Billion‐Scale Expansion of Functional hiPSC‐Derived Cardiomyocytes in Bioreactors Through Oxygen Control and Continuous Wnt Activation by Pedro Vicente, Lara R. Inocêncio, Asier Ullate‐Agote, Ana F. Louro, João Jacinto, Beatriz Gamelas, Olalla Iglesias‐García, Patxi San Martin‐Uriz, Paula Aguirre‐Ruiz, Gonzalo R. Ríos‐Muñoz, María Eugenia Fernández‐Santos, Alain vanMil, Joost P. G. Sluijter, Felipe Prósper, Manuel M Mazo Vega, Paula M. Alves, Margarida Serra

Get full text

Adaptation and validation of the Washington group/unicef child functioning module in a nationally representative sample of Canadian children and youth by Emma Nolan, Katherine Cost, Ryan Miller, Li Wang, Chen Yun-Ju, Jordan Edwards, Eric Duku, Stelios Georgiades, Peter Szatmari, Harriet MacMillian, Charlotte Waddell, Katholiki Georgiades

“…Findings highlight the value of a dimensional approach to functional difficulties, offering a more comprehensive understanding of population-level variations in functioning. …”
Get full text

Gut microbiota and kidney function in autosomal dominant polycystic kidney disease participants in Cameroon: a cross-sectional study by Inès Obolo Nwaga, Victorine Bandolo Nzana, Rhoda Nsen Bughe, Isaac Dah, Cheboh Cho-Fon, Maimouna Mahamat, Emmanuelle Ndjong, Aristide Nono, Jean Claude Mballa, Fon Abongwa Acho, Vicky Ama Moor, Wilfred Fon Mbacham, François Folefack Kaze

Get full text

HLA antibodies and their value during renal transplantation by M. Sh. Khubutia, N. V. Borovkova, R. V. Storozhev, N. V. Doronina, M. V. Storozheva, A. S. Pertsev, A. V. Pinchuk

Get full text

Randomness-free detection of non-projective measurements: qubits & beyond by Sumit Rout, Some Sankar Bhattacharya, Paweł Horodecki

“…We provide numerical evidence for the robustness of this scheme under arbitrary depolarizing noise. For a more generic consideration (bipartite and tripartite scenario), we provide numerical evidence for a projective-simulable bound on the reward function for our task. …”
Get full text

Behavioral interventions to benefit cognition (Intervenciones cognitivas para beneficiar la cognición) by Jennifer L. Etnier, Chia-Hao Shih, Aaron Piepmeier

“…In addition, given the likelihood that multiple underlying mechanisms support cognitive function, research is currently focusing on how to combine lifestyle factors into multi-component interventions to generate greater and more meaningful effects. …”
Get full text

Effectiveness of Applying the Theory of Planned Behavior with Yoga Program on the Physical Activity and Mental Health of the Prefrailty Older Adults by Ya Ting Wu, Miao Yen Chen, Yung Cheng Huang, Chieh Yu Liu

“…Objectives: Grounded in the theory of planned behavior (TPB), this study evaluated the effectiveness of a yoga program intervention on the physical functioning and mental health in older adults. Materials and Methods: This was a quasi-experimental two-group, pre- and posttest, single-blind study. …”
Get full text

Emotion dysregulation and impulsivity as overlapping symptoms in adult Attention-Deficit/Hyperactivity Disorder and Borderline Personality Disorder: severity profiles and associati... by Eszter Kenézlői, Lívia Balogh, Szilvia Somogyi, Evelyn E. Lévay, Zsuzsa Halmai, Zsófia Nemoda, Zsolt S. Unoka, János M. Réthelyi

Get full text

Development of channel transmission loss function for WRF_HYDRO modeling of semi-arid regions: The case of wadi Faria, Palestine by Abdelhaleem Khader, Anan Jayyousi, Sameer Shadeed, Joel Arnault, Harald Kunstmann, Christian Chwala, Benjamin Fersch

“…Faria (320 km2), located in the northeastern part of the West Bank, Palestine, is a gauged catchment where rainfall and streamflow data are available for more than ten years. This study aims to assess the functionality of the WRF-Hydro to predict reliable streamflow hydro-graphs at the upper part of the catchment. …”
Get full text

Change of concentration of biochemical markers of dysfunction of endothelium at intake of inhibitors of tyrosinekinase of I and II generations at patients with a chronic myeloid le... by K. V. Naumova, I. L. Davydkin, E. G. Lomaia, T. Yu. Stepanova, T. P. Kuzmina, D. B. Zammoyeva

“…CML), the accepting inhibitors tyrosine of kinases (TKI) I and the II generations (TKI1 and TKI2 respectively), and development of arterial hypertension.Material and methods. …”
Get full text

Selective metabolic regulations by p53 mutant variants in pancreatic cancer by Sabrina Caporali, Alessio Butera, Alessia Ruzza, Carlotta Zampieri, Marina Bantula’, Sandra Scharsich, Anna-Katerina Ückert, Ivana Celardo, Ian U. Kouzel, Luigi Leanza, Andreas Gruber, Joan Montero, Angelo D’Alessandro, Thomas Brunner, Marcel Leist, Ivano Amelio

“…Abstract Background Approximately half of all human cancers harbour mutations in the p53 gene, leading to the generation of neomorphic p53 mutant proteins. These mutants can exert gain-of-function (GOF) effects, potentially promoting tumour progression. …”
Get full text

Analysing Interaction in Science Classrooms by Kristina Danielsson, Ewa Bergh Nestlog, Fredrik Jeppsson, Kok-Sing Tang

“…The analyses of the communicative approaches have the potential of elucidating discursive patterns and power relations at a general level, while the analyses based on SFG can provide more details about the power relations in terms of how the participants actually structure their utterances. …”
Get full text

Effects of ginger supplementation in individuals with mild to moderate joint pain I: ratings of pain, functional capacity, and markers of inflammation by Jacob Broeckel, Landry Estes, Megan Leonard, Broderick Dickerson, Drew E. Gonzalez, Martin Purpura, Ralf Jäger, Ryan Sowinski, Christopher J. Rasmussen, Richard B. Kreider

“…Participants were matched by age, sex, and body mass for double-blind and to ingest 125 mg/d of a placebo or ginger (GingerT3®, Specnova LLC, Tysons Corner, Virginia), standardized to contain 10% total gingerols and no more than 3% total shogaols) for 58 days. Data were analyzed using the general linear model (GLM) analysis of variance with repeated measures, mean changes from baseline with 95% confidence intervals, and chi-squared analysis.Results There was evidence that ginger supplementation: 1.) attenuated perceptions of muscle pain in the vastus medialis (Day 2: χ2 p = 0.087); 2.) reported less pain from sitting (Day 2: χ2 p = 0.02), while nocturnal pain (Day 32: χ2 p = 0.075, Day 58: (χ2 p = 0.097), weight bearing pain (Day 32: χ2 p = 0.058), physical functioning of performing heavy duties (Day 32: χ2 p = 0.100), and physical functioning of performing light duties (Day 2: χ2 p = 0.064) on WOMAC questions; 3.) experienced significant reductions in WOMAC overall ratings of pain, stiffness, physical function, and total score values, particularly in 48-hour follow-up measures; 4.) reported less pain during nighttime bed rest (Day 2: χ2 p = 0.065; Day 32: χ2 p = 0.032) and when going up and down stairs (Day 32: χ2 p = 0.097) from the LEQ; and, 5.) promoted significant differences over time and/or between groups in IL-β, IL-5, IL-6, IL-8, INF-γ, TNF-α, and high sensitivity C-reactive Protein at various points during the study.Conclusion Ginger supplementation promotes some favorable effects on exercise-induced perceptions of pain, functional capacity, and inflammatory markers in men and women who have mild to moderate muscle and joint pain.Registered clinical trial #ISRCTN74292348.…”
Get full text

Assessment of goiter prevalence, iodine status and thyroid functions in school-age children of rural Yusufeli district in eastern Turkey by Behzat Ozkan, Haşim Olgun, Naci Ceviz, Pinar Polat, Seyithan Taysi, Zerrin Orbak, Celalettin Koşan

“…However, it has recently been reported that there are regions in Turkey where iodine deficiency is more severe than previously known. The current study was aimed at ascertaining the goiter prevalence by thyroid volumes, iodine status and thyroid functions in school-age children living in an area which is suspected to have moderate or severe iodine deficiency. …”
Get full text

Response of organic matter pore development to functional groups in overmature marine shale: Insights from AFM-IR spectroscopy by Jianhua ZHAO, Keyu LIU, Shenghui ZHAO, Qinhong HU, Wei WU, Yang CHEN, Guoheng LIU, Junqian LI, Lingjie YU, Zuhui YOU, Ye WANG

“…Pyrobitumen-clay mineral composites generally exhibit superior pore development, likely attributable to clay mineral dehydration participating in hydrocarbon generation reactions that promote the removal of more functional groups. …”
Get full text

Functional and sensory properties of iron and folic acid fortified NABE-3 bean and silver fish composite instant flour by Geoffrey Ssepuuya, Sharon Hooper, Khadijah Nakyinsige, Eria Gyagenda Maseruka, Dianah Musabi, Peter Rukundo, Harriet Kebirungi, Lorraine Weatherspoon, Jose Jackson-Malete

“…Incorporation of silver fish into NABE bean flour generally leads to increased sensory acceptability and nutrient density but reduced functionality.…”
Get full text

Dynamics of Clinical Manifestations and Social Functioning in Schizophrenia: A Non-interventional Observational Study of Paliperidone Palmitat Dosage Forms by Aleksandr M. Reznik, Olga A. Karpenko, Elena A. Shumakova, Aleksandr V. Mudrak, Andrey V. Sokolov, Svetlana V. Nazimova, Alina M. Saifulina, Anton M. Eliseenko, Tatjana K. Matvievskaya, Angelina N. Khannanova, Vladimir I. Revenko, Dmitriy V. Scherbakov, Yuriy L. Martynyuk, Aleksandr L. Arbuzov, Oleg A. Yacenko, Polina N. Alekseeva, Aleksandr B. Berdalin, Larisa A. Burygina

“…Hallucinations proved more susceptible to therapy (p 0.001), while persistent delusions showed greater treatment resistance. …”
Get full text

Milkweed (Asclepias syriaca) invasion, forest-steppe fragment size and isolation jointly constrain arthropod communities and their functional traits by Róbert Gallé, Ágota Réka Szabó, Edina Török, Tamás Lakatos, Dávid Korányi, Attila Torma, Nikolett Gallé-Szpisjak, Péter Batáry

Get full text

Functional Approaches to Discover New Compounds via Enzymatic Modification: Predicted Data Mining Approach and Biotransformation-Guided Purification by Te-Sheng Chang

Get full text

Statistical Analysis of Novel Ensemble Recursive Radial Basis Function Neural Network Performance on Global Solar Irradiance Forecasting by Manoharan Madhiarasan, Mohamed Louzazni, Brahim Belmahdi

“…This paper proposes a novel global solar irradiance forecasting model based on the ensemble recursive radial basis function neural networks (ERRBFNNs). The various atmospheric inputs based on the built ensemble recursive radial basis function neural networks make the network more stable and robust to climatic uncertainty. …”
Get full text