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921
Site specific mutation of the Zic2 locus by microinjection of TALEN mRNA in mouse CD1, C3H and C57BL/6J oocytes.
Published 2013-01-01“…This technology enables allelic series of mutations to be generated quickly and efficiently in diverse genetic backgrounds and will be a valuable approach to rapidly create mutations in mice already bearing one or more mutant alleles at other genetic loci without the need for lengthy backcrossing.…”
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922
Aerodynamic Optimization Method for Propeller Airfoil Based on DBO-BP and NSWOA
Published 2024-11-01“…The NACA4412 airfoil is selected as the research subject, optimizing the original airfoil at three angles of attack (2°, 5° and 10°). The CST (Class Function/Shape Function Transformation) airfoil parametrization method is used to parameterize the original airfoil, and Latin hypercube sampling is employed to perturb the original airfoil within a certain range to generate a sample space. …”
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923
Systems genetic analysis of osteoblast-lineage cells.
Published 2012-01-01“…In conclusion, we have identified a physiologically relevant gene network and used it to discover novel genes and regulatory mechanisms involved in the function of osteoblast-lineage cells. Our results highlight the power of harnessing natural genetic variation to generate co-expression networks that can be used to gain insight into the function of specific cell-types.…”
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924
ROLE OF FLUID ON THE CONTACT DEFORMATION RESPONSE OF BIOLOGICAL TISSUE
Published 2020-06-01“…All natural biological materials contain fluid and function in a fluidic environment, which plays a critical role in responding to loading events as well as tissue nutrition. …”
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925
Neural mechanisms in resolving prior and likelihood uncertainty in scene recognition
Published 2025-06-01“…By combining these AI-generated images with the task, we conducted a functional magnetic resonance imaging (fMRI) experiment enabling systematic control of both likelihood and prior information. …”
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926
Traversability Analysis and Path Planning for Autonomous Wheeled Vehicles on Rigid Terrains
Published 2024-08-01“…Afterward, the TV-Hybrid A* algorithm is proposed by redefining the path cost functions of the Hybrid A* algorithm through the simulation data and neural network method to generate a more cost-effective path. …”
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927
Autonomous Robotic Path Planning Based on the Gaussian Mixture Model in Complex Manufacturing Environment
Published 2024-01-01“…Secondly, the initial path is determined using the path generation configuration library, and a segmented path fitness function is introduced to evaluate the quality of the path quantitatively. …”
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928
Multi-scale adversarial diffusion network for image super-resolution
Published 2025-04-01“…On the other hand, although the existing methods can generate diverse and detailed samples, they tend to perform unsatisfactorily on fidelity metrics such as the peak signal-to-noise ratio (PSNR). …”
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929
Optimizing Dendritic Cell-Based Immunotherapy: Tackling the Complexity of Different Arms of the Immune System
Published 2012-01-01“…A better insight in DC immunobiology and function has stimulated many new ideas regarding the potential ways forward to improve DC therapy in a more fundamental way. …”
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930
Combining 3‐D Probabilistic Kinematic Modeling With Thermal Resetting Measurements: An Approach to Reduce Uncertainty in Exhumation Histories
Published 2025-03-01“…The resulting, more robust model can then be used to re‐interpret the thermal resetting data. …”
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931
Assessing the Influence of Selected Permeabilization Methods on Lymphocyte Single-Cell Multi-Omics
Published 2025-02-01“…(1) Background: Single-cell multi-omics is a powerful method for the dissection and detection of complicated immunologic functions and synapses. However, most currently available technologies merge datasets of different omics from separate portions of the same sample to generate combined multi-omics. …”
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932
Research on cardiac image segmentation algorithm based on improved level set modeling
Published 2025-07-01“…The model demonstrates the ability to quickly generate curves and accurately represent the contours of cardiac images. …”
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933
The “What” of Athletes’ Goal Pursuit and Its Relationships to Goal-Related Processes and Well- and Ill-Being
Published 2025-05-01“…The results showed that intrinsic goals, assessed in an open-ended format, were more heterogeneous in terms of content, and more common among athletes than extrinsic goals. …”
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934
Constructing a web recommender system using web usage mining and user’s profiles
Published 2014-12-01“…Date is of importance since it is more possible for users to request new pages more than old ones and old pages are less probable to be viewed, as users mostly look for new information. …”
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935
Deformation anisotropy and lamellar α re-orientation of TC17 alloy under the different slip modes of HCP structure
Published 2024-11-01“…Therein, the variation of the rotation factor with tilt angle conforms to the quadratic function, reaching a maximum value around 45°. When the rotation factor is small, the ratio of (01–11) [1–210] slip system with small Burgers vector at the phase boundary is large, the rotation tendency is poor, and the intragranular dislocation slip replaces the grain rotation as the strain accommodation mechanism, the lamella is more prone to globularization. …”
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936
A Comparative Study of Storage Batteries for Electrical Energy Produced by Photovoltaic Panels
Published 2025-08-01“…The findings of this study may be applicable to the storage of battery-generated electrical energy used for supplying electrical motors in electric cars.…”
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937
A modern approach to identifying and characterizing child asthma and wheeze phenotypes based on clinical data.
Published 2019-01-01“…Latent class analysis using current and historical clinical symptom data generated asthma and wheeze phenotypes. Characterization was then performed with regression analyses using diagnostic data: lung function and immunological biomarkers, parent-reported medication use and risk-factors. …”
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938
MAP kinase phosphatase-2 plays a critical role in response to infection by Leishmania mexicana.
Published 2010-11-01“…In this study we generated a novel dual specific phosphatase 4 (DUSP4) deletion mouse using a targeted deletion strategy in order to examine the role of MAP kinase phosphatase-2 (MKP-2) in immune responses. …”
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939
Effect of Calcium on the Characteristics of Action Potential Under Different Electrical Stimuli
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940
EVALUATING DEGREE OF ACTIVE POWER LOSSES REDUCTION IN THE ELECTRIC POWER LINES WITH REACTIVE POWER COMPENSATION
Published 2016-02-01“…They perform mathematical analysis of the obtained functional relations and study the function by means of derivatives. …”
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