Genetically Engineered Bacterial Ghosts as Vaccine Candidates Against <i>Klebsiella pneumoniae</i> Infection by Svetlana V. Dentovskaya, Anastasia S. Vagaiskaya, Alexandra S. Trunyakova, Alena S. Kartseva, Tatiana A. Ivashchenko, Vladimir N. Gerasimov, Mikhail E. Platonov, Victoria V. Firstova, Andrey P. Anisimov

“…<b>Results:</b> In the current study, we showed that co-expression of the holin and endolysin genes from the L-413C phage elicited more rapid and efficient <i>K. pneumoniae</i> lysis than lysis mediated by only single gene <i>E</i> or the low functioning holin–endolysin system of λ phage. …”
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Altered Metabolism in Knockdown Lines of Two HXXXD/BAHD Acyltransferases During Wound Healing in Potato Tubers by Jessica L. Sinka, Indira Queralta-Castillo, Lorena S. Yeung, Isabel Molina, Sangeeta Dhaubhadel, Mark A. Bernards

“…HXXXD/BAHD acyltransferases occupy a unique place in suberization, as they function to crosslink phenolic and aliphatic monomers during suberin assembly. …”
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The probability to initiate X chromosome inactivation is determined by the X to autosomal ratio and X chromosome specific allelic properties. by Kim Monkhorst, Bas de Hoon, Iris Jonkers, Eskeatnaf Mulugeta Achame, Wouter Monkhorst, Jos Hoogerbrugge, Eveline Rentmeester, Hans V Westerhoff, Frank Grosveld, J Anton Grootegoed, Joost Gribnau

“…<h4>Methodology/principal findings</h4>To obtain more insight in the role of the XratioA ratio in initiation of XCI, we generated triploid mouse ES cells by fusion of haploid round spermatids with diploid female and male ES cells. …”
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Clinical and cost-effectiveness of non-medical prescribing: A systematic review of randomised controlled trials. by Timothy Noblet, John Marriott, Emma Graham-Clarke, Debra Shirley, Alison Rushton

“…An associated cost analysis showed NMP to be more expensive than TAU (regression coefficient p = 0.0000), however experimental groups generated increased QALYs compared to TAU.…”
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Unveiling Surface Roughness Trends and Mechanical Properties in Friction Stir Welded Similar Alloys Joints Using Adaptive Thresholding and Grayscale Histogram Analysis by Haider Khazal, Azzeddine Belaziz, Raheem Al-Sabur, Hassanein I. Khalaf, Zerrouki Abdelwahab

“…This study attempts to provide a deeper understanding of the nature of the surface formation and roughness of aluminum joints during FSW processes. In order to form more efficient joints, the frictional temperature generated was monitored until reaching 450 °C, where the transverse movement of the tool and the joint welding began. …”
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Clarifying the Actual Situation of Old-Old Adults with Unknown Health Conditions and Those Indifferent to Health Using the National Health Insurance Database (KDB) System by Mio Kitamura, Takaharu Goto, Tetsuo Ichikawa, Yasuhiko Shirayama

“…In the comparison of health assessments between UHCs and KUs, “body weight loss” and “cognitive function” were more prevalent among KUs, and “smoking” and “social participation” were more prevalent among UHCs. …”
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Social Networks Link Prediction Based on Incremental Learning by Jian SHU, Zhichen CHEN

“…An incremental update strategy is designed for each network layer to generate updated random walk sequences, employing a temporal random walk approach. …”
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PA6 Stromal Cell Co-Culture Enhances SH-SY5Y and VSC4.1 Neuroblastoma Differentiation to Mature Phenotypes. by Ross Ferguson, Vasanta Subramanian

“…Since neuroblastoma cells proliferate and generally do not express markers of mature or functional neurons, we exploited a co-culture system with the stromal cell line PA6 to better induce differentiation to a more physiologically relevant status. …”
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A novel lightweight hybrid cryptographic framework for secure smart card operations by Kranthi Kumar Singamaneni

“…In this article, we propose a novel hybrid crypto standard to enhance the security and privacy of the transactions using smart cards, to achieve this we integrate Elliptic Curve Cryptography Curve25519 to generate secure keys, SPECK block cipher for lightweight encipherment with a powerful hash function for message authentication and integrity checks called PHOTON. …”
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HnRNPM modulates alternative splicing in germ cells by recruiting PTBP1 by Peng Lv, Wenchao Xu, Sheng Xin, Yuanxuan Deng, Bin Yang, Dengjianyi Xu, Jian Bai, Deilin Ma, Tao Wang, Jihong Liu, Xiaming Liu

“…Conditional hnRNPM knockout mice were generated to observe the development of testes and germ cells in male mice. …”
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Software diversity evaluation method based on the properties of ROP/JOP gadgets by Yuning CHI, Yunfei GUO, Yawen WANG, Hongchao HU

“…In order to reduce the risk of rapid spread of homogeneous attacks in network systems, and enhance network and software security, software diversification technologies are applied widely nowadays.Software diversification aims to generate functionally equivalent but internally changed program variants, thereby alter a single operating environment and mitigating homogenization attacks.The existing diversified technical evaluation index ROP gadgets survival rate is difficult to directly reflect the safety impact and the evaluation method is single.In order to evaluate the effectiveness of the diversification method more comprehensively and effectively, a software diversification evaluation method based on the properties of ROP/JOP gadgets is proposed, by analyzing common code reuse attacks, and turns abstract quantification into concrete indicators evaluates the security gain and effect of diversified methods from three aspects of space, time and quality.The method first discusses how diversification techniques affect ROP/JOP attacks according to the three properties of gadgets similarity, damage degree and availability.Nine kinds of diversification methods, such as instruction replacement, NOP insertion, and control flow flattening, are used to diversify the GNU coreutils assembly to generate diversification assembly.Experiments based on the property of gadgets are carried out on the diverse assemblies, and the effectiveness of different diversification methods and the impact on attacks are evaluated according to the experimental results.The experimental results show that this method can accurately evaluate the security gain of software diversification methods, the diversification technology will lead to the increase of the attack chain space required by the ROP/JOP attack, the longer time to construct the attack chain and the lower the attack success rate.The effects of different diversification methods are different, it has a guiding role for the follow-up research on diversified technologies with higher safety gains.…”
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Surfactants Adsorption onto Algerian Rock Reservoir for Enhanced Oil Recovery Applications: Prediction and Optimization Using Design of Experiments, Artificial Neural Networks, and... by Kahina Imene Benramdane, Mohamed El Moundhir Hadji, Mohamed Khodja, Nadjib Drouiche, Bruno Grassl, Seif El Islam Lebouachera

“…While DOE showed a slight advantage in relative error (9.10 × 10⁻⁵% vs. 1.88 × 10⁻⁴% for ANN), ANN proved more effective overall. Three optimization approaches—ANN-GA, DOE-GA, and DOE-DF (desirability function)—were compared, all converging to the same optimal conditions (SDS at 200 ppm and 25 °C). …”
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Detection of water surface targets based on improved Deformable DETR by Pengjiu WANG, Junbin Gong, Wei LUO, Xiao HUANG, Junjie GUO

“…During training, the model's loss function exhibited faster and more stable convergence. …”
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RMixDA: A Random Compound Data Augmentation Operation Framework for Neural Machine Translation by Huijun Wang, Xiaojing Du, Xinkun Hao

“…We further incorporate contrastive learning, identifying augmented data as positive or negative samples to evaluate similarity more effectively. Additionally, a novel evaluation method for augmented data quality is introduced, which is regularized by the NMT model&#x2019;s loss function to improve the positive correlation between augmented data quality and model training. …”
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Innovative Strategies For Social-Economic Development Financial Strategies In The Development Country by Chukwu Anthony Ogochukwu, Karina Kasztelnik

“…The research study highlighted the need for both the government and financing institutions to support small businesses to function effectively to remain relevant, continue to generate more employment, improve the living standard of the owners of small business, and ultimately impact development country at large. …”
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Drugs of abuse drive neurotransmitter plasticity that alters behavior: implications for mental health by Marta Pratelli, Marta Pratelli, Nicholas C. Spitzer, Nicholas C. Spitzer

“…Changes in the transmitter neurons express can generate changes in animal behavior. The ability of neurons to express multiple transmitters and/or switch them in response to environmental stimuli likely evolved to provide flexibility and complexity to neuronal circuit function in an ever-changing environment. …”
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Combined metabolomic and transcriptomic analysis reveals the key genes for triterpenoid biosynthesis in Cyclocarya paliurus by Duo Chen, Xupeng Chen, Xuehai Zheng, Jinmao Zhu, Ting Xue

“…Triterpenoids can improve the bioactive function of C. paliurus health tea and also improve the efficacy of health care tea. …”
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Effects of Acute Time-Restricted Eating on Inflammation in Individuals With Psoriasis: Protocol for a Case-Control, Prospective Study by Sinibaldo Romero Arocha, Kim Han, Rebecca D Huffstutler, Geethika P Thota, Natalie A Macheret, Amber B Courville, Robert J Brychta, Kong Y Chen, Stephanie T Chung, Laura C Coates, Alexander J Clarke, Michael N Sack

“…Recent studies suggest TRE may improve immune function in individuals with metabolic syndrome and cardiovascular risk factors. …”
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PIPELINE INSPECTION GAUGE MAGNETIC SENSOR CALIBRATION USING TIME-HARMONIC ELECTROMAGNETIC FIELD by R.E. Vavilov, V.A. Goldberg

“…The choice of a harmonic function for the calibration magnetic field generation is also due to the convenience of the hardware implementation of the procedure for generating the input signal of a measure of magnetic quantity. …”

THE FIGHT AGAINST FRAUD IN THE EUROPEAN UNION by Mihaela Iuliana DUMITRU, Diana Elena BRINZA

“…The totality of these actions is more and more extensive, given that the access to the Community financial support is currently facilitated, as a result of the particular conditions generated by the pandemic. …”
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