Chemotranscriptomic analysis of 7-hydroxymatairesinol-related effects on MCF7 human breast tumor cells by I. Yu. Torshin, A. N. Rubashkina, O. A. Gromova

“…As a result, a panel of genes with altered expression is generated, which are analyzed by the functional linkage method using the international nomenclature of Gene Ontology (GO) linked to biological roles of genes/proteins.Results. …”
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Accelerating crystal structure search through active learning with neural networks for rapid relaxations by Stefaan S. P. Hessmann, Kristof T. Schütt, Niklas W. A. Gebauer, Michael Gastegger, Tamio Oguchi, Tomoki Yamashita

“…Using this approach, we are able to effectively identify the most promising candidates for further evaluation using density functional theory (DFT). Our method not only reliably reduces computational costs by up to two orders of magnitude across the benchmark systems Si16, Na8Cl8, Ga8As8 and Al4O6 but also excels in finding the most stable minimum for the unseen, more complex systems Si46 and Al16O24. …”
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Application of the New Mapping Method to Complex Three Coupled Maccari’s System Possessing M-Fractional Derivative by Jan Martinovic, Aziz Ur Rehman, Muhammad Bilal Riaz

“…Analytical solutions are subsequently generated through the application of the new mapping method. …”
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Extracting road maps from high-resolution satellite imagery using refined DSE-LinkNet by Prativa Das, Satish Chand

“…The current methodologies generate the disconnected road segments, cause boundary loss, and also they are incapable of handling the imbalanced class distribution problems. …”
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Enzymatic twists evolved stereo-divergent alkaloids in the Solanaceae family by Adam Jozwiak, Michaela Almaria, Jianghua Cai, Sayantan Panda, Hadas Price, Ron Vunsh, Margarita Pliner, Sagit Meir, Ilana Rogachev, Asaph Aharoni

“…Ancestral GAME8 likely favored 25R, with gene duplications giving rise to 25S-producing enzymes in more recent Solanum species. In S. nigrum and S. dulcamara, multiple GAME8 copies generate mixed isomeric profiles. …”
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The role of flotillins in regulating aβ production, investigated using flotillin 1-/-, flotillin 2-/- double knockout mice. by Vassilis Bitsikas, Kirsi Riento, Jonathan D Howe, Nicholas P Barry, Benjamin J Nichols

“…In this study we set out to obtain in vivo confirmation of a link between flotillins and cleavage of APP to release amyloidogenic Aβ peptide, and to generate tools that would allow us to ask whether flotillins are functionally redundant. …”
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In Vitro Anthelmintic Activities of Khaya anthotheca and Faidherbia albida Extracts Used in Chad by Traditional Healers for the Treatment of Helminthiasis and In Silico Study of Ph... by Baigomen Christalin, Masoud Besati, Noumedem Anangmo Christelle Nadia, Mahdi Yaghoobi, Yamssi Cédric, Claire Ciancia, Mounvera Abdel Azizi, Gamago Nkadeu Guy-Armand, Vincent Khan Payne, Haibo Hu

“…Docking studies were carried out using the Schrodinger Maestro software’s Glide module. The score function in the software was used to rank and group distinct possible adduct structures generated by molecular docking. …”
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Glucagon-like peptide-1 receptor agonists in neurodegenerative diseases: Promises and challenges by Zhi Dong Zhou, Lingxiao Yi, Karolina Popławska-Domaszewicz, Kallol Ray Chaudhuri, Joseph Jankovic, Eng King Tan

“…Experimental studies have shown that GRA have protective effects to modulate neuroinflammation, oxidative stress, mitochondrial and autophagic functions, and protein misfolding. Hence the compounds have generated enormous interest as novel therapeutic agents against NDs. …”
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Testing an inverse modeling approach with gradient boosting regression for stroke volume estimation using patient thermodilution data by Vasiliki (Vicky) Bikia, Dionysios Adamopoulos, Dionysios Adamopoulos, Dionysios Adamopoulos, Marco Roffi, Marco Roffi, Georgios Rovas, Stéphane Noble, Stéphane Noble, François Mach, François Mach, Nikolaos Stergiopulos

“…Stroke volume (SV) is a major indicator of cardiovascular function, providing essential information about heart performance and blood flow adequacy. …”
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Autonomous Robotic Path Planning Based on the Gaussian Mixture Model in Complex Manufacturing Environment by Rui Sun, Yuanmin Wang, Wenzheng Zhao, Yinhua Liu

“…Secondly, the initial path is determined using the path generation configuration library, and a segmented path fitness function is introduced to evaluate the quality of the path quantitatively. …”
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A method for benchmarking genetic screens reveals a predominant mitochondrial bias by Mahfuzur Rahman, Maximilian Billmann, Michael Costanzo, Michael Aregger, Amy H Y Tong, Katherine Chan, Henry N Ward, Kevin R Brown, Brenda J Andrews, Charles Boone, Jason Moffat, Chad L Myers

“…Abstract We present FLEX (Functional evaluation of experimental perturbations), a pipeline that leverages several functional annotation resources to establish reference standards for benchmarking human genome‐wide CRISPR screen data and methods for analyzing them. …”
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Multi-scale adversarial diffusion network for image super-resolution by Yanli Shi, Xianhe Zhang, Yi Jia, Jinxing Zhao

“…On the other hand, although the existing methods can generate diverse and detailed samples, they tend to perform unsatisfactorily on fidelity metrics such as the peak signal-to-noise ratio (PSNR). …”
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Optimizing Dendritic Cell-Based Immunotherapy: Tackling the Complexity of Different Arms of the Immune System by Ilse Van Brussel, Zwi N. Berneman, Nathalie Cools

“…A better insight in DC immunobiology and function has stimulated many new ideas regarding the potential ways forward to improve DC therapy in a more fundamental way. …”
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Development of a Force Feedback Controller with a Speed Feedforward Compensator for a Cable-Driven Actuator by Juan Fang, Michael Haldimann, Bardia Amiryavari, Robert Riener

“…Accurate control of cable force is essential for achieving precise movement control, especially when the movement is generated by multiple CDAs. However, velocity-induced disturbances pose challenges to accurate force control during dynamic movements. …”
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The Effect of Hydrogen Peroxide on Biogas and Methane Produced from Batch Mesophilic Anaerobic Digestion of Spent Coffee Grounds by Siham Sayoud, Kerroum Derbal, Antonio Panico, Ludovico Pontoni, Massimiliano Fabbricino, Francesco Pirozzi, Abderrezzaq Benalia

“…This paper aims to explore both experimental and modeling anaerobic digestion (AD) processes as innovative methods for managing the substantial quantities of spent coffee grounds (SCG) generated in Algeria, transforming them into valuable renewable energy sources (biogas/methane). …”
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The AMD-associated genetic polymorphism CFH Y402H confers vulnerability to Hydroquinone-induced stress in iPSC-RPE cells by Angela Armento, Inga Sonntag, Ana-Cristina Almansa-Garcia, Merve Sen, Sylvia Bolz, Blanca Arango-Gonzalez, Ellen Kilger, Ruchi Sharma, Kapil Bharti, Rosario Fernandez-Godino, Berta de la Cerda, Simon J. Clark, Simon J. Clark, Simon J. Clark, Marius Ueffing

“…There has been, and continues to be, much discussion around the functional consequences of this Y402H polymorphism, whether the soluble FH protein confers its risk association, or if the cells expressing the protein themselves are affected by the genetic alteration. …”
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Establishing a 3D Spheroid Model of Cholinergic Neurons from SH-SY5Y Cells for Neurotoxicity Assessment by Felipe Franco-Campos, Mónica Fernández-Franzón, Yelko Rodríguez-Carrasco, María-José Ruiz

“…SH-SY5Y cells, an immortalized human neuroblastoma cell line, provide a more accessible alternative for studying neuronal processes and neurotoxicity. …”
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A DEM super resolution reconstruction method based on normalizing flow by Jie Yu, Yangtenglong Li, Xuan Bai, Ronghao Yang, Mengxue Cui, Haohao Wu, Zheng Li, Fangzheng Su, Ze Li, Taohuai Liang, Hongliang Yan

“…The negative log-likelihood function and pixel loss function are used to accelerate the optimization to generate high-resolution DEM images that are closer to the natural terrain. …”
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Clinical Versatility of the Facility-Equator Implant System as Mandibular Overdenture Retainers by Anna Paula da Rosa Possebon, Alessandra Julie Schuster, Amália Machado Bielemann, Ana Paula Pinto Martins, Samille Biasi Miranda, Otacílio Luiz Chagas-Júnior, Luciana de Rezende Pinto, Fernanda Faot

“…The case with 4 implants and progressive loading showed a slight worsening of masticatory function at 1 year, in addition to a more pronounced MBL compared to other cases, but with improvements in satisfaction and oral health-related quality of life. …”
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Comparing a Guideline-Based Mobile Health Intervention Versus Usual Care for High-Risk Adolescents With Asthma: Protocol of a Randomized Controlled Trial by Tamara T Perry, Jessica H Turner, Ariel Berlinski, Larry A Simmons, Rita H Brown, Kaymon Neal, Sarah A Marshall, Xing He, Simon Chung, Andrew Brown, Horace J Spencer 3rd, Jiang Bian

“…The study has 3 aims: (1) examine the effectiveness of PEAKmAAP in reducing asthma morbidity, as measured by the Asthma Control Test (ACT) score, health care use, medication use, and lung function; (2) examine the effectiveness of PEAKmAAP in asthma self-efficacy and medication adherence; and (3) examine the impact of sharing PEAKmAAP-generated data with the primary care provider (PCP) for a subset of enrolled subjects. …”
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