Systematic metabolic engineering enables highly efficient production of vitamin A in Saccharomyces cerevisiae by Yi Shi, Shuhuan Lu, Xiao Zhou, Xinhui Wang, Chenglong Zhang, Nan Wu, Tianyu Dong, Shilong Xing, Ying Wang, Wenhai Xiao, Mingdong Yao

“…Vitamin A is a micronutrient critical for versatile biological functions and has been widely used in the food, cosmetics, pharmaceutical, and nutraceutical industries. …”
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Optimized enrichment of murine blood–brain barrier vessels with a critical focus on network hierarchy in post-collection analysis by Hanaa Abdelazim, Audra Barnes, James Stupin, Ranah Hasson, Carmen Muñoz-Ballester, Kenneth L. Young, Stefanie Robel, James W. Smyth, Samy Lamouille, John C. Chappell

“…This vital role in neurological health and function has garnered significant attention from the scientific community and inspired methodology for enriching BBB capillaries. …”
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Short-term mating success in relation to fluctuating wing asymmetry in the male azure damselfly Coenagrion puella by Ken M. Mauser, Jann Baumeyer, Shahab Eshghi, Stanislav N. Gorb, Alessandro Manfrin, Carsten A. Brühl

“…In these individuals, the cell shape asymmetry was more pronounced in the distal part of the wing than in the proximal part. …”
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Identifying unimodal finite mixture models in data sets using distribution shifting – A novel approach by Paul Allen Williams, Emily K. Roberts, Quynh-Anh Nguyen, Kamal Rahmouni

“…However, if the number data distribution is represented by more than one distribution, the transformed function can result in deformation of the volume distribution and possibly the appearance of additional modes as compared to a single distribution. …”
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Welgelegen by Gerdy Alette VERSCHUURE-STUIP

“…In this study the word historic country estate is addressing the house and its garden as an ensemble and this is used for country houses (landgoederen) with a more rural function, as well as for suburban villas (buitenplaatsen) referring to houses for recreation and pleasure. …”
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Uncertainty management in multiobjective electric vehicle integrated optimal power flow based hydrothermal scheduling of renewable power system for environmental sustainability by Susanta Dutta, Siddhartha Ghosh, Tushnik Sarkar, Provas Kumar Roy, Chandan Paul, Ruba Abu Khurma, Mohd Asif Shah, Saurav Mallik

“…Moreover, an analysis of variance (ANOVA) test and box plot are used to thoroughly investigate this data to provide a more precise assessment of QOSCA’s robustness. After integrating wind-solar and EV, the numerical analysis for IEEE 57 bus and IEEE 118-bus utilizing QOSCA for single objective over generation cost is reduced by 21%, emission is reduced by 17.5%, APL is reduced by 0.17% and 2.59%. …”
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Crude Radix Aconiti Lateralis Preparata (Fuzi) with Glycyrrhiza Reduces Inflammation and Ventricular Remodeling in Mice through the TLR4/NF-κB Pathway by Ping Yan, Wen Mao, Lushuai Jin, Mingsun Fang, Xia Liu, Jiali Lang, Lu Jin, Beibei Cao, Qiyang Shou, Huiying Fu

“…CFZ+GC was more effective than CFZ and PFZ, whereas CFZ had higher toxicity than CFZ+GC and PFZ. …”
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Deep sequencing reveals distinct microRNA-mRNA signatures that differentiate pancreatic neuroendocrine tumor from non-diseased pancreas tissue by N Matyasovska, N Valkova, M Gala, S Bendikova, A Abdulhamed, V. Palicka, Neil Renwick, Pavol Čekan, Evan Paul

“…Then we crossed a list of differentially expressed mRNAs with a list of in silico predicted mRNA targets of the most and least abundant miRs to generate high probability miR-mRNA interaction networks. …”
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Neocarzilin A induces apoptosis and mitochondrial disturbance by targeting reticulon 4-mediated endoplasmic reticulum stress by A. T. Jauch, J. Sailer, J. Braun, E. Czeslik, J. Geyer, C. Eberhagen, A. M. Vollmar, H. Zischka, S. A. Sieber, S. Zahler

“…We here additionally demonstrate the perturbation of mitochondrial functions (fragmentation of mitochondrial networks, ultrastructural changes, increased Opa1 splicing, loss of mitochondrial membrane potential, and excessive ROS generation) upon treatment with NCA. …”
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Developments and Applications of Liver-on-a-Chip Technology—Current Status and Future Prospects by Joseph Mugaanyi, Jing Huang, Jiongze Fang, Arthur Musinguzi, Caide Lu, Zaozao Chen

“…While challenges remain, such as vascularization and long-term function, ongoing advancements are paving the way toward clinical and pharmaceutical integration. …”
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The impact of tricuspid regurgitation on timing pulmonary valve replacement in ACHD patients after tetralogy of Fallot repair by Gianluca Brancaccio, Veronica Bordonaro, Matteo Trezzi, Marcello Chinali, Delia Fugallo, Carolina D'Anna, Veronica Lisignoli, Marin Verrengia, Fabio Miraldi, Gianfranco Butera, Roberta Iacobelli, Benedetta Leonardi, Claudia Montanaro, Aurelio Secinaro, Lorenzo Galletti

“…Background: The emerging role of tricuspid regurgitation in the long-term outcome of the general population, poses the need for a review of its impact on patients with TOF and the timing for surgical PVR. …”
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Physical activity in kidney transplant recipients: benefits, barriers, interventions by Martyna Skweres, Mateusz Nieczyporuk, Szymon Pucyło, Gabriela Piotrowska, Katarzyna Ceglarz, Jan Pielaciński, Aleksander Rudnik, Kinga Sikora, Aleksandra Sikora

“…Exercise interventions, leading to improved physical functioning both pre- and post-transplant, have been demonstrated to lead to improved muscle strength, overall physical functioning, as well as cardiorespiratory performance. …”
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Effect of cutting parameters and tool coating on residual stress and cutting temperature in dry hard turning of AISI 52100 steel using finite element method by Sandip Mane, Rajkumar Bhimgonda Patil, Md Irfanul Haque Siddiqui, Choon Kit Chan, Yong Xu

“…The thermal performance of coated carbide tools; more specifically, the performance of titanium nitride (TiN), titanium carbonitride (TiCN), and aluminum oxide (Al2O3) coating layers were examined. …”
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Mental health and well-being of older adults living with HIV in sub-Saharan Africa: a systematic review by Charles R J C Newton, Amina A Abubakar, Patrick Nzivo Mwangala, Adam Mabrouk, Ryan Wagner

“…Future work should have sufficiently large samples of PLWH50+, engage appropriate comparison groups, harmonise the measurement of these outcomes using a standardised methodology to generate more robust prevalence estimates and confirm predictors.PROSPERO registration number CRD42020145791.…”
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Disinfection Performance Improvement of UV Reactor by Baffle Design by Nakwon Jo, Woochul Hwang

“…This method was implemented as a user-defined function and integrated into the commercial CFD software ANSYS CFX 2023R1. …”
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An Overview of Heavy Metal Contamination of Water and Its Effect on Human Health by Danjuma, M.S., Abdulkadir, B.

“…The continuous industrial activities that generate metals have led to their wide distribution in the environment which raised a concern over the effects of such metals on human health and the environment itself. …”
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A Refined Terrace Extraction Method Based on a Local Optimization Model Using GF-2 Images by Guobin Kan, Jie Gong, Bao Wang, Xia Li, Jing Shi, Yutao Ma, Wei Wei, Jun Zhang

“…The model structure and loss function were adjusted accordingly to achieve high-quality terrace mapping results. …”
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Muscarinic acetylcholine receptor activated effectors in principal neurons of the rat basolateral amygdala by Todd J. Sahagian, Scott W. Harden, Jennifer L. Bizon, Jennifer L. Bizon, Barry Setlow, Barry Setlow, Charles J. Frazier, Charles J. Frazier

“…Improved understanding of these effectors will provide potentially valuable new insights on the wide range of mechanisms through which cholinergic system dysfunction can lead to impaired executive function.…”
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Mobile Robot Path Planning Based on Fused Multi-Strategy White Shark Optimisation Algorithm by Dazhang You, Junjie Yu, Zhiyuan Jia, Yepeng Zhang, Zhiyuan Yang

“…Path length and path smoothness are used as fitness evaluation metrics, and an evaluation function is established in conjunction with a non-complete model that reflects actual motion to assess the effectiveness of path planning. …”
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A quasi affine transformation evolution algorithm with evolution matrix selection operation for parameter estimation of proton exchange membrane fuel cells by Mohammad Aljaidi, Pradeep Jangir, Sunilkumar P. Agrawal, Sundaram B. Pandya, Anil Parmar, Samar Hussni Anbarkhan, Laith Abualigah

“…It was also computationally more efficient, cutting runtime in half compared to other methods. …”
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