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4421
NeuroScale: evolutional scale-based protein language models enable prediction of neuropeptides
Published 2025-05-01“…Abstract Background Neuropeptides (NPs) are critical signaling molecules involved in various physiological and behavioral processes, including development, metabolism, and memory. They function within both the nervous and endocrine systems and have emerged as promising therapeutic targets for a range of diseases. …”
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4422
Diagnostic information in GP referral letters to a memory clinic: a retrospective cohort study
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4423
Research on Target Detection Algorithm for Solder Joint Defects Based on the Improved YOLOv8
Published 2025-01-01“…Firstly, the FasterNet module was used to improve the C2f module of the baseline model, and the Efficient Multi-Scale Attention (EMA) attention mechanism was integrated to reduce model parameters and make the algorithm pay more attention to the solder joint targets. Secondly, the neck network of the baseline model was reconstructed and the Slide Loss function was introduced. …”
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4424
BIOFEEDBACK AS A METHOD FOR STUDENTS’ MENTAL STATE ASSESSMENT
Published 2017-09-01“…Neurotechnologies based on the principles of a nervous system functioning are being introduced into modern educational process more and more actively. …”
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4425
Eff-ReLU-Net: a deep learning framework for multiclass wound classification
Published 2025-07-01“…This work proposed Eff-ReLU-Net, an improved EfficientNet-B0-based deep learning model for accurately identifying multiple categories of wounds. More precisely, we introduced the ReLU activation function over the Swish in our Eff-ReLU-Net because of its simplicity, reliability, and efficiency. …”
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4426
Comparing the costs and detectability of bobcat using scat‐detecting dog and remote camera surveys in central Wisconsin
Published 2015-03-01“…We recommend cameras as a generally more cost‐efficient bobcat survey method, and we advise against relying on the strength of an individual dog's response as a means of screening samples for genetic analysis. …”
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4427
The correlation between positive rate of antibody or DNA and children’s age with suspected Mycoplasma pneumoniae infection
Published 2025-05-01“…Laboratory data showed mild elevations in inflammatory markers and normal liver function tests, reflecting the generally moderate severity of MP infections. …”
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4428
Targeting mTOR Kinase with Natural Compounds: Potent ATP-Competitive Inhibition Through Enhanced Binding Mechanisms
Published 2024-12-01“…We show the effectiveness of both compounds in forming stable complexes with the mTOR-KD, which is more effective than the mTOR-KD–ATP complex with more robust binding affinities. …”
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4429
Transposon insertion sequencing reveals novel hypermutator genes in Acinetobacter baumannii
Published 2025-08-01“…Bacteria with high mutation rates have a survival advantage in some stressful environments because they generate beneficial mutations more frequently. “Hypermutators” are bacterial strains that carry gene inactivations that increase general mutation rates. …”
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4430
The potential of artificial intelligence in business
Published 2024-07-01“…The authors paid attention to such relatively little–studied aspects of the use of artificial intelligence as the modernization of business processes in all sectors of the economy; improving the labor market through new forms of employment; optimization of migration policy; increasing the efficiency of the institution of self–employment in general and in terms of pension provision for the self–employed in particular; optimization of the size of the «shadow economy»; improvement of entrepreneurial activity through more complete implementation of the functions of an entrepreneur. …”
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4431
Principles of Arranging Independent Appraisal of Competences and Professional Development of Employees in Organization
Published 2023-07-01“…Preliminary independent appraisal of competence possession can provide efficient training of workers, which fosters the development of staff potential and sustainable functioning of then organization in general.…”
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4432
Are Visual Peripheries Forever Young?
Published 2015-01-01“…While peripheral processing chiefly carries information about motion stimuli features and redirects foveal attention to new objects, it can also take over functions typical for central vision. Here I review the data showing the plasticity of peripheral vision found in functional, developmental, and comparative studies. …”
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4433
Ground robot technologies in wildfire risk reduction. The viewpoint of the fire service
Published 2025-04-01“…Results: 92 end-user-related developments were categorised into particular elements of wildfire response process. 31 development directions related to technology providers have been assigned to general robot functionalities: ensuring safety of firefighters, shaping situational awareness, and supporting firefighting systems. …”
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4434
The competition with a concurrent cognitive task affects posturographic measures in patients with Parkinson disease
Published 2015-11-01“…Our study showed that adding a cognitive task is even more effective. Static posturographic data should be carefully overgeneralized to infer functional balance impairments.…”
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4435
Diagnostic value of blood urea and bilirubin levels determination in patients with gastroduodenal zone diseases
Published 2017-12-01“…The bilirubin concentration decrease was more pronounced (37.1 % vs. 3.5 %) and significant (p < 0.05) in patients with HP-aGDP. …”
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4436
Phylogenetic reconstruction of orthology, paralogy, and conserved synteny for dog and human.
Published 2006-09-01“…Using PhyOP to investigate orthologues and paralogues in the human and dog genomes, we found that the human assembly contains 3-fold more gene duplications than the dog. Species-specific duplicate genes, or "in-paralogues," are generally shorter and have fewer exons than 1:1 orthologues, which is consistent with selective constraints and mutation biases based on the sizes of duplicated genes. …”
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4437
Trends in the epidemiology of chronic kidney disease in patients with diabetes in Russian Federation according to the Federal diabetes register (2010–2022)
Published 2023-11-01“…Analysis of the structure of glucose-lowering therapy in T2DM patients and CKD indicates a more frequent prescription of drugs from the group of SGLT-2 inhibitors, DPP-4 inhibitors, and GLP-1 receptor antagonists compared to the general cohort of T2DM. …”
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4438
Evaluation of the efficacy of high molecular weight hyaluronic acid with chondroitin sulfate in post-traumatic knee osteoarthritis
Published 2024-08-01“…In patients with stage III knee OA, double injections of HLA with HS were more effective. The maximum pain reduction and functional improvement were observed in the first 3 months after local injection therapy.…”
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4439
Right-sided hemicolectomy in 90-year-old patient with cecum cancer
Published 2013-04-01“…Purpose of the work is to describe a case of radical treatment of cecum cancer in 90-year-old patient. It is generally known that most of the patients with malignant tumors are people of older age groups. …”
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4440
Development and Validation of a Risk Prediction Model Based on Inflammatory and Nutritional Composite Indicators for Posthepatectomy Liver Failure Following Radical Resection of He...
Published 2025-04-01“…The AUC for ALBI score was 0.577 (95% CI 0.530– 0.624), indicating that this nomogram prediction model was more effective than other scoring systems in predicting the study population in our center. …”
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