nurul Hidayati Sholihin, Gusti Fauza, Siswanti Siswanti

“…Germination without and with elicitation using 50 mM NaCl or 250 ppm Na-alginate generated cowpea sprout flours with the levels of protein, total phenolic compounds (TPC), total flavonoid compounds (TFC), radical scavenging activity (RSA), and ferric reducing antioxidant power (FRAP), as well as functional properties that significantly higher than that of cowpea seed flour. …”
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TopoRSNet: A Unique Approach to Maintaining Topological Features for Digital Rock Image Rescaling With Minimal Quality Degradation by Kunning Tang, Yufu Niu, Ying DaWang, Vanessa Robins, Peyman Mostaghimi, Mark Lindsay, Ryan T. Armstrong

“…Typically, a single high‐resolution 3D micro‐CT image can be extremely large with more than 1010 voxels, and in the case of dynamic scans, hundreds of such large images will be generated, posing challenges in storage, downstream analysis, modeling, and their application to deep learning. …”
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Competitive Roles of DNRA and Denitrification on Organic Nitrogen Dynamics in Partially Saturated Soil‐Water Systems by Lecheng Liu, Tianyuan Zheng, Yingying Qiu, Yujie Hao, Haoran Ma, Xilai Zheng, Alberto Guadagnini

“…The rate of DNRA is documented to be (a) significantly faster in loam than in sandy loam, due to dissolved carbon release from loam aggregates, and (b) more effective in the presence of amino acid than urea in the natural soil, due to the role of amino acid as carbon source. …”
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Improving outcomes for people with autism spectrum disorders by reducing mental health problems: the IAMHealth research programme including one RCT by Emily Simonoff, Gillian Baird, Bryony Beresford, Tony Charman, Martin Knapp, Andrew Pickles, Carol Povey, Tom Purser, Paramala Santosh, Vicky Slonims, Stephen Scott

“…Adolescent adaptive functioning was predicted not only by early childhood autistic symptoms and IQ and ADHD symptoms. …”
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Cembranoid Diterpenes from South China Sea Soft Coral <i>Sarcophyton crassocaule</i> by Hanyang Peng, Yanbo Zeng, Rui Zhang, Li Yang, Fei Wu, Cuijuan Gai, Jingzhe Yuan, Wenjun Chang, Haofu Dai, Xiachang Wang

“…Overall, our research results have enriched the library of secondary metabolites from soft corals, providing more molecular entities for subsequent research and development of related compounds.…”
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