Metagenomic and physicochemical profiling reveal microbial functions in pit mud for Jiang-Nong Jianxiang Baijiu fermentation by Lianbin Cao, Hongmei Sun, Ziyi Xu, Xiaoxiao Xu, Guangchuan Shi, Jianqiang Zhang, Changli Liang, Tongbiao Li, Chaoying Liu, Mingcheng Wang, Shilin Tian, Enzhong Li

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PhyloFunc: phylogeny-informed functional distance as a new ecological metric for metaproteomic data analysis by Luman Wang, Caitlin M. A. Simopoulos, Joeselle M. Serrana, Zhibin Ning, Yutong Li, Boyan Sun, Jinhui Yuan, Daniel Figeys, Leyuan Li

“…A more informative functional distance metric that incorporates evolutionary relatedness is needed to better understand microbiome functional dissimilarities. …”
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Precipitation–fire functional interactions control biomass stocks and carbon exchanges across the world's largest savanna by M. Williams, M. Williams, D. T. Milodowski, D. T. Milodowski, T. L. Smallman, T. L. Smallman, K. G. Dexter, G. C. Hegerl, I. M. McNicol, M. O'Sullivan, C. M. Roesch, C. M. Ryan, C. M. Ryan, S. Sitch, A. Valade

“…Compared to this analysis, LSMs showed marked differences in spatial distributions and magnitudes of C stocks and fire emissions. The current generation of LSMs represents savanna as a single plant functional type, missing important spatial functional variations identified here. …”
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Space Debris Sky Survey Observation Strategy Based on HEALPix and Greedy Algorithm by Shuqi Liu, Shaoming Hu, Junju Du, Hai Cao, Bo Zhang, Yuchen Jiang, Shuai Feng

“…The characteristics of the telescope and dynamic changes in the movement and position of space debris are considered in this strategy. An objective function was designed based on these factors. Using the pixelated sphere method to finely divide the celestial area, applying the summation filtering method, and using a greedy algorithm, the benefit of the objective function can be maximized, thus generating the optimal sky survey observation strategy. …”
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Effects of pneumatic tube systems on viscoelastic coagulation tests in septic patients and healthy individuals: protocol of the randomized controlled VETaPT-trial by Martin Mirus, Erik Buehrer, Lars Heubner, Christian Schnabel, Thea Koch, Peter Markus Spieth

“…However, the effect of PTS transport on VET results remains unclear, especially with newer VET technologies and in critically ill patients, who may be more vulnerable to acceleration forces.ObjectiveThe VETaPT (Viscoelastic Testing after Pneumatic Tube Transport) trial investigates whether PTS transport influences results of three next generation VET and platelet function testing in healthy volunteers and critically ill septic patients. …”
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A fusion analytic framework for investigating functional brain connectivity differences using resting-state fMRI by Yeseul Jeon, Jeong-Jae Kim, SuMin Yu, Junggu Choi, Sanghoon Han, Sanghoon Han

“…The framework involves three steps: first, constructing ROI-based Functional Connectivity Networks (FCNs) to manage resting-state fMRI data; second, employing a Self-Attention Deep Learning Model (Self-Attn) for binary classification to generate attention distributions encoding group-level differences; and third, utilizing a Latent Space Item-Response Model (LSIRM) to extract group-representative ROI features, visualized on group summary FCNs.ResultsWe applied our framework to analyze four types of cognitive impairments, demonstrating their effectiveness in identifying significant ROIs that contribute to the differences between the two disease groups. …”
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Enhancing bioactive profiles of elderberry juice through yeast fermentation: a pathway to low-sugar functional beverages by Amir Shazad, Ali Zein Alabiden Tlais, Davide Gottardi, Pasquale Filannino, Francesca Patrignani, Rosalba Lanciotti, Marco Gobbetti, Raffaella Di Cagno

“…In response to the growing need for functional beverages, this study aimed to harness yeast metabolism to optimize elderberry juice fermentation, targeting sugar reduction and enrichment of bioactive compounds with enhanced functional properties. …”
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AGREE: an upper limb motorized exoskeleton for restoring arm functions: a single-blinded randomized controlled trial by Marta Gandolla, Beatrice Luciani, Valeria Longatelli, Peppino Tropea, Agnese Seregni, Massimo Corbo, Francesco Braghin, Alessandra Pedrocchi

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Novel role of microphthalmia-associated transcription factor in modulating the differentiation and immunosuppressive functions of myeloid-derived suppressor cells by Yoon Kyung Jeon, Aram Lee, Haesun Park, Soyoung Lim, Jihyun Lim, Jaemoon Koh, Young Yang, Myeong-Sok Lee, Jong-Seok Lim

“…Furthermore, IHC staining of human tumor tissues revealed that MITF+ MO-MDSCs are more frequently observed in tumor tissues than in tumor-free draining lymph nodes obtained from patients with cancer.Conclusions Our results indicate that MITF regulates the differentiation and function of MDSCs and can be a novel therapeutic target for modulating MDSC activity in immunosuppressive TMEs.…”
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CTLA4Ig Improves Murine iTreg Induction via TGFβ and Suppressor Function In Vitro by Nina Pilat, Benedikt Mahr, Martina Gattringer, Ulrike Baranyi, Thomas Wekerle

“…However, since the CD28 pathway is more complex than initially thought, the question arose whether blocking CD80/86 would inadvertently impact immunological tolerance by interfering with Treg generation and function. …”
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The Unpaved Road of Non-Coding RNA Structure–Function Relationships: Current Knowledge, Available Methodologies, and Future Trends by Ana Lúcia Leitão, Francisco J. Enguita

“…Non-coding RNA action is predominantly driven by sequence and structural motifs that interact with specific functional partners. Despite the exponential growth in primary RNA sequence data facilitated by next-generation sequencing studies, the availability of tridimensional RNA data is comparatively more limited. …”
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Role of AI and 3D quantitative computed tomography in obstructive airway diseases in correlation with pulmonary function tests by Amira Abdalla saad, Ahmed M. Osman, Hossam M. Abdelhamid, Mai Mohammad Sedik

“…Results A direct relation was discovered between wall thickness (WT), wall area (WA), and luminal area (LA) of the 3rd-generation bronchus of the right lower lung lobe and forced vital capacity (FVC), while no strong relation was found in the 4th and 5th generations. …”
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Adaptive genetics reveals constraints on protein structure/function by evolving E. coli under constant nutrient limitation by Katja Schwartz, Margie Kinnersley, Charles Ross Lindsey, Gavin Sherlock, Frank Rosenzweig

“…Whole-genome whole-population sequencing makes it possible to identify mutations arising in such populations, to use them to discern functional modules where adaptation occurs, and then map gene structure–function relationships. …”
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A novel spectral transformation technique based on special functions for improved chest X-ray image classification. by Abeer Aljohani

“…The image pre processing and spectral moments generation is performed in Matlab and the implementation of the classifiers is performed with python. …”
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Telomerase activity in T-cells as a functional test for pathogenicity assessment of novel genetic variants in telomere biology disorders by Olivia Carlund, Anna Norberg, Pia Osterman, Ida Andersson, Alva Eriksson, Sofie Degerman, Magnus Hultdin

“…We have developed a functional TA assay in patient-derived T-cells based on the Telomeric Repeat Amplification Protocol (TRAP) combined with qPCR. …”
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Novel Flavin Mononucleotide-Functionalized Cerium Fluoride Nanoparticles for Selective Enhanced X-Ray-Induced Photodynamic Therapy by Anastasia I. Kornienko, Maria A. Teplonogova, Marina P. Shevelyova, Matvei A. Popkov, Anton L. Popov, Vladimir E. Ivanov, Nelli R. Popova

“…This activity results in the generation of reactive oxygen species, which is associated with the scintillation properties of cerium and the transfer of electrons to FMN. …”
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FEATURES OF WRITTEN LANGUAGE COMMUNICATION BY MEANS OF THE UKRAINIAN LANGUAGE (on the example of official-business, epistolary and conversational-functional styles) by Catherine S. Bondarchuk, Olha A. Chumachenko

“…The article analyzes the main types of oral and written communication on the material of different functional styles of the Ukrainian language. The research methodology consists of both the main methods of functional stylistics and its partial and concrete-practical methods, namely: functional, complex, semantic, comparative methods, multifaceted analysis and the method of direct observation. …”
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Influence of environmental exposures on T follicular helper cell function and implications on immunity: a comparison of Bangladeshi and American children by Dana M. Van Fossen, Hyunjae Cho, Lisa E. Wagar, Jennie Z. Ma, Julie Parsonnet, Rashidul Haque, Mark M. Davis, William A. Petri

“…The generation of an effective memory response to infection is vital to prevent subsequent reinfections. …”
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Multimodal Fusion Framework for Urban functional zone change detection using Remote Sensing and Social Sensing Data by B. Fang, B. Fang, B. Fang, B. Fang, X. Chen, X. Chen, X. Chen, X. Chen, H. Chen, H. Chen, Z. Xiang, Z. Xiang, B. Hu, B. Hu, Z. Hu, Z. Hu, Z. Hu, Z. Hu, W. Tu, W. Tu, W. Tu, W. Tu

“…For the RS-branch, RS imagery provides detailed spatial information about urban transformations; for the MP-branch, MP data as a typical social sensing data captures temporal patterns in human mobility, offering insights into functional shifts in urban spaces. By fusing these two complementary modalities, our approach allows for a more nuanced detection of urban functional zone changes. …”
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Predicting the treatment outcomes of major depressive disorder interventions with baseline resting-state functional connectivity: a meta-analysis by Yanyao Zhou, Na Dong, Letian Lei, Dorita H. F. Chang, Charlene L. M. Lam

“…Nodes were categorized according to the type of brain networks they belong to, and pooled coefficients were generated for rsFC connections reported by more than three studies. …”
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