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5601
Cell-Type-Specific Heat-Induced Changes in the Proteomes of Pollen Mother Cells and Microspores Provide New Insights into Tomato Pollen Production Under Elevated Temperature
Published 2025-03-01“…These HS-induced DAPs include proteases, antioxidant proteins, and proteins related to cell wall remodeling and the generation of pollen exine. Conclusions: HS induced more dynamic proteomic changes in meiotic PMCs compared to microspores, and the inter-varietal differences in the PMC proteomes align with the effects of HS on pollen productivity observed in the two varieties. …”
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5602
Development mechanism and practical significance of deep coalbed methane (coal rock gas) infiltration and displacement
Published 2025-07-01“…For 2 nm pores under reservoir and post-fracturing pressure conditions, strong hydrophilic (30° contact angle) and weakly hydrophilic (70°) pores generated capillary forces exceeding 40.1 MPa and 15.8 MPa, respectively, creating intense imbibition driving forces. …”
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5603
Sensing of Liver‐Derived Nicotinamide by Intestinal Group 2 Innate Lymphoid Cells Links Liver Cirrhosis and Ulcerative Colitis Susceptibility
Published 2024-10-01“…Mechanistically, the NAD+ salvage pathway regulates gut ILC2s in a cell‐intrinsic manner by supporting the generation of succinate, which fuels the electron transport chain to sustaining ILC2s function. …”
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5604
Low expression of CCKBR in the acinar cells is associated with insufficient starch hydrolysis in ruminants
Published 2024-12-01“…A better understanding of the physiological mechanisms that regulate digestion patterns in ruminants could lead to an increased use of starch concentrates. Here we show more robust pancreatic exocrine function in adult goats (AG) than in neonatal goats (NG) by combining scRNA-seq and proteomic analysis. …”
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5605
On Solution Set Associated with a Class of Multiple Objective Control Models
Published 2025-08-01“…To this end, we introduce a new notion of <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mrow><mo>(</mo><msub><mi>ϑ</mi><mn>0</mn></msub><mo>,</mo><msub><mi>ϑ</mi><mn>1</mn></msub><mo>)</mo></mrow><mo>−</mo><mrow><mo>(</mo><msub><mi>σ</mi><mn>0</mn></msub><mo>,</mo><msub><mi>σ</mi><mn>1</mn></msub><mo>)</mo></mrow><mo>−</mo><mi>t</mi><mi>y</mi><mi>p</mi><mi>e</mi><mo>−</mo><mi>I</mi></mrow></semantics></math></inline-formula> functionals determined by multiple integrals. To better emphasize the significance of the suggested <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mrow><mo>(</mo><msub><mi>ϑ</mi><mn>0</mn></msub><mo>,</mo><msub><mi>ϑ</mi><mn>1</mn></msub><mo>)</mo></mrow><mo>−</mo><mrow><mo>(</mo><msub><mi>σ</mi><mn>0</mn></msub><mo>,</mo><msub><mi>σ</mi><mn>1</mn></msub><mo>)</mo></mrow><mo>−</mo><mi>t</mi><mi>y</mi><mi>p</mi><mi>e</mi><mo>−</mo><mi>I</mi></mrow></semantics></math></inline-formula> functionals and how they add to previous studies, we mention that the <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mrow><mo>(</mo><msub><mi>ϑ</mi><mn>0</mn></msub><mo>,</mo><msub><mi>ϑ</mi><mn>1</mn></msub><mo>)</mo></mrow><mo>−</mo><mrow><mo>(</mo><msub><mi>σ</mi><mn>0</mn></msub><mo>,</mo><msub><mi>σ</mi><mn>1</mn></msub><mo>)</mo></mrow><mo>−</mo><mi>t</mi><mi>y</mi><mi>p</mi><mi>e</mi><mo>−</mo><mi>I</mi></mrow></semantics></math></inline-formula> and generalized <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mrow><mo>(</mo><msub><mi>ϑ</mi><mn>0</mn></msub><mo>,</mo><msub><mi>ϑ</mi><mn>1</mn></msub><mo>)</mo></mrow><mo>−</mo><mrow><mo>(</mo><msub><mi>σ</mi><mn>0</mn></msub><mo>,</mo><msub><mi>σ</mi><mn>1</mn></msub><mo>)</mo></mrow><mo>−</mo><mi>t</mi><mi>y</mi><mi>p</mi><mi>e</mi><mo>−</mo><mi>I</mi><mo>−</mo><mi>t</mi><mi>y</mi><mi>p</mi><mi>e</mi><mi>I</mi></mrow></semantics></math></inline-formula> assumptions associated with the involved multiple integral functionals cover broader and more general classes of problems, where the convexity of the functionals is not fulfilled or the functionals considered are not of simple integral type. …”
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5606
Membrane Technology in the Production of Immunobiological Preparations Produced by the Branch Office of the FSBE «48 Central Scientific Research Institute» of the Ministry of Defen...
Published 2023-07-01“…This type of equipment for the sterilization of nutrient mediums can be considered as an alternative to the processes of the thermal sterilization of liquids and provides their biological and technological full functionality. Experiments on the use of the ceramic-metal filters sterilizing the air given for aeration, showed the decrease in duration of preparatory operations on 20 h and increase in the general operational opportunities of the system.…”
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5607
Safety of creatine supplementation: analysis of the prevalence of reported side effects in clinical trials and adverse event reports
Published 2025-09-01“…Additionally, there was no significant multivariate difference among the 49 side effects evaluated (p = 0.340), no significant difference in the total frequency of side effects reported among participants (PLA 4.21%, Cr 4.60%, p = 0.828), and no significant differences in any of the other side effect evaluated that included markers of renal function and health. The percentage prevalence of side effects was small, with differences between groups generally within ± 0.5%. …”
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5608
Case Report: The intersection of psychiatry and medicine: diagnostic and ethical insights from case studies
Published 2025-04-01“…The article critically examines terms like medically unexplained symptoms and functional disorders, highlighting their limitations and potential for misuse. …”
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5609
Daily Mobility in Metropolitan Areas
Published 2024-06-01“…Such day-to-day activities are further shaped by more dynamic and perhaps more subtle influences such as the changing functions of the urban space, increasing socioeconomic fragmentation and segmentation and the inequitable provision of public transport across what is a topographically complex area. …”
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5610
Non-feature-specific elevated responses and feature-specific backward replay in human brain induced by visual sequence exposure
Published 2025-05-01“…Together, these findings demonstrate that visual sequence exposure induces twofold brain plasticity that may simultaneously serve for different functional purposes. The non-feature-specific elevated responses may facilitate general processing of upcoming stimuli, whereas the feature-specific backward replay may underpin passive learning of visual sequences.…”
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5611
PA6 Stromal Cell Co-Culture Enhances SH-SY5Y and VSC4.1 Neuroblastoma Differentiation to Mature Phenotypes.
Published 2016-01-01“…Since neuroblastoma cells proliferate and generally do not express markers of mature or functional neurons, we exploited a co-culture system with the stromal cell line PA6 to better induce differentiation to a more physiologically relevant status. …”
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5612
Bleeding disorder of unknown cause: an illustrated review on current practice, knowledge gaps, and future perspectives
Published 2024-11-01“…The mucocutaneous bleeding phenotype of individuals with BDUC is generally comparable to that of individuals with inherited bleeding disorders such as von Willebrand disease or platelet function disorders. …”
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5613
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5614
The plasma proteome reveals distinct signaling pathways associated with PR3-ANCA positive and MPO-ANCA positive vasculitis
Published 2025-06-01“…Shared proteins were enriched in general immune pathways, including IL-6 signaling. …”
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5615
Cacao Agroforestry in Mahakam Ulu: Transformation Strategy from Traditional to Good Agricultural Practices and Smart Agroforestry System
Published 2025-06-01“…The implementation of cacao SAF is anticipated to enhance cacao productivity, improve the welfare of local communities, and preserve the forest’s function as a crucial life support system for the Dayak Community in Mahakam Ulu (Mahulu) District. …”
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5616
Real-world validation of safe reinforcement learning, model predictive control and decision tree-based home energy management systems
Published 2024-12-01“…Recent advancements in machine learning based energy management approaches, specifically reinforcement learning with a safety layer (OptLayerPolicy) and a metaheuristic algorithm generating a decision tree control policy (TreeC), have shown promise. …”
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5617
SARS-CoV-2 antibody responses in children exhibit higher FcR engagement and avidity than in adults
Published 2025-08-01“…Adults’ SARS-CoV-2 antibody responses could be derived from high avidity pre-existing cross-reactive common cold coronavirus B cell responses, whilst children appear to generate a de novo SARS-CoV-2- specific Spike and Nucleocapsid IgG with robust Fc receptor (FcR) binding ability and high avidity at a higher proportion than adults, thus their responses are more targeted and functional for SARS-CoV-2.…”
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5618
Rheumatoid arthritis and psoriatic arthritis: is the disease impact different? A large matching study at diagnosis and after 1 year of treatment
Published 2025-03-01“…This difference still existed after 1 year of treatment (3.88 (95% CI 1.90 to 5.86)). PsA-EAC patients had more activity limitations after 1 year of treatment compared with RA-EAC patients (−0.30 (95% CI −0.50 to −0.10)). …”
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5619
Du brie de Charlemagne à la tarte renversée des sœurs Tatin : essai d’analyse des légendes culinaires et de leurs usages
Published 2019-12-01“…These stories are generally dubious and, more often than not, completely and indisputably false. …”
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5620
CONFRONTATION AND MUTUAL REFLECTION OF TWO WORLDS IN “THE GRASS DANCER” BY SUSAN POWER
Published 2023-05-01“…The main purpose of this article is to outline a coherent theoretical and empirical model of multi-level functioning of Dakota national identity concept in the novel “The Grass Dancer” by Susan Power. …”
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