Exploring the evolution of novel enzyme functions within structurally defined protein superfamilies. by Nicholas Furnham, Ian Sillitoe, Gemma L Holliday, Alison L Cuff, Roman A Laskowski, Christine A Orengo, Janet M Thornton

“…This has been used to generate a matrix of observed exchanges from one enzyme function to another, revealing the scale and nature of enzyme evolution and that some types of exchanges between and within E.C. classes are more prevalent than others. …”
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Microbial Community and Functional Analysis of Regionally Produced Traditional Korean Grain Vinegar by Su Jeong Lee, Sun Hee Kim, Hee-Min Gwon, Jinju Park

“…In particular, five-grain vinegar (YO) tended to generate more complex and intense flavor compounds, with uniformly elevated levels of aldehydes, acids, and ketones. …”
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A Quality Function Deployment model: Application design for sauce bottle washer by Berty Dwi Rahmawati, Igh Bayogi Putra Pradana, Buna Rizal Rachman

“…Small and Medium Enterprises (SMEs) play a crucial role in employment generation and contribute substantially to national economic development, particularly in developing countries. …”
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PO25 | Baseline thrombin generation test does not predict thrombotic events in acute leukemia: a monocentric prospective study

“…Global coagulation assays such as thrombin generation assay (TGA) may provide a more comprehensive picture of the hemostatic state. …”
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Statistical Multiscore Functional Atlas Creation for Image-Guided Deep Brain Stimulation by Xiongbiao Luo, Zhuo Zeng, Song Zheng, Jianhui Chen, Pierre Jannin

“…The experimental results show that the reproducibility of the created statistical functional atlas was more than 75% in the cross validation. …”
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Biomolecule-functionalized dental implant surfaces: Towards augmenting soft tissue integration by Ghazal Shineh, Leila Mamizadeh Janghour, Yiyun Xia, Jiayan Shao, Karan Gulati, Giselle C. Yeo, Behnam Akhavan

“…By addressing how bioengineered surfaces can be designed to actively engage with biological systems, this review provides a framework for developing next-generation implant technologies that achieve more effective and predictable PSTI, with strong potential for clinical translation.…”
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Generation and evaluation of a novel PI3K-targeting gene therapy in the failing mouse heart and healthy sheep heart by Sebastian Bass-Stringer, Daniel G. Donner, Clive N. May, Aya Matsumoto, Emma I. Masterman, Aascha A. D'Elia, Yi Ching Chen, Helen Kiriazis, Jieting Luo, Roger Chooi, Clara Liu Chung Ming, Paul Gregorevic, Colleen J. Thomas, Bianca C. Bernardo, Kate L. Weeks, Julie R. McMullen

“…The aim of this study was to develop new PI3K-based gene therapies with more optimal properties for clinical translation. …”
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Mitigating malicious denial of wallet attack using attribute reduction with deep learning approach for serverless computing on next generation applications by Amal K. Alkhalifa, Mohammed Aljebreen, Rakan Alanazi, Nazir Ahmad, Sultan Alahmari, Othman Alrusaini, Ali Alqazzaz, Hassan Alkhiri

“…Serverless computing, Function-as-a-Service (FaaS), is a cloud computing (CC) system that permits developers to construct and run applications without a conventional server substructure. …”
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Function of protein ubiquitination and SUMOylation in regulating flowering time of plants: A review by Zhang Xiaolian, Zhang Jishun, Zou Jie, Zhao Jiehong, Ren Xueliang

“…According to the study of Arabidopsis genome, there are more than 1 400 genes encoding components of the ubiquitin/26S proteasome pathway. …”
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Modern Challenges to Effective Functioning of Local Self-Government (On the Example of Saint Petersburg) by V. A. Semenov, V. V. Ereshkin

“…Under the Law of the Russian Federation on amendment of the Constitution of the Russian Federation dated 14.03.2020 № 1-FCL “On improvement of regulation of separate issues of organization and functioning of public authorities” local self-government bodies were eferred to public authorities. …”
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Model organisms for investigating the functional involvement of NRF2 in non-communicable diseases by Ana I. Rojo, Brigitta Buttari, Susana Cadenas, Ana Rita Carlos, Antonio Cuadrado, Ana Sofia Falcão, Manuela G. López, Milen I. Georgiev, Anna Grochot-Przeczek, Sentiljana Gumeni, José Jimenez-Villegas, Jarosław Olav Horbanczuk, Ozlen Konu, Isabel Lastres-Becker, Anna-Liisa Levonen, Viktorija Maksimova, Charalambos Michaeloudes, Liliya V. Mihaylova, Michel Edwar Mickael, Irina Milisav, Biljana Miova, Patricia Rada, Marlene Santos, Miguel C. Seabra, Dubravka Svob Strac, Sandra Tenreiro, Ioannis P. Trougakos, Albena T. Dinkova-Kostova

“…NRF2 controls the expression of more than 250 human genes that share in their regulatory regions a cis-acting enhancer termed the antioxidant response element (ARE). …”
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Numerical Investigation of 2D Ordered Pillar Array Columns: An Algorithm of Unit-Cell Automatic Generation and the Corresponding CFD Simulation by Qihao Jiang, Stefano Rocca, Kareem Shaikhuzzaman, Simone Dimartino

“…The algorithm is developed to incorporate functional and operational constraints, which ensure that the generated structures are permeable and suitable for chromatographic separations. …”
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Enhancing Negative Film Colorization through Systematic CycleGAN Architectural Modifications: A Comprehensive Analysis of Generator and Discriminator Performance by Khaulyca Arva Artemysia Khaulyca, Arief Suryadi Satyawan Arief, Mokhammad Mirza Etnisa Haqiqi Mirza, Helfy Susilawati Helfy, Beni Wijaya Beni, Sani Moch Sopian Sani, Muhammad Ikbal Shamie Ikbal, Firman Firman

“…Modifications included the addition of residual blocks, alterations in filter quantities, activation functions, and inter-layer connections. The Evaluation was conducted qualitatively and based on generator and discriminator loss values. …”
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An updated database of virus circular RNAs provides new insights into the biogenesis mechanism of the molecule by Ping Fu, Zena Cai, Zhiyuan Zhang, Xiangxian Meng, Yousong Peng

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Development of generating heat energy from empty oil palm bunch powder in cylinder bio-stove with pyrolysis and gasification technology by Paul David Rey, Mujiyono, Didik Nurhadiyanto, Helmi Kusuma Perdana, Eddy Rusly

“…The bio-stove has been proven functional and produces stable heat energy to boil 1.5 liters of water with generated heat energy of ±110 Kcal in ±6 min, almost equal to an LPG stove, which is ±180 Kcal in ±6 min [1]. …”
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Two-stage strategic optimal planning of distributed generators and energy storage systems considering demand response program and network reconfiguration by Saleh Ba-swaimi, Renuga Verayiah, Vigna K. Ramachandaramurthy, Ahmad K. ALAhmad, Sanjeevikumar Padmanaban

“…Subsequently, the backward reduction algorithm (BRA) is employed to streamline the resulting scenarios into a more feasible and representative subset, therefore mitigating excessive computational effort. …”
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Survey of gut microbial biogeography and their functional niche in the grow-finishing swine of ordinary feeding by Lili Cao, Lili Cao, Wei Guo, Shiyu Yang, Shiyu Yang, Anum Ali Ahmad, Yuntao Dong, Cen Gong, Shuoqi Wang, Xuemin Yang, Zhentao Cheng, Zhihong Yan, Zhihong Yan, Weiwei Wang

“…Oscillospiraceae_UCG-005 in the cecum and Christensenellaceae_R-7_group in the colon were more abundant with 16.4 and 20.2% relative abundances, respectively. …”
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Absence of Adverse Effects on Pulmonary Histopathology and Functions Following Inhalation Exposure to Chloromethylisothiazolinone/Methylisothiazolinone by Sam Kacew, Esref Demir

“…It is thus evident that the inhalation data generated by the Korean Regulatory Agencies are more realistic and show that exposure to CMIT and MIT does not initiate pulmonary fibrosis. …”
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Evolution of Microbial Community Structure and Denitrifying Functional Microorganisms in the Biological Sponge Iron System by Jing Li, Huina Xie, Wei Zhao, Jie Li

“…The relative abundance of nitrifying bacteria exhibited a more complex variation, whereas the abundance of denitrifying bacteria showed a continuous upward trend. …”
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Social networks and self-function-related interpersonal impairment in problematic Facebook and internet use by Imre András Török, Robert Herold, Szabolcs Bandi, Júlia Éva Varga, Sándor Rózsa, Eszter H. Somlai, János Kállai

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