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4722
Genome-wide association studies in suicidology — analysis of main results
Published 2019-12-01“…We consider that more research is needed in all three directions with involvement of NGS approaches, in particular whole-exome sequencing.…”
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4723
A systematic scoping review reveals that geographic and taxonomic patterns influence the scientific and societal interest in urban soil microbial diversity
Published 2025-02-01“…By coupling bibliometrics with statistical modelling we found that soil microbial traits such as biomass and respiration and omics techniques attract the interest of the scientific community while multi-taxa and time-course studies appeal more to the general public.…”
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4724
The Histone Deacetylase Family: Structural Features and Application of Combined Computational Methods
Published 2024-05-01“…However, their non-selective toxicity necessitates ongoing research into safer and more efficient class-selective or isoform-selective inhibitors. …”
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4725
Roles of Bile Acid-Activated Receptors in Monocytes-Macrophages and Dendritic Cells
Published 2025-06-01“…FXR and GPBAR1 activation generally exhibits anti-inflammatory effects, while LXR and VDR modulate a more nuanced interplay between immune responses and lipid homeostasis. …”
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4726
Analysis of the color-oversaturation problem in WCGDs and promising EOTF-based solution strategies
Published 2024-11-01“…To ensure the universality of different terminals, the image source is generally produced in a standardized gamut standard, while the terminal pursues a wider gamut and more spectacular color performance. …”
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4727
Modern Aspects of Endovascular Thrombectomy of Acute Ischemic Stroke. Selection Criteria for Endovascular Thrombectomy. Prediction Of Treatment Outcomes
Published 2024-10-01“…Endovascular thrombectomy (ET) effectively and safely recanalizes the occluded artery and restores the ischemic area in patients with acute ischemic stroke (IS), improving the clinical prognosis of stroke in the anterior and posterior circulation system, expanding the time therapeutic window from no more than 6 to 24 hours, greatly increasing the chances of functional independence and survival. …”
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4728
Timolol 0.5% versus Latanoprost 0.005% as A Single Hypotensive Drug in Glaucoma Patients: A 2-year Follow-up
Published 2024-12-01“…Although the differences were not statistically significant, latanoprost had a slightly more favorable safety profile than timolol. Conclusion: The consistently lower mean IOP values for latanoprost treatment suggest it may be more effective in reducing IOP than timolol. …”
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4729
Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance
Published 2025-01-01“…In C3G, in contrast, FHAAs often target the N-terminus, generating an acquired functional FH deficiency. Detection and monitoring FHAAs are decisive for effectively treating patients. …”
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4730
NSC-derived extracellular vesicles-mediates neuronal plasticity enhancement in vascular dementia via transferring miR-210
Published 2025-07-01“…Through a series of in vivo and in vitro gain- and loss-of-function experiments, we demonstrated that hypoxic NSC-EVs were more effective than normoxic NSC-EVs in improving cognitive function, increasing neuronal survival, enhancing synaptic plasticity and dendritic spine density, and reducing neuronal ROS production and apoptosis in the cortex and hippocampus of VD mice. …”
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4731
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4732
Microbial life-history strategies and genomic traits between pristine and cropland soils
Published 2025-05-01“…Conversely, pristine soils tend to host communities aligned with more candidate K-strategies marked by high resource use potentials. …”
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4733
A novel filament design for improving fused filament fabrication of continuous fiber composites
Published 2025-07-01“…Of further concern, the printed material generally exhibits low interlaminar tensile strength. …”
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4734
Binding Energies of Small Interstellar Molecules on Neutral and Charged Amorphous Solid Water Surfaces
Published 2025-01-01“…The interstellar medium (ISM) is all but empty. To date, more than 300 molecules have already been discovered. …”
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4735
Prospects of Using Distributed Ledger Technology to Automatize State Financial Control
Published 2018-10-01“…The expected result of the implementation of these proposals is estimated as more than 50% of the annual violations identified by the state audit institutions.…”
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4736
A Further Exploration of the Elements of ICU Patient Experience in the Chinese Context: A Descriptive Qualitative Study
Published 2025-06-01“…However, existing patient-reported experience measures often draw from general inpatient populations, lacking specificity to the ICU context. …”
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4737
Integrating high-content imaging and chemical genetics to probe host cellular pathways critical for Yersinia pestis infection.
Published 2013-01-01“…Together, our results suggest that phagocytosis is the major stimulus for NF-κB activation in response to Y. pestis infection, and that Y. pestis entry into macrophages may involve the participation of protein kinases such as PI3K and PKC. More importantly, the automated image-based screening platform described here can be applied to the study of other bacteria in general and, in combination with chemical genetic screening, can be used to identify host cell functions facilitating the identification of novel antibacterial therapeutics.…”
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4738
Trends in adult physical fitness in China: an analysis of national monitoring reports (2000–2020)
Published 2025-05-01“…It should consider adding a physical literacy monitoring component, utilizing public goods attributes, to promote sustainable change and reach more adults.…”
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4739
Main indicators of the credit organizations of the Russian Federation: vectors of changes
Published 2017-05-01“…You must take into account a broader set of indicators, which allows to make more accurate conclusions about the vectors of change in the banking business in General. …”
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4740
The treatment of patients with asthma and comorbidity.
Published 2018-04-01“…The complex use of L-arginine and TB preparations against a background of the basic therapy in A+DM2T patients produced a better control over the disease, a more rapid elimination of obstruction manifestations, achievement and prolongation of the clinical spirographic remission, an improvement of the quality of life, correction of disturbances in haemocoagulation, fibrinolysis and the functional state of endothelium.…”
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