The role of B lymphocyte subsets in nephrotic syndrome: functions, mechanisms, clinical significance and future perspectives by Yuheng Liao, Yuheng Liao, Yuheng Liao, Haofei Hu, Haofei Hu, Qijun Wan, Qijun Wan, Haiying Song, Haiying Song, Haiying Song

“…Age factors significantly influence B cell development, function, and therapeutic response, with notable differences between pediatric and adult patients in B cell subset distribution, treatment efficacy, and pharmacokinetics. …”
Get full text

Research Progress of DNA Methylation in Fish by Hai HUANG, Yan LU, Liu CAO

“…Differential methylation—cytosine-phosphate-guanine sites—is involved in apoptosis, epigenetic regulation, autophagy, collagen metabolism, cell membrane function, and homeobox protein generation through gene expression regulation. …”
Get full text

IDE Support of String-Embedded Languages by S. Grigorev, E. Verbitskaia, M. Polubelova, A. Ivanov, E. Mavchun

Get full text

Plumbagin, a natural derivative of 1,4-naphthoquinone, induces cyclopic phenomenon via increased apoptosis and ROS generation in the early stage of zebrafish embryos by Yeonju Lim, Chaeeun Kim, Donghyeon Kim, Myoung-Jin Kim, Ji-Woo Yu, Min-Ho Song, Yurim Kim, Junhee Son, Ji-Ho Lee, Sung-Eun Lee

“…The cyclopia induced by PL was more severe than that of the positive controls, ethanol, forskolin, and cyclopamine. …”
Get full text

Generation of transchromosomic mice harboring HLA-A/B/C and human B2M via mouse artificial chromosome and triple BAC integration by Nanami Kishima, Takashi Moriwaki, Narumi Uno, Teruhiko Suzuki, Satoshi Abe, Masaki Sugawara, Yuichi Nagashima, Kanako Kazuki, Takeshi Endo, Kyotaro Yamazaki, Wakana Nakagawa, Reika Yuno, Yui Moriguchi, Satoko Matsukura, Kazuma Tomizuka, Yasuhiro Kazuki

“…Abstract Humanized transgenic mice carrying human genes are useful for research on gene function and disease. Bacterial artificial chromosomes (BACs) that carry human genomic sequences with regulatory elements enable the expression of transgenes at physiological levels in vivo. …”
Get full text

Investigation of System Stability and the Design of a Controller based on the Transfer Function of a Quadcopter’s BLDC Motor by Barnabás Kiss, Áron Ballagi, Miklós Kuczmann

“…In this article, an LQ (linear-quadratic) controller is implemented based on the transmission function, during which the response of the controller to a unit step signal is examined. …”
Get full text

The nasal mycobiome of individuals with allergic rhinitis and asthma differs from that of healthy controls in composition, structure and function by Marcos Pérez-Losada, Marcos Pérez-Losada, Eduardo Castro-Nallar, Eduardo Castro-Nallar, Jenaro García-Huidobro, José Laerte Boechat, José Laerte Boechat, Luis Delgado, Luis Delgado, Luis Delgado, Tiago Azenha Rama, Tiago Azenha Rama, Manuela Oliveira, Manuela Oliveira

Get full text

Structural characteristics of phytoplankton functional groups in the young crab pond with different reed type rice acreages by WEN Xu, MA Xuzhou, FAN Wei, LI Xingxing, ZHONG Yingliang

“…The results showed that a total of 126 phytoplankton species were identified, and most of them belonged to Bacillariophyta, Chlorophyta and Cyanobacteria, being classified into 71 genera and eight phyla. Simultaneously, 16 dominant species were classed into 12 functional groups of R, S1, G, J, B, D, P, L_O, W_O, X2, X1 and MP. …”
Get full text

Alterations in bacterial structure and function in seawater due to Mytilus coruscus farming: implications for sustainable aquaculture management by Fenglin Wang, Fenglin Wang, Lijia Gao, Kobi Talma, Yufeng Pan, Qi Liu, Yaodong He, Zhengwei Peng, Xiumei Zhang

“…FAPROTAX functional predictions indicated the higher relative abundance of functions associated with organic matter degradation and nitrogen cycling in the AA group. …”
Get full text

GenePixKolor (GPK) Fusion: A Novel Evolutionary Algorithm-Based Optimized NFT Card Generation and Rarity Ranking Method for Gaming Tokenomics by J. Guruprakash, P. Pradeep, L. B. Krithika

“…Fusing pixel rarity with trait rarity provides a more holistic assessment of an NFT’s uniqueness, balancing functional value with visual attractiveness. …”
Get full text

Direct conversion of urine-derived cells into functional motor neuron-like cells by defined transcription factors by Hiroaki Nagai, Masayo Saito, Hidehisa Iwata

“…Herein, induced motor neuron-like cells (iMNs) were generated from UDCs by transducing transcription factors involved in motor neuron (MN) differentiation. iMNs exhibited neuronal morphology, upregulation of pan-neuron and MN markers, and MN functionality, including spontaneous calcium oscillation and bungarotoxin-positive neuromuscular junction formation, when co-cultured with myotubes. …”
Get full text

Hyperspectral Data Can Classify Plant Functional Groups Within New Zealand Hill Farm Pasture by Thomas A. Cushnahan, Miles C. E. Grafton, Diane Pearson, Thiagarajah Ramilan

“…This study used hyperspectral imagery to map hill country pasture into plant functional groups (PFGs) as a proxy for pasture quality. …”
Get full text

COMPARATIVE ANALYSIS OF THE ANTHROPOMETRIC CHARACTERISTICS, PHYSICAL PREPAREDNESS AND TECHNICAL SKILLS OF 14-YEAR-OLD BASKETBALL PLAYERS – BOYS AND GIRLS by Mariana Borukova

Get full text

Intra-abdominal pressure and residual renal function decline in peritoneal dialysis: a threshold-based investigation by Jingjing Zhang, Lei Song, Zhongwei Ma, Lina Sun, Xiaoqing Wang, Duanyan Liu, Feng Huang, Yulin Man

“…Receiver operating characteristic (ROC) curves were generated to determine the optimal threshold value. …”
Get full text

Combined transcriptome and proteome profiling reveal cell-type-specific functions of Drosophila garland and pericardial nephrocytes by Heiko Meyer, Judith Bossen, Maren Janz, Xenia Müller, Sven Künzel, Thomas Roeder, Achim Paululat

“…Factor-specific comparisons identified novel candidate proteins either expressed and secreted by the nephrocytes or sequestered by them. The data generated in this study represent a valuable basis for a more specific application of the Drosophila model in analysing renal cell function in health and disease.…”
Get full text

Large-scale urban building function mapping by integrating multi-source web-based geospatial data by Wei Chen, Yuyu Zhou, Eleanor C. Stokes, Xuesong Zhang

“…Due to the limited availability of socio-economic geospatial data, it is more challenging to map building functions than building morphological information, especially over large areas. …”
Get full text

Narrowing the gap between machine learning scoring functions and free energy perturbation using augmented data by Ísak Valsson, Matthew T. Warren, Charlotte M. Deane, Aniket Magarkar, Garrett M. Morris, Philip C. Biggin

Get full text

CROSS-SECTION GENERATION OF VARIOUS GEO-SCIENTIFIC FEATURES WITHOUT CONTOUR DIGITIZATION USING A VISUAL C++ BASED SOFTWARE APPLICATION ‘VIGAT 2005’ by Dasgupta A. R., Solanki Ajay M., Rathod Brijesh G., Srivastava Naveenchandra N., Patel Vivek R., Machhar Suresh P.

Get full text

The operational municipal solid waste management policy focuses on identifying waste generation behavior across multiple levels in mega cities, a case study by Hamed Alimoradiyan, Ahmad Hajinezhad, Hossein Yousefi, Mario Giampietro

“…Moreover, developed regions produce more waste per person, attributed to higher input (consumption) and consequently higher waste generation. …”
Get full text

Plant growth-promoting rhizobacteria on peanut seedlings (Arachis hypogaea L.): Isolation, taxonomical, and functional characterization by Ezequiel Darío Bigatton, Ibrahim Ayoub, María Ángeles Castillejo, Carolina Merlo, Carolina Vázquez, Mariela Valeria Archilla, Marina Bruno, María Paula Martín, Romina Paola Pizzolitto, Lucas Esteban Dubini, Enrique Iván Lucini, Ricardo Javier Haro

Get full text